Membrane Transporter/Ion Channel
Membrane transporter and ion channel inhibitors are compounds that block the function of proteins responsible for the transport of ions, nutrients, and other molecules across cell membranes. These inhibitors are crucial for studying the regulation of cellular homeostasis, signal transduction, and neurotransmission. Membrane transporter and ion channel inhibitors are also important in developing treatments for disorders such as epilepsy, cardiovascular diseases, and metabolic syndromes. At CymitQuimica, we provide a diverse selection of high-quality membrane transporter and ion channel inhibitors to support your research in physiology, neuroscience, and pharmacology.
Subcategories of "Membrane Transporter/Ion Channel"
- ABC(3 products)
- ATPase(93 products)
- Adiponectin receptor(5 products)
- CFTR(64 products)
- CGRP Receptor(51 products)
- Calcium Channel(494 products)
- Chloride channel(49 products)
- GABA Receptor(336 products)
- Monoamine Transporter(23 products)
- Monocarboxylate transporter(17 products)
- NKCC(2 products)
- NPC1L1(3 products)
- Na-K-Cl cotransporter(8 products)
- OAT(27 products)
- OCT(7 products)
- P-gp(53 products)
- Potassium Channel(276 products)
- Proton pump(39 products)
- SGLT(30 products)
- Sodium Channel(202 products)
- TRP/TRPV Channel(93 products)
Show 13 more subcategories
Found 2280 products of "Membrane Transporter/Ion Channel"
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Lifastuzumab
CAS:<p>Sulfamethoxazole-NO (SMX-NO) is a SMX-NO derivative and is the primary immunogen for sulfonamide hypersensitivity reactions.</p>Purity:97% (SDS-PAGE); 99.5% (SEC-HPLC) - 97% (SDS-PAGE); 99.5% (SEC-HPLC)Color and Shape:LiquidMolecular weight:145.5 kDaAHN-683
CAS:<p>AHN-683 is a fluorescent ligand. It was used for peripheral-type benzodiazepine receptors.</p>Formula:C42H32FN3O7Purity:98%Color and Shape:SolidMolecular weight:709.72ATP Synthesis-IN-2
<p>ATP Synthesis-IN-2 (Compound 5) serves as a potent inhibitor of ATP synthesis activity, displaying significant antibacterial properties with an IC50 value of 0.</p>Color and Shape:Odour Solid4-oxo-2-Nonenal
CAS:<p>4-Hydroxy Nonenal and 4-oxo-2-Nonenal are lipid peroxidation byproducts, signaling oxidative stress and possibly causing mutagenesis.</p>Formula:C9H14O2Color and Shape:SolidMolecular weight:154.209AQP4 (201-220) TFA
<p>AQP4 (201-220) TFA is an encephalitogenic epitope of AQP-4. This compound can induce experimental autoimmune encephalomyelitis (EAE), characterized by midline brain lesions, retinal abnormalities, and lesions at the grey/white matter boundary of the spinal cord. AQP-4 is the target antigen in neuromyelitis optica.</p>Color and Shape:Odour SolidTRPV1 activator-2
CAS:<p>TRPV1 activator-2 (Compound 9), a capsaicin head analog, engages in targeted interactions with channel residues at the lipid-water interface [1].</p>Formula:C19H29NO3Color and Shape:SolidMolecular weight:319.44CHET3
CAS:<p>CHET3 is a highly selective allosteric activator for TASK-3-containing K2P channels. CHET3 has shown potent in vivo analgesic effects. Cost-effective and quality-assured.</p>Formula:C21H21N5O3SPurity:99.64% - >99.99%Color and Shape:SoildMolecular weight:423.49SC 4453
CAS:<p>SC 4453 is a digoxin analog and a cardiac glycoside derivative.</p>Formula:C41H64N2O12Color and Shape:SolidMolecular weight:776.965Chlorotoxin(linear)
<p>Chlorotoxin(linear): 36-amino-acid peptide from Egyptian scorpion venom, used in research as chloride channel blocker.</p>Formula:C158H256N52O48S11Purity:98%Color and Shape:SolidMolecular weight:4004.76GSK2332255B
CAS:<p>GSK2332255B: potent TRPC3/6 antagonist; IC50 5 nM (TRPC3), 4 nM (TRPC6); over 100-fold selectivity vs other Ca2+ channels.</p>Formula:C18H19ClFN3O3SColor and Shape:SolidMolecular weight:411.88BeKm-1
CAS:<p>Potent, selective hERG (KV11.1) blocker; doesn't affect 14 other K+ channels; extends QTc in rabbit heart dose-dependently.</p>Formula:C174H261N51O52S6Purity:98%Color and Shape:SolidMolecular weight:4091.65RuBi-GABA
CAS:<p>Ruthenium-bipyridine-triphenylphosphine caged GABA</p>Formula:C42H39F6N5O2P2RuPurity:98%Color and Shape:SolidMolecular weight:922.85-Tridecanol
CAS:<p>5-Tridecanol blocks ion flux in sodium channels.</p>Formula:C13H28OPurity:97.87%Color and Shape:SolidMolecular weight:200.36Vanzacaftor
CAS:<p>Vanzacaftor is a CFTR modulator improving protein processing and surface trafficking, restoring chloride transport and aiding cystic fibrosis therapy research.</p>Formula:C32H39N7O4SPurity:99.14%Color and Shape:SolidMolecular weight:617.76Riluzole-13C,15N2
CAS:<p>Riluzole-13C,15N2 (PK 26124-13C,15N2) is a 13C and 15N labeled form of Riluzole, a glutamate antagonist with anticonvulsant activity, inhibiting GABA uptake.</p>Formula:CC7H5F3OS15N2Color and Shape:SolidMolecular weight:237.18Anticancer agent 108
<p>Anticancer Agent 108 (Compound 3.10) serves as a potent P-gp inhibitor exhibiting considerable antitumor properties while maintaining reduced toxicity to both</p>Formula:C18H9NO5S2Color and Shape:SolidMolecular weight:383.4Neurotransmitter Receptor Compound Library
<p>A unique collection of 1513 neurotransmitter receptor compounds, can be used for HTS and HCS screening；</p>Color and Shape:Odour SolidChlorotoxin TFA
<p>Chlorotoxin TFA, a scorpion venom peptide, blocks chloride channels and has anti-cancer properties.</p>Formula:C160H250F3N53O49S11Color and Shape:SolidMolecular weight:4109.74GpTx-1 TFA
<p>GpTx-1 TFA is a polypeptide NaV1.7 sodium channel antagonist isolated from the venom of the Chilean spider Grammostola porter. It exhibits potent inhibitory activity on the NaV1.7 channel with an IC50 value of 10 nM, demonstrating excellent selectivity over NaV1.4 (IC50 = 0.301 μM) and NaV1.5 (IC50 = 4.20 μM) with >20-fold and >950-fold selectivity, respectively.</p>Color and Shape:Odour SolidASG-5ME
<p>ASG-5ME is a drug-antibody coupling targeting SLC44A4 that shows anti-tumor activity in xenograft models and may be used to study pancreatic and gastric cancer.</p>Purity:98.1% (SDS-PAGE); 98.5% (SEC-HPLC) - 98.1% (SDS-PAGE); 98.5% (SEC-HPLC)Color and Shape:LiquidMolecular weight:145.5 kDaAmpullosporin A
CAS:<p>Ampullosporin A is a peptaibol-type polypeptide isolated from the fungus Sepedonium ampullosporum (HKI-0053), exhibiting neuromodulatory activity. It inhibits hyperactivity induced by the NMDA receptor antagonist MK-801 and ameliorates social behavior abnormalities caused by subchronic ketamine treatment. Ampullosporin A modulates glutamate receptor activity without affecting dopamine D1 and D2 receptors.</p>Formula:C77H127N19O19Color and Shape:SolidMolecular weight:1622.95PtdIns-(1,2-dioctanoyl) (sodium salt)
CAS:<p>PtdIns phosphates, a minor membrane lipid fraction, are vital for cell signaling. Synthetic PtdIns-(1,2-dioctanoyl) has C8:0 fatty acids and high solubility.</p>Formula:C25H47NaO13PColor and Shape:SolidMolecular weight:609.602Homocarnosine
CAS:<p>Homocarnosine is an endogenous dipeptide in cerebral regions and cerebrospinal fluid.</p>Formula:C10H16N4O3Color and Shape:SolidMolecular weight:240.26Antidepressant agent 3
<p>Agent 3: orally active, antidepressant, anxiolytic, boosts performance and cognition.</p>Formula:C17H30ClN5O2SColor and Shape:SolidMolecular weight:403.97Tertiapin LQ
<p>Kir1.1 channel blocker, 250x selective; Kd: Kir1.1 (1.1 nM), Kir3.1/3.2 (274 nM), Kir3.1/3.4 (361 nM). Tertiapin-Q derivative.</p>Formula:C106H179N33O24S4Purity:98%Color and Shape:SolidMolecular weight:2428.03Flufiprole
CAS:<p>Flufiprole is used as a phenylpyrazole pesticide. It has enantioselective metabolism in human and rat liver microsomes.</p>Formula:C16H10Cl2F6N4OSColor and Shape:SolidMolecular weight:491.24(2R,3S,11bS)-Dihydrotetrabenazine
CAS:<p>(2R,3S,11bS)-Tetrabenazine impurity, VMAT inhibitor for movement disorders.</p>Formula:C19H29NO3Purity:99.29%Color and Shape:SolidMolecular weight:319.44Zoniporide
CAS:<p>Zoniporide (CP-597396) is an NHE-1 inhibitor that inhibits platelet swelling and can be used in the study of cardiovascular diseases.</p>Formula:C17H16N6OPurity:99.74%Color and Shape:SolidMolecular weight:320.35Solpecainol
CAS:<p>solpecainol is a sodium channel blocker used in the study of neurological and cardiovascular diseases.</p>Formula:C18H23NO3Purity:99.71%Color and Shape:SoildMolecular weight:301.38Cyclic ADP-ribose ammonium
<p>cADPR ammonium is a second messenger that boosts cytosolic calcium via Ryanodine receptors and TRPM2 channels.</p>Color and Shape:LiquidHomocarnosine TFA
<p>Homocarnosine TFA: brain-exclusive GABA-histidine dipeptide, neuronal, anticonvulsant, antioxidant, anti-inflammatory.</p>Formula:C12H17F3N4O5Color and Shape:SolidMolecular weight:354.28Ion Channel Targeted Library
<p>A unique collection of 931 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery;</p>Color and Shape:Odour SolidWithasomniferolide B
CAS:<p>Withasomniferolide B, a withanolide from Withania somnifera root, activates GABAA receptors.</p>Formula:C28H36O4Color and Shape:SolidMolecular weight:436.58Volixibat
CAS:<p>Volixibat, a selective inhibitor of the bile acid transporter, may treat non-alcoholic steatohepatitis.</p>Formula:C38H51N3O12S2Purity:98%Color and Shape:SolidMolecular weight:805.95GeX-2
CAS:<p>GeX-2 is a truncated analogue of αO-conotoxin. It has the ability to activate GABAB receptors and inhibit α9α10nAChR as well as CaV2.2 channels. Additionally, GeX-2 is effective in alleviating pain in a rat model of chronic constriction injury.</p>Formula:C103H169N43O27Color and Shape:SolidMolecular weight:2441.72Albanin A
<p>Albanin A is a useful organic compound for research related to life sciences and the catalog number is T124310.</p>Formula:C20H18O6Color and Shape:SolidMolecular weight:354.358Conantokin G TFA
<p>Conantokin G TFA, a 17-aa peptide, blocks NMDA receptors with 480 nM IC50 and is neuroprotective.</p>Formula:C90H139F3N26O46Color and Shape:SolidMolecular weight:2378.21AR-C141990 hydrochloride
CAS:<p>AR-C141990 HCl inhibits MCT-1 (pKi 7.6) and MCT-2 (pKi 6.6), and has immunosuppressive effects.</p>Formula:C26H29ClN4O4SColor and Shape:SolidMolecular weight:529.05CBP-1008
<p>CBP-1008 is a dual-ligand peptide-drug conjugate (PDC) with MMAE, targeting folate receptor (FRα) and TRPV6. It exhibits high binding affinity to FRα and low affinity to TRPV6. CBP-1008 shows antitumor activity and can be utilized for research in advanced solid tumors such as colorectal cancer, breast cancer, non-small cell lung cancer, ovarian cancer, adrenocortical carcinoma, and follicular dendritic cell sarcoma.</p>Color and Shape:Odour SolidGABAA receptor modulator-4
<p>GABAA receptor modulator-4 (Compound 4) acts as a negative allosteric modulator of the GABAA receptor. It inhibits the peak and steady-state currents mediated by the α1β3γ2 GABAA receptors, with an IC50 of 10 μM for both.</p>Formula:C15H17BrO4SColor and Shape:SolidMolecular weight:373.26(R)-IDHP
CAS:<p>(R)-IDHP, a salvia derivative, relaxes blood vessels by blocking calcium channels, aiding cardiovascular research.</p>Formula:C12H16O5Color and Shape:SolidMolecular weight:240.252,4,6-Tri-tert-butylphenol
CAS:<p>2,4,6-Tri-tert-butylphenol inhibits the Ca2+ ATPase activity of human red blood cell membranes and can be used in related research in the field of life sciences.</p>Formula:C18H30OPurity:99.55%Color and Shape:SolidMolecular weight:262.43Sinapine hydroxide
CAS:<p>Sinapine hydroxide from crucifer seeds has anti-inflammatory, anti-oxidant, anti-tumor properties, and inhibits AChE, aiding neurodegenerative research.</p>Formula:C16H25NO6Color and Shape:SolidMolecular weight:327.377Guangxitoxin 1E
CAS:<p>Guangxitoxin 1E acts as a gating modifier since it shifts the voltage-dependence of Kv2.1 K+ currents towards depolarized potentials.</p>Formula:C178H248N44O45S7Purity:98%Color and Shape:SolidMolecular weight:3948.61Phe-Met-Arg-Phe, amide
CAS:<p>Phe-Met-Arg-Phe amide activates K+ current in neurons (ED50=23 nM), co-localizes with neuropeptide Y in brain regions.</p>Formula:C29H42N8O4SPurity:98%Color and Shape:SolidMolecular weight:598.76NSC265473
CAS:<p>NSC265473 is an ABCG2 substrate.</p>Formula:C21H35N3O4SColor and Shape:SolidMolecular weight:425.58Nitrazolam
CAS:<p>Nitrazolam is a benzodiazepine compound that may exhibit central nervous system depressant properties similar to traditional benzodiazepine drugs by acting on the GABA receptors (GABA receptor). These effects include sedation, hypnosis, anxiolytic, and anticonvulsant activities.</p>Formula:C17H13N5O2Color and Shape:SolidMolecular weight:319.32Digoxigenin Monodigitoxoside
CAS:<p>Digoxigenin monodigitoxoside is a cardiac glycoside metabolite of digoxin and a Na+/K+ ATPase inhibitor.</p>Formula:C29H44O8Color and Shape:SolidMolecular weight:520.66318β-Glycyrrhetyl-3-O-sulfate
CAS:<p>18β-Glycyrrhetyl-3-O-sulfate (Glycyrrhetic acid 3-O-(hydrogen sulfate)), a major metabolite of Glycyrrhetinic acid (GA), serves as a potent inhibitor of type 2</p>Formula:C30H46O7SColor and Shape:SolidMolecular weight:550.75Chlorotoxin
CAS:<p>Chlorotoxin: 36-amino acid peptide from deathstalker scorpion venom; blocks small chloride channels.</p>Formula:C158H249N53O47S11Purity:98%Color and Shape:SolidMolecular weight:3995.71
