MAPK
MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.
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RMC-7977
CAS:2765082-12-8
RMC-7977 is a inhibitor of the active (GTP-bound) forms of KRAS, HRAS, and NRAS with …
Formula:
C47H60N8O6S
Purity:
97.46% - 98.20%
Color and Shape:
Liquid
Molecular weight:
865.09
Ref: TM-T81263
| 1mg | 244.00 € | ||
| 5mg | 599.00 € | ||
| 10mg | 916.00 € | ||
| 25mg | 1,837.00 € | ||
| 50mg | 3,052.00 € | ||
| 100mg | 4,907.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Haginin A
CAS:74174-29-1
Haginin A inhibits hyperpigmentation and skin disorders, reduces tyrosinase/TRP-1, and has antioxidant properties.
Formula:
C17H16O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
300.31
Ref: TM-TN4179
| 5mg | 708.00 € | ||
| 1mL*10mM (DMSO) | 727.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
JNK-IN-14
JNK-IN-14 is a potent inhibitor of JNK with IC50 values of 1.81 nM for JNK1, …
Formula:
C27H31N5O4S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
521.63
Ref: TM-T79754
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
Dehydroglyasperin C
CAS:199331-35-6
Dehydroglyasperin C: strong antioxidant, cancer preventive, neuroprotector, and combats chronic diseases.
Formula:
C21H22O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
354.4
Ref: TM-TN3806
| 5mg | 822.00 € | ||
| 1mL*10mM (DMSO) | 1,383.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
6-Acetonyldihydrochelerythrine
CAS:22864-92-2
6-Acetonyldihydrochelerythrine: anti-HIV, antioxidant, induces apoptosis, cytotoxic to HCT116/SW620 cells, more effective than 5-FU. EC50=1.77µg/mL, TI=14.6.
Formula:
C24H23NO5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
405.44
Ref: TM-TN3152
| 5mg | 510.00 € | ||
| 1mL*10mM (DMSO) | 519.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
MHJ-627
MHJ-627, a potent inhibitor of ERK5 (MAPK7) with an IC50 value of 0.91 μM, enhances …
Formula:
C34H45BrN2O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
609.64
Ref: TM-T78796
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
KRAS G12C inhibitor 60
KRAS G12C Inhibitor 60 (compound 23), a selective inhibitor targeting the Kras-G12C mutation, is utilized …
Formula:
C31H30F5N7O2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
627.61
Ref: TM-T79166
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
Corylifol C
CAS:775351-91-2
Corylifol C and, to a lesser extent, xanthoangelol are potent protein kinase inhibitors (inhibitory concentration …
Formula:
C20H18O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
338.35
Ref: TM-TN3711
| 5mg | 623.00 € | ||
| 1mL*10mM (DMSO) | 633.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
SSK1
CAS:2629250-69-5
SSK1 is a senescent cell-killing and β-galactosidase-targeting precursor compound that activates phosphorylation levels of p38 …
Formula:
C31H34F2N4O18
Purity:
98.97% - 99.83%
Color and Shape:
Solid
Molecular weight:
788.61
Ref: TM-T37450
| 1mg | 199.00 € | ||
| 5mg | 497.00 € | ||
| 10mg | 717.00 € | ||
| 25mg | 1,100.00 € | ||
| 50mg | 1,470.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
CCT241161
CAS:1163719-91-2
CCT241161: oral pan-RAF inhibitor; IC50s: LCK (3 nM), CRAF (6), SRC (10), V600E-BRAF (15), BRAF …
Formula:
C28H27N7O3S
Purity:
100% - 98.48%
Color and Shape:
Solid
Molecular weight:
541.62
Ref: TM-T9638
| 1mg | 134.00 € | ||
| 5mg | 319.00 € | ||
| 10mg | 455.00 € | ||
| 25mg | 697.00 € | ||
| 50mg | 917.00 € | ||
| 100mg | 1,263.00 € | ||
| 500mg | 2,535.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Taspine
CAS:602-07-3
Taspine inhibits tumor growth, induces HUVEC apoptosis, moderates EGFR, Erk1/2, and Akt pathways, and promotes …
Formula:
C20H19NO6
Purity:
98%
Color and Shape:
Solid
Molecular weight:
369.37
Ref: TM-TN5100
| 5mg | 842.00 € | ||
| 1mL*10mM (DMSO) | 1,146.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
SB 203580 hydrochloride
CAS:869185-85-3
SB 203580 hydrochloride (Adezmapimod hydrochloride) is a p38 MAPK inhibitor that induces mitochondrial autophagy and …
Formula:
C21H17ClFN3OS
Color and Shape:
Solid
Molecular weight:
413.9
Ref: TM-T21675
| 5mg | 43.00 € | ||
| 10mg | 59.00 € | ||
| 25mg | 91.00 € | ||
| 50mg | 118.00 € | ||
| 100mg | 167.00 € | ||
| 1mL*10mM (DMSO) | 63.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Cerdulatinib hydrochloride
CAS:1369761-01-2
Cerdulatinib hydrochloride is an oral tyrosine kinase inhibitor targeting JAK1/2/3, TYK2, Syk, and 19 others …
Formula:
C20H28ClN7O3S
Purity:
99.23%
Color and Shape:
Solid
Molecular weight:
482
Ref: TM-T6104
| 2mg | 36.00 € | ||
| 5mg | 56.00 € | ||
| 10mg | 75.00 € | ||
| 25mg | 115.00 € | ||
| 50mg | 171.00 € | ||
| 100mg | 254.00 € | ||
| 200mg | 360.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Enniatin B1
CAS:19914-20-6
Enniatin B1, a Fusarium mycotoxin, crosses the blood-brain barrier and modulates ERK, NF-κB, and ACAT …
Formula:
C34H59N3O9
Purity:
98%
Color and Shape:
Solid
Molecular weight:
653.858
Ref: TM-T13680
| 1mg | 665.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Broussonin E
CAS:90902-21-9
Broussonin E could suppress inflammation by modulating macrophages activation state via inhibiting the ERK and …
Formula:
C17H20O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
288.34
Ref: TM-TN3541
| 1mg | 696.00 € | ||
| 5mg | 1,392.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Desoxo-narchinol A
CAS:53859-06-6
Desoxo-narchinol A exhibits protective effects against LPS-induced endotoxin shock and inflammation through p38 deactivation, it …
Formula:
C12H16O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
192.25
Ref: TM-TN3839
| 1mg | 397.00 € | ||
| 5mg | 1,954.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Enniatin B
CAS:917-13-5
Enniatins B decreases the activation of ERK (p44/p42).
Formula:
C33H57N3O9
Purity:
98%
Color and Shape:
Solid
Molecular weight:
639.831
Ref: TM-T13679
| 1mg | 605.00 € | ||
| 5mg | 2,681.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Bongkrekic acid
CAS:11076-19-0
Bongkrekic acid (Bongkrekic Acid (ammonium salt)) is a mitochondrial toxin secreted by Burkholderia cepacia that …
Formula:
C28H38O7
Color and Shape:
Liquid
Molecular weight:
486.6
Ref: TM-T36067
| 1mg | 1,632.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
A-674563
CAS:552325-73-2
A-674563 is an Akt1 inhibitor with Ki of 11 nM, modest potent to PKA and …
Formula:
C22H22N4O
Purity:
99.21%
Color and Shape:
Solid
Molecular weight:
358.44
Ref: TM-T6139
| 1mg | 51.00 € | ||
| 5mg | 109.00 € | ||
| 1mL*10mM (DMSO) | 123.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
GW284543
CAS:790186-68-4
GW284543 (UNC10225170) is a selective inhibitor of MEK5 .
Formula:
C23H20N2O3
Purity:
99.38%
Color and Shape:
Solid
Molecular weight:
372.42
Ref: TM-T7610
| 1mg | 35.00 € | ||
| 5mg | 73.00 € | ||
| 10mg | 102.00 € | ||
| 25mg | 182.00 € | ||
| 50mg | 304.00 € | ||
| 100mg | 489.00 € | ||
| 1mL*10mM (DMSO) | 82.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
