MAPK
MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.
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BRAF inhibitor
CAS:918505-61-0
BRAF inhibitor is an inhibitor of B-Raf.
Formula:
C22H18F2N4O3S
Purity:
97.95% - 98.27%
Color and Shape:
Solid
Molecular weight:
456.47
Ref: TM-T10599
| 1mg | 46.00 € | ||
| 5mg | 91.00 € | ||
| 10mg | 142.00 € | ||
| 25mg | 247.00 € | ||
| 50mg | 387.00 € | ||
| 100mg | 552.00 € | ||
| 200mg | 801.00 € | ||
| 1mL*10mM (DMSO) | 103.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
KB-5246
CAS:119474-55-4
KB-5246, displays antibacterial activities.is a tetracyclic quinolone.
Formula:
C18H17ClFN3O4S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
425.86
Ref: TM-T11744
| 25mg | 1,549.00 € | ||
| 50mg | 2,039.00 € | ||
| 100mg | 2,619.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
PERK-IN-3
CAS:1337532-08-7
PERK-IN-3 is a potent inhibitor of PERK(IC50 of 7.4 nM).
Formula:
C22H16F2N4O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
406.38
Ref: TM-T12410
| 25mg | 1,549.00 € | ||
| 50mg | 2,038.00 € | ||
| 100mg | 2,617.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
BI-2852
CAS:2375482-51-0
BI-2852: nanomolar affinity KRAS switch I/II pocket inhibitor; blocks signaling, halts KRAS mutant cell growth.
Formula:
C31H28N6O2
Purity:
98.98%
Color and Shape:
Solid
Molecular weight:
516.59
Ref: TM-T10533
| 1mg | 115.00 € | ||
| 5mg | 271.00 € | ||
| 10mg | 401.00 € | ||
| 25mg | 664.00 € | ||
| 50mg | 916.00 € | ||
| 100mg | 1,263.00 € | ||
| 1mL*10mM (DMSO) | 312.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
M443
CAS:1820684-31-8
M443 is a potent small molecule inhibitor of MRK that inhibits radiation-induced activation of p38 …
Formula:
C31H30F3N7O2
Purity:
98.95%
Color and Shape:
Solid
Molecular weight:
589.61
Ref: TM-T15943
| 1mg | 185.00 € | ||
| 1mL*10mM (DMSO) | 355.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
KRAS inhibitor-6
CAS:2022986-61-2
KRAS inhibitor-6 is a potent KRAS G12C inhibitor.
Formula:
C27H30ClF2N5O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
546.01
Ref: TM-T11773
| 25mg | 1,549.00 € | ||
| 50mg | 2,031.00 € | ||
| 100mg | 2,609.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
NMDAR/TRPM4-IN-2
CAS:2243506-33-2
Potent NMDAR/TRPM4-IN-2 blocks NMDAR/TRPM4, protects brain and retinal neurons, and prevents mitochondrial dysfunction with an …
Formula:
C11H19BrCl2N2
Purity:
98.77%
Color and Shape:
Odour Color
Molecular weight:
330.092
Ref: TM-T72662
| 5mg | 46.00 € | ||
| 10mg | 64.00 € | ||
| 25mg | 95.00 € | ||
| 50mg | 138.00 € | ||
| 100mg | 198.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
ARS-1323-alkyne
CAS:2436544-27-1
ARS-1323-alkyne is a switch-II pocket (S-IIP) inhibitor and a conformational specific chemical reporter of KRASG12C …
Formula:
C28H27ClF2N6O3
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
569
Ref: TM-T10374
| 1mg | 169.00 € | ||
| 5mg | 446.00 € | ||
| 10mg | 753.00 € | ||
| 25mg | 1,113.00 € | ||
| 50mg | 1,506.00 € | ||
| 100mg | 2,034.00 € |
Estimated delivery in United States, on Tuesday 18 Feb 2025
pan-KRAS-IN-4
CAS:2885961-55-5
Pan-KRAS-IN-4 (compound 5) is a potent KRAS inhibitor, demonstrating IC50 values of 0.37 nM for …
Formula:
C36H34F2N6O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
636.69
Ref: TM-T79799
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 18 Feb 2025
KRAS G12C inhibitor 58
CAS:2915599-52-7
KRAS G12C inhibitor 58 is utilized in cancer research as an inhibitor of the KRAS …
Formula:
C51H64ClF4N9O8S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
1074.62
Ref: TM-T79057
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 18 Feb 2025
KRAS G12C inhibitor 16
CAS:2349392-79-4
KRAS G12C inhibitor 16 is a potent KRAS G12C inhibitor.
Formula:
C24H21ClFN3O3
Purity:
100%
Color and Shape:
Solid
Molecular weight:
453.89
Ref: TM-T11770
| 1mg | 426.00 € | ||
| 2mg | 624.00 € | ||
| 5mg | 988.00 € | ||
| 10mg | 1,323.00 € | ||
| 25mg | 1,967.00 € | ||
| 50mg | 2,600.00 € |
Estimated delivery in United States, on Tuesday 18 Feb 2025
TH-Z827
CAS:2847881-81-4
TH-Z827 is a mutant-selective inhibitor targeting KRAS(G12D) with an IC50 of 2.4 μM, demonstrating specificity …
Formula:
C30H38N6O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
498.66
Ref: TM-T79092
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 18 Feb 2025
XRP44X
CAS:729605-21-4
XRP44X (XRP 44X) is a potent inhibitor of Ras-Net (Elk-3) pathway.
Formula:
C21H21ClN4O
Purity:
97.51%
Color and Shape:
Solid
Molecular weight:
380.87
Ref: TM-T20759
| 10mg | 54.00 € | ||
| 25mg | 79.00 € | ||
| 50mg | 109.00 € | ||
| 1mL*10mM (DMSO) | 56.00 € |
Estimated delivery in United States, on Tuesday 18 Feb 2025
Org OD 02-0
CAS:13258-85-0
10-Ethenyl-19-norprogesterone (Org OD 02-0) is a selective agonist for the membrane progesterone receptor α (mPRα) …
Formula:
C22H30O2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
326.47
Ref: TM-T81598
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 18 Feb 2025
B-Raf IN 15
CAS:832107-31-0
B-Raf IN 15 is a BRAF inhibitor that inhibits BRAFWT and BRAFV600E and can be …
Formula:
C19H15N3OS
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
333.41
Ref: TM-T78183
| 1mg | 56.00 € | ||
| 5mg | 119.00 € | ||
| 10mg | 185.00 € | ||
| 25mg | 323.00 € | ||
| 1mL*10mM (DMSO) | 136.00 € |
Estimated delivery in United States, on Tuesday 18 Feb 2025
KRAS G12C inhibitor 61
CAS:2300967-40-0
KRAS G12C inhibitor 61 (Example 3) demonstrates potent activity by inhibiting phospho-ERK 1/2 in MIA …
Formula:
C31H33ClFN7O2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
590.09
Ref: TM-T79808
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 18 Feb 2025
Laxiflorin B
CAS:165337-71-3
Laxiflorin B, a novel selective inhibitor of ERK 1/2 derived from herbal sources, exhibits antitumor …
Formula:
C20H24O5
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
344.4
Ref: TM-T79785
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 18 Feb 2025
p38 Kinase inhibitor 4
CAS:13142-47-7
Compound 135, also known as p38 Kinase Inhibitor 4, is a potent inhibitor of p38 …
Formula:
C12H9Cl2N3O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
282.13
Ref: TM-T79028
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 18 Feb 2025
KRas G12C inhibitor 1
CAS:2158297-28-8
KRas G12C inhibitor 1 is a compound that inhibits KRas G12C.
Formula:
C31H38N6O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
542.67
Ref: TM-T11776
| 25mg | 1,549.00 € | ||
| 50mg | 2,031.00 € | ||
| 100mg | 2,609.00 € |
Estimated delivery in United States, on Tuesday 18 Feb 2025
ARS-1323
CAS:1698024-73-5
ARS-1323 is the racemate of ARS-1620 and a mutant K-ras G12C inhibitor.
Formula:
C21H17ClF2N4O2
Purity:
98.88%
Color and Shape:
Solid
Molecular weight:
430.84
Ref: TM-T10375
| 1mg | 42.00 € | ||
| 5mg | 82.00 € | ||
| 10mg | 122.00 € | ||
| 25mg | 181.00 € | ||
| 50mg | 236.00 € | ||
| 100mg | 342.00 € | ||
| 1mL*10mM (DMSO) | 91.00 € |
Estimated delivery in United States, on Tuesday 18 Feb 2025
