MAPK
MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.
Read more
Vacquinol-1
CAS:5428-80-8
Vacquinol-1 is an MKK4 activator, which rapidly and selectively induces glioma cell death.
Formula:
C21H21ClN2O
Purity:
98.67%
Color and Shape:
Solid
Molecular weight:
352.86
Ref: TM-T7008
| 1mg | 182.00 € | ||
| 5mg | 399.00 € | ||
| 10mg | 593.00 € | ||
| 25mg | 920.00 € | ||
| 50mg | 1,268.00 € | ||
| 100mg | 1,706.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Hirsutenone
CAS:41137-87-5
Hirsutenone has potent antioxidant activity, it shows significant free radical scavenging activity and exhibits inhibition …
Formula:
C19H20O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
328.36
Ref: TM-TN4213
| 5mg | 565.00 € | ||
| 1mL*10mM (DMSO) | 1,443.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
p38 MAP Kinase Inhibitor Ⅵ
CAS:421578-46-3
p38 MAP Kinase Inhibitor Ⅵ is a potent p38 MAP Kinase inhibitor with anti-inflammatory activity.
Formula:
C16H13FN2OS2
Purity:
97.79%
Color and Shape:
Solid
Molecular weight:
332.42
Ref: TM-T67944
| 1mg | 83.00 € | ||
| 5mg | 176.00 € | ||
| 10mg | 269.00 € | ||
| 25mg | 457.00 € | ||
| 50mg | 641.00 € | ||
| 100mg | 906.00 € | ||
| 500mg | 1,791.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Zabofloxacin hydrochloride
CAS:623574-00-5
Zabofloxacin hydrochloride is a potent and seletive bacterial type II and IV topoisomerases inhibitor, has …
Formula:
C19H21ClFN5O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
437.86
Ref: TM-T13406L
| 10mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
5α-Hydroxycostic acid
CAS:132185-83-2
5alpha-Hydroxycostic acid possesses anti-angiogenic ability by interfering the VEGF- and Ang2-related pathways, and it may …
Formula:
C15H22O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
250.33
Ref: TM-TN3139
| 1mg | 159.00 € | ||
| 5mg | 462.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Catalposide
CAS:6736-85-2
Catalposide from Catalpa ovata has antioxidant, anti-inflammatory, and anti-tumor properties.
Formula:
C22H26O12
Purity:
99.82%
Color and Shape:
Solid
Molecular weight:
482.43
Ref: TM-TN3609
| 1mg | 212.00 € | ||
| 2mg | 356.00 € | ||
| 5mg | 641.00 € | ||
| 10mg | 907.00 € | ||
| 25mg | 1,352.00 € | ||
| 50mg | 1,821.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
15-Methoxypinusolidic acid
CAS:769928-72-5
15-Methoxypinusolidic acid: anti-inflammatory, inhibits iNOS/NO, affects MAPK/NF-kappaB, stops adipogenesis and glutamate toxicity, induces apoptosis.
Formula:
C21H30O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
362.46
Ref: TM-TN2641
| 5mg | 1,872.00 € | ||
| 1mL*10mM (DMSO) | 2,250.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Laxiflorin B-4
Laxiflorin B-4, a derivative of Laxiflorin B, demonstrates increased affinity for ERK1/2 and enhanced tumor-suppressive …
Purity:
98%
Ref: TM-T81947
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
Divarasib
CAS:2417987-45-0
Divarasib (GDC-6036), an investigational KRAS G12C inhibitor for solid tumors, has an IC50 of <0.01 …
Formula:
C29H32ClF4N7O2
Purity:
98.79%
Color and Shape:
Solid
Molecular weight:
622.06
Ref: TM-T9972
| 1mg | 228.00 € | ||
| 5mg | 571.00 € | ||
| 10mg | 810.00 € | ||
| 25mg | 1,233.00 € | ||
| 50mg | 1,653.00 € | ||
| 100mg | 2,209.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Vem-L-Cy5
Vem-L-Cy5 (compound 3), a Vemurafenib-based BRAF inhibitor conjugated with the near-infrared (NIR) fluorophore cyanine-5 (Cy5), …
Formula:
C63H68F5N7O9S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
1194.31
Ref: TM-T78777
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
Akt/NF-κB/MAPK-IN-1
Akt/NF-κB/MAPK-IN-1 (compound 2m) serves as a potent, orally active inhibitor targeting NO with an IC50 …
Formula:
C38H56N2O4
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
604.86
Ref: TM-T78838
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
Antimicrobial agent-21
CAS:724746-07-0
Antimicrobial agent-21 is a potent mitogen activated protein kinase inhibitor with antibacterial, anti-inflammatory and antitumor …
Formula:
C18H13N3OS
Purity:
99.72%
Color and Shape:
Liquid
Molecular weight:
319.38
Ref: TM-T67942
| 1mg | 119.00 € | ||
| 5mg | 277.00 € | ||
| 10mg | 422.00 € | ||
| 25mg | 682.00 € | ||
| 50mg | 918.00 € | ||
| 100mg | 1,256.00 € | ||
| 500mg | 2,529.00 € | ||
| 1mL*10mM (DMSO) | 449.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
JNK2-IN-1
JNK2-IN-1 (Compound J27), a selective JNK2 inhibitor with a dissociation constant (Kd) of 79.2 µM, …
Formula:
C30H26N4O5
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
522.55
Ref: TM-T78829
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
MK2-IN-5
CAS:474713-20-7
MK2-IN-5, a pseudosubstrate of Mk2 with an inhibition constant (K_i) of 8 μM, selectively targets …
Formula:
C61H113N21O16
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
1396.68
Ref: TM-T81783
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
JNK-IN-13
CAS:345986-38-1
JNK-IN-13 is a JNK inhibitor that inhibits JNK3 and JNK2 and can be used in …
Formula:
C13H7ClN4S
Purity:
98.74%
Color and Shape:
Liquid
Molecular weight:
286.74
Ref: TM-T77694
| 10mg | 39.00 € | ||
| 25mg | 57.00 € | ||
| 50mg | 93.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Esculin sesquihydrate
CAS:66778-17-4
Esculin sesquihydrate, a coumarin glucoside with fluorescent properties and a constituent of ash bark, improves …
Formula:
C15H16O9H2O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
367.31
Ref: TM-T80631
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
Fustin
CAS:20725-03-5
Fustin is the phytogenic flavanol component of the plant Rhus verniciflua Stokes.
Formula:
C15H12O6
Purity:
98%
Color and Shape:
Solid
Molecular weight:
288.25
Ref: TM-TN1653
| 1mg | 80.00 € | ||
| 10mg | 335.00 € | ||
| 25mg | 752.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Enniatin A1
CAS:4530-21-6
Enniatin A1, a cyclic hexadepsipeptide from Fusarium, induces apoptosis and disrupts ERK, inhibiting ACAT (IC50: …
Formula:
C35H61N3O9
Purity:
98%
Color and Shape:
Solid
Molecular weight:
667.885
Ref: TM-T11201
| 1mg | 670.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
JNK-1-IN-2
"JNK-1-IN-2 (Compound c6) is a potent inhibitor of JNK-1 with an IC50 of 33.5 nM, …
Formula:
C16H20BrN5O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
378.27
Ref: TM-T79489
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
Zunsemetinib
CAS:1640282-42-3
Zunsemetinib (ATI-450) is a p38α mitogen-activated protein kinase-activated protein kinase 2 (MK2) pathway inhibitor.
Formula:
C25H22ClF2N5O3
Purity:
99.77%
Color and Shape:
Liquid
Molecular weight:
513.92
Ref: TM-T39126
| 1mg | 268.00 € | ||
| 5mg | 651.00 € | ||
| 10mg | 1,114.00 € | ||
| 25mg | 1,661.00 € | ||
| 50mg | 2,237.00 € | ||
| 100mg | 3,001.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
