Membrane Transporter/Ion Channel
Membrane transporter and ion channel inhibitors are compounds that block the function of proteins responsible for the transport of ions, nutrients, and other molecules across cell membranes. These inhibitors are crucial for studying the regulation of cellular homeostasis, signal transduction, and neurotransmission. Membrane transporter and ion channel inhibitors are also important in developing treatments for disorders such as epilepsy, cardiovascular diseases, and metabolic syndromes. At CymitQuimica, we provide a diverse selection of high-quality membrane transporter and ion channel inhibitors to support your research in physiology, neuroscience, and pharmacology.
Subcategories of "Membrane Transporter/Ion Channel"
- ABC(3 products)
- ATPase(92 products)
- Adiponectin receptor(5 products)
- CFTR(66 products)
- CGRP Receptor(55 products)
- Calcium Channel(578 products)
- Chloride channel(53 products)
- GABA Receptor(367 products)
- Monoamine Transporter(30 products)
- Monocarboxylate transporter(18 products)
- NKCC(2 products)
- NPC1L1(1 products)
- Na-K-Cl cotransporter(9 products)
- OAT(31 products)
- OCT(7 products)
- P-gp(56 products)
- Potassium Channel(318 products)
- Proton pump(42 products)
- SGLT(32 products)
- Sodium Channel(273 products)
- TRP/TRPV Channel(97 products)
Show 13 more subcategories
Found 2690 products for "Membrane Transporter/Ion Channel".
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Linoleic Acid Amide
CAS:Linoleic Acid Amide (Linoleamide) is derived from linoleic acid and regulates Ca2+ flux by inhibiting the sarco/endoplasmic reticulum Ca2+-ATPase.Formula:C18H33NOPurity:98.41%Color and Shape:Yellow SolidMolecular weight:279.46Resolvin D2 methyl ester
CAS:RvD2 is an anti-inflammatory lipid made from docosahexaenoic acid by 15- and 5-lipoxygenase. Its methyl ester may serve as a prodrug.Formula:C23H34O5Color and Shape:SolidMolecular weight:390.52α,β-Methylene-ATP dilithium
CAS:α,β-Methylene ATP dilithium, a phosphonic analog of ATP, serves as a ligand for P2X3 and P2X7 receptors.Formula:C11H16Li2N5O12P3Color and Shape:SolidMolecular weight:517.07GeX-2
CAS:GeX-2 is a truncated analogue of αO-conotoxin. It has the ability to activate GABAB receptors and inhibit α9α10nAChR as well as CaV2.2 channels. Additionally, GeX-2 is effective in alleviating pain in a rat model of chronic constriction injury.Formula:C103H169N43O27Color and Shape:SolidMolecular weight:2441.72Katacalcin
CAS:Katacalcin (PDN 21) is a potent plasma calcium-lowering peptide[1].Formula:C97H154N34O36S2Purity:98%Color and Shape:White PowderMolecular weight:2436.6Mesoridazine free base
CAS:Mesoridazine (thioridazine EP impurity B) is a phenothiazine antipsychotic with effects similar to chlorpromazine.Formula:C21H26N2OS2Color and Shape:SolidMolecular weight:386.57LY-466195
CAS:LY-466195 is a competitive antagonist of GLUK5 receptor.Formula:C16H24F2N2O4Color and Shape:SolidMolecular weight:346.37Cyclocreatine
CAS:Cyclocreatine, a creatine analogue and substrate for creatine kinase, inhibits creatine metabolism and prostate cancer cell proliferation.Formula:C5H9N3O2Purity:99.86%Color and Shape:White SolidMolecular weight:143.14Tariquidar dimesylate
CAS:Tariquidar, a non-competitive P-glycoprotein inhibitor, may help combat cancer drug resistance.Formula:C80H94N8O25S4Purity:98%Color and Shape:SolidMolecular weight:1695.9GpTx-1 TFA
GpTx-1 TFA is a polypeptide NaV1.7 sodium channel antagonist isolated from the venom of the Chilean spider Grammostola porter. It exhibits potent inhibitory activity on the NaV1.7 channel with an IC50 value of 10 nM, demonstrating excellent selectivity over NaV1.4 (IC50 = 0.301 μM) and NaV1.5 (IC50 = 4.20 μM) with >20-fold and >950-fold selectivity, respectively.Color and Shape:Odour SolidATP Synthesis-IN-2
ATP Synthesis-IN-2 (Compound 5) serves as a potent inhibitor of ATP synthesis activity, displaying significant antibacterial properties with an IC50 value of 0.Color and Shape:Odour SolidN-Oleoyl Glutamine
CAS:N-Oleoyl Glutamine (Oleoyl-L-glutamine) antagonizes TRPV1 of the transient receptor potential (TRP) calcium channel.Formula:C23H42N2O4Purity:99.61%Color and Shape:SolidMolecular weight:410.59AR-C141990 hydrochloride
CAS:AR-C141990 HCl inhibits MCT-1 (pKi 7.6) and MCT-2 (pKi 6.6), and has immunosuppressive effects.Formula:C26H29ClN4O4SColor and Shape:SolidMolecular weight:529.05NT 13
CAS:NT 13 is a partial N-methyl-D-aspartate receptor (NMDAR) agonist used in the study of depression, anxiety, and other related diseases.Formula:C18H30N4O7Purity:98%Color and Shape:SolidMolecular weight:414.45Dihydroisopimaric acid
CAS:Dihydroisopimaric acid opens BKαβ1 channels - large Ca²⁺-activated K⁺ conductors, verified by whole-cell voltage clamp.Formula:C20H32O2Color and Shape:SolidMolecular weight:304.47Chlorotoxin
CAS:Chlorotoxin: 36-amino acid peptide from deathstalker scorpion venom; blocks small chloride channels.Formula:C158H249N53O47S11Purity:98%Color and Shape:SolidMolecular weight:3995.71(Rac)-Tezacaftor
CAS:(Rac)-Tezacaftor, a racemate, corrects F508del CFTR for cystic fibrosis research.Formula:C26H27F3N2O6Color and Shape:SolidMolecular weight:520.5Lyso-Globotriaosylceramide (d18:1)
CAS:Lyso-Gb3, lacking fatty acyl, binds Stx1 with cholesterol and phosphatidylcholine, not Stx2; lowers neutrophil viability; accumulates in Fabry disease.Formula:C36H67NO17Color and Shape:SolidMolecular weight:785.922(S)-(+)-Docosahexaenyl-2'-hydroxy-1'-propylamide
(S)-(+)-Docosahexaenyl-2'-hydroxy-1'-propylamide (N-Docosahexacnoylethanolamide(22:6)) is a homologue of dehydroepiandrosterone (DHEA). This compound can block Shaker-related voltage-gated potassium channels and inhibits Kv1.2 K+ currents with an IC50 value of 1.5 μM.Color and Shape:Odour SolidP-gp inhibitor 15
P-gp Inhibitor 15 (compound 7a), a nonsubstrate inhibitor of P-glycoprotein (Pgp), inhibits Pgp-ATPase activity and interferes with Pgp-mediated Rhodamine123Formula:C35H60N2O4Color and Shape:SolidMolecular weight:572.86Conantokin G
CAS:GluN2B-specific NMDA receptor blocker; IC50=480 nM in neurons, ~300 nM in oocytes; neuroprotective.Formula:C88H138N26O44Purity:98%Color and Shape:SolidMolecular weight:2264.21Kurtoxin
Kurtoxin is a selective Cav3 (T-type) voltage-gated Ca2+ channel gating inhibitor, exhibiting a dissociation constant (Kd) of 15 nM for the Cav3.1 (α1G T-type)Formula:C324H478N94O90S8Purity:98%Color and Shape:SolidMolecular weight:7386.36CALP3
CAS:Cell-permeable CaM agonist, binds EF-hand, activates phosphodiesterase without Ca2+, inhibits Ca2+ toxicity, IC50=33μM.Formula:C44H68N10O9Purity:98%Color and Shape:SolidMolecular weight:881.08UK-59811 hydrochloride
CAS:UK-59811 hydrochloride, Br-dihydropyridine derivative, blocks Ca V Ab channels in bacteria, IC50: 194 nM.Formula:C22H30BrClN2O5Color and Shape:SolidMolecular weight:517.85Sulcardine 2HCl
CAS:Sulcardine 2HCl is a multi-ion channel blocker that blocks the properties of hERG and hNav1.5 channels and can be used to study atrial fibrillation.Formula:C24H35Cl2N3O4SPurity:98.85% - 99.33%Color and Shape:SolidMolecular weight:532.523Volixibat
CAS:Volixibat, a selective inhibitor of the bile acid transporter, may treat non-alcoholic steatohepatitis.Formula:C38H51N3O12S2Purity:98%Color and Shape:SolidMolecular weight:805.95Roquefortine C
CAS:Roquefortine C is a fungal cyclopeptide isolated from Penicillium roquefortii, activates P-gp and also inhibits P450-3A and other haemoproteinsFormula:C22H23N5O2Purity:98%Color and Shape:SolidMolecular weight:389.45Thalidomide-O-Triazole-C4-amino
CAS:Thalidomide-O-Triazole-C4-amino is an E3 ubiquitin ligase ligand-linker conjugate (E3 Ligase Ligand-linker conjugate) designed for the synthesis of aTAG 4531.Formula:C20H22N6O5Color and Shape:SolidMolecular weight:426.436-FAM-AEEAC-SHK TFA
6-FAM-AEEAC-SHK TFA, a peptide neurotoxin derived from Stichodactyla helianthus and conjugated with a fluorescent marker, selectively blocks voltage-gated potassium channels (kv1.1 and kv1.2). By prolonging action potentials, it interferes with neural signal conduction, making it valuable in neuroscience research.Formula:C196H295N55O57S7·xCHF3O2Color and Shape:SolidMolecular weight:4558.23 (free acid)Jingzhaotoxin III
CAS:NaV1.5 channels blockerFormula:C174H241N47O46S6Purity:98%Color and Shape:SolidMolecular weight:3919.47Cavα2δ-IN-1
CAS:Cavα2δ-IN-1 demonstrates exceptional specificity for voltage-gated calcium channels Cavα2δ-1 (with a Ki value of 6 nM), in comparison to Cavα2δ-2 (with a KiFormula:C18H27N5OColor and Shape:SolidMolecular weight:329.448Agitoxin-2
CAS:Potent Shaker K+ channel blocker (Ki = 0.64 nM). Also inhibits Kv1.3, Kv1.6 and Kv1.1 K+ channels (Ki values are 4, 37 and 44 pM respectively).Formula:C169H278N54O48S8Purity:98%Color and Shape:SolidMolecular weight:4090.87WAY-326766
CAS:WAY-326766 increases ion transport through mutant CFTR and can be used to alter the lifespan of eukaryotes.WAY-326766 can be used to treat cystic fibrosis (CF).Formula:C21H23N3O5Purity:99.87%Color and Shape:SolidMolecular weight:397.42α-Casozepine
CAS:α-Casozepine,Bioactive peptide from milk α-S1 casein. Binds GABA receptors. Anti-anxiety effects.Formula:C60H94N14O16Purity:99.81%Color and Shape:SolidMolecular weight:1267.47AChE/Aβ-IN-2
AChE/Aβ-IN-2 (compound 33) is a powerful, orally active acetylcholinesterase (AChE) inhibitor with an IC50 of 135 nM.Formula:C20H25ClN4Color and Shape:SolidMolecular weight:356.89Halazone
CAS:Halazone (Pantocid) is fine white powder with an odor of chlorine. It has been widely used to disinfect drinking water.Formula:C7H5Cl2NO4SPurity:98.64%Color and Shape:SolidMolecular weight:270.09AZD0095
CAS:AZD0095 is a selective inhibitor of MCT4 with an IC50 of 1.3 nM.Formula:C27H32N8O2Purity:98.51%Color and Shape:SoildMolecular weight:500.6Ref: TM-T64378
1mg96.00€5mg205.00€1mL*10mM (DMSO)268.00€10mg334.00€25mg520.00€50mg750.00€100mg1,035.00€P-gp inhibitor 13
P-gp Inhibitor 13, a P-glycoprotein antagonist, can counteract paclitaxel resistance in A2780/T cells, proving valuable for advanced acute myeloid leukemiaFormula:C32H34O8Color and Shape:SolidMolecular weight:546.61TRPA1 Antagonist 3
CAS:TRPA1 Antagonist 3 is a compound with photoswitchable properties that acts as an agonist on the TRPA1 channel, providing the ability for optical control.Formula:C11H8ClN3Color and Shape:SolidMolecular weight:217.66EVT-401
EVT-401 (P2X7 receptor antagonist-1), a purinergic P2X7 receptor antagonist, demonstrates efficacy in combating neuroinflammation [1].Formula:C22H20F4N2O3Color and Shape:SolidMolecular weight:436.4Allatostatin II
CAS:Allatostatin II is an Inhibitors of juvenile hormone synthesis in insects.Formula:C49H74N14O13Purity:98%Color and Shape:SolidMolecular weight:1067.2BeKm-1
CAS:Potent, selective hERG (KV11.1) blocker; doesn't affect 14 other K+ channels; extends QTc in rabbit heart dose-dependently.Formula:C174H261N51O52S6Purity:98%Color and Shape:SolidMolecular weight:4091.65RuBi-GABA
CAS:Ruthenium-bipyridine-triphenylphosphine caged GABAFormula:C42H39F6N5O2P2RuPurity:98%Color and Shape:SolidMolecular weight:922.8Huwentoxin I
CAS:Huwentoxin I (HWTX-I) is a peptide toxin that targets and inhibits both voltage-gated sodium channels and N-type calcium channels.Formula:C161H246N48O44S6Purity:98%Color and Shape:SolidMolecular weight:3750.36Phe-Met-Arg-Phe amide trifluoroacetate
CAS:Phe-met-arg-phe amide trifluoroacetate is an activator of K+ current with an ED50 of 23nm on the fundus nerve.Formula:C33H44F6N8O8SPurity:98%Color and Shape:SolidMolecular weight:826.81Elgodipine
CAS:Elgodipine decreases angina severity, inhibits muscle growth, and is voltage-sensitive, showing promise for angina treatment.Formula:C29H33FN2O6Purity:99.84% - 99.98%Color and Shape:SolidMolecular weight:524.58Apamin
CAS:Apamin: 18-amino acid bee venom peptide, blocks SK channels, anti-inflammatory, anti-fibrotic, strongly basic.Formula:C79H131N31O24S4Purity:98%Color and Shape:SolidMolecular weight:2027.34Verruculogen
CAS:Verruculogen, a toxin from Penicillium/Aspergillus, blocks Ca2+-K+ channels and halts mammalian M phase.Formula:C27H33N3O7Purity:98%Color and Shape:SolidMolecular weight:511.5717(S)-HETE
CAS:17(S)-HETE is an arachidonic acid metabolite generated via the CYP450 pathway. 17(S)-HETE acts as an allosteric activator of CYP450 1B1 and an ATPase inhibitor.Formula:C20H32O3Color and Shape:Transparent LiquidMolecular weight:320.47Chlorotoxin TFA
Chlorotoxin TFA, a scorpion venom peptide, blocks chloride channels and has anti-cancer properties.Formula:C160H250F3N53O49S11Color and Shape:SolidMolecular weight:4109.74
