ERK
ERK is a key protein in the MAPK (Mitogen-Activated Protein Kinase) signaling pathway, which is involved in transmitting signals from cell surface receptors to the DNA in the cell nucleus. ERK plays a crucial role in the regulation of various cellular processes, including proliferation, differentiation, and survival. Dysregulation of ERK signaling is associated with the development of cancer and other diseases, making it an important target for therapeutic intervention. At CymitQuimica, we offer a selection of high-quality ERK inhibitors and modulators to support your research in cell signaling, oncology, and therapeutic development.
Found 217 products of "ERK"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Aurothiomalate sodium
CAS:Sodium aurothiomalate (Miochrysin) inhibits PKC-ι, TrxR; used as an anti-rheumatic and has anti-tumor properties.Formula:C4H3AuNa2O4SPurity:99.66%Color and Shape:SoildMolecular weight:390.07SC99
CAS:SC99 inhibits JAK2-STAT3, reducing STAT3 genes, platelet activity, and has anti-myeloma, anti-thrombotic effects.Formula:C15H8Cl2FN3OPurity:99.56%Color and Shape:SolidMolecular weight:336.15Ref: TM-T8719
1mg43.00€5mg87.00€1mL*10mM (DMSO)94.00€10mg133.00€25mg227.00€50mg344.00€100mg429.00€200mg597.00€Avatrombopag maleate
CAS:Avatrombopag (AKR-501/E5501) is an oral TPO receptor agonist for thrombocytopenia treatment, approved in 2018.Formula:C33H38Cl2N6O7S2Color and Shape:SolidMolecular weight:765.72DMU-212
CAS:DMU-212, a Resveratrol derivative, has antimitotic, antiproliferative, antioxidant properties; induces apoptosis via ERK1/2.Formula:C18H20O4Purity:99.86%Color and Shape:SolidMolecular weight:300.35Ref: TM-T36674
2mg34.00€5mg50.00€1mL*10mM (DMSO)56.00€10mg84.00€25mg152.00€50mg259.00€100mg385.00€500mg873.00€Periplocin
CAS:Periplocin fights lung cancer, induces apoptosis, stunts growth via beta-catenin/Tcf, and treats rheumatoid arthritis/traditional ailments.Formula:C36H56O13Purity:99.66% - 99.74%Color and Shape:SolidMolecular weight:696.82Ref: TM-T5S1982
1mg35.00€5mg77.00€10mg106.00€1mL*10mM (DMSO)107.00€25mg170.00€50mg253.00€100mg375.00€500mg892.00€SUN11602
CAS:SUN11602, an aniline compound, mimics the neuroprotective mechanisms of basic fibroblast growth factor.Formula:C26H37N5O2Purity:99.36%Color and Shape:SolidMolecular weight:451.6Corynoxeine
CAS:Corynoxeine inhibits ERK1/2, curbs VSMC growth induced by PDGF-BB, and may prevent vascular diseases and restenosis post-angioplasty.Formula:C22H26N2O4Purity:98.61% - 99.94%Color and Shape:SolidMolecular weight:382.45Theliatinib
CAS:Theliatinib: potent, selective EGFR inhibitor, anti-tumor; Ki=0.05 nM (EGFR), IC50=3 nM (EGFR), 22 nM (T790M/L858R).Formula:C25H26N6O2Purity:99.67%Color and Shape:SolidMolecular weight:442.51SCH772984
CAS:SCH772984 is an ERK inhibitor and is highly selective and ATP-competitive. SCH772984 exhibits antitumor activity. Cost-effective and quality-assured.
Formula:C33H33N9O2Purity:97.565% - 98.75%Color and Shape:SolidMolecular weight:587.67Ref: TM-T6066
1mg52.00€2mg77.00€5mg99.00€10mg148.00€25mg291.00€50mg437.00€100mg642.00€200mg914.00€500mg1,359.00€RU-301
CAS:RU-301 is a novel pan-tam inhibitorFormula:C21H19F3N4O4SPurity:98.87%Color and Shape:SolidMolecular weight:480.46Ref: TM-T7425
1mg98.00€5mg222.00€1mL*10mM (DMSO)241.00€10mg344.00€25mg587.00€50mg803.00€100mg1,063.00€ERK-IN-3
CAS:ERK-IN-3 (ASN007 free base) is a potent and orally active inhibitor of ERK.Formula:C22H25ClFN7O2Purity:99.55% - 99.76%Color and Shape:SolidMolecular weight:473.93TBHQ
CAS:TBHQ (tert-Butylhydroquinone) is an antioxidant that induces an antioxidant response through the redox-sensitive transcription factor Nrf2.Formula:C10H14O2Purity:99.17% - 99.53%Color and Shape:White Solid PowderMolecular weight:166.22Piperlongumine
CAS:Piperlongumine (Piplartine) is a natural alkaloid from Piper longum L.Formula:C17H19NO5Purity:97.03% - 99.90%Color and Shape:SolidMolecular weight:317.34Milnacipran
CAS:Milnacipran, an SNRI with 85% bioavailability, treats fibromyalgia and is well absorbed orally.Formula:C15H22N2OColor and Shape:SolidMolecular weight:246.35Methylnissolin
CAS:Methylnissolin (3-Hydroxy-9,10-dimethoxyptercarpan) is derived from Astragalus and has antibacterial and anti-cancer effects.Formula:C17H16O5Purity:99.68% - 99.98%Color and Shape:SolidMolecular weight:300.31SHP099
CAS:SHP099 (SHP099 free base) free base is an effective, selective, orally bioavailable, and efficacious SHP2 inhibitor (IC50 =0.07 μM and p-ERK modulation in cellsFormula:C16H19Cl2N5Purity:98.73% - 99.4%Color and Shape:SolidMolecular weight:352.26Ref: TM-T3564
1mg34.00€2mg49.00€1mL*10mM (DMSO)57.00€5mg74.00€10mg94.00€25mg165.00€50mg213.00€100mg388.00€PD98059
CAS:PD98059 is an MEK inhibitor that inhibits MEK1 and MEK2 (IC50=2/50 μM) and is non-ATP-competitive.Formula:C16H13NO3Purity:98.63% - >99.99%Color and Shape:Yellow SolidMolecular weight:267.28Ref: TM-T2623
5mg38.00€10mg50.00€1mL*10mM (DMSO)55.00€25mg78.00€50mg101.00€100mg168.00€200mg250.00€500mg421.00€EF24
CAS:EF24 treatment boosts caspase 3/9 activity, hinders MEK1/ERK phosphorylation, and exhibits strong anti-tumor effects in OSCC by deactivating MAPK/ERK.Formula:C19H15F2NOPurity:99.71%Color and Shape:SolidMolecular weight:311.33Ref: TM-T27242
1mg38.00€5mg80.00€1mL*10mM (DMSO)88.00€10mg126.00€25mg222.00€50mg334.00€100mg505.00€500mg1,071.00€1g1,431.00€BIX02189
CAS:BIX 02189 is a potent and selective inhibitor of MEK5 and ERK5(IC50 : 1.5 nM and 59 nM).Formula:C27H28N4O2Purity:97.84%Color and Shape:SolidMolecular weight:440.54Ref: TM-T21295
2mg33.00€5mg52.00€1mL*10mM (DMSO)55.00€10mg71.00€25mg119.00€50mg198.00€100mg296.00€200mg427.00€SEW2871
CAS:SEW 2871 is an orally available, highly selective S1P1 agonist. It activates ERK, Akt and Rac signaling pathways and induces S1P1 internalization and recycling.Formula:C20H10F6N2OSPurity:99.96%Color and Shape:White SolidMolecular weight:440.36
