MAPK
MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.
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Exarafenib
CAS:2639957-39-2
Exarafenib (RAF/KIN_2787) is an oral pan-RAF inhibitor with antitumor properties, targeting MAPK signaling in cancer …
Formula:
C26H34F3N5O3
Purity:
99.26%
Color and Shape:
Liquid
Molecular weight:
521.58
Ref: TM-T63644
| 1mg | 126.00 € | ||
| 5mg | 305.00 € | ||
| 10mg | 509.00 € | ||
| 25mg | 766.00 € | ||
| 50mg | 988.00 € | ||
| 100mg | 1,350.00 € | ||
| 500mg | 2,699.00 € |
Estimated delivery in United States, on Tuesday 18 Feb 2025
Rac1-IN-3
CAS:380470-06-4
Rac1-IN-3 (Compound 2) is a Rac1 inhibitor exhibiting an inhibitory concentration 50 (IC50) of 46.1 …
Formula:
C21H23N7O2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
405.45
Ref: TM-T79869
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 18 Feb 2025
LUNA18
CAS:2676177-63-0
LUNA18 is an orally active inhibitor targeting KRAS, exhibiting potent activity with an IC50 value …
Formula:
C73H105F5N12O12
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
1437.68
Ref: TM-T79673
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 18 Feb 2025
p38-α MAPK-IN-1
CAS:443913-15-3
p38-α MAPK-IN-1 is a MAPK14 (p38-α) inhibitor with IC50 of 2300 nM and 5500 nM …
Formula:
C27H35N5O3
Purity:
99.52%
Color and Shape:
Solid
Molecular weight:
477.6
Ref: TM-T12347
| 1mg | 87.00 € | ||
| 5mg | 178.00 € | ||
| 10mg | 278.00 € | ||
| 25mg | 513.00 € | ||
| 50mg | 768.00 € | ||
| 100mg | 1,154.00 € | ||
| 500mg | 2,249.00 € | ||
| 1mL*10mM (DMSO) | 186.00 € |
Estimated delivery in United States, on Tuesday 18 Feb 2025
SOS1-IN-16
CAS:2930763-85-0
SOS1-IN-16 (Comp 54) serves as a selective SOS1 inhibitor exhibiting an IC50 value of 7.2 …
Formula:
C30H31F3N4O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
552.59
Ref: TM-T79183
| 25mg | 1,688.00 € | ||
| 50mg | 2,225.00 € | ||
| 100mg | 2,897.00 € |
Estimated delivery in United States, on Tuesday 18 Feb 2025
KRAS G12C inhibitor 32
CAS:2756739-00-9
KRAS G12C Inhibitor 32, an eight-membered heterocyclic compound with nitrogen, acts as a potent inhibitor …
Formula:
C29H30Cl3FN6O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
635.94
Ref: TM-T72335
| 25mg | 1,549.00 € | ||
| 50mg | 2,038.00 € | ||
| 100mg | 2,617.00 € |
Estimated delivery in United States, on Tuesday 18 Feb 2025
SOS1/KRAS-IN-1
CAS:2836330-34-6
SOS1/KRAS-IN-1 (Compound 2) serves as an inhibitor of SOS1/KRAS, with potential application in the study …
Formula:
C24H26F3N5O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
457.49
Ref: TM-T79162
| 25mg | 1,827.00 € | ||
| 50mg | 2,412.00 € | ||
| 100mg | 3,178.00 € |
Estimated delivery in United States, on Tuesday 18 Feb 2025
JNK3 inhibitor-3
CAS:2873465-25-7
JNK3 Inhibitor-3 selectively blocks JNK3 (>4.1 nM), crosses the blood-brain barrier, is orally active, …
Formula:
C26H25N7O2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
467.52
Ref: TM-T72714
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Tuesday 18 Feb 2025
MEK-IN-6 hydrate
CAS:2845153-35-5
MEK-IN-6 hydrate (compound 69), a MEK inhibitor, exhibits an IC50 value of 2 nM in …
Formula:
C18H22FN3O5S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
411.45
Ref: TM-T79048
| 25mg | 1,549.00 € | ||
| 50mg | 2,038.00 € | ||
| 100mg | 2,617.00 € |
Estimated delivery in United States, on Tuesday 18 Feb 2025
MEK-IN-6
CAS:2845151-86-0
MEK-IN-6 (Example 69), a potent MEK inhibitor, effectively inhibits ERK1/2 (Thr202/Tyr204) phosphorylation in A375 cells, …
Formula:
C18H20FN3O4S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
393.43
Ref: TM-T79047
| 25mg | 1,549.00 € | ||
| 50mg | 2,038.00 € | ||
| 100mg | 2,617.00 € |
Estimated delivery in United States, on Tuesday 18 Feb 2025
Glecirasib
CAS:2657613-87-9
Glecirasib (KRAS G12C inhibitor 36) is a potent inhibitor targeting the oncogenic KRAS G12C mutation, …
Formula:
C31H26ClF4N7O2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
640.03
Ref: TM-T78651
| 25mg | 6,707.00 € | ||
| 50mg | 9,394.00 € | ||
| 100mg | 13,174.00 € |
Estimated delivery in United States, on Tuesday 18 Feb 2025
MS934
CAS:2756323-15-4
MS934, a novel VHL-recruiting MEK 1/2 degrader, exhibits potent anti-proliferative effects on HT-29 cell growth, …
Formula:
C52H69F3IN7O6S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
1104.11
Ref: TM-T79143
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 18 Feb 2025
PROTAC KRAS G12C degrader-3
CAS:2768099-51-8
PROTAC KRAS G12C Degrader-3 (Comp 283) serves as a potent degrader of KRAS G12C, utilized …
Formula:
C63H75ClN14O6
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
1159.81
Ref: TM-T79148
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 18 Feb 2025
pan-KRAS-IN-3
CAS:2875116-29-1
Pan-KRAS-IN-3 (Example 84) is a pan-KRAS inhibitor suitable for cancer research [1].
Formula:
C33H32F3N5O2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
587.63
Ref: TM-T79814
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 18 Feb 2025
KRAS G12C inhibitor 59
CAS:2914919-88-1
KRAS G12C Inhibitor 59 is a compound with anticancer properties.
Formula:
C32H39F6N7O5
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
715.69
Ref: TM-T79150
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 18 Feb 2025
RMC-4998
CAS:2642037-07-6
RMC-4998 is a molecular glue compound exhibiting potent antitumor activity, capable of forming a ternary …
Formula:
C57H74N8O7
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
983.25
Ref: TM-T79870
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 18 Feb 2025
Nedometinib
CAS:2252314-46-6
Nedometinib (NFX-179) is a MEK1 inhibitor with anticancer and antitumor activities, which can be used …
Formula:
C17H16FIN4O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
470.24
Ref: TM-T78209
| 1mg | 72.00 € | ||
| 5mg | 153.00 € | ||
| 10mg | 217.00 € | ||
| 25mg | 357.00 € | ||
| 50mg | 607.00 € | ||
| 100mg | 991.00 € |
Estimated delivery in United States, on Tuesday 18 Feb 2025
KRAS G12C inhibitor 17
CAS:2349393-04-8
KRAS G12C inhibitor 17 is a potent KRAS G12C inhibitor.
Formula:
C24H20ClF2N3O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
471.88
Ref: TM-T11771
| 25mg | 1,827.00 € | ||
| 50mg | 2,404.00 € | ||
| 100mg | 3,168.00 € |
Estimated delivery in United States, on Tuesday 18 Feb 2025
KRAS G12C inhibitor 5
CAS:2158297-63-1
KRAS G12C inhibitor 5 is a KRas G12C inhibitor.
Formula:
C32H37N7O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
551.68
Ref: TM-T11780
| 25mg | 1,967.00 € | ||
| 50mg | 2,598.00 € | ||
| 100mg | 3,458.00 € |
Estimated delivery in United States, on Tuesday 18 Feb 2025
MK-8353
CAS:1184173-73-6
MK-8353 (SCH900353) is a potent, selective and orally available inhibitor of ERK1/2 (IC50s of 23.0 …
Formula:
C37H41N9O3S
Purity:
96.15% - 99.89%
Color and Shape:
Solid
Molecular weight:
691.84
Ref: TM-T12069
| 1mg | 79.00 € | ||
| 5mg | 153.00 € | ||
| 10mg | 268.00 € | ||
| 25mg | 451.00 € | ||
| 50mg | 655.00 € | ||
| 100mg | 933.00 € | ||
| 1mL*10mM (DMSO) | 229.00 € |
Estimated delivery in United States, on Tuesday 4 Mar 2025
