Membrane Transporter/Ion Channel
Membrane transporter and ion channel inhibitors are compounds that block the function of proteins responsible for the transport of ions, nutrients, and other molecules across cell membranes. These inhibitors are crucial for studying the regulation of cellular homeostasis, signal transduction, and neurotransmission. Membrane transporter and ion channel inhibitors are also important in developing treatments for disorders such as epilepsy, cardiovascular diseases, and metabolic syndromes. At CymitQuimica, we provide a diverse selection of high-quality membrane transporter and ion channel inhibitors to support your research in physiology, neuroscience, and pharmacology.
Subcategories of "Membrane Transporter/Ion Channel"
- ABC(3 products)
- ATPase(100 products)
- Adiponectin receptor(5 products)
- CFTR(66 products)
- CGRP Receptor(54 products)
- Calcium Channel(545 products)
- Chloride channel(53 products)
- GABA Receptor(369 products)
- Monoamine Transporter(30 products)
- Monocarboxylate transporter(18 products)
- NKCC(2 products)
- NPC1L1(3 products)
- Na-K-Cl cotransporter(10 products)
- OAT(32 products)
- OCT(7 products)
- P-gp(55 products)
- Potassium Channel(283 products)
- Proton pump(41 products)
- SGLT(31 products)
- Sodium Channel(219 products)
- TRP/TRPV Channel(96 products)
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Found 2586 products of "Membrane Transporter/Ion Channel"
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P-gp modulator 3
P-gp modulator 3 (Compound 37) is a potent, competitive, metabotropic P-glycoprotein (P-gp) modulator.Formula:C31H37N3O5Color and Shape:SolidMolecular weight:531.64Cav 3.2 inhibitor 1
Cav 3.2 inhibitor 1 targets T-type calcium channels, weakly binds D2 receptors, and aids physical and visceral pain research.Formula:C32H39N3OColor and Shape:SolidMolecular weight:481.67DAD
DAD is an ion channel blocker (blocks voltage-gated potassium channels) and is a third generation photoelectric switch that responds to visible light.Formula:C26H40N6OColor and Shape:SolidMolecular weight:452.64P-gp/BCRP-IN-1
CAS:P-gp/BCRP-IN-1, safe and oral, inhibits P-gp/BCRP transporters, enhancing Paclitaxel bioavailability.Formula:C27H25ClN4O3Color and Shape:SolidMolecular weight:488.97TRPC5-IN-4
CAS:TRPC5-IN-4: Potent, safe inhibitor; IC50 14.07 nM (TRPC5), 65 nM (TRPC4); non-toxic to liver/kidney cells; for CKD research.Formula:C18H11ClF4N4O3Color and Shape:SolidMolecular weight:442.75Suloctidil HCl
CAS:Suloctidil HCl is a peripheral vascular dilator.Formula:C20H36ClNOSColor and Shape:SolidMolecular weight:374.02Tuclazepam
CAS:Tuclazepam (KC 1956) is a derivative of the benzodiazepine class of drugs, exhibiting anti-anxiety and sedative properties.Formula:C17H16Cl2N2OColor and Shape:SolidMolecular weight:335.23N-Depropylpropafenone
CAS:N-Depropylpropafenone, an active metabolite of Propafenone, is produced through the metabolism by the CYP450 enzyme system (primarily CYP2D6). It functions by blocking sodium ion channels, thereby delaying the depolarization process in myocardial cells and exhibiting antiarrhythmic properties.Formula:C18H21NO3Color and Shape:SolidMolecular weight:299.36Desmethylflunitrazepam
CAS:Desmethylflunitrazepam (Norflunitrazepam) is a benzodiazepine derivative and an active metabolite of Flunitrazepam.Formula:C15H10FN3O3Color and Shape:SolidMolecular weight:299.26SC-435 mesylate
CAS:SC-435 is an ileal apical sodium co-dependent bile acid transporter (ASBT). SC-435 inhibits plasma cholesterol.Formula:C37H59N3O7S2Purity:98%Color and Shape:SolidMolecular weight:722.01cis-KV1.3-IN-1
CAS:cis-KV1.3-IN-1, also known as Compound cis-18, is the cis-isomer of KV1.3-IN-1 and functions as an inhibitor of the KV1.3 channel. In Xenopus laevis oocytes expressing human hKV1.3, cis-KV1.3-IN-1 (10 μM) achieves an inhibition rate of 25.53% against KV1.3.Formula:C23H30N2O4SColor and Shape:SolidMolecular weight:430.56Lu AF90103
CAS:Lu AF90103 (Compound 42e) is the methyl ester prodrug of compound 42d, capable of crossing the blood-brain barrier. Compound 42d acts as a partial agonist of the GluN1/GluN2B complex, with an efficacy of 24% and an EC50 value of 78 nM. Lu AF90103 plays a significant role in neuropsychiatric disorder research.Formula:C13H15N3O3SColor and Shape:SolidMolecular weight:293.342Cav 2.2/3.2 blocker 1
Compound 9e is a Cav 2.2/3.2 blocker; IC50: 1.22 μM & 80 μM, respectively; penetrates CNS.Formula:C28H30N2O3Color and Shape:SolidMolecular weight:442.55Ro-51
CAS:dual P2X3 and P2X2/3 antagonistFormula:C17H23IN4O4Purity:98%Color and Shape:SolidMolecular weight:474.29Quinacainol dihydrochloride
CAS:Quinacainol dihydrochloride (PK 10139 dihydrochloride) is the bis(2 hydrochloride) salt form of Quinacainol. It acts as an inhibitor of the sodium current, with an EC50 of 95 µM. This compound displays antiarrhythmic activity by modulating the electrophysiological properties of the heart.
Formula:C21H32Cl2N2OColor and Shape:SolidMolecular weight:399.398IAB15
CAS:IAB15 is a potent inhibitor of T-type calcium channel that can be used in the research of epilepsy [1].Formula:C15H14F3NO2Color and Shape:SolidMolecular weight:297.27SGE-516
CAS:SGE516: neuroactive steroid, enhances GABAA, lowers neuronal activity, protects from seizures.Formula:C23H35N3O2Purity:98%Color and Shape:SolidMolecular weight:385.54TTA-P1
CAS:TTA-P1: potent T-type calcium channel inhibitor; impacts neuron firing, hormone secretion, cell growth; potential in absence epilepsy research.Formula:C19H27Cl2FN2OColor and Shape:SolidMolecular weight:389.33YY-23
CAS:YY-23 is a selective NMDAR (containing GluN2C or GluN2D) inhibitor. By inhibiting NMDARs with GluN2D on GABAergic interneurons in the prefrontal cortex, YY-23 suppresses GABAergic neurotransmission and enhances excitatory transmission. YY-23 exhibits antidepressant activity and is useful for neurological disease research.
Formula:C33H54O8Color and Shape:SolidMolecular weight:578.777LY3130481
CAS:LY3130481: TARP γ-8 dependent AMPA receptor blocker; selectively targets AMPA/TARP γ-8 with 65 nM IC50.Formula:C19H18N4O3SColor and Shape:SolidMolecular weight:382.44
