MAPK
MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.
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JTP10-△-TATi TFA
JTP10-△-TATi TFA is a selective inhibitor of JNK2 peptide (IC50: 92 nM), exhibiting 10-fold selectivity …
Formula:
C120H213F3N48O28
Purity:
98%
Color and Shape:
Solid
Molecular weight:
2833.28
Ref: TM-TP2146
| 100mg | To inquire | ||
| 500mg | To inquire |
Estimated delivery in United States, on Monday 12 May 2025
Ro-3201195
CAS:249937-52-8
Ro-3201195 is a novel orally available p38 MAPK inhibitor with high selectivity.
Formula:
C19H18FN3O4
Purity:
100%
Color and Shape:
Solid
Molecular weight:
371.36
Ref: TM-T68134
| 1mg | 128.00 € | ||
| 5mg | 304.00 € | ||
| 10mg | 457.00 € | ||
| 25mg | 747.00 € | ||
| 50mg | 1,026.00 € | ||
| 100mg | 1,406.00 € | ||
| 500mg | 2,812.00 € |
Estimated delivery in United States, on Monday 12 May 2025
JTP10-△-R9 TFA
JTP10-△-R9 TFA is a selective inhibitor of JNK2 peptide (IC50: 89 nM), exhibiting 10-fold selectivity …
Formula:
C119H214F3N53O26
Purity:
98%
Color and Shape:
Solid
Molecular weight:
2860.31
Ref: TM-TP2145
| 100mg | To inquire | ||
| 500mg | To inquire |
Estimated delivery in United States, on Monday 12 May 2025
p38α inhibitor 3
CAS:260428-69-1
p38α inhibitor 3 is a inhibitor of the mitogen-activated protein kinase p38α that can block …
Formula:
C19H20FNO
Purity:
99.93%
Color and Shape:
Soild
Molecular weight:
297.37
Ref: TM-T67830
| 10mg | 46.00 € | ||
| 25mg | 85.00 € | ||
| 50mg | 116.00 € | ||
| 100mg | 187.00 € | ||
| 200mg | 274.00 € |
Estimated delivery in United States, on Monday 12 May 2025
GNE-9815
CAS:2729996-45-4
GNE-9815 (3-(2-cyanopropan-2-yl)-N-[2-fluoro-4-methyl-5-(7-methyl-8-oxo-7,8-dihydropyrido[2,3-d]pyridazin-3-yl)phenyl]benzamide) is a high kinase-selective
Formula:
C26H22FN5O2
Purity:
98.19% - 98.73%
Color and Shape:
Liquid
Molecular weight:
455.48
Ref: TM-T9585
| 1mg | 64.00 € | ||
| 5mg | 145.00 € | ||
| 10mg | 226.00 € | ||
| 25mg | 378.00 € | ||
| 50mg | 538.00 € | ||
| 100mg | 730.00 € | ||
| 500mg | 1,464.00 € | ||
| 1mL*10mM (DMSO) | 145.00 € |
Estimated delivery in United States, on Monday 12 May 2025
SB220025
CAS:165806-53-1
SB220025 is a P38 mitogen-activated protein kinase inhibitor that inhibits p56Lck and PKC, and inhibits …
Formula:
C18H19FN6
Purity:
99.44%
Color and Shape:
Solid
Molecular weight:
338.38
Ref: TM-T28681
| 1mg | 279.00 € | ||
| 5mg | 685.00 € | ||
| 10mg | 938.00 € | ||
| 25mg | 1,444.00 € | ||
| 50mg | 1,882.00 € |
Estimated delivery in United States, on Monday 12 May 2025
Rupestonic acid
CAS:115473-63-7
Rupestonic acid is a compound in Artemisia rupestris L., a well-known traditional Uighur medicine for …
Formula:
C15H20O3
Purity:
98.07%
Color and Shape:
Solid
Molecular weight:
248.32
Ref: TM-TN2166
| 1mg | 73.00 € | ||
| 2mg | 98.00 € | ||
| 5mg | 163.00 € | ||
| 10mg | 255.00 € | ||
| 25mg | 411.00 € | ||
| 50mg | 562.00 € | ||
| 100mg | 758.00 € |
Estimated delivery in United States, on Monday 12 May 2025
Isocryptotanshinone
CAS:22550-15-8
Isocryptotanshinone inhibits protein tyrosine phosphatase 1B (PTP1B) activity with 50% inhibitory concentration values of 56.1±6.3 …
Formula:
C19H20O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
296.36
Ref: TM-TN1775
| 5mg | 750.00 € | ||
| 1mL*10mM (DMSO) | 770.00 € |
Estimated delivery in United States, on Monday 12 May 2025
MAP4K4-IN-6
MAP4K4-IN-6 (Compound 15f) is a MAP4K4 inhibitor with an IC50 of 80 nM. It reduces …
Color and Shape:
Odour Solid
Ref: TM-T200733
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 12 May 2025
OVA-E1 peptide TFA
CAS:1262750-80-0
OVA-E1 peptide TFA activates the p38 and JNK cascades similarly in mutant and wild-type thymocytes.
Formula:
C49H77F3N10O16
Purity:
98%
Color and Shape:
Solid
Molecular weight:
1119.19
Ref: TM-T38665
| 1mg | 152.00 € | ||
| 5mg | 415.00 € | ||
| 10mg | 622.00 € | ||
| 25mg | 1,119.00 € | ||
| 50mg | 1,679.00 € | ||
| 100mg | 2,520.00 € | ||
| 200mg | 3,780.00 € |
Estimated delivery in United States, on Monday 12 May 2025
6,4'-Dihydroxy-7-methoxyflavanone
CAS:189689-32-5
Active compound from Dalbergia odorifera with antioxidant, anti-inflammatory, neuroprotective properties, may treat bone diseases.
Formula:
C16H14O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
286.28
Ref: TM-TN3144
| 1mg | 230.00 € |
Estimated delivery in United States, on Monday 12 May 2025
Cyclorasin 9A5 TFA
Cyclorasin 9A5 TFA is a cell-penetrating cyclic peptide consisting of 11 residues that inhibits the …
Formula:
C75H108FN25O13·xC2HF3O2
Color and Shape:
Liquid
Molecular weight:
1586.82 (free base)
Ref: TM-TP2915
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 12 May 2025
Klotho-derived peptide 1 hydrochloride
Klotho-derived peptide 1 (KP1 human) hydrochloride inhibits the interaction between TGF-β and TGF-β receptor 2, …
Color and Shape:
Odour Solid
Ref: TM-TP2892
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 12 May 2025
RMC-6291
CAS:2641998-63-0
RMC-6291: Oral, covalent KRAS G12C inhibitor, blocks signaling, forms tri-complex with CypA, suppresses RAS activity …
Formula:
C55H78FN9O8
Purity:
98.73%
Color and Shape:
Solid
Molecular weight:
1012.26
Ref: TM-T75131
| 1mg | 159.00 € | ||
| 2mg | 226.00 € | ||
| 5mg | 373.00 € | ||
| 10mg | 635.00 € | ||
| 25mg | 1,121.00 € |
Estimated delivery in United States, on Monday 12 May 2025
MEK ligand-2
CAS:212631-56-6
MEK ligand-2, a ligand for the target protein for PROTAC (Ligand for Target Protein for …
Formula:
C13H8F3IN2O2
Color and Shape:
Liquid
Molecular weight:
408.12
Ref: TM-T201410
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 12 May 2025
Scio-323
CAS:309913-51-7
Scio-323是一种可口服的 p38丝裂原活化蛋白(MAPK)激酶抑制剂。
Formula:
C27H30FN3O4
Purity:
100.00%
Color and Shape:
Solid
Molecular weight:
479.54
Ref: TM-T68139
| 1mg | 115.00 € | ||
| 5mg | 245.00 € | ||
| 10mg | 363.00 € | ||
| 25mg | 562.00 € | ||
| 50mg | 775.00 € | ||
| 100mg | 1,035.00 € | ||
| 200mg | 1,406.00 € | ||
| 1mL*10mM (DMSO) | 294.00 € |
Estimated delivery in United States, on Monday 12 May 2025
MRTX0902
CAS:2654743-22-1
MRTX0902 is an effective and high selective inhibitor of SOS1 with an IC50 of 46 …
Formula:
C22H24N6O
Purity:
98.37%
Color and Shape:
Solid
Molecular weight:
388.47
Ref: TM-T9755
| 1mg | 95.00 € | ||
| 5mg | 202.00 € | ||
| 10mg | 298.00 € | ||
| 25mg | 630.00 € | ||
| 50mg | 1,008.00 € | ||
| 100mg | 1,644.00 € |
Estimated delivery in United States, on Monday 12 May 2025
JNK2-IN-1
JNK2-IN-1 (Compound J27), a selective JNK2 inhibitor with a dissociation constant (Kd) of 79.2 µM, …
Formula:
C30H26N4O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
522.55
Ref: TM-T78829
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 12 May 2025
HPK1-IN-4
CAS:2739844-28-9
HPK1-IN-4 is an HPK1 (MAPK41) inhibitor with an IC 50 of 0.061 nM. HPK1-IN-4 is …
Formula:
C23H26N6O3
Purity:
97.2%
Color and Shape:
Solid
Molecular weight:
434.49
Ref: TM-T40350
| 1mg | 130.00 € | ||
| 5mg | 311.00 € | ||
| 10mg | 472.00 € | ||
| 25mg | 825.00 € | ||
| 50mg | 1,130.00 € | ||
| 100mg | 1,549.00 € | ||
| 1mL*10mM (DMSO) | 344.00 € |
Estimated delivery in United States, on Monday 12 May 2025
CHPG hydrochloride
CHPG hydrochloride is a selective agonist of mGluR5.
Formula:
C8H9Cl2NO3
Purity:
98.1%
Color and Shape:
Soild
Molecular weight:
238.07
Ref: TM-T10809L
| 1mg | 56.00 € | ||
| 5mg | 116.00 € | ||
| 10mg | 168.00 € | ||
| 25mg | 269.00 € | ||
| 50mg | 383.00 € | ||
| 100mg | 510.00 € | ||
| 200mg | 692.00 € | ||
| 1mL*10mM (DMSO) | 101.00 € |
Estimated delivery in United States, on Monday 12 May 2025
