MAPK
MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.
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AS601245.2TFA (345987-15-7 free base)
CAS:345987-16-8
AS601245.2TFA (345987-15-7 free base) (AS601245.2TFA) is a cell-permeable Inhibitor of JNK (IC50s of 150, 220, …
Formula:
C24H18F6N6O4S
Purity:
98%
Color and Shape:
Soild
Molecular weight:
600.50
Ref: TM-T8661
| 1mg | 57.00 € | ||
| 2mg | 81.00 € | ||
| 5mg | 100.00 € | ||
| 10mg | 178.00 € | ||
| 25mg | 376.00 € | ||
| 50mg | 550.00 € | ||
| 100mg | 799.00 € | ||
| 500mg | 1,624.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Saponarin
CAS:20310-89-8
Saponarin (Petrocomoside) shows in vitro and in vivo hepatoprotective and antioxidant activity against CCl4-induced liver …
Formula:
C27H30O15
Purity:
98.84%
Color and Shape:
Solid
Molecular weight:
594.52
Ref: TM-TN2179
| 1mg | 78.00 € | ||
| 5mg | 184.00 € | ||
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
SL 0101-1
CAS:77307-50-7
SL0101: selective, reversible ATP-competitive RSK inhibitor, membrane-permeable, IC50=89nM, potent RSK1/2 inhibitor, Ki=1μM.
Formula:
C25H24O12
Purity:
98%
Color and Shape:
Solid
Molecular weight:
516.45
Ref: TM-T16896
| 1mg | 238.00 € | ||
| 5mg | 937.00 € | ||
| 10mg | 1,290.00 € | ||
| 500µg | 141.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Gardenin A
CAS:21187-73-5
Gardenin A shows neurotrophic effects via activating MAPK/ERK, PKC, and PKA. Gardenin A exhibits antidepressant, …
Formula:
C21H22O9
Purity:
95.15%
Color and Shape:
Solid
Molecular weight:
418.39
Ref: TM-TN4114
| 1mg | 183.00 € | ||
| 5mg | 456.00 € | ||
| 10mg | 682.00 € | ||
| 25mg | 1,050.00 € | ||
| 50mg | 1,421.00 € | ||
| 100mg | 1,850.00 € | ||
| 500mg | 3,834.00 € | ||
| 1mL*10mM (DMSO) | 500.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
ADT-007
CAS:1945941-09-2
ADT-007 is a pan-RAS inhibitor with potent anticancer activity.
Formula:
C26H24FNO5
Purity:
97.75%
Color and Shape:
Soild
Molecular weight:
449.47
Ref: TM-T85316
| 1mg | 49.00 € | ||
| 5mg | 90.00 € | ||
| 10mg | 129.00 € | ||
| 25mg | 209.00 € | ||
| 50mg | 366.00 € | ||
| 100mg | 624.00 € | ||
| 500mg | 2,359.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
PD 198306
CAS:212631-61-3
PD 198306: a MEK inhibitor with antihyperalgesic properties, reduces Streptozocin-boosted active ERK1.
Formula:
C18H16F3IN2O2
Purity:
99.75%
Color and Shape:
Solid
Molecular weight:
476.23
Ref: TM-T21980
| 1mg | 63.00 € | ||
| 5mg | 136.00 € | ||
| 10mg | 185.00 € | ||
| 25mg | 324.00 € | ||
| 50mg | 463.00 € | ||
| 100mg | 642.00 € | ||
| 500mg | 1,266.00 € | ||
| 1mL*10mM (DMSO) | 159.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Nyasol
CAS:96895-25-9
Nyasol has anti-allergy, anti-inflammatory, antifungal, and antiprotozoal properties with notable IC50 values against specific pathogens.
Formula:
C17H16O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
252.31
Ref: TM-TN4683
| 5mg | 1,689.00 € | ||
| 1mL*10mM (DMSO) | 2,074.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
AMG-548 hydrochloride (864249-60-5 free base)
AMG-548 hydrochloride is an orally active and selective p38α inhibitor (Ki: 0.5 nM) and shows …
Formula:
C29H28ClN5O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
498.02
Ref: TM-T10298
| 100mg | To inquire | ||
| 500mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
Isorhamnetin 3-O-galactoside
CAS:6743-92-6
Isorhamnetin 3-O-galactoside shows antioxidant, anti-inflammatory, neuroprotective,and barrier protective activities, it could be used as a …
Formula:
C22H22O12
Purity:
98%
Color and Shape:
Solid
Molecular weight:
478.4
Ref: TM-TN1793
| 10mg | To inquire | ||
| 1ml*10 (DMSO) | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
7,8-Didehydrocimigenol
CAS:150972-72-8
7,8-Didehydrocimigenol treats cardiovascular issues by upregulating PPAR-γ, inhibiting NF-kB, and reducing VCAM-1 in EC.
Formula:
C30H46O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
486.693
Ref: TM-TN3219
| 5mg | 518.00 € | ||
| 1mL*10mM (DMSO) | 537.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Manassantin A
CAS:88497-87-4
Manassantin A: potent HIF-1 inhibitor, guards stomach lining, curbs iNOS/NF-κB, may help treat airway diseases, …
Formula:
C42H52O11
Purity:
98%
Color and Shape:
Solid
Molecular weight:
732.867
Ref: TM-TN4489
| 10mg | 1,208.00 € | ||
| 1mL*10mM (DMSO) | 1,227.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid
CAS:57719-81-0
Ent-11alpha-Hydroxy-15-oxokaur-16-en-19-oic acid has anti-cancer activity, it induces apoptosis of human malignant cancer cells, it also …
Formula:
C20H28O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
332.44
Ref: TM-TN3931
| 5mg | 510.00 € | ||
| 1mL*10mM (DMSO) | 519.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Cristacarpin
CAS:74515-47-2
Cristacarpin targets DNA repair-deficient yeast, induces ER stress and ROS, triggers senescence in pancreatic/breast cancer …
Formula:
C21H22O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
354.402
Ref: TM-TN3719
| 5mg | 1,860.00 € | ||
| 1mL*10mM (DMSO) | 2,150.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
MC 976
CAS:129831-99-8
MC 976 is a derivative of Vitamin D3.
Formula:
C27H42O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
414.63
Ref: TM-T16023
| 1mg | 1,039.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Ganoderic acid X
CAS:86377-53-9
Ganoderic acid X is a potential Mdm2 inhibitor(K(i) = 16nM). It is a potential anticancer …
Formula:
C32H48O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
512.731
Ref: TM-TN4107
| 1mg | 274.00 € | ||
| 5mg | 1,322.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
RMC-6236
CAS:2765081-21-6
RMC-6236 is a potent RAS(ON)MULTI inhibitor with broad-spectrum inhibitory activity against RAS-GTP.Cost-effective and quality-assured.
Formula:
C44H58N8O5S
Purity:
98.24% - 99.51%
Color and Shape:
Liquid
Molecular weight:
811.05
Ref: TM-T74698
| 1mg | 277.00 € | ||
| 5mg | 733.00 € | ||
| 10mg | 1,100.00 € | ||
| 25mg | 1,845.00 € | ||
| 50mg | 2,692.00 € | ||
| 100mg | 3,848.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Z16078526
CAS:852222-94-7
Z16078526 promotes Ucp1, p38 MAPK, lipolysis, thermogenic genes, and mitochondrial activity in mouse brown adipocytes.
Formula:
C18H17N3O4S
Purity:
98.93%
Color and Shape:
Liquid
Molecular weight:
371.41
Ref: TM-T77621
| 1mg | 52.00 € | ||
| 5mg | 114.00 € | ||
| 10mg | 181.00 € | ||
| 25mg | 387.00 € | ||
| 50mg | 573.00 € | ||
| 100mg | 820.00 € | ||
| 500mg | 1,661.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
A-674563 HCl (552325-73-2(free base))
CAS:2070009-66-2
A-674563: Oral Akt inhibitor (Ki: 11 nM for Akt1), also targets PKA/Cdk2, with 10-1800x selectivity …
Formula:
C22H23ClN4O
Purity:
≥98%
Color and Shape:
Liquid
Molecular weight:
394.9
Ref: TM-T4444
| 1mg | 83.00 € | ||
| 2mg | 107.00 € | ||
| 5mg | 135.00 € | ||
| 10mg | To inquire | ||
| 50mg | To inquire | ||
| 1mL*10mM (DMSO) | 137.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
(R)-BI-2852
CAS:2375482-49-6
(R)-5-hydroxy isoindolin-1-one is an RAS protein inhibitor with antiproliferative and antitumor properties.
Formula:
C31H28N6O2
Purity:
97.78%
Color and Shape:
Soild
Molecular weight:
516.59
Ref: TM-T72084
| 1mg | 138.00 € | ||
| 5mg | 255.00 € | ||
| 10mg | 399.00 € | ||
| 25mg | 646.00 € | ||
| 50mg | 898.00 € | ||
| 100mg | 1,198.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Olomoucine
CAS:101622-51-9
Olomoucine hinders Cdk2, Cdc2, CDK5, ERK1, regulates the cell cycle, and fights melanoma; IC50s: 3-25 …
Formula:
C15H18N6O
Purity:
99.8%
Color and Shape:
White Crystalline Powder
Molecular weight:
298.34
Ref: TM-T21588
| 1mg | 66.00 € | ||
| 5mg | 145.00 € | ||
| 10mg | 227.00 € | ||
| 25mg | 455.00 € | ||
| 50mg | 662.00 € | ||
| 100mg | 846.00 € | ||
| 1mL*10mM (DMSO) | 136.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
