ERK
ERK is a key protein in the MAPK (Mitogen-Activated Protein Kinase) signaling pathway, which is involved in transmitting signals from cell surface receptors to the DNA in the cell nucleus. ERK plays a crucial role in the regulation of various cellular processes, including proliferation, differentiation, and survival. Dysregulation of ERK signaling is associated with the development of cancer and other diseases, making it an important target for therapeutic intervention. At CymitQuimica, we offer a selection of high-quality ERK inhibitors and modulators to support your research in cell signaling, oncology, and therapeutic development.
Found 193 products of "ERK"
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ERK5-IN-1
CAS:<p>ERK5-IN-1 is a potent ERK5 inhibitor (IC50: 87 nM). It also inhibits LRRK2[G2019S] (IC50: 26 nM).</p>Formula:C25H29N7O2Purity:97.70%Color and Shape:SolidMolecular weight:459.54Tauroursodeoxycholate
CAS:<p>Tauroursodeoxycholate (UR 906), a hydrophilic bile acid, low in humans, may treat PBC, insulin resistance, and ALS.</p>Formula:C26H45NO6SPurity:98.77% - 99.93%Color and Shape:White SolidMolecular weight:499.7Loureirin B
CAS:<p>Loureirin B suppresses fibrosis by modulating MMPs/TIMPs, hindering fibroblast growth, and targeting TGF-β1/Smad2/3 pathway.</p>Formula:C18H20O5Purity:99.33% - 99.86%Color and Shape:SolidMolecular weight:316.35UNC569
CAS:<p>UNC569 selectively inhibits kidney URAT1, regulating uric acid excretion and aiding gout patient's uric balance.</p>Formula:C22H29FN6Purity:98.91% - 99.67%Color and Shape:SolidMolecular weight:396.5DEL-22379
CAS:<p>DEL-22379 is a water-soluble ERK dimerization inhibitor with IC50 of ～0.5 μM.</p>Formula:C26H28N4O3Purity:99.3% - 99.53%Color and Shape:SolidMolecular weight:444.532,5-Dihydroxyacetophenone
CAS:<p>2,5-Dihydroxyacetophenone has anti-anxiety, neuroprotective, anti-inflammatory properties, and modulates cell signaling and melanogenesis.</p>Formula:C8H8O3Purity:99.75%Color and Shape:Yellow PowderMolecular weight:152.15Butein
CAS:<p>Butein is a cAMP-specific PDE inhibitor, protein tyrosine kinase inhibitor, and SIRT1 activator.Cost-effective and quality-assured.</p>Formula:C15H12O5Purity:98.76% - >99.99%Color and Shape:SolidMolecular weight:272.25Pachymic acid
CAS:<p>Pachymic acid (3-O-Acetyltumulosic acid) is a natural product, and inhibits Akt and ERK signaling pathways.</p>Formula:C33H52O5Purity:99.43% - >99.99%Color and Shape:White PowderMolecular weight:528.76β-Neoendorphin acetate(77739-21-0 free base)
CAS:<p>beta-Neoendorphin acetate is an agonist of κ-opioid receptor</p>Formula:C56H81N13O14Purity:99.91%Color and Shape:SolidMolecular weight:1160.34GRK5-IN-2
CAS:<p>GRK5-IN-2, a pyridine-based bicyclic compound, is a potent G-protein-coupled receptor kinase 5 (GRK5) inhibitor.</p>Formula:C20H20N4O4Purity:99.92%Color and Shape:SolidMolecular weight:380.46-OAU
CAS:<p>6-OAU is a GPR84 agonist, activates it in HEK293 cells with a 105 nM EC50.</p>Formula:C12H21N3O2Purity:98.14% - 99.01%Color and Shape:SolidMolecular weight:239.31Nitidine chloride
CAS:<p>1.</p>Formula:C21H18ClNO4Purity:96.59% - 98.91%Color and Shape:SolidMolecular weight:383.82XMD17-109
CAS:<p>XMD17-109 (ERK5-IN-1) is a new selective ERK-5 inhibitor (EC50: 4.2 uM, HEK293 cells).</p>Formula:C36H46N8O3Purity:98.75% - 99.7%Color and Shape:SolidMolecular weight:638.8A-674563 2HCl(552325-73-2(fb-2hcl))
<p>A-674563 2HCl is an Akt1 inhibitor with Ki of 11 nM, modest potent to PKA and >30-fold selective for Akt1 over PKC.</p>Formula:C22H24Cl2N4OPurity:94.66%Color and Shape:SolidMolecular weight:431.36DCLK1-IN-1
CAS:<p>DCLK1-IN-1 is a selective, in vivo compatible chemical probe of the kinase domain of doublecortin-like kinase 1 (DCLK1).Cost-effective and quality-assured.</p>Formula:C26H28F3N7O2Purity:98.55% - 99.28%Color and Shape:SolidMolecular weight:527.54AG126
CAS:<p>AG126 (Tyrphostin AG126) selectively inhibits the phosphorylation of ERK1 (p44) and ERK2 (p42). AG-126 weakly inhibits epidermal GFRK and platelet-derived GFRK.</p>Formula:C10H5N3O3Purity:97.35%Color and Shape:SolidMolecular weight:215.16Epieriocalyxin A
CAS:<p>Epieriocalyxin A can suppress Caco-2 colon cancer cell growth. It could be a potential drug for colon cancer therapy in the future.</p>Formula:C20H24O5Purity:97.00%Color and Shape:SolidMolecular weight:344.4DMU-212
CAS:<p>DMU-212, a Resveratrol derivative, has antimitotic, antiproliferative, antioxidant properties; induces apoptosis via ERK1/2.</p>Formula:C18H20O4Purity:99.86%Color and Shape:SolidMolecular weight:300.35SUN11602
CAS:<p>SUN11602, an aniline compound, mimics the neuroprotective mechanisms of basic fibroblast growth factor.</p>Formula:C26H37N5O2Purity:99.36%Color and Shape:SolidMolecular weight:451.6RU-301
CAS:<p>RU-301 is a novel pan-tam inhibitor</p>Formula:C21H19F3N4O4SPurity:98.87%Color and Shape:SolidMolecular weight:480.46
