MAPK
MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.
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FAM49B (190-198) mouse
CAS:1588388-60-6
FAM49B (190-198) mouse represents a peptide fragment of the mitochondria-localized protein FAM49B, which is instrumental …
Formula:
C49H71N9O14S
Color and Shape:
Liquid
Molecular weight:
1042.2
Ref: TM-TP2834
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
DS03090629
DS03090629, an orally active MEK inhibitor, functions by competitively inhibiting MEK activity in the presence …
Formula:
C25H26ClN5O2
Color and Shape:
Liquid
Molecular weight:
463.96
Ref: TM-T200155
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
JNK-1-IN-3
JNK-1-IN-3 (Compound 9e) acts as a JNK1 inhibitor, both reducing JNK1 gene expression and lowering …
Formula:
C19H17FN4O3
Color and Shape:
Liquid
Molecular weight:
368.36
Ref: TM-T200221
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
ERK5-IN-5
CAS:2318792-30-0
ERK5-IN-5 is extracellular signal-regulated kinase 5 (ERK5) inhibitor with anticancer activity anticonvulsant activity inhibits A549 …
Formula:
C19H16ClN3O
Purity:
99.77%
Color and Shape:
Soild
Molecular weight:
337.8
Ref: TM-T77734
| 1mg | 85.00 € | ||
| 2mg | 111.00 € | ||
| 5mg | 179.00 € | ||
| 10mg | 277.00 € | ||
| 25mg | 558.00 € | ||
| 50mg | 910.00 € | ||
| 100mg | 1,443.00 € | ||
| 500mg | 2,801.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
MEK/RAF-IN-1
MEK/RAF-IN-1 (Compound 16b) serves as an inhibitor targeting both MEK and RAF, demonstrating potent efficacy …
Formula:
C28H29F3N6O5S
Color and Shape:
Liquid
Molecular weight:
618.63
Ref: TM-T200267
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
WYE-687
CAS:1062161-90-3
WYE-687 is a selective mTOR inhibitor (IC50: 7 nM), over 100x more selective for mTOR …
Formula:
C28H32N8O3
Purity:
98.98%
Color and Shape:
Solid
Molecular weight:
528.61
Ref: TM-T6732
| 5mg | 39.00 € | ||
| 10mg | 58.00 € | ||
| 25mg | 111.00 € | ||
| 50mg | To inquire | ||
| 100mg | To inquire | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
AZ7550 trimesylate salt
CAS:2319837-99-3
AZ7550 trimesylate salt (AZ7550 Mesylate) is the active metabolite of ositinib, AZ7550 inhibits IGF1R activity …
Formula:
C30H43N7O11S3
Purity:
99.24%
Color and Shape:
Solid
Molecular weight:
773.9
Ref: TM-T13564L2
| 1mg | 147.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Lucidenic acid D
CAS:98665-16-8
Lucidenic acid D2 is a nartural product from G. lucidum AF.
Formula:
C29H38O8
Purity:
98%
Color and Shape:
Solid
Molecular weight:
514.61
Ref: TM-TN1882
| 5mg | 901.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
MBP MAPK Substrate acetate
MBP MAPK Substrate acetate can be used as an exogenous substrate for MAPK.
Formula:
C41H74N18O13
Purity:
99.71%
Color and Shape:
Liquid
Molecular weight:
1026.56827
Ref: TM-T38796L
| 1mg | 152.00 € | ||
| 2mg | 204.00 € | ||
| 5mg | 290.00 € | ||
| 10mg | 419.00 € | ||
| 25mg | 634.00 € | ||
| 50mg | 872.00 € | ||
| 100mg | 1,162.00 € | ||
| 200mg | 1,574.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
2-Hydroxy-3-methylanthraquinone
CAS:17241-40-6
2-Hydroxy-3-methylanthraquinone triggers U937 cell apoptosis via p-p38MAPK, downregulates p-ERK1/2, and activates caspase-3.
Formula:
C15H10O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
238.24
Ref: TM-TN1211
| 5mg | 519.00 € | ||
| 1mL*10mM (DMSO) | 538.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Manassantin B
CAS:88497-88-5
Manassantin B is a potent inhibitor of NF-κB activation by the suppression of transciptional activity …
Formula:
C41H48O11
Purity:
98%
Color and Shape:
Solid
Molecular weight:
716.81
Ref: TM-TN4490
| 5mg | 255.00 € | ||
| 1mL*10mM (DMSO) | 227.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Cearoin
CAS:52811-37-7
Cearoin suppresses inflammation, allergies, and NO production, and triggers autophagy and apoptosis in neuroblastomas via …
Formula:
C14H12O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
244.24
Ref: TM-TN3614
| 5mg | 495.00 € | ||
| 1mL*10mM (DMSO) | 519.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
NST-628
CAS:3002056-30-3
NST-628 is a pan-RAF-MEK molecular glue that prevents RAF from phosphorylating and activating MEK. NST-628 …
Formula:
C22H18F2N4O5S
Purity:
98.62%
Color and Shape:
Solid
Molecular weight:
488.46
Ref: TM-T87041
| 1mg | 219.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Lyoniresinol
CAS:14464-90-5
Lyoniresinol, a lignan from Tarenna attenuata, has antioxidant and anti-melanogenic properties, with an IC50 of …
Formula:
C22H28O8
Purity:
98%
Color and Shape:
Solid
Molecular weight:
420.45
Ref: TM-TN4469
| 5mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
6,4'-Dihydroxy-7-methoxyflavanone
CAS:189689-32-5
Active compound from Dalbergia odorifera with antioxidant, anti-inflammatory, neuroprotective properties, may treat bone diseases.
Formula:
C16H14O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
286.28
Ref: TM-TN3144
| 1mg | 230.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Cimiside E
CAS:154822-57-8
Cimiside E tamps inflammation, halts gastric cancer growth, and triggers cell death by modulating PPAR-γ, …
Formula:
C35H54O8
Purity:
98%
Color and Shape:
Solid
Molecular weight:
602.809
Ref: TM-TN3655
| 1mg | To inquire | ||
| 5mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
Shizukaol B
CAS:142279-40-1
Shizukaol B: anti-inflammatory, inhibits NO & JNK-AP-1 in LPS-microglia, low toxicity, anti-HIV, hampers monocyte-HUVEC adhesion.
Formula:
C40H44O13
Purity:
98%
Color and Shape:
Solid
Molecular weight:
732.77
Ref: TM-TN5011
| 1mg | 300.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Xl-281
CAS:870603-16-0
XL-281: potent oral RAF kinase inhibitor, effective on wild-type and mutants, reduces tumor growth and …
Formula:
C24H19ClN4O4
Purity:
95.77% - 98.60%
Color and Shape:
Liquid
Molecular weight:
462.89
Ref: TM-T68170
| 1mg | 274.00 € | ||
| 5mg | 673.00 € | ||
| 10mg | 920.00 € | ||
| 25mg | 1,417.00 € | ||
| 50mg | 1,846.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Patritumab
CAS:1262787-83-6
Patritumab (U3-1287), an anti-HER3 antibody, may inhibit tumor growth and cancer cell division in non-small …
Purity:
95.2%
Color and Shape:
Liquid
Molecular weight:
146.97 kDa
Ref: TM-T76796
| 1mg | 279.00 € | ||
| 5mg | 739.00 € | ||
| 10mg | 1,153.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
(S)-BAY-293
CAS:2244904-69-4
(S)-BAY-293 is a potent pan-KRAS inhibitor for the study of primary non-small lung and pancreatic …
Formula:
C25H28N4O2S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
448.58
Ref: TM-T41214
| 5mg | 660.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
