MAPK
MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.
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JNK-IN-13
CAS:345986-38-1
JNK-IN-13 is a JNK inhibitor that inhibits JNK3 and JNK2 and can be used in …
Formula:
C13H7ClN4S
Purity:
98.74%
Color and Shape:
Solid
Molecular weight:
286.74
Ref: TM-T77694
| 10mg | 39.00 € | ||
| 25mg | 57.00 € | ||
| 50mg | 93.00 € |
Estimated delivery in United States, on Monday 12 May 2025
B-Raf IN 2
CAS:2649372-20-1
B-Raf IN 2, compound Ia, is a highly effective and specific inhibitor of BRAF. It …
Formula:
C20H17F2N5O4S
Purity:
98.2%
Color and Shape:
Solid
Molecular weight:
461.44
Ref: TM-T40284
| 1mg | 57.00 € | ||
| 5mg | 125.00 € | ||
| 10mg | 188.00 € | ||
| 25mg | 335.00 € | ||
| 50mg | 470.00 € | ||
| 100mg | 662.00 € |
Estimated delivery in United States, on Monday 12 May 2025
Peonidin chloride
CAS:134-01-0
Peonidin chloride has antioxidant activity.
Formula:
C16H13ClO6
Purity:
98%
Color and Shape:
Solid
Molecular weight:
336.72
Ref: TM-TN1062
| 1mg | 212.00 € | ||
| 5mg | 823.00 € | ||
| 10mg | 1,539.00 € |
Estimated delivery in United States, on Monday 12 May 2025
Ras Inhibitory Peptide acetate
Ras Inhibitory Peptide acetate, involved in cancer-related Ras signaling.
Formula:
C55H95N19O13
Purity:
96.63%
Color and Shape:
Liquid
Molecular weight:
1230.46
Ref: TM-T37422L
| 1mg | 185.00 € | ||
| 5mg | 415.00 € | ||
| 10mg | 613.00 € | ||
| 25mg | 938.00 € | ||
| 50mg | 1,311.00 € | ||
| 100mg | 1,768.00 € |
Estimated delivery in United States, on Monday 12 May 2025
JNK-1-IN-2
"JNK-1-IN-2 (Compound c6) is a potent inhibitor of JNK-1 with an IC50 of 33.5 nM, …
Formula:
C16H20BrN5O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
378.27
Ref: TM-T79489
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 12 May 2025
Olomoucine
CAS:101622-51-9
Olomoucine hinders Cdk2, Cdc2, CDK5, ERK1, regulates the cell cycle, and fights melanoma; IC50s: 3-25 …
Formula:
C15H18N6O
Purity:
99.8%
Color and Shape:
White Crystalline Powder
Molecular weight:
298.34
Ref: TM-T21588
| 1mg | 66.00 € | ||
| 5mg | 144.00 € | ||
| 10mg | 227.00 € | ||
| 25mg | 455.00 € | ||
| 50mg | 663.00 € | ||
| 100mg | 847.00 € | ||
| 1mL*10mM (DMSO) | 136.00 € |
Estimated delivery in United States, on Monday 12 May 2025
Isochamaejasmine
CAS:93859-63-3
Isochamaejasmine, isolated from S.
Formula:
C30H22O10
Purity:
98%
Color and Shape:
Solid
Molecular weight:
542.49
Ref: TM-TN4271
| 1mg | 469.00 € |
Estimated delivery in United States, on Monday 12 May 2025
KRASG12C IN-14
KRASG12C IN-14 (compound 15), a potent inhibitor specifically designed for the KRAS G12C mutation, exhibits …
Formula:
C51H65F4N9O9S2
Color and Shape:
Solid
Molecular weight:
1088.24
Ref: TM-T200204
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 12 May 2025
RMC-7977
CAS:2765082-12-8
RMC-7977 is a inhibitor of the active (GTP-bound) forms of KRAS, HRAS, and NRAS with …
Formula:
C47H60N8O6S
Purity:
97.46% - 99.7%
Color and Shape:
Solid
Molecular weight:
865.09
Ref: TM-T81263
| 1mg | 245.00 € | ||
| 5mg | 612.00 € | ||
| 10mg | 938.00 € | ||
| 25mg | 1,454.00 € | ||
| 50mg | 1,882.00 € | ||
| 100mg | 2,650.00 € | ||
| 1mL*10mM (DMSO) | 937.00 € |
Estimated delivery in United States, on Monday 12 May 2025
JNK-IN-14
JNK-IN-14 is a potent inhibitor of JNK with IC50 values of 1.81 nM for JNK1, …
Formula:
C27H31N5O4S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
521.63
Ref: TM-T79754
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 12 May 2025
MHJ-627
MHJ-627, a potent inhibitor of ERK5 (MAPK7) with an IC50 value of 0.91 μM, enhances …
Formula:
C34H45BrN2O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
609.64
Ref: TM-T78796
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 12 May 2025
KRAS G12C inhibitor 60
KRAS G12C Inhibitor 60 (compound 23), a selective inhibitor targeting the Kras-G12C mutation, is utilized …
Formula:
C31H30F5N7O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
627.61
Ref: TM-T79166
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 12 May 2025
HS220
CAS:1570374-32-1
HS220 is an inhibitor of TAK1 which plays a key role in the signaling pathways …
Formula:
C18H17N3O3
Purity:
99.98%
Color and Shape:
Soild
Molecular weight:
323.35
Ref: TM-T60011
| 1mg | 49.00 € | ||
| 5mg | 110.00 € | ||
| 10mg | 170.00 € | ||
| 25mg | 280.00 € | ||
| 50mg | 373.00 € | ||
| 100mg | 510.00 € | ||
| 200mg | 700.00 € | ||
| 1mL*10mM (DMSO) | 116.00 € |
Estimated delivery in United States, on Monday 12 May 2025
STE-MEK1(13)
CAS:566872-15-9
STE-MEK1(13), a cell-permeable ERK1/2 inhibitor with IC50 values ranging from 13 to 30 μM, impedes …
Formula:
C86H153N19O17S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
1757.32
Ref: TM-T80543
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 12 May 2025
Cyclorasin 9A5
CAS:1782098-79-6
Cyclorasin 9A5 is a cell-permeable, 11-residue cyclic peptide that orthosterically disrupts the Ras-Raf protein interaction, …
Formula:
C75H108FN25O13
Purity:
98%
Color and Shape:
Solid
Molecular weight:
1586.82
Ref: TM-T82637
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 12 May 2025
FAM49B (190-198) mouse
CAS:1588388-60-6
FAM49B (190-198) mouse represents a peptide fragment of the mitochondria-localized protein FAM49B, which is instrumental …
Formula:
C49H71N9O14S
Color and Shape:
Solid
Molecular weight:
1042.2
Ref: TM-TP2834
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 12 May 2025
DS03090629
DS03090629, an orally active MEK inhibitor, functions by competitively inhibiting MEK activity in the presence …
Formula:
C25H26ClN5O2
Color and Shape:
Solid
Molecular weight:
463.96
Ref: TM-T200155
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 12 May 2025
(R)-BI-2852
CAS:2375482-49-6
(R)-5-hydroxy isoindolin-1-one is an RAS protein inhibitor with antiproliferative and antitumor properties.
Formula:
C31H28N6O2
Purity:
97.78%
Color and Shape:
Soild
Molecular weight:
516.59
Ref: TM-T72084
| 1mg | 93.00 € | ||
| 5mg | 160.00 € | ||
| 10mg | 245.00 € | ||
| 25mg | 395.00 € | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 12 May 2025
JNK-IN-12
JNK-IN-12 (compound P2) is a mitochondrial-targeted JNK inhibitor with an IC50 value of 66.3 nM, …
Formula:
C56H82N16O7
Purity:
98%
Color and Shape:
Solid
Molecular weight:
1091.35
Ref: TM-T79296
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 12 May 2025
A-674563 HCl (552325-73-2(free base))
CAS:2070009-66-2
A-674563: Oral Akt inhibitor (Ki: 11 nM for Akt1), also targets PKA/Cdk2, with 10-1800x selectivity …
Formula:
C22H23ClN4O
Purity:
≥98%
Color and Shape:
Liquid
Molecular weight:
394.9
Ref: TM-T4444
| 1mg | 85.00 € | ||
| 2mg | 109.00 € | ||
| 5mg | 138.00 € | ||
| 10mg | To inquire | ||
| 50mg | To inquire | ||
| 1mL*10mM (DMSO) | 138.00 € |
Estimated delivery in United States, on Monday 12 May 2025
