Membrane Transporter/Ion Channel
Membrane transporter and ion channel inhibitors are compounds that block the function of proteins responsible for the transport of ions, nutrients, and other molecules across cell membranes. These inhibitors are crucial for studying the regulation of cellular homeostasis, signal transduction, and neurotransmission. Membrane transporter and ion channel inhibitors are also important in developing treatments for disorders such as epilepsy, cardiovascular diseases, and metabolic syndromes. At CymitQuimica, we provide a diverse selection of high-quality membrane transporter and ion channel inhibitors to support your research in physiology, neuroscience, and pharmacology.
Subcategories of "Membrane Transporter/Ion Channel"
- ABC(3 products)
- ATPase(92 products)
- Adiponectin receptor(5 products)
- CFTR(66 products)
- CGRP Receptor(55 products)
- Calcium Channel(578 products)
- Chloride channel(53 products)
- GABA Receptor(367 products)
- Monoamine Transporter(30 products)
- Monocarboxylate transporter(18 products)
- NKCC(2 products)
- NPC1L1(1 products)
- Na-K-Cl cotransporter(9 products)
- OAT(31 products)
- OCT(7 products)
- P-gp(56 products)
- Potassium Channel(319 products)
- Proton pump(42 products)
- SGLT(32 products)
- Sodium Channel(273 products)
- TRP/TRPV Channel(97 products)
Show 13 more subcategories
Found 2690 products for "Membrane Transporter/Ion Channel".
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PNU-140975
CAS:PNU-140975 is a bio-active chemical.Formula:C3H9N5O2Color and Shape:SolidMolecular weight:147.138CP-628006
CAS:CP-628006 is a small molecule CFTR potentiator that effectively restores ATP-dependent channel gating to G551D-CFTR, the mutant form found in cystic fibrosis.Formula:C32H35F3N2O2Color and Shape:SolidMolecular weight:536.639AChE/Aβ-IN-1
AChE/Aβ-IN-1 (compound 32) is a potent, orally active acetylcholinesterase (AChE) inhibitor with an IC50 of 86 nM and an NMDA receptor antagonist targeting theFormula:C20H25BrN4Color and Shape:SolidMolecular weight:401.34JTS-653
CAS:JTS-653 is a potent TRPV1 antagonist, effective in reducing chronic pain unresponsive to NSAIDs.Formula:C23H21F3N4O4Color and Shape:SolidMolecular weight:474.44DAA-1106
CAS:DAA-1106 is a potent and selective ligand for PBR, acting as a potent and selective agonist at the peripheral benzodiazepine receptor.Formula:C23H22FNO4Purity:99.54%Color and Shape:SolidMolecular weight:395.42Charybdotoxin
CAS:Specific inhibitor of the big conductance Ca2+-activated K+ channel.Formula:C176H277N57O55S7Purity:98%Color and Shape:SolidMolecular weight:4295.95Way 125971
CAS:Way 125971 is a bioactive chemcial.Formula:C22H28N4O5S2Color and Shape:SolidMolecular weight:492.61Sodium Channel inhibitor 5
Sodium Channel inhibitor5 (compound 7d) is a potent sodium channel inhibitor with an IC50 of 2.7 μM, playing a significant role in antiarrhythmic research.Formula:C24H23F3N4O2Color and Shape:SolidMolecular weight:456.17731AZD-3161
CAS:AZD-3161 is a sodium channel regulator for pain.Formula:C23H21F3N4O4Color and Shape:SolidMolecular weight:474.43(±)5(6)-DiHETE
CAS:Eicosapentaenoic acid is an ω-3 polyunsaturated fatty acid that is abundant in marine organisms and fish oils.Formula:C20H32O4Color and Shape:SolidMolecular weight:336.472ProTx II
CAS:Selective NaV1.7 inhibitor, alters activation, reduces current, 100x more selective for 1.7 over other Na+ channels.Formula:C168H250N46O41S8Purity:98%Color and Shape:SolidMolecular weight:3826.59Calcium Ionophore I
CAS:Calcium Ionophore I is a selective calcium ionophore. Primarily used in the fabrication of Ca2+-selective microelectrodes, it allows for the precise measurement of intracellular calcium levels in physiological and electrophysiological research.Formula:C38H72N2O8Color and Shape:Transparent LiquidMolecular weight:685Guangxitoxin 1E
CAS:Guangxitoxin 1E acts as a gating modifier since it shifts the voltage-dependence of Kv2.1 K+ currents towards depolarized potentials.Formula:C178H248N44O45S7Purity:98%Color and Shape:SolidMolecular weight:3948.61Vedroprevir
CAS:Vedroprevir (GS9451), a selective HCV NS3 protease inhibitor, targets genotype 1 HCV.Formula:C45H60ClN7O9SColor and Shape:SolidMolecular weight:910.53AmmTX3
KV4 channel blocker that inhibits A-type K+ current in mouse neurons; requires DPP6 and DPP10 for effect.Formula:C158H262N50O48S6Purity:98%Color and Shape:SolidMolecular weight:3822.47rac-trans-4-hydroxy Glyburide
CAS:rac-trans-4-hydroxy Glyburide, a metabolite of glyburide, inhibits binding at SUR1/Kir6.2 sites with IC50 values of 0.95 and 100 nM.Formula:C23H28ClN3O6SColor and Shape:SolidMolecular weight:510.0WAY-326766
CAS:WAY-326766 increases ion transport through mutant CFTR and can be used to alter the lifespan of eukaryotes.WAY-326766 can be used to treat cystic fibrosis (CF).Formula:C21H23N3O5Purity:99.87%Color and Shape:SolidMolecular weight:397.42P2X4 antagonist-3
P2X4 antagonist-3 (Compound 14c) is a P2X4 inhibitor with an IC50 value of 1.2 μM. It holds potential for research into neuroinflammation, chronic pain, and cancer progression.Formula:C19H20FN3O4Color and Shape:SolidMolecular weight:373.38α-Casozepine
CAS:α-Casozepine,Bioactive peptide from milk α-S1 casein. Binds GABA receptors. Anti-anxiety effects.Formula:C60H94N14O16Purity:99.81%Color and Shape:SolidMolecular weight:1267.47GaTx2
CAS:High-affinity ClC-2 blocker (KD ~50 pM), selective over other ClCs/CFTR/GABAC/CaCC/KV1.2; slows activation, no effect on open channels.Formula:C125H199N39O47S6Purity:98%Color and Shape:SolidMolecular weight:3192.54FD 12-9
CAS:FD 12-9, Anti-glioblastoma activity. is a flavonoid dimer, acts as a dual inhibitor of P-gp and BCRP, with EC50s of 285 nM and 0.9 nM, respectively.Formula:C51H47N3O11Purity:98%Color and Shape:SolidMolecular weight:877.93GpTx-1 TFA
GpTx-1 TFA is a polypeptide NaV1.7 sodium channel antagonist isolated from the venom of the Chilean spider Grammostola porter. It exhibits potent inhibitory activity on the NaV1.7 channel with an IC50 value of 10 nM, demonstrating excellent selectivity over NaV1.4 (IC50 = 0.301 μM) and NaV1.5 (IC50 = 4.20 μM) with >20-fold and >950-fold selectivity, respectively.Color and Shape:Odour Solid17R(18S)-EpETE
CAS:17R(18S)-EpETE: Oxylipin, eicosapentaenoic acid metabolite, activates BKCa channels, has negative chronotropic effects.Formula:C20H30O3Color and Shape:SolidMolecular weight:318.457(±)17-HETE
CAS:Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites.Formula:C20H32O3Color and Shape:SolidMolecular weight:320.473AZD0095
CAS:AZD0095 is a selective inhibitor of MCT4 with an IC50 of 1.3 nM.Formula:C27H32N8O2Purity:98.51%Color and Shape:SoildMolecular weight:500.6Ref: TM-T64378
1mg96.00€5mg205.00€1mL*10mM (DMSO)268.00€10mg334.00€25mg520.00€50mg750.00€100mg1,035.00€Huwentoxin-IV
CAS:Selective NaV1.7 blocker; also inhibits NaV1.2, 1.3; less effect on NaV1.4, 1.5. Binds to neurotoxin site, traps voltage sensor. IC50: 26-338 nM.Formula:C174H278N52O51S6Purity:98%Color and Shape:SolidMolecular weight:4106.79S-Bioallethrin
CAS:S-Bioallethrin is a pure S-form of Bioallethrin.Formula:C19H26O3Purity:98%Molecular weight:302.41GDC-0334
CAS:GDC-0334 is a TRPA1 antagonist useful in treatment TRPA1-mediated diseases, such as pain or asthma.Formula:C24H19F8N5O3SColor and Shape:SolidMolecular weight:609.5Lnd 623
CAS:Lnd 623 is an inotropic aminosteroid.Formula:C27H47NO6Color and Shape:SolidMolecular weight:481.674OD1
Activates rat Nav1.7, human Nav1.4, rat Nav1.6 (EC50: 7, 10, 47 nM); minimal on Nav1.2, 1.3, 1.5 (EC50 >3 μM); blocks fast inactivation; triggers pain.Formula:C308H466N90O95S8Purity:98%Color and Shape:SolidMolecular weight:7206.1Katacalcin
CAS:Katacalcin (PDN 21) is a potent plasma calcium-lowering peptide[1].Formula:C97H154N34O36S2Purity:98%Color and Shape:White PowderMolecular weight:2436.6Digoxigenin Monodigitoxoside
CAS:Digoxigenin monodigitoxoside is a cardiac glycoside metabolite of digoxin and a Na+/K+ ATPase inhibitor.Formula:C29H44O8Color and Shape:SolidMolecular weight:520.663NF864
CAS:NF864, a suramin analog, is a P2X1 receptor inhibitor.Formula:C57H28N6Na12O41S12Purity:98%Color and Shape:SolidMolecular weight:2113.5Anticonvulsant agent 9
Anticonvulsant agent 9 (compound 4f) is an activator of the α1β2γ2GABA_A receptor, with an EC50 value of 1.24 μM. It inhibits the inactivation of Nav1.2 channels and exhibits significant anticonvulsant activity.Formula:C22H24N4O2Color and Shape:SolidMolecular weight:376.45Iberiotoxin
CAS:Selective blocker of the big conductance Ca2+-activated K+ channel.Formula:C179H274N50O55S7Purity:98%Color and Shape:SolidMolecular weight:4230AHN-683
CAS:AHN-683 is a fluorescent ligand. It was used for peripheral-type benzodiazepine receptors.Formula:C42H32FN3O7Purity:98%Color and Shape:SolidMolecular weight:709.72TRPV1 activator-1
CAS:TRPV1 Activator-1 (Compound 8), a capsaicin analog featuring a modified neck structure, specifically interacts with the T551 residue [1].Formula:C18H27NO2SColor and Shape:SolidMolecular weight:321.48Volixibat
CAS:Volixibat, a selective inhibitor of the bile acid transporter, may treat non-alcoholic steatohepatitis.Formula:C38H51N3O12S2Purity:98%Color and Shape:SolidMolecular weight:805.95Tertiapin
CAS:Tertiapin (reduced) is a synthetic bee venom peptide characterized by disulfide bonds between Cys3-Cys14 and Cys5-Cys18. It acts as an inhibitor of inward-rectifying potassium channels (potassium Channel) and can also block the activity of calcium-activated large conductance potassium channels. Tertiapin (reduced) is utilized in research related to diseases such as rheumatoid arthritis and multiple sclerosis.Formula:C106H180N34O23S5Color and Shape:SolidMolecular weight:2459.1APETx2
CAS:ASIC3 inhibitor; IC50: 63 nM (rat), 175 nM (human). Blocks NaV1.8, NaV1.2; analgesic for acid/inflammatory pain.Formula:C196H280N54O61S6Purity:98%Color and Shape:SolidMolecular weight:4561.06GluN2B-NMDAR antagonist-1
Orally active GluN2B-NMDAR antagonist with neuroprotective properties for ischemic injury research.Formula:C26H23BrN2O2Color and Shape:SolidMolecular weight:475.38Apamin
CAS:Apamin: 18-amino acid bee venom peptide, blocks SK channels, anti-inflammatory, anti-fibrotic, strongly basic.Formula:C79H131N31O24S4Purity:98%Color and Shape:SolidMolecular weight:2027.34Ebio3
Ebio3 is a selective potassium ion channel (KCNQ2) inhibitor with an IC50 of 1.2 nM. It binds to the KCNQ2 channel via its hydrophobic tail, causing the inward movement of the S6 helix, which results in the closure of the internal gate. The inhibitory effect of Ebio3 is equally effective on pathogenic KCNQ2 mutants, such as R75C and I238L, reducing their outward current by approximately 80%. Ebio3 holds potential for research in neurological disorders like epilepsy.Formula:C19H23F2N3O2Color and Shape:SolidMolecular weight:363.4Verruculogen
CAS:Verruculogen, a toxin from Penicillium/Aspergillus, blocks Ca2+-K+ channels and halts mammalian M phase.Formula:C27H33N3O7Purity:98%Color and Shape:SolidMolecular weight:511.57ADWX 1
Potent KV1.3 blocker, IC50: 0.0019 nM; less effective on KV1.1. Curbs CD4+ T cell activation; eases rat multiple sclerosis model.Formula:C169H281N57O46S7Purity:98%Color and Shape:SolidMolecular weight:4071.86JYL-79
CAS:JYL-79 is an agonist of the vanilloid receptor.Formula:C26H36N2O4SColor and Shape:SolidMolecular weight:472.64LY393615
LY393615 (NCC1048) is a novel blocker of both neuronal Ca²⁺ (calcium) and Na⁺ (sodium) channels, exhibiting half-maximal inhibitory concentrations (IC₅₀) of 1.9Purity:98%Color and Shape:Odour SolidPDZ1 Domain inhibitor peptide
CAS:Novel cyclic peptide that disrupts interaction between GluR6 and PSD-95Formula:C38H61N9O11Purity:98%Color and Shape:SolidMolecular weight:819.94MRS4596
MRS4596: selective P2X4 blocker, IC50 1.38 μM, neuroprotective in stroke research.Formula:C21H14N5NaO3SColor and Shape:SolidMolecular weight:439.42AQP4 (205-215)
CAS:AQP4 (205-215) is a fragment of the water channel protein Aquaporin-4 (AQP4). This protein is an autoimmune antigen in optic neuromyelitis and, upon binding with CD40, is upregulated and presented in B cells. AQP4 is associated with neuromyelitis optica (NMO), an autoimmune inflammatory disease of the central nervous system (CNS).Formula:C48H75N13O17SColor and Shape:SolidMolecular weight:1138.25
