MAPK

MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.

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Brand	Product data	Purity	Price range	Estimated delivery
	Pan-RAS-IN-1 REF: TM-T16432CAS: 1835283-94-7	98.57%	80.00 €~1,866.00 €	Tue 04 Mar 25
	J-104871 REF: TM-T24188CAS: 191088-19-4	98%	To inquire	Tue 18 Mar 25
	WQ-C-401 REF: TM-T200766CAS: 2376694-72-1	- - -	To inquire	Tue 18 Mar 25
	10-Methoxy-canthin-6-one REF: TM-T200611CAS: 86293-40-5	- - -	To inquire	Tue 18 Mar 25
	EBI-1051 REF: TM-T15193CAS: 1801896-05-8	98%	1,468.00 €~4,019.00 €	Tue 18 Mar 25
	RGT-018 REF: TM-T89897CAS: 2794934-49-7	- - -	To inquire	Tue 18 Mar 25
	DOR agonist 2 REF: TM-T200382CAS: 1212540-02-7	- - -	To inquire	Tue 18 Mar 25
	KRAS inhibitor-32 REF: TM-T200688CAS: 3056974-05-8	- - -	To inquire	Tue 18 Mar 25
	KU004 REF: TM-T89998CAS: 1260401-93-1	- - -	To inquire	Tue 18 Mar 25
	KRAS inhibitor-31 REF: TM-T200064CAS: 2920695-77-6	- - -	To inquire	Tue 18 Mar 25
	12(S)-HETE REF: TM-T37047CAS: 54397-83-0	- - -	404.00 €	Tue 18 Mar 25
	KRas G12C inhibitor 2 REF: TM-T11777CAS: 2206735-61-5	98%	1,558.00 €~4,289.00 €	Tue 18 Mar 25
	KRAS G12C inhibitor 15 REF: TM-T11769CAS: 2349393-21-9	98%	715.00 €~5,985.00 €	Tue 18 Mar 25
	PF-03715455 REF: TM-T16477CAS: 1056164-52-3	98%	2,523.00 €~4,654.00 €	Tue 18 Mar 25
	BMS-214662 REF: TM-T10567CAS: 195987-41-8	- - -	157.00 €~3,744.00 €	Tue 18 Mar 25
	KRAS inhibitor-34 REF: TM-T200670CAS: 3054800-66-4	- - -	To inquire	Tue 18 Mar 25
	pan-KRAS degrader 1 REF: TM-T200566CAS: 2937327-83-6	- - -	To inquire	Tue 18 Mar 25
	KRAS inhibitor-8 REF: TM-T11775CAS: 2022986-70-3	98%	1,374.00 €~3,739.00 €	Tue 18 Mar 25
	Ergosterol peroxide REF: TM-TMA1743CAS: 2061-64-5	98%	188.00 €~4,346.00 €	Tue 18 Mar 25
	ERK2 IN-1 REF: TM-T11228CAS: 1093061-47-2	98%	1,374.00 €~3,739.00 €	Tue 18 Mar 25

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Pan-RAS-IN-1

CAS:1835283-94-7

Pan-RAS-IN-1 is an inhibitor of pan-Ras. It disrupts the interaction of Ras proteins and their …

Formula:

C₃₆H₄₁Cl₂F₃N₆O₂

Purity:

98.57%

Color and Shape:

Solid

Molecular weight:

717.65

Ref: TM-T16432

1mg		80.00 €
2mg		96.00 €
5mg		144.00 €
10mg		215.00 €
25mg		437.00 €
50mg		655.00 €
100mg		931.00 €
500mg		1,866.00 €
1mL*10mM (DMSO)		220.00 €

Estimated delivery in United States, on Tuesday 4 Mar 2025

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J-104871

CAS:191088-19-4

J-104871 (UNII-6137X5QNJF) is an FTase inhibitor that inhibits tumor growth in nude mice transplanted with …

Formula:

C₃₈H₃₂N₂O₁₂

Purity:

98%

Color and Shape:

Solid

Molecular weight:

708.67

Ref: TM-T24188

1mg		182.00 €
5mg		450.00 €
10mg		644.00 €
25mg		1,005.00 €

Estimated delivery in United States, on Tuesday 18 Mar 2025

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WQ-C-401

CAS:2376694-72-1

WQ-C-401 is an orally active inhibitor of the platelet-derived growth factor receptor (PDGFR). It inhibits …

Formula:

C₂₄H₂₆N₄O₃

Color and Shape:

Liquid

Molecular weight:

418.49

Ref: TM-T200766

10mg		To inquire
50mg		To inquire

Estimated delivery in United States, on Tuesday 18 Mar 2025

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10-Methoxy-canthin-6-one

10-Methoxy-canthin-6-one

10-Methoxy-canthin-6-one (Mtx-C) acts as a DNA damage inducer that embeds into DNA, promoting cell cycle …

Formula:

C₁₅H₁₀N₂O₂

Color and Shape:

Liquid

Molecular weight:

250.25

Ref: TM-T200611

10mg		To inquire
50mg		To inquire

Estimated delivery in United States, on Tuesday 18 Mar 2025

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EBI-1051

CAS:1801896-05-8

EBI-1051 is a highly potent and orally efficacious inhibitor of MEK (IC50: 3.9 nM).

Formula:

C₁₈H₁₅F₂IN₂O₅

Purity:

98%

Color and Shape:

Solid

Molecular weight:

504.22

Ref: TM-T15193

25mg		2,245.00 €
50mg		2,972.00 €
100mg		4,019.00 €

Estimated delivery in United States, on Tuesday 18 Mar 2025

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RGT-018

CAS:2794934-49-7

RGT-018 is a potent oral SOS1 inhibitor with antitumor properties. It exerts its anticancer activity …

Formula:

C₂₇H₂₄F₃N₇O₂

Color and Shape:

Liquid

Molecular weight:

535.52

Ref: TM-T89897

10mg		To inquire
50mg		To inquire

Estimated delivery in United States, on Tuesday 18 Mar 2025

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DOR agonist 2

CAS:1212540-02-7

Compound 3 (DOR agonist 2) acts as a Delta Opioid Receptor agonist. It inhibits the …

Formula:

C₂₉H₂₆N₂O₃

Color and Shape:

Liquid

Molecular weight:

450.53

Ref: TM-T200382

10mg		To inquire
50mg		To inquire

Estimated delivery in United States, on Tuesday 18 Mar 2025

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KRAS inhibitor-32

KRAS inhibitor-32

CAS:3056974-05-8

KRAS inhibitor-32 (compound 139A) is a KRAS inhibitor utilized in cancer research.

Formula:

C₂₉H₃₅FN₁₀OS₂

Color and Shape:

Liquid

Molecular weight:

622.78

Ref: TM-T200688

10mg		To inquire
50mg		To inquire

Estimated delivery in United States, on Tuesday 18 Mar 2025

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KU004

CAS:1260401-93-1

KU004, a potent dual EGFR/HER2 inhibitor, exhibits anticancer properties. It inhibits the proliferation of human …

Formula:

C₂₉H₂₇ClFN₄O₂P

Color and Shape:

Liquid

Molecular weight:

548.98

Ref: TM-T89998

10mg		To inquire
50mg		To inquire

Estimated delivery in United States, on Tuesday 18 Mar 2025

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KRAS inhibitor-31

KRAS inhibitor-31

CAS:2920695-77-6

KRAS inhibitor-31 (compound 33), a potent agent targeting KRAS, exhibits K D (SPR) values of …

Formula:

C₃₃H₃₀F₃N₅O₄

Color and Shape:

Liquid

Molecular weight:

617.62

Ref: TM-T200064

10mg		To inquire
50mg		To inquire

Estimated delivery in United States, on Tuesday 18 Mar 2025

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12(S)-HETE

Enpatoran hydrochloride (M5049 hydrochloride) is a TLR7/8 inhibitor with antiviral activity that is used in …

Formula:

C₂₀H₃₂O₃

Color and Shape:

Liquid

Molecular weight:

320.47

Ref: TM-T37047

10µg 404.00 €

Estimated delivery in United States, on Tuesday 18 Mar 2025

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KRas G12C inhibitor 2

KRas G12C inhibitor 2

CAS:2206735-61-5

KRas G12C inhibitor 2 is a compound that inhibits KRas G12C.

Formula:

C₃₂H₃₇N₇O₃

Purity:

98%

Color and Shape:

Solid

Molecular weight:

567.68

Ref: TM-T11777

25mg		2,377.00 €
50mg		3,152.00 €
100mg		4,289.00 €

Estimated delivery in United States, on Tuesday 18 Mar 2025

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KRAS G12C inhibitor 15

KRAS G12C inhibitor 15

CAS:2349393-21-9

KRAS G12C inhibitor 15 is a potent KRAS G12C inhibitor .

Formula:

C₂₅H₂₁ClF₂N₄O₃

Purity:

98%

Color and Shape:

Solid

Molecular weight:

498.91

Ref: TM-T11769

25mg		2,941.00 €
50mg		3,872.00 €
100mg		5,985.00 €

Estimated delivery in United States, on Tuesday 18 Mar 2025

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PF-03715455

CAS:1056164-52-3

PF-03715455 is a potent p38 MAPK inhibitor, reducing TNFα in blood (IC50=1.7 nM) with selectivity …

Formula:

C₃₅H₃₄ClN₇O₃S₂

Purity:

98%

Color and Shape:

Solid

Molecular weight:

700.27

Ref: TM-T16477

5mg 4,654.00 €

Estimated delivery in United States, on Tuesday 18 Mar 2025

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BMS-214662

CAS:195987-41-8

BMS-214662: potent, selective farnesyl transferase inhibitor; triggers apoptosis in CML stem cells; antitumor effects.

Formula:

C₂₅H₂₃N₅O₂S₂

Color and Shape:

Solid

Molecular weight:

489.61

Ref: TM-T10567

25mg		2,106.00 €
50mg		2,789.00 €
100mg		3,744.00 €

Estimated delivery in United States, on Tuesday 18 Mar 2025

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KRAS inhibitor-34

KRAS inhibitor-34

CAS:3054800-66-4

KRAS inhibitor-34 (compound 27) is a KRAS inhibitor with an IC50 of 6.4 nM and …

Formula:

C₄₃H₄₁F₃N₆O₃

Color and Shape:

Liquid

Molecular weight:

746.82

Ref: TM-T200670

10mg		To inquire
50mg		To inquire

Estimated delivery in United States, on Tuesday 18 Mar 2025

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pan-KRAS degrader 1

pan-KRAS degrader 1

CAS:2937327-83-6

Pan-KRAS degrader 1 (Compound 1) is a broad-spectrum KRAS degrader, exhibiting an inhibitory constant Ki …

Formula:

C₂₂H₂₆N₈OS

Color and Shape:

Liquid

Molecular weight:

450.56

Ref: TM-T200566

10mg		To inquire
50mg		To inquire

Estimated delivery in United States, on Tuesday 18 Mar 2025

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KRAS inhibitor-8

KRAS inhibitor-8

CAS:2022986-70-3

KRAS inhibitor-8 is a potent KRAS G12C inhibitor.

Formula:

C₂₆H₂₄ClF₄N₅O₃

Purity:

98%

Color and Shape:

Solid

Molecular weight:

565.95

Ref: TM-T11775

25mg		2,106.00 €
50mg		2,785.00 €
100mg		3,739.00 €

Estimated delivery in United States, on Tuesday 18 Mar 2025

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Ergosterol peroxide

Ergosterol peroxide

Ergosterol peroxide inhibits osteoclasts, has antiviral/antitumor effects, stimulates Foxo3a, and may prevent renal fibrosis.

Formula:

C₂₈H₄₄O₃

Purity:

98%

Color and Shape:

Solid

Molecular weight:

428.65

Ref: TM-TMA1743

1mg		361.00 €
5mg		1,404.00 €
500µg		188.00 €

Estimated delivery in United States, on Tuesday 18 Mar 2025

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ERK2 IN-1

CAS:1093061-47-2

ERK2 IN-1 is a selective ERK2 inhibitor with an IC50 of 7 nM.

Formula:

C₃₆H₃₄FN₇O₂S

Purity:

98%

Color and Shape:

Solid

Molecular weight:

647.76

Ref: TM-T11228

25mg		2,106.00 €
50mg		2,785.00 €
100mg		3,739.00 €

Estimated delivery in United States, on Tuesday 18 Mar 2025

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