MAPK
MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.
Read more
Saponarin
CAS:20310-89-8
Saponarin (Petrocomoside) shows in vitro and in vivo hepatoprotective and antioxidant activity against CCl4-induced liver …
Formula:
C27H30O15
Purity:
98.84%
Color and Shape:
Solid
Molecular weight:
594.52
Ref: TM-TN2179
| 1mg | 79.00 € | ||
| 5mg | 187.00 € | ||
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 16 Apr 2025
Laxiflorin B-4
Laxiflorin B-4, a derivative of Laxiflorin B, demonstrates increased affinity for ERK1/2 and enhanced tumor-suppressive …
Purity:
98%
Ref: TM-T81947
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 16 Apr 2025
Isocryptotanshinone
CAS:22550-15-8
Isocryptotanshinone inhibits protein tyrosine phosphatase 1B (PTP1B) activity with 50% inhibitory concentration values of 56.1±6.3 …
Formula:
C19H20O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
296.36
Ref: TM-TN1775
| 5mg | 750.00 € | ||
| 1mL*10mM (DMSO) | 770.00 € |
Estimated delivery in United States, on Wednesday 16 Apr 2025
Divarasib
CAS:2417987-45-0
Divarasib (GDC-6036), an investigational KRAS G12C inhibitor for solid tumors, has an IC50 of <0.01 …
Formula:
C29H32ClF4N7O2
Purity:
98.79%
Color and Shape:
Liquid
Molecular weight:
622.06
Ref: TM-T9972
| 1mg | 233.00 € | ||
| 5mg | 582.00 € | ||
| 10mg | 825.00 € | ||
| 25mg | 1,254.00 € | ||
| 50mg | 1,691.00 € | ||
| 100mg | 2,262.00 € |
Estimated delivery in United States, on Wednesday 16 Apr 2025
ADT-007
CAS:1945941-09-2
ADT-007 is a pan-RAS inhibitor with potent anticancer activity.
Formula:
C26H24FNO5
Purity:
97.75%
Color and Shape:
Soild
Molecular weight:
449.47
Ref: TM-T85316
| 1mg | 49.00 € | ||
| 5mg | 92.00 € | ||
| 10mg | 131.00 € | ||
| 25mg | 212.00 € | ||
| 50mg | 373.00 € | ||
| 100mg | 635.00 € | ||
| 500mg | 2,403.00 € |
Estimated delivery in United States, on Wednesday 16 Apr 2025
Corylifol C
CAS:775351-91-2
Corylifol C and, to a lesser extent, xanthoangelol are potent protein kinase inhibitors (inhibitory concentration …
Formula:
C20H18O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
338.35
Ref: TM-TN3711
| 5mg | 1,803.00 € | ||
| 1mL*10mM (DMSO) | 1,985.00 € |
Estimated delivery in United States, on Wednesday 16 Apr 2025
OVA-E1 peptide TFA
CAS:1262750-80-0
OVA-E1 peptide TFA activates the p38 and JNK cascades similarly in mutant and wild-type thymocytes.
Formula:
C49H77F3N10O16
Purity:
98%
Color and Shape:
Solid
Molecular weight:
1119.19
Ref: TM-T38665
| 1mg | 152.00 € | ||
| 5mg | 415.00 € | ||
| 10mg | 622.00 € | ||
| 25mg | 1,119.00 € | ||
| 50mg | 1,679.00 € | ||
| 100mg | 2,520.00 € | ||
| 200mg | 3,780.00 € |
Estimated delivery in United States, on Wednesday 16 Apr 2025
Cimiside E
CAS:154822-57-8
Cimiside E tamps inflammation, halts gastric cancer growth, and triggers cell death by modulating PPAR-γ, …
Formula:
C35H54O8
Purity:
98%
Color and Shape:
Solid
Molecular weight:
602.809
Ref: TM-TN3655
| 1mg | To inquire | ||
| 5mg | To inquire |
Estimated delivery in United States, on Wednesday 16 Apr 2025
Ro-3201195
CAS:249937-52-8
Ro-3201195 is a novel orally available p38 MAPK inhibitor with high selectivity.
Formula:
C19H18FN3O4
Purity:
100%
Color and Shape:
Liquid
Molecular weight:
371.36
Ref: TM-T68134
| 1mg | 128.00 € | ||
| 5mg | 304.00 € | ||
| 10mg | 457.00 € | ||
| 25mg | 747.00 € | ||
| 50mg | 1,026.00 € | ||
| 100mg | 1,406.00 € | ||
| 500mg | 2,812.00 € |
Estimated delivery in United States, on Wednesday 16 Apr 2025
Allicin
CAS:539-86-6
Allicin exerts antioxidant, bactericidal, anti-cancer, anti-inflammatory activities, it exerts an inhibitory immunomodulatory effect on intestinal …
Formula:
C6H10OS2
Purity:
≥98%
Color and Shape:
Clear To Slightly Yellow Liquid
Molecular weight:
162.27
Ref: TM-T3123
| 1g | 283.00 € | ||
| 25mg | 48.00 € | ||
| 50mg | 62.00 € | ||
| 100mg | 93.00 € | ||
| 500mg | 188.00 € | ||
| 1mL*10mM (DMSO) | 65.00 € |
Estimated delivery in United States, on Wednesday 16 Apr 2025
Bakkenolide IIIa
CAS:915289-60-0
Bakkenolide IIIa has antioxidant, and neuroprotective effects, it protects against cerebral damage by inhibiting AKT …
Formula:
C24H32O6S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
448.57
Ref: TM-TN3486
| 5mg | 703.00 € | ||
| 1mL*10mM (DMSO) | 712.00 € |
Estimated delivery in United States, on Wednesday 16 Apr 2025
Vem-L-Cy5
Vem-L-Cy5 (compound 3), a Vemurafenib-based BRAF inhibitor conjugated with the near-infrared (NIR) fluorophore cyanine-5 (Cy5), …
Formula:
C63H68F5N7O9S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
1194.31
Ref: TM-T78777
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 16 Apr 2025
Isorhamnetin 3-O-galactoside
CAS:6743-92-6
Isorhamnetin 3-O-galactoside shows antioxidant, anti-inflammatory, neuroprotective,and barrier protective activities, it could be used as a …
Formula:
C22H22O12
Purity:
98%
Color and Shape:
Solid
Molecular weight:
478.4
Ref: TM-TN1793
| 10mg | To inquire | ||
| 1ml*10 (DMSO) | To inquire |
Estimated delivery in United States, on Wednesday 16 Apr 2025
Akt/NF-κB/MAPK-IN-1
Akt/NF-κB/MAPK-IN-1 (compound 2m) serves as a potent, orally active inhibitor targeting NO with an IC50 …
Formula:
C38H56N2O4
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
604.86
Ref: TM-T78838
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 16 Apr 2025
Scio-323
CAS:309913-51-7
Scio-323是一种可口服的 p38丝裂原活化蛋白(MAPK)激酶抑制剂。
Formula:
C27H30FN3O4
Purity:
100.00%
Color and Shape:
Liquid
Molecular weight:
479.54
Ref: TM-T68139
| 1mg | 115.00 € | ||
| 5mg | 245.00 € | ||
| 10mg | 363.00 € | ||
| 25mg | 562.00 € | ||
| 50mg | 775.00 € | ||
| 100mg | 1,035.00 € | ||
| 200mg | 1,406.00 € | ||
| 1mL*10mM (DMSO) | 294.00 € |
Estimated delivery in United States, on Wednesday 16 Apr 2025
Cyclorasin 9A5 TFA
Cyclorasin 9A5 TFA is a cell-penetrating cyclic peptide consisting of 11 residues that inhibits the …
Formula:
C75H108FN25O13·xC2HF3O2
Color and Shape:
Liquid
Molecular weight:
1586.82 (free base)
Ref: TM-TP2915
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 16 Apr 2025
MEK ligand-2
CAS:212631-56-6
MEK ligand-2, a ligand for the target protein for PROTAC (Ligand for Target Protein for …
Formula:
C13H8F3IN2O2
Color and Shape:
Liquid
Molecular weight:
408.12
Ref: TM-T201410
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 16 Apr 2025
QL-X-138 HCl
QL-X-138 HCl is a BTK/MNK dual kinase inhibitor with anticancer activity and anti-dengue virus 2 …
Formula:
C25H20ClN5O2
Purity:
98.89%
Color and Shape:
Soild
Molecular weight:
457.91
Ref: TM-T38960L
| 1mg | 185.00 € | ||
| 5mg | 459.00 € | ||
| 10mg | 657.00 € | ||
| 25mg | 1,026.00 € | ||
| 50mg | 1,415.00 € |
Estimated delivery in United States, on Wednesday 16 Apr 2025
ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid
CAS:57719-81-0
Ent-11alpha-Hydroxy-15-oxokaur-16-en-19-oic acid has anti-cancer activity, it induces apoptosis of human malignant cancer cells, it also …
Formula:
C20H28O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
332.44
Ref: TM-TN3931
| 5mg | 513.00 € | ||
| 1mL*10mM (DMSO) | 522.00 € |
Estimated delivery in United States, on Wednesday 16 Apr 2025
MC 976
CAS:129831-99-8
MC 976 is a derivative of Vitamin D3.
Formula:
C27H42O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
414.63
Ref: TM-T16023
| 1mg | 1,045.00 € | ||
| 25mg | To inquire | ||
| 50mg | To inquire | ||
| 100mg | To inquire |
Estimated delivery in United States, on Wednesday 16 Apr 2025
