Membrane Transporter/Ion Channel
Membrane transporter and ion channel inhibitors are compounds that block the function of proteins responsible for the transport of ions, nutrients, and other molecules across cell membranes. These inhibitors are crucial for studying the regulation of cellular homeostasis, signal transduction, and neurotransmission. Membrane transporter and ion channel inhibitors are also important in developing treatments for disorders such as epilepsy, cardiovascular diseases, and metabolic syndromes. At CymitQuimica, we provide a diverse selection of high-quality membrane transporter and ion channel inhibitors to support your research in physiology, neuroscience, and pharmacology.
Subcategories of "Membrane Transporter/Ion Channel"
- ABC(3 products)
- ATPase(93 products)
- Adiponectin receptor(5 products)
- CFTR(64 products)
- CGRP Receptor(52 products)
- Calcium Channel(496 products)
- Chloride channel(49 products)
- GABA Receptor(337 products)
- Monoamine Transporter(23 products)
- Monocarboxylate transporter(17 products)
- NKCC(2 products)
- NPC1L1(3 products)
- Na-K-Cl cotransporter(8 products)
- OAT(27 products)
- OCT(7 products)
- P-gp(53 products)
- Potassium Channel(277 products)
- Proton pump(39 products)
- SGLT(30 products)
- Sodium Channel(202 products)
- TRP/TRPV Channel(93 products)
Show 13 more subcategories
Found 2293 products of "Membrane Transporter/Ion Channel"
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R 56865
CAS:R 56865 is a weak potential-operated channel inhibitor that inhibits the late sodium current in human isolated cardiomyocytes.Formula:C23H28FN3OSPurity:99.52%Color and Shape:SolidMolecular weight:413.55TC-I 2014
CAS:TC-I 2014 shows antiallodynic properties in pain models.Formula:C23H19F6N3OPurity:99.07%Color and Shape:SolidMolecular weight:467.41Riluzole hydrochloride
CAS:<p>Riluzole hydrochloride, an anticonvulsant Na+ channel blocker, inhibits GABA uptake (IC50: 43 µM).</p>Formula:C8H6ClF3N2OSPurity:99.76%Color and Shape:SolidMolecular weight:270.66KT-362 fumarate
CAS:<p>KT-362 fumarate, a novel antagonist of Ca, K, and Na channels, induces vasodilation and relaxes rabbit arterial strips.</p>Formula:C26H32N2O7SPurity:99.75% - 99.98%Color and Shape:SolidMolecular weight:516.61ZM 226600
CAS:<p>ZM 226600 is an ATP-sensitive potassium channel opener with an EC50 value of 500 nM. ZM226600 has an inhibitory effect on spontaneous bladder activity.</p>Formula:C16H14F3NO4SPurity:99.87%Color and Shape:SolidMolecular weight:373.35Leminoprazole
CAS:<p>Leminoprazole is an orally available H+,K(+)-ATPase inhibitor that protects gastric mucosal cells from various cellular damages.</p>Formula:C19H23N3OSPurity:99.08% - 99.56%Color and Shape:SolidMolecular weight:341.47PD-118057
CAS:<p>PD-118057, a potent hERG activator, may treat long QT syndrome and heart failure without hERG activity inhibition.</p>Formula:C21H17Cl2NO2Purity:99.16% - 99.97%Color and Shape:SolidMolecular weight:386.27Orphenadrine
CAS:<p>Orphenadrine is a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist that inhibits clonal HERG channels in a concentration-dependent manner,</p>Formula:C18H23NOPurity:98.91% - 99.11%Color and Shape:SolidMolecular weight:269.38ANO1-IN-1
CAS:<p>ANO1-IN-1 blocks ANO1/2 channels (IC50: 2.56/15.43 μM) and hinders glioma cell growth.</p>Formula:C18H28N2O2SPurity:99.66%Color and Shape:SolidMolecular weight:336.49BPDBA
CAS:BPDBA is an effective, selective, and non-competitive inhibitor of the betaine/GABA transporter (BGT-1), displaying inhibitory activity against human BGT-1 andFormula:C19H20Cl2N2OPurity:99.43% - 99.95%Color and Shape:SolidMolecular weight:363.28Coelenterazine h
CAS:<p>Coelenterazine H, a Ca2+ sensitive synthetic derivative, is a luminescent biomolecule used to measure Ca2+ changes.</p>Formula:C26H21N3O2Purity:99.49%Color and Shape:Yellow To Brownish PowderMolecular weight:407.46PF-06456384
CAS:PF-06456384 is a highly potent and selective NaV1.7 inhibitor with IC50 value of 0.01 nM.Formula:C35H32F3N7O3S2Purity:98%Color and Shape:SolidMolecular weight:719.8α,β-Methylene-ATP
CAS:<p>α,β-Methylene ATP，一种ATP的膦酸酯类似物，充当P2X3和P2X7受体的配体。该化合物对P2X1和P2X3表现出高选择性激动剂活性，而在P2X2, 4, 7受体上无活性。</p>Formula:C11H18N5O12P3Color and Shape:SolidMolecular weight:505.21VU6007477
CAS:<p>VU6007477: M1 PAM, EC50=230 nM, min. agonist activity, penetrates CNS, no seizure AEs.</p>Formula:C24H26N6O2Color and Shape:SolidMolecular weight:430.5BMS-199264 hydrochloride
CAS:<p>BMS-199264 hydrochloride is selective inhibitor of mitochondrial F1F0 ATP hydrolase,inhibit decline of ATP and myocardial necrosis during myocardial ischemia.</p>Formula:C26H32Cl2N4O4SPurity:99.86%Color and Shape:SolidMolecular weight:567.53Glibornuride
CAS:<p>Glibornuride is a blocker of ATP-sensitive K+ channel(pKi: 5.75).</p>Formula:C18H26N2O4SPurity:99.5%Color and Shape:SolidMolecular weight:366.48Piprofurol
CAS:<p>Piprofurol is used as a Calcium channel blocker.</p>Formula:C26H33NO6Purity:98%Color and Shape:SolidMolecular weight:455.54URAT1 inhibitor 6
CAS:<p>URAT1 inhibitor 6 (Compound 1h), with an IC50 of 35 nM for hURAT1, demonstrates 200-fold and 8-fold greater potency compared to Lesinurad and Benzbromarone,</p>Formula:C9H7BrN3NaO2S2Color and Shape:SolidMolecular weight:356.2RS 5773
CAS:<p>RS 5773 is a benzothiazepine derivative with antianginal effects.</p>Formula:C29H33ClN2O4SPurity:98%Color and Shape:SolidMolecular weight:541.1PF-05241328
CAS:PF-05241328 is an effective and selective inhibitor of human Nav1.7 voltage-dependent sodium channels (IC50: 31 nM).Formula:C19H21ClN4O4SPurity:98%Color and Shape:SolidMolecular weight:436.91VMAT2-IN-I HCl
CAS:<p>VMAT2-IN-I HCl is an inhibitor of vesicular monoamine transporter-2. It also has 15- fold greater affinity than GZ- 793A.</p>Formula:C25H32ClF4NO4Purity:98%Color and Shape:SolidMolecular weight:521.97(Rac)-AMG8379
CAS:<p>(Rac)-AMG8379 ((Rac)-AMG8380) is a racemate of AMG8379 which is an orally active and selective sulfonamide NaV1.7 antagonist.</p>Formula:C25H16ClF2N3O5SPurity:99.6%Color and Shape:SolidMolecular weight:543.93PF-4778574
CAS:<p>PF-4778574 is a positive AMPA receptor allosteric modulation (EC50: 45 to 919 nM in different cells).</p>Formula:C19H22N2O3S2Purity:98%Color and Shape:SolidMolecular weight:390.52GNE-0723
CAS:<p>GNE-0723 is a selective positive allosteric modulator of the NMDA receptor, GluN2A.blood-brain barrier (BBB) and Dravet syndrome and Alzheimer's disease (AD).</p>Formula:C16H8ClF6N5OSPurity:97.29% - 99.91%Color and Shape:SolidMolecular weight:467.78PPADS tetrasodium
CAS:<p>PPADS tetrasodiuma is a P2X receptor antagonist and an inhibitor of the inverse mode of Na/Ca²⁺ exchange in guinea pig airway smooth muscle.</p>Formula:C14H10N3Na4O12PS2Purity:95% - ≥95%Color and Shape:SolidMolecular weight:599.3GDC-0310
CAS:<p>GDC-0310 is a selective, orally available Nav1.7 inhibitor with an IC50 of 0.6 nM for human Nav1.7, suitable for pain research.</p>Formula:C25H29Cl2FN2O4SPurity:99.877%Color and Shape:SolidMolecular weight:543.48Chromanol 293B
CAS:slow delayed rectifier K+ current (IKs) blockerFormula:C15H20N2O4SPurity:98%Color and Shape:SolidMolecular weight:324.4α,β-Methylene ATP trisodium
CAS:α,β-Methylene ATP trisodium is a ligand of P2X3 and P2X7 receptor.Formula:C11H15N5Na3O12P3Purity:99.66%Color and Shape:SolidMolecular weight:571.15KVI-020
CAS:<p>KVI-020: oral Kv1.5 blocker (IC50: 480nM), hERG inhibitor (IC50: 15100nM), potent antiarrhythmic for AF studies.</p>Formula:C20H25N3O5SColor and Shape:SolidMolecular weight:419.49CGP 55845 hydrochloride
CAS:<p>CGP55845 hydrochloride is a potent and selective GABAB receptor antagonist with an IC 50 of 6 nM which can be used in neurological research [1] [2].</p>Formula:C18H23Cl3NO3PColor and Shape:SolidMolecular weight:438.71ZM 260384
CAS:<p>ZM 260384 is a potassium channel opener.</p>Formula:C15H11F4N3O4Color and Shape:SolidMolecular weight:373.26Lingdolinurad
CAS:<p>Lingdolinurad is a uric acid transporter protein inhibitor targeting hURAT1 for the study of hyperuricemia or gout.</p>Formula:C17H12BrN3O2Purity:96.26%Color and Shape:SolidMolecular weight:370.2(R)-Elexacaftor
CAS:<p>(R)-Elexacaftor (compound 37) is the enantiomer of Elexacaftor (compound 1). (R)-Elexacaftor is a CFTR modulator with an EC50 of 0.29 μM for CFTR dF508.</p>Formula:C26H34F3N7O4SPurity:98.991%Color and Shape:SolidMolecular weight:597.65Aneratrigine
CAS:<p>Aneratrigine is a blocker of the sodium channel protein type 9 subunit alpha, utilized in research on neuropathic pain diseases [1].</p>Formula:C19H20ClF2N5O2S2Purity:98%Color and Shape:SolidMolecular weight:487.97DPO-1
CAS:<p>DPO-1 可以高效抑制电压门控钾离子通道Kv1.5，也可以阻断超快速延迟整流钾电流。它能够预防房性心律失常。</p>Formula:C22H29OPPurity:99.78%Color and Shape:SolidMolecular weight:340.44Kv3 modulator 4
CAS:<p>Kv3 modulator 4 is a Kv3.1 (pEC50=5.45) and Kv3.2 modulator .Cyclobutyl structure.</p>Formula:C20H24N2O4Purity:98%Color and Shape:SolidMolecular weight:356.42Linaprazan
CAS:<p>Linaprazan (AZD0865) inhibits gastric H+,K+-ATPase by K+-competitive binding with an IC50 of 1.0 μM.</p>Formula:C21H26N4O2Purity:99.54%Color and Shape:SolidMolecular weight:366.46CP-409092
CAS:<p>CP-409092 is a partial GABAA receptor agonist. It has anti-anxiety activity.</p>Formula:C17H19N3O2Purity:98%Color and Shape:SolidMolecular weight:297.35(R)-3,4-DCPG
CAS:<p>AMPA receptor antagonist with weak activity at NMDA receptors and little activity at kainate receptors</p>Formula:C10H9NO6Purity:98%Color and Shape:SolidMolecular weight:239.18Sudoterb free base
CAS:<p>Sudoterb free base (Sudoterb) , also known as LL3858, is an anti-tubercular drug candidate.</p>Formula:C29H28F3N5OPurity:97.26% - 98.85%Color and Shape:SolidMolecular weight:519.56OADS
CAS:<p>OADS is an inhibitor of ClC-ec1 with low micromolar affinity. OADS has no specific effect on a CLC channel (ClC-1).</p>Formula:C30H42N2O8S2Color and Shape:SolidMolecular weight:622.79CP 154526
CAS:<p>CRF1 receptor antagonist</p>Formula:C23H33ClN4Purity:98%Color and Shape:SolidMolecular weight:400.99Dasolampanel etibutil
CAS:<p>Dasolampanel etibutil is a novel selective antagonist of ionotropic glutamate receptor 5 (iGluR5).</p>Formula:C23H32ClN5O3Color and Shape:SolidMolecular weight:461.98Potassium Channel Activator 1
CAS:<p>Potassium Channel Activator 1 aids treatment of ADHD, schizophrenia, and mood disorders by targeting the dopaminergic system.</p>Formula:C19H23N3O3Purity:99.86%Color and Shape:SolidMolecular weight:341.4UBP316
CAS:GluR5-containing kainate receptor antagonistFormula:C20H19N3O6SPurity:98%Color and Shape:SolidMolecular weight:429.45Naltiazem
CAS:<p>Naltiazem, a calcium channel antagonist, is used potentially for the treatment of arrhythmias, hypertension and myocardial infarction.</p>Formula:C26H28N2O4SPurity:98%Color and Shape:SolidMolecular weight:464.58Xeniafaraunol A
CAS:<p>Xeniafaraunol A (compound 31) is a potent inhibitor of the transient receptor potential melastatin 7 (TRPM7) channel [1].</p>Formula:C20H28O2Color and Shape:SolidMolecular weight:300.44TROX-1
CAS:<p>TROX-1 is the activation state-dependent Cav2 channel antagonist.</p>Formula:C22H16ClFN6OPurity:98%Color and Shape:SolidMolecular weight:434.85MK-2295
CAS:<p>MK-2295 is a potent TRPV1 antagonist. MK-2295 can be used in studies about the treatment of chronic pain.</p>Formula:C27H31FN6O2Purity:98.83% - 99.44%Color and Shape:SolidMolecular weight:490.57TRPV2-selective blocker 1
CAS:<p>TRPV2-selective blocker 1 (compound IV2-1) is a selective inhibitor of the TRPV2 channel, exhibiting an IC50 value of 6.3 μM.</p>Formula:C15H18OS2Color and Shape:SolidMolecular weight:278.43
