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Membrane Transporter/Ion Channel

Membrane Transporter/Ion Channel

Membrane transporter and ion channel inhibitors are compounds that block the function of proteins responsible for the transport of ions, nutrients, and other molecules across cell membranes. These inhibitors are crucial for studying the regulation of cellular homeostasis, signal transduction, and neurotransmission. Membrane transporter and ion channel inhibitors are also important in developing treatments for disorders such as epilepsy, cardiovascular diseases, and metabolic syndromes. At CymitQuimica, we provide a diverse selection of high-quality membrane transporter and ion channel inhibitors to support your research in physiology, neuroscience, and pharmacology.

Subcategories of "Membrane Transporter/Ion Channel"

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Found 2290 products of "Membrane Transporter/Ion Channel"

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  • CS-526

    CAS:
    <p>CS-526 is a reversible proton pump inhibitor targeting the K+ site on H+,K+-ATPase, reducing gastric acid secretion and preventing mucosal lesions.</p>
    Formula:C20H22FN3O
    Color and Shape:Solid
    Molecular weight:339.41
  • Pumaprazole

    CAS:
    <p>Pumaprazole (BY-841) is an antagonist of a reversible proton pump.</p>
    Formula:C19H22N4O2
    Purity:99.91%
    Color and Shape:Solid
    Molecular weight:338.4
  • L 691121

    CAS:
    <p>L 691121 is a class III antiarrhythmic compound. It also blocks potassium currents.</p>
    Formula:C22H25ClN4O5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:492.98
  • Caroverine

    CAS:
    Caroverine is a potential chemotherapeutical agent in HNSCC cell lines.
    Formula:C22H27N3O2
    Color and Shape:Solid
    Molecular weight:365.47
  • TCS 46b

    CAS:
    <p>TCS 46b is a NR1A/NR2B NMDA receptor antagonist with oral activity.</p>
    Formula:C22H23N3O
    Purity:99.78% - 99.78%
    Color and Shape:Solid
    Molecular weight:345.44
  • BPO-27 racemate

    CAS:
    BPO-27 racemate (BPO-27 (racemate)) is an effective CFTR inhibitor with IC50 of 8 nM.
    Formula:C26H18BrN3O6
    Purity:97.67% - 98.86%
    Color and Shape:Solid
    Molecular weight:548.34
  • Diproqualone

    CAS:
    <p>Diproqualone, analogous to methaqualone, exhibits sedative, anxiolytic, anti-inflammatory, and analgesic properties [1].</p>
    Formula:C12H14N2O3
    Color and Shape:Solid
    Molecular weight:234.255
  • XR9051 Hydrochloride

    CAS:
    <p>XR9051 Hydrochloride, a potent modulator of P-glycoprotein-mediated multidrug resistance (MDR), inhibits the binding of cytotoxics to P-glycoprotein.</p>
    Formula:C39H39ClN4O5
    Color and Shape:Solid
    Molecular weight:679.21
  • 6-Iodoamiloride

    CAS:
    <p>6-Iodoamiloride is a potent inhibitor of acid-sensing ion channel 1 (ASIC1), exhibiting an IC50 value of 88 nM.</p>
    Formula:C6H8IN7O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:321.08
  • NPBA

    CAS:
    <p>NPBA, a potassium K2P channel TASK-3 (KCNK9) agonist, concurrently functions as a blocker of the tandem pore domain weak inward rectifying K+ channel (TWIK2). This compound effectively inhibits NLRP3 inflammasome activation in macrophages [1].</p>
    Formula:C16H14F3N3O3
    Color and Shape:Solid
    Molecular weight:353.3
  • Crobenetine hydrochloride

    CAS:
    <p>Crobenetine hydrochloride, a sodium channel antagonist, is used potentially for the treatment of stroke.</p>
    Formula:C25H34ClNO2
    Color and Shape:Solid
    Molecular weight:416
  • Nalanthalide

    CAS:
    <p>Nalanthalide, serving as a voltage-gated potassium channel Kv1.3 blocker (IC50 = 3.9 µM) with potential immunosuppressive properties, is applicable in the research of inflammatory immune diseases including neuroinflammation [1] [2].</p>
    Formula:C30H44O5
    Color and Shape:Solid
    Molecular weight:484.67
  • COR659

    CAS:
    <p>COR659: suppresses alcohol/chocolate intake in rats; enhances GABAB receptor, blocks CB1 receptor.</p>
    Formula:C16H16ClNO3S
    Purity:99.75%
    Color and Shape:Solid
    Molecular weight:337.82
  • Ebio1

    CAS:
    <p>Ebio1, a selective activator of the voltage-gated potassium channel KCNQ2, enhances channel conductance by promoting the formation of an expanded gate at a saturation voltage of +50 mV, leading to increased channel activity [1].</p>
    Formula:C19H14FNO
    Color and Shape:Solid
    Molecular weight:291.32
  • GSK 2833503A

    CAS:
    <p>GSK 2833503A: potent TRPC6/3 antagonist; IC50: 3-16/21-100 nM; &gt;63x selective; inhibits cardiac hypertrophy signaling.</p>
    Formula:C18H21ClFN3OS
    Color and Shape:Solid
    Molecular weight:381.9
  • Iganidipine HCl

    CAS:
    NKY-722 (HCl), also known as Iganidipine, is a calcium channel blocker potentially for the treatment of glaucoma.
    Formula:C28H40Cl2N4O6
    Color and Shape:Solid
    Molecular weight:599.55
  • PU-48

    CAS:
    <p>PU-48 is a potent inhibitor of urea transporters A (UT-A) with an IC50 value of 0.32 μM, exhibiting a significant diuretic effect in mouse models without</p>
    Formula:C14H12N2O3S
    Color and Shape:Solid
    Molecular weight:288.32
  • URAT1 inhibitor 8

    CAS:
    <p>URAT1 Inhibitor 8 (example 247) serves as a highly potent inhibitor of URAT1, demonstrating an IC50 value of 0.001 μM.</p>
    Formula:C19H13ClFN3O4S
    Color and Shape:Solid
    Molecular weight:433.84
  • NaV1.7 Blocker-801

    CAS:
    <p>NaV1.7 Blocker-801 is a potent NaV1.7 blocker.</p>
    Formula:C20H15ClF2N6O3S2
    Color and Shape:Solid
    Molecular weight:524.95
  • MCT1-IN-2

    CAS:
    <p>SR13800 is a monocarboxylate transporter 1 (MCT1) inhibitor with cell-permeable.</p>
    Formula:C25H29N3O2S
    Color and Shape:Solid
    Molecular weight:435.58