ERK
ERK is a key protein in the MAPK (Mitogen-Activated Protein Kinase) signaling pathway, which is involved in transmitting signals from cell surface receptors to the DNA in the cell nucleus. ERK plays a crucial role in the regulation of various cellular processes, including proliferation, differentiation, and survival. Dysregulation of ERK signaling is associated with the development of cancer and other diseases, making it an important target for therapeutic intervention. At CymitQuimica, we offer a selection of high-quality ERK inhibitors and modulators to support your research in cell signaling, oncology, and therapeutic development.
Found 193 products of "ERK"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
ERK5-IN-5
CAS:<p>ERK5-IN-5 is extracellular signal-regulated kinase 5 (ERK5) inhibitor with anticancer activity anticonvulsant activity inhibits A549 cell proliferation.</p>Formula:C19H16ClN3OPurity:99.77%Color and Shape:SoildMolecular weight:337.8AX-15836
CAS:<p>AX-15836 is an inhibitor of ERK5 (IC50 : 8 nM).</p>Formula:C32H40N8O5SPurity:98.96%Color and Shape:SolidMolecular weight:648.78MK2-IN-3 hydrate
CAS:<p>MK2-IN-3 hydrate (MK-2 Inhibitor III) is an orally active, selective, and ATP-competitive inhibitor of MAPKAP-K2 (MK-2) (IC50 of 0.85 nM)</p>Formula:C21H18N4O2Purity:99.58%Color and Shape:SolidMolecular weight:358.39Lidocaine
CAS:<p>Lidocaine, an amide local anesthetic, reduces pain and inflammation by dampening ICAM-1, cytokines, and neutrophil influx.</p>Formula:C14H22N2OPurity:99.95% - >99.99%Color and Shape:Needles From Benzene Or Alcohol SolidMolecular weight:234.34(E/Z)-BCI
CAS:<p>(E/Z)-BCI (NSC-150117), a dual-specificity phosphatase 6 (DUSP6) inhibitor with anti-inflammatory properties, reduces LPS-induced inflammatory mediators and ROS</p>Formula:C22H23NOPurity:99.94%Color and Shape:SolidMolecular weight:317.42Mefloquine
CAS:<p>Mefloquine (Ro 215998), a quinoline antimalarial agent, is an anti-SARS-CoV-2 entry inhibitor.</p>Formula:C17H16F6N2OPurity:99.89%Color and Shape:SolidMolecular weight:378.31Lidocaine Hydrochloride hydrate
CAS:<p>Lidocaine Hydrochloride hydrate is an amide local anesthetic, has anti-inflammatory property.</p>Formula:C14H22N2O·HCl·H2OPurity:99.95%Color and Shape:SolidMolecular weight:288.82LUT014
CAS:<p>LUT014 is a B-Raf inhibitor (IC50: 11.7 nM) and developed to decrease dose-limiting acneiform lesions associated with EGFR Inhibitors treatment.</p>Formula:C27H19F3N8OPurity:99.03%Color and Shape:SolidMolecular weight:528.49Methylthiouracil
CAS:<p>Methylthiouracil (NSC-193526) is a thiourea antithyroid agent that inhibits the synthesis of thyroid hormone, and it is used to treat hyperthyroidism.</p>Formula:C5H6N2OSPurity:99.89% - >99.99%Color and Shape:Crystals Saturated Aqueous Solution Is Neutral Or Slightly Acidic (Ntp 1992)Molecular weight:142.18Mefloquine hydrochloride
CAS:<p>Mefloquine hydrochloride (Mefloquin hydrochloride) is a quinoline derivative used for the prevention and therapy of P. falciparum malaria.</p>Formula:C17H17ClF6N2OPurity:99% - 99.74%Color and Shape:Off-White To Yellow SolidMolecular weight:414.77Lidocaine hydrochloride
CAS:<p>Lidocaine HCl: local anesthetic, antiarrhythmic, stronger & longer-lasting than procaine but shorter than bupivacaine/prilocaine.</p>Formula:C14H23ClN2OPurity:99.81% - 99.92%Color and Shape:White Crystal PowderMolecular weight:270.798MRTX-1257
CAS:<p>MRTX-1257: selective, irreversible KRAS G12C inhibitor; IC50 of 900 pM; 31% bioavailable in mice; 77% target engagement.</p>Formula:C33H39N7O2Purity:97.3% - 99.07%Color and Shape:SolidMolecular weight:565.71ERK5-IN-6
CAS:<p>ERK5-IN-6 is an ERK5 kinase inhibitor with antiproliferative, anticonvulsant, and antitumor activity for the study of central nervous system related diseases.</p>Formula:C23H21N3Purity:98.59%Color and Shape:SoildMolecular weight:339.43CC-90003
CAS:<p>CC-90003 is a selective inhibitor of ERK 1/2. It has antitumor activity.</p>Formula:C22H21F3N6O2Purity:99.42%Color and Shape:SolidMolecular weight:458.44Honokiol
CAS:<p>Honokiol (NSC-293100) is the active principle of magnolia extract. It inhibits the activation of Akt and enhances the phosphorylation of ERK1/ERK2.</p>Formula:C18H18O2Purity:99.65% - 99.94%Color and Shape:Dark Brown To White Fine Powder With Pleasant Odor Spicy And Slightly Bitter TasteMolecular weight:266.33Urolithin B
CAS:<p>Urolithin B is one of the gut microbial metabolites of ellagitannins and is found in diverse plant foods, including pomegranates, berries, walnuts, tropical</p>Formula:C13H8O3Purity:99.45%Color and Shape:SolidMolecular weight:212.24′-Demethylnobiletin
CAS:<p>4′-Demethylnobiletin, a bioactive metabolite, activates the PKA/ERK/CREB signaling pathway, enhances CRE-mediated transcription in hippocampal neurons, and</p>Formula:C20H20O8Color and Shape:SolidMolecular weight:388.37Anti-inflammatory agent 31
<p>Andrographolide derivative 31 is an anti-inflammatory that blocks NF-κB, PI3K/Akt, and ERK1/2 MAPK, and restores GSH levels to protect the liver.</p>Formula:C19H30O3Color and Shape:SolidMolecular weight:306.44Edaxeterkib
CAS:<p>Edaxeterkib is a potent extracellular signal- regulated kinase (ERK) inhibitor for the research of cancer.</p>Formula:C26H27N7O2Color and Shape:SolidMolecular weight:469.549LC-SF-14
<p>LC-SF-14 is a selective dual inhibitor of SHP2 and FGFR, with IC50 values of 71.6 nM and 8.9 nM, respectively. It blocks FGFR2-FRS2α-SHP2-MAPK signaling and ERK phosphorylation, and also inhibits the proliferation of KATOIII cancer cells (IC50: 9.2 nM). Furthermore, LC-SF-14 exhibits antitumor activity in SNU-16 xenograft mouse models, making it suitable for research on FGFR2-driven gastric cancer.</p>Formula:C44H50Cl3N13O5SColor and Shape:SolidMolecular weight:977.28442
