Raf
Raf kinases are key components of the MAPK/ERK signaling pathway, playing a critical role in transmitting signals from the cell membrane to the nucleus. Raf activation leads to the phosphorylation of MEK, which subsequently activates ERK, influencing cell division, differentiation, and survival. Mutations in Raf, particularly in B-Raf, are associated with various cancers, making Raf a critical target in cancer therapy. At CymitQuimica, we provide a variety of Raf inhibitors and modulators to support your research in oncology, signal transduction, and therapeutic development.
Read more
Doramapimod
CAS:285983-48-4
Doramapimod (BIRB 796) is a highly potent inhibitor of p38 MAPK (Kd: 0.1 nM), but …
Formula:
C31H37N5O3
Purity:
97.73% - 98.80%
Color and Shape:
Solid
Molecular weight:
527.66
Ref: TM-T6277
| 1g | 562.00 € | ||
| 5mg | 37.00 € | ||
| 10mg | 55.00 € | ||
| 25mg | 79.00 € | ||
| 50mg | 92.00 € | ||
| 100mg | 127.00 € | ||
| 200mg | 225.00 € | ||
| 500mg | 379.00 € | ||
| 1mL*10mM (DMSO) | 44.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
TAK-580
CAS:1096708-71-2
TAK-580 (MLN2480) is an oral, selective pan-Raf kinase inhibitor in Clinicalal trials.
Formula:
C17H12Cl2F3N7O2S
Purity:
99.25% - 99.77%
Color and Shape:
Solid
Molecular weight:
506.29
Ref: TM-T6895
| 1mg | 52.00 € | ||
| 2mg | 74.00 € | ||
| 5mg | 103.00 € | ||
| 10mg | 180.00 € | ||
| 25mg | 303.00 € | ||
| 50mg | 445.00 € | ||
| 100mg | 655.00 € | ||
| 1mL*10mM (DMSO) | 116.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
Regorafenib Hydrochloride
CAS:835621-07-3
Regorafenib HCl (BAY73-4506) is an oral inhibitor targeting angiogenic, stromal, and cancer kinases with strong …
Formula:
C21H16Cl2F4N4O3
Purity:
99.56%
Color and Shape:
Solid
Molecular weight:
519.28
Ref: TM-T8402
| 5mg | 35.00 € | ||
| 10mg | 51.00 € | ||
| 25mg | 80.00 € | ||
| 50mg | 96.00 € | ||
| 100mg | 144.00 € | ||
| 500mg | 350.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
AZ 628
CAS:878739-06-1
AZ628 is a new pan-Raf inhibitor for BRAF, BRAFV600E, and c-Raf-1 with IC50 of 105 …
Formula:
C27H25N5O2
Purity:
98.54%
Color and Shape:
Solid
Molecular weight:
451.52
Ref: TM-T6318
| 2mg | 46.00 € | ||
| 5mg | 66.00 € | ||
| 10mg | 92.00 € | ||
| 25mg | 172.00 € | ||
| 50mg | 274.00 € | ||
| 100mg | 354.00 € | ||
| 1mL*10mM (DMSO) | 66.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
K-Ras-IN-1
CAS:84783-01-7
K-Ras-IN-1 is a K-Ras inhibitor.
Formula:
C11H13NOS
Purity:
98.72%
Color and Shape:
Solid
Molecular weight:
207.29
Ref: TM-T5469
| 2mg | 46.00 € | ||
| 5mg | 70.00 € | ||
| 10mg | 101.00 € | ||
| 25mg | 182.00 € | ||
| 50mg | 284.00 € | ||
| 100mg | 424.00 € | ||
| 200mg | 588.00 € | ||
| 1mL*10mM (DMSO) | 77.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
Raf inhibitor 1 dihydrochloride
CAS:1191385-19-9
Raf inhibitor 1 dihydrochloride (B-Raf inhibitor 1 dihydrochloride) is a potent and selective B-Raf inhibitor.
Formula:
C26H19ClN8HCl
Purity:
98.19% - 98.44%
Color and Shape:
Solid
Molecular weight:
551.86
Ref: TM-T4167
| 1mg | 49.00 € | ||
| 2mg | 64.00 € | ||
| 5mg | 103.00 € | ||
| 10mg | 180.00 € | ||
| 25mg | 300.00 € | ||
| 50mg | 445.00 € | ||
| 100mg | 652.00 € | ||
| 500mg | 1,378.00 € | ||
| 1mL*10mM (DMSO) | 188.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
Lonafarnib
CAS:193275-84-2
Lonafarnib (Sch66336) is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B, and N-ras (IC50: 1.9/5.2/2.8 …
Formula:
C27H31Br2ClN4O2
Purity:
98% - 99.04%
Color and Shape:
Solid
Molecular weight:
638.82
Ref: TM-T6302
| 1mg | 48.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 153.00 € | ||
| 25mg | 298.00 € | ||
| 50mg | 472.00 € | ||
| 100mg | 658.00 € | ||
| 1mL*5mM (DMSO) | 165.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
6H05
CAS:1469338-01-9
6H05 (K-Ras inhibitor) is a selective, allosteric inhibitor of oncogenic mutant K-Ras(G12C).
Formula:
C20H30ClN3O2S3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
476.12
Ref: TM-T1931
| 5mg | 127.00 € | ||
| 10mg | 215.00 € | ||
| 25mg | 355.00 € | ||
| 50mg | 527.00 € |
Estimated delivery in United States, on Tuesday 20 May 2025
PLX7904
CAS:1393465-84-3
PLX7904 (PB04), a selective RAF inhibitor, blocks ERK1/2 in mutant BRAF melanoma without activating it …
Formula:
C24H22F2N6O3S
Purity:
96.27% - 96.27%
Color and Shape:
Solid
Molecular weight:
512.53
Ref: TM-T6949
| 5mg | 49.00 € | ||
| 10mg | To inquire | ||
| 50mg | To inquire | ||
| 1mL*10mM (DMSO) | 58.00 € |
Estimated delivery in United States, on Tuesday 20 May 2025
Sulindac sulfide
CAS:49627-27-2
Sulindac sulfide: NSAID targeting COX-1, inhibits Ras-Raf-1 and gamma-secretase (IC50: 20.2 μM), active sulinic acid …
Formula:
C20H17FO2S
Purity:
99.68%
Color and Shape:
Solid
Molecular weight:
340.41
Ref: TM-T13037
| 10mg | 37.00 € | ||
| 25mg | 52.00 € | ||
| 50mg | To inquire | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Tuesday 20 May 2025
GSK2008607
CAS:1244644-50-5
GSK2008607 is a potent B-RafV600E inhibitor with anticancer activity and can be used to study …
Formula:
C31H28F3N7O3S2
Purity:
99%
Color and Shape:
Solid
Molecular weight:
667.72
Ref: TM-T27454
| 1mg | 333.00 € | ||
| 5mg | 787.00 € | ||
| 10mg | 1,074.00 € | ||
| 25mg | 1,510.00 € | ||
| 50mg | 1,882.00 € | ||
| 100mg | 2,375.00 € | ||
| 500mg | 4,655.00 € |
Estimated delivery in United States, on Tuesday 3 Jun 2025
RMC-0331
CAS:2488788-52-7
RMC-0331 (RM-023) is an oral SOS1 inhibitor with potential to block RAS activation and anticancer …
Formula:
C22H25ClF3N5O3
Purity:
99.81%
Color and Shape:
Solid
Molecular weight:
499.91
Ref: TM-T38170
| 1mg | 145.00 € | ||
| 2mg | 210.00 € | ||
| 5mg | 354.00 € | ||
| 10mg | 630.00 € | ||
| 25mg | 1,301.00 € |
Estimated delivery in United States, on Tuesday 3 Jun 2025
MCP110
CAS:521310-51-0
MCP110 is an inhibitor of the interaction of Ras with Raf-1 and can be used …
Formula:
C33H36N2O3
Purity:
97.18%
Color and Shape:
Oil
Molecular weight:
508.65
Ref: TM-T24437
| 1mg | 37.00 € | ||
| 5mg | 97.00 € | ||
| 10mg | 169.00 € | ||
| 25mg | 291.00 € | ||
| 50mg | 423.00 € | ||
| 100mg | 562.00 € | ||
| 500mg | 1,121.00 € | ||
| 1mL*10mM (DMSO) | 108.00 € |
Estimated delivery in United States, on Tuesday 3 Jun 2025
SOS1-IN-15
CAS:2793404-47-2
SOS1-IN-15 is an orally active and potent SOS1 inhibitor with potential antitumor activity.SOS1-IN-15 is used …
Formula:
C28H27F3N6O2
Purity:
98.32%
Color and Shape:
Liquid
Molecular weight:
536.548
Ref: TM-T73164
| 1mg | 130.00 € | ||
| 5mg | 311.00 € | ||
| 10mg | 512.00 € | ||
| 25mg | 938.00 € |
Estimated delivery in United States, on Tuesday 3 Jun 2025
BRAF inhibitor
CAS:918505-61-0
BRAF inhibitor is an inhibitor of B-Raf.
Formula:
C22H18F2N4O3S
Purity:
97.95% - 98.27%
Color and Shape:
Solid
Molecular weight:
456.47
Ref: TM-T10599
| 1mg | 47.00 € | ||
| 5mg | 93.00 € | ||
| 10mg | 144.00 € | ||
| 25mg | 250.00 € | ||
| 50mg | 393.00 € | ||
| 100mg | 560.00 € | ||
| 200mg | 812.00 € | ||
| 1mL*10mM (DMSO) | 104.00 € |
Estimated delivery in United States, on Tuesday 3 Jun 2025
GDC-0879
CAS:905281-76-7
GDC-0879 (AR-00341677) is a novel, potent and selective B-Raf inhibitor with IC50 of 0.13 nM …
Formula:
C19H18N4O2
Purity:
95.76%
Color and Shape:
Solid
Molecular weight:
334.37
Ref: TM-T6320
| 1mg | 38.00 € | ||
| 2mg | 49.00 € | ||
| 5mg | 79.00 € | ||
| 10mg | 111.00 € | ||
| 25mg | 216.00 € | ||
| 50mg | 354.00 € | ||
| 100mg | 567.00 € | ||
| 200mg | 807.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Tuesday 3 Jun 2025
NSC-70220
CAS:4551-00-2
SOS1-IN-1 is an inhibitor of SOS1.
Formula:
C22H15NO2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
325.36
Ref: TM-T12978
| 2mg | 230.00 € | ||
| 5mg | 283.00 € | ||
| 25mg | 938.00 € | ||
| 50mg | 1,293.00 € | ||
| 100mg | 1,768.00 € |
Estimated delivery in United States, on Tuesday 3 Jun 2025
B-Raf IN 13
CAS:2573782-74-6
B-Raf IN 13 is a potent B-Raf inhibitor with anticancer activity.B-Raf IN 13 has an …
Formula:
C19H19ClFN3O4S
Purity:
95.83% - 98.39%
Color and Shape:
Soild
Molecular weight:
439.89
Ref: TM-T67862
| 25mg | 1,444.00 € |
Estimated delivery in United States, on Tuesday 3 Jun 2025
B-Raf IN 15
CAS:832107-31-0
B-Raf IN 15 is a BRAF inhibitor that inhibits BRAFWT and BRAFV600E and can be …
Formula:
C19H15N3OS
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
333.41
Ref: TM-T78183
| 1mg | 57.00 € | ||
| 5mg | 120.00 € | ||
| 10mg | 188.00 € | ||
| 25mg | 329.00 € | ||
| 1mL*10mM (DMSO) | 137.00 € |
Estimated delivery in United States, on Tuesday 17 Jun 2025
B-Raf IN 16
CAS:2304746-24-3
B-Raf IN 16, a BRAF inhibitor, belongs to cyclic iminopyrimidine derivatives and can be used …
Formula:
C20H19N5O3S
Purity:
98.59% - 99.56%
Color and Shape:
Liquid
Molecular weight:
409.46
Ref: TM-T79830
| 1mg | 185.00 € | ||
| 5mg | 459.00 € | ||
| 10mg | 657.00 € | ||
| 25mg | 1,026.00 € | ||
| 50mg | 1,415.00 € |
Estimated delivery in United States, on Tuesday 17 Jun 2025
