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Membrane Transporter/Ion Channel

Membrane Transporter/Ion Channel

Membrane transporter and ion channel inhibitors are compounds that block the function of proteins responsible for the transport of ions, nutrients, and other molecules across cell membranes. These inhibitors are crucial for studying the regulation of cellular homeostasis, signal transduction, and neurotransmission. Membrane transporter and ion channel inhibitors are also important in developing treatments for disorders such as epilepsy, cardiovascular diseases, and metabolic syndromes. At CymitQuimica, we provide a diverse selection of high-quality membrane transporter and ion channel inhibitors to support your research in physiology, neuroscience, and pharmacology.

Subcategories of "Membrane Transporter/Ion Channel"

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Found 2293 products of "Membrane Transporter/Ion Channel"

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  • CymitQuimica logo
    Targetmol
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    Ebio3

    <p>Ebio3 is a selective potassium ion channel (KCNQ2) inhibitor with an IC50 of 1.2 nM. It binds to the KCNQ2 channel via its hydrophobic tail, causing the inward movement of the S6 helix, which results in the closure of the internal gate. The inhibitory effect of Ebio3 is equally effective on pathogenic KCNQ2 mutants, such as R75C and I238L, reducing their outward current by approximately 80%. Ebio3 holds potential for research in neurological disorders like epilepsy.</p>
    Formula:C19H23F2N3O2
    Color and Shape:Solid
    Molecular weight:363.4

    Ref: TM-T205242

  • SNX-482
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    SNX-482

    CAS:
    Potent CaV2.3 calcium channel blocker, selective, voltage-dependent, with 30 nM IC50. Offers antinociceptive effects on C and Aδ fibres.
    Formula:C192H274N52O60S7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:4495.01

    Ref: TM-TP2118

  • Levamlodipine besylate Hemipentahydrate
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    Levamlodipine besylate Hemipentahydrate

    CAS:
    <p>Levamlodipine besylate hemipentahydrate is the besylate hemipentahydrate salt form of Levamlodipine. It is an orally effective calcium channel blocker with antioxidative and vasodilatory properties. This compound can reduce serum malondialdehyde (MDA) levels, enhance the activity of superoxide dismutase (SOD), and alleviate oxidative stress. Levamlodipine besylate hemipentahydrate is relevant for research in vascular dementia, hypertension, and cerebrovascular diseases.</p>
    Formula:C20H25ClN2O5·C6H6O3SH2O
    Color and Shape:Solid
    Molecular weight:1224.18

    Ref: TM-T204904

  • ProTx II
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    ProTx II

    CAS:
    <p>Selective NaV1.7 inhibitor, alters activation, reduces current, 100x more selective for 1.7 over other Na+ channels.</p>
    Formula:C168H250N46O41S8
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3826.59

    Ref: TM-TP1680

  • AVLX-125
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    AVLX-125

    CAS:
    <p>AVLX-125 (UCCB01-125), a potent inhibitor of PSD-95 and PDZ domains, exhibits a dissociation constant (Kd) of 10 nM. It is utilized in researching inflammatory pain [1] [2].</p>
    Formula:C62H104N10O29
    Color and Shape:Solid
    Molecular weight:1453.54

    Ref: TM-TP2548

  • TRPA1 Antagonist 3
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    TRPA1 Antagonist 3

    CAS:
    <p>TRPA1 Antagonist 3 is a compound with photoswitchable properties that acts as an agonist on the TRPA1 channel, providing the ability for optical control.</p>
    Formula:C11H8ClN3
    Color and Shape:Solid
    Molecular weight:217.66

    Ref: TM-T40822

  • Vedroprevir
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    Vedroprevir

    CAS:
    <p>Vedroprevir (GS9451), a selective HCV NS3 protease inhibitor, targets genotype 1 HCV.</p>
    Formula:C45H60ClN7O9S
    Color and Shape:Solid
    Molecular weight:910.53

    Ref: TM-T35043

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    EVT-401

    <p>EVT-401 (P2X7 receptor antagonist-1), a purinergic P2X7 receptor antagonist, demonstrates efficacy in combating neuroinflammation [1].</p>
    Formula:C22H20F4N2O3
    Color and Shape:Solid
    Molecular weight:436.4

    Ref: TM-T74409

  • rac-trans-4-hydroxy Glyburide
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    rac-trans-4-hydroxy Glyburide

    CAS:
    <p>rac-trans-4-hydroxy Glyburide, a metabolite of glyburide, inhibits binding at SUR1/Kir6.2 sites with IC50 values of 0.95 and 100 nM.</p>
    Formula:C23H28ClN3O6S
    Color and Shape:Solid
    Molecular weight:510.0

    Ref: TM-T35635

  • CymitQuimica logo
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    Anticancer agent 108

    <p>Anticancer Agent 108 (Compound 3.10) serves as a potent P-gp inhibitor exhibiting considerable antitumor properties while maintaining reduced toxicity to both</p>
    Formula:C18H9NO5S2
    Color and Shape:Solid
    Molecular weight:383.4

    Ref: TM-T78693

  • 3-Aminopropylphosphinic acid
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    3-Aminopropylphosphinic acid

    CAS:
    <p>3-Aminopropylphosphinic acid (3-APPA) is a phosphonic analog of gamma-aminobutyric acid (GABA).</p>
    Formula:C3H10NO2P
    Color and Shape:Solid
    Molecular weight:123.092

    Ref: TM-T38438

  • Lei-Dab7
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    Lei-Dab7

    CAS:
    Selective KCa2.2 channel blocker with Kd 3.8 nM, >200-fold specificity, enhances LTP, convulsive in vivo.
    Formula:C141H236N46O39S6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3392.06

    Ref: TM-TP2007

  • JTS-653
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    JTS-653

    CAS:
    <p>JTS-653 is a potent TRPV1 antagonist, effective in reducing chronic pain unresponsive to NSAIDs.</p>
    Formula:C23H21F3N4O4
    Color and Shape:Solid
    Molecular weight:474.44

    Ref: TM-T41091

  • PDDHV
    Targetmol
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    PDDHV

    CAS:
    <p>PDDHV: a capsaicin-like vanilloid selective for rat TRPV1; induces Ca2+ uptake in neurons, EC50 of 70 nM.</p>
    Formula:C49H72O11
    Color and Shape:Solid
    Molecular weight:837.09

    Ref: TM-T37086

  • AQP4 (201-220)
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    AQP4 (201-220)

    CAS:
    <p>AQP4 (201-220) is the encephalitogenic epitope of AQP-4. AQP4 (201-220) can induce experimental autoimmune encephalomyelitis (EAE), characterized by midline brain lesions, retinal lesions, and lesions at the gray matter/white matter boundary of the spinal cord. AQP-4 is the target antigen in neuromyelitis optica.</p>
    Formula:C97H143N27O27S
    Color and Shape:Solid
    Molecular weight:2151.4

    Ref: TM-TP3213

  • 17R(18S)-EpETE
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    17R(18S)-EpETE

    CAS:
    <p>17R(18S)-EpETE: Oxylipin, eicosapentaenoic acid metabolite, activates BKCa channels, has negative chronotropic effects.</p>
    Formula:C20H30O3
    Color and Shape:Solid
    Molecular weight:318.457

    Ref: TM-T36215

  • N-Arachidonoyl Taurine
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    N-Arachidonoyl Taurine

    CAS:
    <p>N-Arachidonoyl taurine, an amino acid, activates TRPV1/TRPV4, is metabolized by lipoxygenase, and affects insulin secretion and calcium flux.</p>
    Formula:C22H37NO4S
    Color and Shape:Solid
    Molecular weight:411.6

    Ref: TM-T35918

  • 1-(1-Methyl-1h-pyrazol-4-yl)-ethanone
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    1-(1-Methyl-1h-pyrazol-4-yl)-ethanone

    CAS:
    <p>1-(1-Methyl-1h-pyrazol-4-yl)-ethanone is a high purity biochemical reagent that can be used in research related to life sciences.</p>
    Formula:C6H8N2O
    Purity:99.92%
    Color and Shape:Solid
    Molecular weight:124.14

    Ref: TM-TN9428

  • GsMTx4
    Targetmol
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    GsMTx4

    CAS:
    <p>GsMTx-4, mechanosensitive and stretch-activated ion channel inhibitor (CAS 1209500-46-8).</p>
    Formula:C185H273N49O45S6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:4095.84

    Ref: TM-TP1670

  • Fipronil sulfone
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    Fipronil sulfone

    CAS:
    Fipronil sulfone is an insecticide fipronil. Its metabolite fipronil sulphone is an inhibitor of rat ɑ1β2γ2L GABA(A) receptor.
    Formula:C12H4Cl2F6N4O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:453.14

    Ref: TM-T21071