ERK
ERK is a key protein in the MAPK (Mitogen-Activated Protein Kinase) signaling pathway, which is involved in transmitting signals from cell surface receptors to the DNA in the cell nucleus. ERK plays a crucial role in the regulation of various cellular processes, including proliferation, differentiation, and survival. Dysregulation of ERK signaling is associated with the development of cancer and other diseases, making it an important target for therapeutic intervention. At CymitQuimica, we offer a selection of high-quality ERK inhibitors and modulators to support your research in cell signaling, oncology, and therapeutic development.
Found 217 products of "ERK"
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Longdaysin
CAS:Longdaysin is an inhibitor of CK1α and CK1δ (IC50s: 5.6/8.8 μM). It also can inhibit ERK2 (IC50: 52 μM).Formula:C16H16F3N5Purity:99.97%Color and Shape:SolidMolecular weight:335.33Deltonin
CAS:Deltonin inhibits ERK1/2 & AKT; toxic to HepG2 (IC50: 7.66μM), C26 (IC50: 1.22μM), MDA-MB-231 cells (IC50: 1.58μM).Formula:C45H72O17Purity:98.77% - 99.79%Color and Shape:SolidMolecular weight:885.04trans-Zeatin
CAS:trans-Zeatin ((E)-Zeatin) is the member of the plant growth hormone family known as cytokinins, which regulate cell division, development, and nutrientFormula:C10H13N5OPurity:97.13% - 98.96%Color and Shape:White To Light Yellow Crystal PowderMolecular weight:219.24Ref: TM-TMS2181
1mL*10mM (DMSO)33.00€10mg37.00€25mg52.00€50mg66.00€100mg96.00€200mg128.00€500mg205.00€Gypenoside L
CAS:Gypenoside L inhibits autophagic flux and induces cell death in human esophageal cancer cells through endoplasm reticulum stress-mediated Ca2+ release.Formula:C42H72O14Purity:99.42% - 99.65%Color and Shape:SolidMolecular weight:801.01Ravoxertinib
CAS:Ravoxertinib (GDC-0994) is an effective and orally available ERK1/2 inhibitor (IC50: 1.1/0.3 nM).Formula:C21H18ClFN6O2Purity:98% - 99.87%Color and Shape:SolidMolecular weight:440.86Ref: TM-T6511
1mg38.00€2mg49.00€5mg80.00€1mL*10mM (DMSO)88.00€10mg90.00€25mg164.00€50mg268.00€100mg399.00€Bohemine
CAS:Bohemine is a cyclin-dependent kinase inhibitor.Formula:C18H24N6OPurity:99.09% - 99.53%Color and Shape:SolidMolecular weight:340.42Prosaptide TX14(A) acetate
Prosaptide TX14(A) acetate is a potent GPR37L1 and GPR37 agonist. Prosaptide Tx14(A) TFA increases both ERK1 and ERK2 phosphorylation in Schwann cells.Formula:C71H114N16O28Purity:95.29%Color and Shape:SolidMolecular weight:1639.76magnolin
CAS:Magnolin reduces the renal oxidative stress, suppresses caspase-3 activity, and increases Bcl-2 expression in vivo and in vitro.
Formula:C23H28O7Purity:98% - 99.77%Color and Shape:SolidMolecular weight:416.46FR 180204
CAS:FR 180204 is a potent and selective ATP-competitive inhibitor of ERK1 and ERK2.Formula:C18H13N7Purity:98% - 99.74%Color and Shape:SolidMolecular weight:327.34Ref: TM-T1956
1mg40.00€2mg52.00€5mg81.00€1mL*10mM (DMSO)89.00€10mg131.00€25mg210.00€50mg314.00€100mg470.00€MRTX1133
CAS:View and buy MRTX1133 from TargetMol.MRTX1133 is a potent, selective, and noncovalent inhibitor of KRAS G12D.Formula:C33H31F3N6O2Purity:97.39% - 99.6%Color and Shape:SolidMolecular weight:600.63Ref: TM-T9303
1mg177.00€5mg379.00€1mL*10mM (DMSO)502.00€10mg580.00€25mg893.00€50mg1,251.00€100mg1,639.00€200mg2,215.00€KO-947
CAS:KO-947 is a potent and specific inhibitor of ERK1/2 kinases.
Formula:C21H17N5OPurity:97.84%Color and Shape:SolidMolecular weight:355.39Astragaloside IV
CAS:Astragaloside IV suppresses ERK1/2, JNK, MMP-2/9 in breast cancer; inhibits adenovirus and protects cardiovascular, immune, digestive, nervous systems.Formula:C41H68O14Purity:99% - 99.84%Color and Shape:Hydroscopic Brown Or Yellow PowderMolecular weight:784.97Avicularin
CAS:Avicularin reduces inflammation via ERK pathway in RAW 264.7 cells and hinders lipid buildup in adipocytes by limiting glucose uptake and fatty acid synthesis.Formula:C20H18O11Purity:97.02% - 99.94%Color and Shape:White PowderMolecular weight:434.35Ref: TM-T6S0117
1mg55.00€5mg92.00€1mL*10mM (DMSO)105.00€10mg152.00€25mg268.00€50mg395.00€100mg583.00€200mg832.00€LM22B-10
CAS:LM22B-10 is an activator of TrkB/TrkC neurotrophin receptor and can induce TrkB, TrkC, ERK and AKT activation in vitro and in vivo.Formula:C27H33ClN2O4Purity:98.18%Color and Shape:SolidMolecular weight:485.01(E/Z)-BIX02188
CAS:BIX02188 inhibits MEK5 (IC50: 4.3 nM) and ERK5 (810 nM) but not MEK1/2, JNK2, or ERK2.Formula:C25H24N4O2Purity:97.39% - 98.38%Color and Shape:SolidMolecular weight:412.48Ref: TM-T6324
1mg48.00€2mg63.00€5mg119.00€1mL*10mM (DMSO)136.00€10mg216.00€25mg326.00€50mg490.00€100mg707.00€ERK1/2 inhibitor 2
CAS:ERK1/2 inhibitor 2 (ASTX029) is a selective and orally bioavailable ERK 1/2 inhibitor, with potential antineoplastic activity.Formula:C29H31ClFN5O5Purity:98.99%Color and Shape:SolidMolecular weight:584.04AZD8330
CAS:AZD8330 (ARRY-704) is a novel, selective, non-ATP competitive MEK 1/2 inhibitor with IC50 of 7 nM. Phase 1.Formula:C16H17FIN3O4Purity:98.72%Color and Shape:SolidMolecular weight:461.23Tizaterkib
CAS:Tizaterkib (AZD-0364) is a potent and selective ERK2 inhibitor.Formula:C24H24F2N8O2Purity:99.6% - 99.63%Color and Shape:SolidMolecular weight:494.5HS-1793
CAS:HS-1793, resveratrol-like, reduces HIF-1, VEGF in hypoxia, and curbs human breast cancer growth in mouse model.Formula:C16H12O3Purity:98.16% - 99.82%Color and Shape:SolidMolecular weight:252.26(E/Z)-BIX 02189
CAS:(E/Z)-BIX 02189 is a selective inhibitor of MEK5 with IC50 of 1.5 nM.Formula:C27H28N4O2Purity:98% - 99.89%Color and Shape:SolidMolecular weight:440.54Ref: TM-T2416
1mg38.00€5mg82.00€1mL*10mM (DMSO)92.00€10mg116.00€25mg210.00€50mg358.00€100mg550.00€200mg780.00€
