ERK
ERK is a key protein in the MAPK (Mitogen-Activated Protein Kinase) signaling pathway, which is involved in transmitting signals from cell surface receptors to the DNA in the cell nucleus. ERK plays a crucial role in the regulation of various cellular processes, including proliferation, differentiation, and survival. Dysregulation of ERK signaling is associated with the development of cancer and other diseases, making it an important target for therapeutic intervention. At CymitQuimica, we offer a selection of high-quality ERK inhibitors and modulators to support your research in cell signaling, oncology, and therapeutic development.
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Temuterkib
CAS:1951483-29-6
LY3214996 (Temuterkib) is a potent oral ERK1/2 inhibitor with potential cancer-fighting properties.
Formula:
C22H27N7O2S
Purity:
100% - 99.76%
Color and Shape:
Solid
Molecular weight:
453.56
Ref: TM-T4091
| 1mg | 69.00 € | ||
| 2mg | 90.00 € | ||
| 5mg | 118.00 € | ||
| 10mg | 185.00 € | ||
| 25mg | 399.00 € | ||
| 50mg | 603.00 € | ||
| 100mg | 854.00 € | ||
| 500mg | 1,734.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
magnolin
CAS:31008-18-1
Magnolin reduces the renal oxidative stress, suppresses caspase-3 activity, and increases Bcl-2 expression in vivo …
Formula:
C23H28O7
Purity:
98% - 99.57%
Color and Shape:
Solid
Molecular weight:
416.46
Ref: TM-T3857
| 20mg | 90.00 € | ||
| 1mL*10mM (DMSO) | 43.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Rubrofusarin gentiobioside
CAS:24577-90-0
Rubrofusarin gentiobioside (Rubrofusarin-6-O-beta-D-gentiobioside) decreases the expression of TGF-beta1 and fibronectin and NF-kappaB DNA binding activity.
Formula:
C27H32O15
Purity:
99.75% - 99.91%
Color and Shape:
Solid
Molecular weight:
596.53
Ref: TM-TN2165
| 1mg | 53.00 € | ||
| 5mg | 113.00 € | ||
| 10mg | 171.00 € | ||
| 25mg | 278.00 € | ||
| 50mg | 403.00 € | ||
| 100mg | To inquire | ||
| 1mL*10mM (DMSO) | 168.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
ERK5-IN-1
CAS:1234479-76-5
ERK5-IN-1 is a potent ERK5 inhibitor (IC50: 87 nM). It also inhibits LRRK2[G2019S] (IC50: 26 …
Formula:
C25H29N7O2
Purity:
99.42%
Color and Shape:
Solid
Molecular weight:
459.54
Ref: TM-T5184
| 1mg | 52.00 € | ||
| 5mg | 119.00 € | ||
| 10mg | 167.00 € | ||
| 25mg | 241.00 € | ||
| 50mg | 326.00 € | ||
| 100mg | 456.00 € | ||
| 1mL*10mM (DMSO) | 120.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Tauroursodeoxycholate
CAS:14605-22-2
Tauroursodeoxycholate (UR 906), a hydrophilic bile acid, low in humans, may treat PBC, insulin resistance, …
Formula:
C26H45NO6S
Purity:
98.12% - 99.93%
Color and Shape:
White Solid
Molecular weight:
499.7
Ref: TM-T2532
| 50mg | 54.00 € | ||
| 100mg | 68.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Loureirin B
CAS:119425-90-0
Loureirin B suppresses fibrosis by modulating MMPs/TIMPs, hindering fibroblast growth, and targeting TGF-β1/Smad2/3 pathway.
Formula:
C18H20O5
Purity:
99.33% - 99.86%
Color and Shape:
Solid
Molecular weight:
316.35
Ref: TM-T3876
| 1mg | 52.00 € | ||
| 5mg | 118.00 € | ||
| 10mg | 172.00 € | ||
| 25mg | 275.00 € | ||
| 50mg | 419.00 € | ||
| 100mg | 604.00 € | ||
| 1mL*10mM (DMSO) | 130.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
UNC569
CAS:1350547-65-7
UNC569 selectively inhibits kidney URAT1, regulating uric acid excretion and aiding gout patient's uric balance.
Formula:
C22H29FN6
Purity:
98.91%
Color and Shape:
Solid
Molecular weight:
396.5
Ref: TM-T21302
| 1mg | 45.00 € | ||
| 2mg | 59.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 142.00 € | ||
| 25mg | 306.00 € | ||
| 50mg | 502.00 € | ||
| 100mg | 717.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
DEL-22379
CAS:181223-80-3
DEL-22379 is a water-soluble ERK dimerization inhibitor with IC50 of ～0.5 μM.
Formula:
C26H28N4O3
Purity:
99.3% - 99.53%
Color and Shape:
Solid
Molecular weight:
444.53
Ref: TM-T6818
| 1mg | 35.00 € | ||
| 2mg | 51.00 € | ||
| 5mg | 74.00 € | ||
| 10mg | 122.00 € | ||
| 25mg | 214.00 € | ||
| 50mg | 344.00 € | ||
| 100mg | 512.00 € | ||
| 1mL*10mM (DMSO) | 81.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
2,5-Dihydroxyacetophenone
CAS:490-78-8
2,5-Dihydroxyacetophenone has anti-anxiety, neuroprotective, anti-inflammatory properties, and modulates cell signaling and melanogenesis.
Formula:
C8H8O3
Purity:
99.91%
Color and Shape:
Yellow Powder
Molecular weight:
152.15
Ref: TM-TCS2170
| 50mg | 35.00 € | ||
| 100mg | 49.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Butein
CAS:487-52-5
Butein is a cAMP-specific PDE inhibitor, protein tyrosine kinase inhibitor, and SIRT1 activator.Cost-effective and quality-assured.
Formula:
C15H12O5
Purity:
100% - 99.85%
Color and Shape:
Solid
Molecular weight:
272.25
Ref: TM-T6427
| 1mg | 42.00 € | ||
| 2mg | 55.00 € | ||
| 5mg | 86.00 € | ||
| 10mg | 104.00 € | ||
| 25mg | 210.00 € | ||
| 50mg | 337.00 € | ||
| 100mg | 540.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Pachymic acid
CAS:29070-92-6
Pachymic acid (3-O-Acetyltumulosic acid) is a natural product, and inhibits Akt and ERK signaling pathways.
Formula:
C33H52O5
Purity:
100% - 99.91%
Color and Shape:
White Powder
Molecular weight:
528.76
Ref: TM-T6S0619
| 1mg | 78.00 € | ||
| 5mg | 170.00 € | ||
| 10mg | 258.00 € | ||
| 25mg | 491.00 € | ||
| 50mg | 708.00 € | ||
| 100mg | 993.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Epiberberine
CAS:6873-09-2
1.
Formula:
C20H18NO4
Purity:
98.52% - 99.59%
Color and Shape:
Solid
Molecular weight:
336.36
Ref: TM-T5S2361
| 1mg | 36.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 180.00 € | ||
| 50mg | 337.00 € | ||
| 100mg | 478.00 € | ||
| 500mg | 1,068.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Astragaloside IV
CAS:84687-43-4
Astragaloside IV suppresses ERK1/2, JNK, MMP-2/9 in breast cancer; inhibits adenovirus and protects cardiovascular, immune, …
Formula:
C41H68O14
Purity:
99% - 99.84%
Color and Shape:
Hydroscopic Brown Or Yellow Powder
Molecular weight:
784.97
Ref: TM-T2973
| 5mg | 38.00 € | ||
| 10mg | 57.00 € | ||
| 25mg | 83.00 € | ||
| 50mg | 123.00 € | ||
| 100mg | 198.00 € | ||
| 500mg | 497.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
6-OAU
CAS:83797-69-7
6-OAU is a GPR84 agonist, activates it in HEK293 cells with a 105 nM EC50.
Formula:
C12H21N3O2
Purity:
99.01% - 99.68%
Color and Shape:
Solid
Molecular weight:
239.31
Ref: TM-T2036
| 1mg | 157.00 € | ||
| 2mg | 210.00 € | ||
| 5mg | 322.00 € | ||
| 10mg | 462.00 € | ||
| 25mg | 737.00 € | ||
| 50mg | 1,056.00 € | ||
| 100mg | 1,417.00 € | ||
| 1mL*10mM (DMSO) | 300.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Chrysoeriol
CAS:491-71-4
Chrysoeriol has antioxidant, antiinflammatory, antitumor, antimicrobial, antiviral, and free radical scavenging activities, it also shows …
Formula:
C16H12O6
Purity:
98.16%
Color and Shape:
Solid
Molecular weight:
300.26
Ref: TM-TN1490
| 1mg | 47.00 € | ||
| 5mg | 109.00 € | ||
| 10mg | 176.00 € | ||
| 25mg | 351.00 € | ||
| 50mg | 519.00 € | ||
| 100mg | 739.00 € | ||
| 1mL*10mM (DMSO) | 119.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
SEW2871
CAS:256414-75-2
SEW 2871 is an orally available, highly selective S1P1 agonist. It activates ERK, Akt and …
Formula:
C20H10F6N2OS
Purity:
99.62%
Color and Shape:
White Solid
Molecular weight:
440.36
Ref: TM-T2171
| 1mg | 57.00 € | ||
| 2mg | 82.00 € | ||
| 5mg | 152.00 € | ||
| 10mg | 250.00 € | ||
| 25mg | 405.00 € | ||
| 50mg | 597.00 € | ||
| 1mL*10mM (DMSO) | 145.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
BIX02189
CAS:1265916-41-3
BIX02189 is a potent and selective inhibitor of MEK5 and ERK5(IC50 : 1.5 nM and …
Formula:
C27H28N4O2
Purity:
97.84%
Color and Shape:
Solid
Molecular weight:
440.54
Ref: TM-T21295
| 2mg | 34.00 € | ||
| 5mg | 49.00 € | ||
| 10mg | 72.00 € | ||
| 25mg | 122.00 € | ||
| 50mg | 203.00 € | ||
| 100mg | 301.00 € | ||
| 200mg | 435.00 € | ||
| 1mL*10mM (DMSO) | 56.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PD98059
CAS:167869-21-8
PD98059 is an MEK inhibitor that inhibits MEK1 and MEK2 (IC50=2/50 μM) and is non-ATP-competitive.
Formula:
C16H13NO3
Purity:
100% - 99.66%
Color and Shape:
Yellow Solid
Molecular weight:
267.28
Ref: TM-T2623
| 5mg | 45.00 € | ||
| 10mg | 57.00 € | ||
| 25mg | 88.00 € | ||
| 50mg | 111.00 € | ||
| 100mg | 183.00 € | ||
| 200mg | 269.00 € | ||
| 500mg | 449.00 € | ||
| 1mL*10mM (DMSO) | 58.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Piperlongumine
CAS:20069-09-4
Piperlongumine (Piplartine) is a natural alkaloid from Piper longum L.
Formula:
C17H19NO5
Purity:
97.03% - 99.89%
Color and Shape:
Solid
Molecular weight:
317.34
Ref: TM-T6947
| 10mg | 35.00 € | ||
| 25mg | 54.00 € | ||
| 50mg | 86.00 € | ||
| 100mg | 118.00 € | ||
| 1mL*10mM (DMSO) | 36.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Isomerazin
CAS:1088-17-1
Isomerazin (Isomeranzin) has anti-inflammatory activity, it suppresses inflammation by inhibiting M1 macrophage polarization through the …
Formula:
C15H16O4
Purity:
99.8%
Color and Shape:
Solid
Molecular weight:
260.29
Ref: TM-TN1786
| 1mg | 95.00 € | ||
| 5mg | 244.00 € | ||
| 10mg | 360.00 € | ||
| 25mg | 593.00 € | ||
| 50mg | 833.00 € | ||
| 1mL*10mM (DMSO) | 221.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
