MAPK
MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.
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AMG-548 dihydrochloride (864249-60-5 free base)
AMG-548 dihydrochloride: oral p38α inhibitor, Ki: 0.5 nM; less so for p38β, Ki: 36 nM; …
Formula:
C29H29Cl2N5O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
534.48
Ref: TM-T10298L2
| 1mg | 163.00 € | ||
| 5mg | 468.00 € | ||
| 10mg | 775.00 € | ||
| 50mg | To inquire | ||
| 100mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
Morusinol
CAS:62949-93-3
Morusinol is a flavonoid extracted from the root bark of Morus alba. Morusinol has antiplatelet …
Formula:
C25H26O7
Purity:
98%
Color and Shape:
Solid
Molecular weight:
438.47
Ref: TM-TN1953
| 5mg | To inquire | ||
| 1ml*10 (DMSO) | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
Boehmenan
CAS:57296-22-7
(±)-Boehmenan inhibits PTP1B competitively (IC50=43.5µM), exhibits cytotoxicity in cancer cells, and affects mitochondria/EGFR in A549 …
Formula:
C40H40O12
Purity:
98%
Color and Shape:
Solid
Molecular weight:
712.74
Ref: TM-TN3525
| 1mg | 261.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
SJFα
CAS:2254609-27-1
SJFα (SJF alpha) degrades p38α and p38δ and can be used in cancer research.
Formula:
C59H67F2N7O11S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
1120.27
Ref: TM-T18681
| 1mg | 94.00 € | ||
| 5mg | 197.00 € | ||
| 10mg | 366.00 € | ||
| 25mg | 779.00 € | ||
| 50mg | 1,374.00 € | ||
| 1mL*10mM (DMSO) | 460.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
JTP10-△-R9 TFA
JTP10-△-R9 TFA is a selective inhibitor of JNK2 peptide (IC50: 89 nM), exhibiting 10-fold selectivity …
Formula:
C119H214F3N53O26
Purity:
98%
Color and Shape:
Solid
Molecular weight:
2860.31
Ref: TM-TP2145
| 100mg | To inquire | ||
| 500mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
p38α inhibitor 3
CAS:260428-69-1
p38α inhibitor 3 is a inhibitor of the mitogen-activated protein kinase p38α that can block …
Formula:
C19H20FNO
Purity:
99.93%
Color and Shape:
Soild
Molecular weight:
297.37
Ref: TM-T67830
| 10mg | 44.00 € | ||
| 25mg | 83.00 € | ||
| 50mg | 113.00 € | ||
| 100mg | 182.00 € | ||
| 200mg | 267.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Isocryptotanshinone
CAS:22550-15-8
Isocryptotanshinone inhibits protein tyrosine phosphatase 1B (PTP1B) activity with 50% inhibitory concentration values of 56.1±6.3 …
Formula:
C19H20O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
296.36
Ref: TM-TN1775
| 5mg | 746.00 € | ||
| 1mL*10mM (DMSO) | 765.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
OVA-E1 peptide TFA
CAS:1262750-80-0
OVA-E1 peptide TFA activates the p38 and JNK cascades similarly in mutant and wild-type thymocytes.
Formula:
C49H77F3N10O16
Purity:
98%
Color and Shape:
Solid
Molecular weight:
1119.19
Ref: TM-T38665
| 1mg | 151.00 € | ||
| 5mg | 413.00 € | ||
| 10mg | 619.00 € | ||
| 25mg | 1,112.00 € | ||
| 50mg | 1,669.00 € | ||
| 100mg | 2,503.00 € | ||
| 200mg | 3,754.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
CHPG hydrochloride
CHPG hydrochloride is a selective agonist of mGluR5.
Formula:
C8H9Cl2NO3
Purity:
98.1%
Color and Shape:
Soild
Molecular weight:
238.07
Ref: TM-T10809L
| 1mg | 92.00 € | ||
| 5mg | 183.00 € | ||
| 10mg | 274.00 € | ||
| 25mg | 439.00 € | ||
| 50mg | 624.00 € | ||
| 100mg | 830.00 € | ||
| 500mg | 1,643.00 € | ||
| 1mL*10mM (DMSO) | 167.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Samidin
CAS:477-33-8
Samidin has anti-inflammatory properties through suppression of NF-κB and AP-1-mediated-genes in lipopolysaccharide (LPS)-stimulated RAW 264.7 …
Formula:
C21H22O7
Purity:
98%
Color and Shape:
Solid
Molecular weight:
386.4
Ref: TM-TN4938
| 5mg | 453.00 € | ||
| 1mL*10mM (DMSO) | 463.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
ZINC05007751
CAS:591239-68-8
ZINC05007751 inhibits NEK6 (IC50=3.4μM), selective for NEK1/6, inactive on NEK2/7/9.
Formula:
C18H12N2O3
Purity:
97.12%
Color and Shape:
Solid
Molecular weight:
304.3
Ref: TM-T9880
| 1mg | 56.00 € | ||
| 2mg | 80.00 € | ||
| 5mg | 119.00 € | ||
| 10mg | 185.00 € | ||
| 25mg | 349.00 € | ||
| 50mg | 560.00 € | ||
| 100mg | 799.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
D-JNKI-1
CAS:1445179-97-4
D-JNKI-1 (AM-111) is a highly effective and cell-permeable peptide inhibitor.
Formula:
C164H286N66O40
Purity:
98%
Color and Shape:
Solid
Molecular weight:
3822.44
Ref: TM-T10937
| 50mg | 1,076.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Broussonin A
CAS:73731-87-0
Broussonins A, new phytoalexins from mulberry, exhibit estrogenic effects, inhibit adipogenesis and reduce inflammatory iNOS …
Formula:
C16H18O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
258.317
Ref: TM-TN3539
| 5mg | 491.00 € | ||
| 1mL*10mM (DMSO) | 501.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
KRASG12C IN-14
KRASG12C IN-14 (compound 15), a potent inhibitor specifically designed for the KRAS G12C mutation, exhibits …
Formula:
C51H65F4N9O9S2
Color and Shape:
Liquid
Molecular weight:
1088.24
Ref: TM-T200204
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
Quercetin 3,4'-dimethyl ether
CAS:33429-83-3
Quercetin 3,4'-dimethyl ether: anti-lipid peroxidation (IC50=0.3μM), anti-inflammatory, pro-apoptotic, anti-leukemia potential.
Formula:
C17H14O7
Purity:
98%
Color and Shape:
Solid
Molecular weight:
330.29
Ref: TM-TN4877
| 5mg | 510.00 € | ||
| 1mL*10mM (DMSO) | 519.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
BAY-6035
CAS:2247890-13-5
BAY-6035 is an inhibitor of SET and MYND domain-containing protein 3 (SMYD3). BAY-6035 has more …
Formula:
C22H28N4O3
Purity:
99.39%
Color and Shape:
Liquid
Molecular weight:
396.48
Ref: TM-T36631
| 5mg | 52.00 € | ||
| 10mg | 82.00 € | ||
| 25mg | 151.00 € | ||
| 50mg | 238.00 € | ||
| 100mg | To inquire | ||
| 1mL*10mM (DMSO) | 58.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
4,10-Aromadendranediol
CAS:70051-38-6
4,10-Aromadendranediol exhibits neurite outgrowth-inducing activity in neurons via activation of the ERK signaling pathway, which …
Formula:
C15H26O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
238.371
Ref: TM-TN2995
| 5mg | 586.00 € | ||
| 1mL*10mM (DMSO) | 595.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Ras Inhibitory Peptide acetate
Ras Inhibitory Peptide acetate, involved in cancer-related Ras signaling.
Formula:
C55H95N19O13
Purity:
96.63%
Color and Shape:
Solid
Molecular weight:
1230.46
Ref: TM-T37422L
| 1mg | 187.00 € | ||
| 5mg | 420.00 € | ||
| 10mg | 620.00 € | ||
| 25mg | 947.00 € | ||
| 50mg | 1,324.00 € | ||
| 100mg | 1,784.00 € | ||
| 200mg | 1,367.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
B-Raf IN 2
CAS:2649372-20-1
B-Raf IN 2, compound Ia, is a highly effective and specific inhibitor of BRAF. It …
Formula:
C20H17F2N5O4S
Purity:
98.2%
Color and Shape:
Liquid
Molecular weight:
461.44
Ref: TM-T40284
| 1mg | 56.00 € | ||
| 5mg | 122.00 € | ||
| 10mg | 184.00 € | ||
| 25mg | 328.00 € | ||
| 50mg | 460.00 € | ||
| 100mg | 647.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Peonidin chloride
CAS:134-01-0
Peonidin chloride has antioxidant activity.
Formula:
C16H13ClO6
Purity:
98%
Color and Shape:
Solid
Molecular weight:
336.72
Ref: TM-TN1062
| 1mg | 153.00 € | ||
| 5mg | 568.00 € | ||
| 10mg | 1,063.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
