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Membrane Transporter/Ion Channel

Membrane Transporter/Ion Channel

Membrane transporter and ion channel inhibitors are compounds that block the function of proteins responsible for the transport of ions, nutrients, and other molecules across cell membranes. These inhibitors are crucial for studying the regulation of cellular homeostasis, signal transduction, and neurotransmission. Membrane transporter and ion channel inhibitors are also important in developing treatments for disorders such as epilepsy, cardiovascular diseases, and metabolic syndromes. At CymitQuimica, we provide a diverse selection of high-quality membrane transporter and ion channel inhibitors to support your research in physiology, neuroscience, and pharmacology.

Subcategories of "Membrane Transporter/Ion Channel"

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Found 2280 products of "Membrane Transporter/Ion Channel"

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  • Mesoridazine free base
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    Mesoridazine free base

    CAS:
    <p>Mesoridazine (thioridazine EP impurity B) is a phenothiazine antipsychotic with effects similar to chlorpromazine.</p>
    Formula:C21H26N2OS2
    Color and Shape:Solid
    Molecular weight:386.57

    Ref: TM-T3086L

  • Resolvin D2 methyl ester
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    Resolvin D2 methyl ester

    CAS:
    <p>RvD2 is an anti-inflammatory lipid made from docosahexaenoic acid by 15- and 5-lipoxygenase. Its methyl ester may serve as a prodrug.</p>
    Formula:C23H34O5
    Color and Shape:Solid
    Molecular weight:390.52

    Ref: TM-T37169

  • Verruculogen
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    Verruculogen

    CAS:
    <p>Verruculogen, a toxin from Penicillium/Aspergillus, blocks Ca2+-K+ channels and halts mammalian M phase.</p>
    Formula:C27H33N3O7
    Purity:98%
    Color and Shape:White Powder
    Molecular weight:511.57

    Ref: TM-T13297

  • Chlorotoxin
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    Chlorotoxin

    CAS:
    <p>Chlorotoxin: 36-amino acid peptide from deathstalker scorpion venom; blocks small chloride channels.</p>
    Formula:C158H249N53O47S11
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3995.71

    Ref: TM-TP1431

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    ATP Synthesis-IN-2

    <p>ATP Synthesis-IN-2 (Compound 5) serves as a potent inhibitor of ATP synthesis activity, displaying significant antibacterial properties with an IC50 value of 0.</p>
    Color and Shape:Odour Solid

    Ref: TM-T82944

  • Bendroflumethiazide
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    Bendroflumethiazide

    CAS:
    <p>Bendroflumethiazide (Naturetin) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p810)</p>
    Formula:C15H14F3N3O4S2
    Purity:98% - >99.99%
    Color and Shape:Crystals From Dioxane Solid
    Molecular weight:421.41

    Ref: TM-T1204

  • 3-Aminopropylphosphonic Acid
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    3-Aminopropylphosphonic Acid

    CAS:
    <p>3-aminopropylphosphonic acid (3-APPA) is a phosphonic analog of GABA that acts as a partial agonist of GABAB receptors (IC50 = 1.5 μM in a radioligand binding</p>
    Formula:C3H10NO3P
    Purity:99.84%
    Color and Shape:Light Yellow Liquid
    Molecular weight:139.09

    Ref: TM-T38205

  • N-Arachidonoyl Taurine
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    N-Arachidonoyl Taurine

    CAS:
    <p>N-Arachidonoyl taurine, an amino acid, activates TRPV1/TRPV4, is metabolized by lipoxygenase, and affects insulin secretion and calcium flux.</p>
    Formula:C22H37NO4S
    Color and Shape:Solid
    Molecular weight:411.6

    Ref: TM-T35918

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    P-gp inhibitor 13

    <p>P-gp Inhibitor 13, a P-glycoprotein antagonist, can counteract paclitaxel resistance in A2780/T cells, proving valuable for advanced acute myeloid leukemia</p>
    Formula:C32H34O8
    Color and Shape:Solid
    Molecular weight:546.61

    Ref: TM-T78974

  • AR-C141990 hydrochloride
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    AR-C141990 hydrochloride

    CAS:
    <p>AR-C141990 HCl inhibits MCT-1 (pKi 7.6) and MCT-2 (pKi 6.6), and has immunosuppressive effects.</p>
    Formula:C26H29ClN4O4S
    Color and Shape:Solid
    Molecular weight:529.05

    Ref: TM-T39767

  • 12,14-Dichlorodehydroabietic acid
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    12,14-Dichlorodehydroabietic acid

    CAS:
    <p>12,14-Dichlorodehydroabietic acid activates BK channels, blocks GABA A receptors, and increases calcium and neurotransmitter release.</p>
    Formula:C20H26Cl2O2
    Color and Shape:Solid
    Molecular weight:369.33

    Ref: TM-T40750

  • Volixibat
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    Volixibat

    CAS:
    <p>Volixibat, a selective inhibitor of the bile acid transporter, may treat non-alcoholic steatohepatitis.</p>
    Formula:C38H51N3O12S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:805.95

    Ref: TM-T17236

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    Idactamab

    CAS:
    <p>Idactamab (INT-001) is a monoclonal antibody to the human amino acid transport protein ASCT2.</p>
    Purity:> 95%
    Color and Shape:Liquid
    Molecular weight:146.2 kDa

    Ref: TM-T77385

  • Phe-Met-Arg-Phe, amide
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    Phe-Met-Arg-Phe, amide

    CAS:
    <p>Phe-Met-Arg-Phe amide activates K+ current in neurons (ED50=23 nM), co-localizes with neuropeptide Y in brain regions.</p>
    Formula:C29H42N8O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:598.76

    Ref: TM-TP1858

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    AChE/Aβ-IN-1

    <p>AChE/Aβ-IN-1 (compound 32) is a potent, orally active acetylcholinesterase (AChE) inhibitor with an IC50 of 86 nM and an NMDA receptor antagonist targeting the</p>
    Formula:C20H25BrN4
    Color and Shape:Solid
    Molecular weight:401.34

    Ref: TM-T79569

  • rac-trans-4-hydroxy Glyburide
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    rac-trans-4-hydroxy Glyburide

    CAS:
    <p>rac-trans-4-hydroxy Glyburide, a metabolite of glyburide, inhibits binding at SUR1/Kir6.2 sites with IC50 values of 0.95 and 100 nM.</p>
    Formula:C23H28ClN3O6S
    Color and Shape:Solid
    Molecular weight:510.0

    Ref: TM-T35635

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    Jingzhaotoxin III

    CAS:
    <p>NaV1.5 channels blocker</p>
    Formula:C174H241N47O46S6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3919.47

    Ref: TM-TP2263

  • Dihydroisopimaric acid
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    Dihydroisopimaric acid

    CAS:
    <p>Dihydroisopimaric acid opens BKαβ1 channels - large Ca²⁺-activated K⁺ conductors, verified by whole-cell voltage clamp.</p>
    Formula:C20H32O2
    Color and Shape:Solid
    Molecular weight:304.47

    Ref: TM-T40650

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    AChE/Aβ-IN-2

    <p>AChE/Aβ-IN-2 (compound 33) is a powerful, orally active acetylcholinesterase (AChE) inhibitor with an IC50 of 135 nM.</p>
    Formula:C20H25ClN4
    Color and Shape:Solid
    Molecular weight:356.89

    Ref: TM-T79571

  • Atagabalin
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    Atagabalin

    CAS:
    <p>Atagabalin (PD 0200390), a gabamimetic for insomnia treatment and related to gabapentin, was halted due to poor trial outcomes.</p>
    Formula:C10H19NO2
    Color and Shape:Solid
    Molecular weight:185.26

    Ref: TM-T30188

  • NT 13
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    NT 13

    CAS:
    <p>NT 13 is a partial N-methyl-D-aspartate receptor (NMDAR) agonist used in the study of depression, anxiety, and other related diseases.</p>
    Formula:C18H30N4O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:414.45

    Ref: TM-TP1023

  • Milbemycin A4
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    Milbemycin A4

    CAS:
    <p>Milbemycin A4, a distinguished member of the macrocyclic lactones family featuring a unique spiroketal group, is derived from the fermentation of the soil bacterium Streptomyces hygroscopicus subsp. aureolacrimosus. It acts by enhancing the opening of glutamate and GABA-gated chloride channels, rendering it effective as both a nematocide and insecticide.</p>
    Formula:C32H46O7
    Color and Shape:Solid
    Molecular weight:542.713

    Ref: TM-TN7268

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    EVT-401

    <p>EVT-401 (P2X7 receptor antagonist-1), a purinergic P2X7 receptor antagonist, demonstrates efficacy in combating neuroinflammation [1].</p>
    Formula:C22H20F4N2O3
    Color and Shape:Solid
    Molecular weight:436.4

    Ref: TM-T74409

  • Cavα2δ-IN-1
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    Cavα2δ-IN-1

    CAS:
    <p>Cavα2δ-IN-1 demonstrates exceptional specificity for voltage-gated calcium channels Cavα2δ-1 (with a Ki value of 6 nM), in comparison to Cavα2δ-2 (with a Ki</p>
    Formula:C18H27N5O
    Color and Shape:Solid
    Molecular weight:329.448

    Ref: TM-T40071

  • 3-Aminopropylphosphinic acid
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    3-Aminopropylphosphinic acid

    CAS:
    <p>3-Aminopropylphosphinic acid (3-APPA) is a phosphonic analog of gamma-aminobutyric acid (GABA).</p>
    Formula:C3H10NO2P
    Color and Shape:Solid
    Molecular weight:123.092

    Ref: TM-T38438

  • Elgodipine
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    Elgodipine

    CAS:
    <p>Elgodipine decreases angina severity, inhibits muscle growth, and is voltage-sensitive, showing promise for angina treatment.</p>
    Formula:C29H33FN2O6
    Purity:98.95% - 99.50%
    Color and Shape:Solid
    Molecular weight:524.58

    Ref: TM-T68060

  • TRPA1 Antagonist 3
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    TRPA1 Antagonist 3

    CAS:
    <p>TRPA1 Antagonist 3 is a compound with photoswitchable properties that acts as an agonist on the TRPA1 channel, providing the ability for optical control.</p>
    Formula:C11H8ClN3
    Color and Shape:Solid
    Molecular weight:217.66

    Ref: TM-T40822

  • CHET3
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    CHET3

    CAS:
    <p>CHET3 is a highly selective allosteric activator for TASK-3-containing K2P channels. CHET3 has shown potent in vivo analgesic effects. Cost-effective and quality-assured.</p>
    Formula:C21H21N5O3S
    Purity:99.64% - >99.99%
    Color and Shape:Soild
    Molecular weight:423.49

    Ref: TM-T72066

  • GsMTx4
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    GsMTx4

    CAS:
    <p>GsMTx-4, mechanosensitive and stretch-activated ion channel inhibitor (CAS 1209500-46-8).</p>
    Formula:C185H273N49O45S6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:4095.84

    Ref: TM-TP1670

  • TRPV4 antagonist 4
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    TRPV4 antagonist 4

    CAS:
    <p>Potent TRPV4 blocker with 22.65 nM IC50; inhibits current and aids acute lung injury.</p>
    Formula:C28H32Cl2N6O
    Color and Shape:Solid
    Molecular weight:539.50

    Ref: TM-T74832

  • WAY-326766
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    WAY-326766

    CAS:
    <p>WAY-326766 increases ion transport through mutant CFTR and can be used to alter the lifespan of eukaryotes.WAY-326766 can be used to treat cystic fibrosis (CF).</p>
    Formula:C21H23N3O5
    Purity:98.76%
    Color and Shape:Solid
    Molecular weight:397.42

    Ref: TM-T77604

  • RuBi-GABA
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    RuBi-GABA

    CAS:
    <p>Ruthenium-bipyridine-triphenylphosphine caged GABA</p>
    Formula:C42H39F6N5O2P2Ru
    Purity:98%
    Color and Shape:Solid
    Molecular weight:922.8

    Ref: TM-T23277

  • Neurotransmitter Receptor Compound Library
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    Neurotransmitter Receptor Compound Library

    <p>A unique collection of 1513 neurotransmitter receptor compounds, can be used for HTS and HCS screening；</p>
    Color and Shape:Odour Solid

    Ref: TM-L2610

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    GpTx-1 TFA

    <p>GpTx-1 TFA is a polypeptide NaV1.7 sodium channel antagonist isolated from the venom of the Chilean spider Grammostola porter. It exhibits potent inhibitory activity on the NaV1.7 channel with an IC50 value of 10 nM, demonstrating excellent selectivity over NaV1.4 (IC50 = 0.301 μM) and NaV1.5 (IC50 = 4.20 μM) with &gt;20-fold and &gt;950-fold selectivity, respectively.</p>
    Color and Shape:Odour Solid

    Ref: TM-TP3232

  • BeKm-1
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    BeKm-1

    CAS:
    <p>Potent, selective hERG (KV11.1) blocker; doesn't affect 14 other K+ channels; extends QTc in rabbit heart dose-dependently.</p>
    Formula:C174H261N51O52S6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:4091.65

    Ref: TM-TP2072

  • 17α-Hydroxywithanolide D
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    17α-Hydroxywithanolide D

    <p>17alpha-Hydroxywithanolide D is an allosteric modulator of the NMDA receptor, with an IC50 of 44.24 nM. This compound exhibits neuroprotective properties and can be utilized in Alzheimer's disease research.</p>
    Formula:C28H46O7
    Color and Shape:Solid
    Molecular weight:494.661

    Ref: TM-T204406

  • Conantokin G
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    Conantokin G

    CAS:
    <p>GluN2B-specific NMDA receptor blocker; IC50=480 nM in neurons, ~300 nM in oocytes; neuroprotective.</p>
    Formula:C88H138N26O44
    Purity:98%
    Color and Shape:White Lyophilised Solid
    Molecular weight:2264.21

    Ref: TM-TP2060

  • (+)-Lycoctonine
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    (+)-Lycoctonine

    CAS:
    <p>Compound TJS1874 is a useful organic compound for research related to life sciences. The catalog number is TJS1874 and the CAS number is 26000-17-9.</p>
    Formula:C25H41NO7
    Color and Shape:Solid
    Molecular weight:467.6

    Ref: TM-TJS1874

  • NF279
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    NF279

    CAS:
    <p>P2X1 antagonist</p>
    Formula:C49H36N6Na6O23S6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1407.17

    Ref: TM-TP2274

  • Ion Channel Targeted Library
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    Ion Channel Targeted Library

    <p>A unique collection of 931 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery;</p>
    Color and Shape:Odour Solid

    Ref: TM-L2300

  • (1S,3R)-3-Aminocyclopentane carboxylic acid
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    (1S,3R)-3-Aminocyclopentane carboxylic acid

    CAS:
    <p>(1S,3R)-3-Aminocyclopentane carboxylic acid exhibits activity on GABAA receptors.</p>
    Formula:C6H11NO2
    Color and Shape:Solid
    Molecular weight:129.16

    Ref: TM-T203289

  • TP-050
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    TP-050

    CAS:
    <p>TP-050: potent, selective NMDAR agonist, EC50 0.51 µM (GluN2A), 9.6 µM (GluN2D), BBB permeable, boosts hippocampal LTP.</p>
    Formula:C16H15ClF2N6O
    Color and Shape:Solid
    Molecular weight:380.78

    Ref: TM-T73491

  • Linoleic Acid Amide
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    Linoleic Acid Amide

    CAS:
    <p>Linoleic Acid Amide (Linoleamide) is derived from linoleic acid and regulates Ca2+ flux by inhibiting the sarco/endoplasmic reticulum Ca2+-ATPase.</p>
    Formula:C18H33NO
    Purity:98%
    Color and Shape:Solid
    Molecular weight:279.46

    Ref: TM-T36812

  • (±)8(9)-EpETE
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    (±)8(9)-EpETE

    CAS:
    <p>(±)8(9)-EpETE ((±)8,9-EEQ) is an epoxide of arachidonic acid biosynthesized by CYP450 epoxygenase.1.2 In rat and rabbit liver microsomes.</p>
    Formula:C20H30O3
    Color and Shape:Solid
    Molecular weight:318.45

    Ref: TM-T37228

  • NF864
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    NF864

    CAS:
    NF864, a suramin analog, is a P2X1 receptor inhibitor.
    Formula:C57H28N6Na12O41S12
    Purity:98%
    Color and Shape:Solid
    Molecular weight:2113.5

    Ref: TM-T25863

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    Jingzhaotoxin-XII TFA

    <p>Jingzhaotoxin-XII (JzTx-XII) TFA is a specific inhibitor of the Kv4.1 channel, exhibiting an IC50 of 0.363 μM. It interacts with the channel by altering gating behavior.</p>
    Color and Shape:Odour Solid

    Ref: TM-TP2888

  • Tiludronate disodium hemihydrate
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    Tiludronate disodium hemihydrate

    CAS:
    <p>Tiludronate: an oral bisphosphonate for bone disorder research; inhibits osteoclasts and reduces inflammation.</p>
    Formula:C14H16Cl2Na4O13P4S2
    Color and Shape:Solid
    Molecular weight:743.16

    Ref: TM-T39037

  • Nitrazolam
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    Nitrazolam

    CAS:
    <p>Nitrazolam is a benzodiazepine compound that may exhibit central nervous system depressant properties similar to traditional benzodiazepine drugs by acting on the GABA receptors (GABA receptor). These effects include sedation, hypnosis, anxiolytic, and anticonvulsant activities.</p>
    Formula:C17H13N5O2
    Color and Shape:Solid
    Molecular weight:319.32

    Ref: TM-T203627

  • APETx2
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    APETx2

    CAS:
    <p>ASIC3 inhibitor; IC50: 63 nM (rat), 175 nM (human). Blocks NaV1.8, NaV1.2; analgesic for acid/inflammatory pain.</p>
    Formula:C196H280N54O61S6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:4561.06

    Ref: TM-TP2081

  • (±)5(6)-DiHETE
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    (±)5(6)-DiHETE

    CAS:
    <p>Eicosapentaenoic acid is an ω-3 polyunsaturated fatty acid that is abundant in marine organisms and fish oils.</p>
    Formula:C20H32O4
    Color and Shape:Solid
    Molecular weight:336.472

    Ref: TM-T37242