MAPK
MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.
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AS601245.2TFA (345987-15-7 free base)
CAS:345987-16-8
AS601245.2TFA (345987-15-7 free base) (AS601245.2TFA) is a cell-permeable Inhibitor of JNK (IC50s of 150, 220, …
Formula:
C24H18F6N6O4S
Purity:
98%
Color and Shape:
Soild
Molecular weight:
600.50
Ref: TM-T8661
| 1mg | 57.00 € | ||
| 2mg | 81.00 € | ||
| 5mg | 100.00 € | ||
| 10mg | 178.00 € | ||
| 25mg | 376.00 € | ||
| 50mg | 550.00 € | ||
| 100mg | 799.00 € | ||
| 500mg | 1,624.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Isocryptotanshinone
CAS:22550-15-8
Isocryptotanshinone inhibits protein tyrosine phosphatase 1B (PTP1B) activity with 50% inhibitory concentration values of 56.1±6.3 …
Formula:
C19H20O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
296.36
Ref: TM-TN1775
| 5mg | 746.00 € | ||
| 1mL*10mM (DMSO) | 765.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
OVA-E1 peptide TFA
CAS:1262750-80-0
OVA-E1 peptide TFA activates the p38 and JNK cascades similarly in mutant and wild-type thymocytes.
Formula:
C49H77F3N10O16
Purity:
98%
Color and Shape:
Solid
Molecular weight:
1119.19
Ref: TM-T38665
| 1mg | 151.00 € | ||
| 5mg | 413.00 € | ||
| 10mg | 619.00 € | ||
| 25mg | 1,112.00 € | ||
| 50mg | 1,669.00 € | ||
| 100mg | 2,503.00 € | ||
| 200mg | 3,754.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
(S)-BAY-293
CAS:2244904-69-4
(S)-BAY-293 is a potent pan-KRAS inhibitor for the study of primary non-small lung and pancreatic …
Formula:
C25H28N4O2S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
448.58
Ref: TM-T41214
| 5mg | 660.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
ERK5-IN-6
CAS:2734916-64-2
ERK5-IN-6 is an ERK5 kinase inhibitor with antiproliferative, anticonvulsant, and antitumor activity for the study …
Formula:
C23H21N3
Purity:
98.59%
Color and Shape:
Soild
Molecular weight:
339.43
Ref: TM-T77731
| 1mg | 181.00 € | ||
| 5mg | 449.00 € | ||
| 10mg | 643.00 € | ||
| 25mg | 1,003.00 € | ||
| 50mg | 1,383.00 € | ||
| 100mg | 1,841.00 € | ||
| 500mg | 3,647.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Patritumab
CAS:1262787-83-6
Patritumab (U3-1287), an anti-HER3 antibody, may inhibit tumor growth and cancer cell division in non-small …
Purity:
95.2%
Color and Shape:
Liquid
Molecular weight:
146.97 kDa
Ref: TM-T76796
| 1mg | 279.00 € | ||
| 5mg | 739.00 € | ||
| 10mg | 1,153.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Ro-3201195
CAS:249937-52-8
Ro-3201195 is a novel orally available p38 MAPK inhibitor with high selectivity.
Formula:
C19H18FN3O4
Purity:
100%
Color and Shape:
Liquid
Molecular weight:
371.36
Ref: TM-T68134
| 1mg | 125.00 € | ||
| 5mg | 299.00 € | ||
| 10mg | 446.00 € | ||
| 25mg | 735.00 € | ||
| 50mg | 1,009.00 € | ||
| 100mg | 1,374.00 € | ||
| 500mg | 2,747.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Scio-323
CAS:309913-51-7
Scio-323 is an orally available p38 mitogen-activated protein (MAPK) kinase inhibitor.
Formula:
C27H30FN3O4
Purity:
100.00%
Color and Shape:
Liquid
Molecular weight:
479.54
Ref: TM-T68139
| 1mg | 182.00 € | ||
| 5mg | 399.00 € | ||
| 10mg | 595.00 € | ||
| 25mg | 917.00 € | ||
| 50mg | 1,262.00 € | ||
| 100mg | 1,698.00 € | ||
| 500mg | 3,418.00 € | ||
| 1mL*10mM (DMSO) | 488.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Shizukaol B
CAS:142279-40-1
Shizukaol B: anti-inflammatory, inhibits NO & JNK-AP-1 in LPS-microglia, low toxicity, anti-HIV, hampers monocyte-HUVEC adhesion.
Formula:
C40H44O13
Purity:
98%
Color and Shape:
Solid
Molecular weight:
732.77
Ref: TM-TN5011
| 1mg | 300.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Saponarin
CAS:20310-89-8
Saponarin (Petrocomoside) shows in vitro and in vivo hepatoprotective and antioxidant activity against CCl4-induced liver …
Formula:
C27H30O15
Purity:
98.84%
Color and Shape:
Solid
Molecular weight:
594.52
Ref: TM-TN2179
| 1mg | 78.00 € | ||
| 5mg | 184.00 € | ||
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 17 Dec 2024
MRTX0902
CAS:2654743-22-1
MRTX0902 is an effective and high selective inhibitor of SOS1 with an IC50 of 46 …
Formula:
C22H24N6O
Purity:
98.37%
Color and Shape:
Solid
Molecular weight:
388.47
Ref: TM-T9755
| 1mg | 94.00 € | ||
| 5mg | 199.00 € | ||
| 10mg | 292.00 € | ||
| 25mg | 618.00 € | ||
| 50mg | 989.00 € | ||
| 100mg | 1,613.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
CHPG hydrochloride
CHPG hydrochloride is a selective agonist of mGluR5.
Formula:
C8H9Cl2NO3
Purity:
98.1%
Color and Shape:
Soild
Molecular weight:
238.07
Ref: TM-T10809L
| 1mg | 92.00 € | ||
| 5mg | 183.00 € | ||
| 10mg | 274.00 € | ||
| 25mg | 439.00 € | ||
| 50mg | 624.00 € | ||
| 100mg | 830.00 € | ||
| 500mg | 1,643.00 € | ||
| 1mL*10mM (DMSO) | 167.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Laxiflorin B-4
Laxiflorin B-4, a derivative of Laxiflorin B, demonstrates increased affinity for ERK1/2 and enhanced tumor-suppressive …
Purity:
98%
Ref: TM-T81947
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Divarasib
CAS:2417987-45-0
Divarasib (GDC-6036), an investigational KRAS G12C inhibitor for solid tumors, has an IC50 of <0.01 …
Formula:
C29H32ClF4N7O2
Purity:
98.79%
Color and Shape:
Liquid
Molecular weight:
622.06
Ref: TM-T9972
| 1mg | 228.00 € | ||
| 5mg | 571.00 € | ||
| 10mg | 810.00 € | ||
| 25mg | 1,233.00 € | ||
| 50mg | 1,653.00 € | ||
| 100mg | 2,209.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
ADT-007
CAS:1945941-09-2
ADT-007 is a pan-RAS inhibitor with potent anticancer activity.
Formula:
C26H24FNO5
Purity:
97.75%
Color and Shape:
Soild
Molecular weight:
449.47
Ref: TM-T85316
| 1mg | 49.00 € | ||
| 5mg | 90.00 € | ||
| 10mg | 129.00 € | ||
| 25mg | 209.00 € | ||
| 50mg | 366.00 € | ||
| 100mg | 624.00 € | ||
| 500mg | 2,359.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Samidin
CAS:477-33-8
Samidin has anti-inflammatory properties through suppression of NF-κB and AP-1-mediated-genes in lipopolysaccharide (LPS)-stimulated RAW 264.7 …
Formula:
C21H22O7
Purity:
98%
Color and Shape:
Solid
Molecular weight:
386.4
Ref: TM-TN4938
| 5mg | 453.00 € | ||
| 1mL*10mM (DMSO) | 463.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Cimiside E
CAS:154822-57-8
Cimiside E tamps inflammation, halts gastric cancer growth, and triggers cell death by modulating PPAR-γ, …
Formula:
C35H54O8
Purity:
98%
Color and Shape:
Solid
Molecular weight:
602.809
Ref: TM-TN3655
| 1mg | To inquire | ||
| 5mg | To inquire |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Corylifol C
CAS:775351-91-2
Corylifol C and, to a lesser extent, xanthoangelol are potent protein kinase inhibitors (inhibitory concentration …
Formula:
C20H18O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
338.35
Ref: TM-TN3711
| 5mg | 623.00 € | ||
| 1mL*10mM (DMSO) | 633.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
QL-X-138 HCl
QL-X-138 HCl is a BTK/MNK dual kinase inhibitor with anticancer activity and anti-dengue virus 2 …
Formula:
C25H20ClN5O2
Purity:
98.89%
Color and Shape:
Soild
Molecular weight:
457.91
Ref: TM-T38960L
| 1mg | 181.00 € | ||
| 5mg | 447.00 € | ||
| 10mg | 640.00 € | ||
| 25mg | 998.00 € | ||
| 50mg | 1,377.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Allicin
CAS:539-86-6
Allicin exerts antioxidant, bactericidal, anti-cancer, anti-inflammatory activities, it exerts an inhibitory immunomodulatory effect on intestinal …
Formula:
C6H10OS2
Purity:
≥98%
Color and Shape:
Clear To Slightly Yellow Liquid
Molecular weight:
162.27
Ref: TM-T3123
| 1g | 276.00 € | ||
| 25mg | 47.00 € | ||
| 50mg | 60.00 € | ||
| 100mg | 91.00 € | ||
| 500mg | 184.00 € | ||
| 1mL*10mM (DMSO) | 65.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
