Membrane Transporter/Ion Channel
Membrane transporter and ion channel inhibitors are compounds that block the function of proteins responsible for the transport of ions, nutrients, and other molecules across cell membranes. These inhibitors are crucial for studying the regulation of cellular homeostasis, signal transduction, and neurotransmission. Membrane transporter and ion channel inhibitors are also important in developing treatments for disorders such as epilepsy, cardiovascular diseases, and metabolic syndromes. At CymitQuimica, we provide a diverse selection of high-quality membrane transporter and ion channel inhibitors to support your research in physiology, neuroscience, and pharmacology.
Subcategories of "Membrane Transporter/Ion Channel"
- ABC(3 products)
- ATPase(100 products)
- Adiponectin receptor(5 products)
- CFTR(66 products)
- CGRP Receptor(54 products)
- Calcium Channel(545 products)
- Chloride channel(53 products)
- GABA Receptor(369 products)
- Monoamine Transporter(30 products)
- Monocarboxylate transporter(18 products)
- NKCC(2 products)
- NPC1L1(3 products)
- Na-K-Cl cotransporter(10 products)
- OAT(32 products)
- OCT(7 products)
- P-gp(55 products)
- Potassium Channel(283 products)
- Proton pump(41 products)
- SGLT(31 products)
- Sodium Channel(219 products)
- TRP/TRPV Channel(96 products)
Show 13 more subcategories
Found 2586 products of "Membrane Transporter/Ion Channel"
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Cav 3.2 inhibitor 2
Cav 3.2 inhibitor 2 blocks T-type Ca2+ channels (IC50=0.09339 μM) and reduces mouse somatic/visceral pain. Used for intractable pain studies.Formula:C32H37F2N3OColor and Shape:SolidMolecular weight:517.65MSK-195
CAS:MSK-195 is an effective TRPV1 agonist.Formula:C28H40N2O5Purity:98%Color and Shape:SolidMolecular weight:484.63Kv7.2/Kv7.3 modulator-1
CAS:Kv7.2/Kv7.3 modulator-1 (compound 6a) acts as a modulator for Kv7.2/Kv7.3 channels, with a pEC50 value of 7.96 for opening these channels. Kv7.2/Kv7.3 modulator-1 is applicable in research related to epilepsy, depression, brain injury, and pain.Formula:C20H21F4N3O3Color and Shape:SolidMolecular weight:427.393SR 33805 oxalate
CAS:Ca2+ channel antagonistFormula:C34H42N2O9SPurity:98%Color and Shape:SolidMolecular weight:654.77T-Type calcium channel inhibitor 2
Compound 6g inhibits T-type Ca channels (IC50: Cav3.1-31μM, Cav3.2-83μM), cytotoxic to A549 (IC50: 5μM) & HCT-116 cells (IC50: 6.4μM).Formula:C36H39FN4OSColor and Shape:SolidMolecular weight:594.78ATP synthase inhibitor 2
CAS:ATP synthase inhibitor 2 blocks P. aeruginosa ATP synthase; IC50=10 μg/mL, fully inhibits at 128 μg/mL.Formula:C21H22N2O3SColor and Shape:SolidMolecular weight:382.48264W94
CAS:264W94 robustly inhibits IBAT, induces CYP7A1, and significantly reduces cholesterol.Formula:C23H31NO4SPurity:98%Color and Shape:SolidMolecular weight:417.56CFTR corrector 18
CAS:CFTRcorrector 18 (Compound I-99) acts as a modulator of the cystic fibrosis transmembrane conductance regulator (CFTR). It enhances the processing and trafficking of CFTR, thereby increasing the amount of CFTR present on the cell surface. CFTRcorrector 18 holds potential for research in cystic fibrosis (CF).Formula:C38H40N6O5SColor and Shape:SolidMolecular weight:692.826P2X4-IN-1
CAS:P2X4-IN-1 is an orally active P2X4 inhibitor. P2X4-IN-1 is applicable in research focused on disease prevention.Formula:C18H14ClN5O3SColor and Shape:SolidMolecular weight:415.85ML-SI1
CAS:ML-SI1, a racemic mixture of diastereoisomers, is a TRPML inhibitor and acts on TRPML1 (IC50: 15 μM).Formula:C23H26Cl2N2O3Color and Shape:SolidMolecular weight:449.373-Bromoamphetamine hydrochloride
CAS:3-Bromoamphetamine hydrochloride is a para-substituted amphetamine that functions as a monoamine releaser.Formula:C9H13BrClNColor and Shape:SolidMolecular weight:250.563PF-06305591 dihydrate
PF-06305591 dihydrate is a potent and highly selective voltage gated sodium channel NaV1.8 blocker (IC 50 = 15 nM) with an excellent preclinical in vitro ADMEFormula:C15H26N4O3Color and Shape:SolidMolecular weight:310.39Mibefradil dihydrochloride hydrate
CAS:Mibefradil dihydrochloride hydrate is a long-acting antihypertensive blocking high-voltage L calcium channels.Formula:C29H42Cl2FN3O4Color and Shape:SolidMolecular weight:586.57LY 235959
CAS:LY 235959 is a NMDA receptor antagonist.Formula:C11H20NO5PPurity:98%Color and Shape:SolidMolecular weight:277.25CRM1 degrader 1
CRM1 degrader 1 (1l) is a low-toxic CRM1 degrader that induces apoptosis in gastric carcinoma and selectively inhibits the proliferation of gastric cancer[1].Formula:C16H20O3Color and Shape:SolidMolecular weight:260.33PDE2 inhibitor 6
CAS:PDE2 inhibitor6 (Compound 1) is an orally active phosphodiesterase (PDE) inhibitor, effectively inhibiting PDE2A, PDE3B, and PDE10A2 with IC50 values of 0.95 nM, 6.17 μM (pIC50=5.21), and 87.1 nM (pIC50=7.06), respectively. It modulates AMPA receptor activity, enhances synaptic plasticity, and improves learning and memory in rat models. Furthermore, PDE2 inhibitor6 possesses blood-brain barrier permeability.
Formula:C20H22F2N6OColor and Shape:SolidMolecular weight:400.425Metaphit methylsulfate
CAS:Metaphit methylsulfate is a specific PCP antagonist and an acylating agent for the [3H] phencyclidine binding site in rat brain homogenate. It inhibits PCP-induced motor activity through a presynaptic mechanism.Formula:C19H28N2O3S2Color and Shape:SolidMolecular weight:396.567URAT1 inhibitor 3
URAT1 inhibitor 3: potent oral URAT1 blocker, IC50=0.8 nM, for gout/hyperuricemia study.Formula:C14H8Cl2N2O2Color and Shape:SolidMolecular weight:307.13Unoprostone
CAS:Unoprostone is a prostaglandin F2α analogs (PGAs), and reduces intraocular pressure and is used topically for glaucoma or ocular hypertension.Formula:C22H38O5Purity:98%Color and Shape:SolidMolecular weight:382.53S-8510 phosphate
CAS:S-8510 phosphate is an agonist of inverse Benzodiazepine (BDZ) receptor(Kis of 34.6 nM, 36.2 nM for –GABA and +GABA respectively).Formula:C12H13N4O6PPurity:98%Color and Shape:SolidMolecular weight:340.23
