Membrane Transporter/Ion Channel
Membrane transporter and ion channel inhibitors are compounds that block the function of proteins responsible for the transport of ions, nutrients, and other molecules across cell membranes. These inhibitors are crucial for studying the regulation of cellular homeostasis, signal transduction, and neurotransmission. Membrane transporter and ion channel inhibitors are also important in developing treatments for disorders such as epilepsy, cardiovascular diseases, and metabolic syndromes. At CymitQuimica, we provide a diverse selection of high-quality membrane transporter and ion channel inhibitors to support your research in physiology, neuroscience, and pharmacology.
Subcategories of "Membrane Transporter/Ion Channel"
- ABC(3 products)
- ATPase(92 products)
- Adiponectin receptor(5 products)
- CFTR(66 products)
- CGRP Receptor(55 products)
- Calcium Channel(578 products)
- Chloride channel(53 products)
- GABA Receptor(367 products)
- Monoamine Transporter(30 products)
- Monocarboxylate transporter(18 products)
- NKCC(2 products)
- NPC1L1(1 products)
- Na-K-Cl cotransporter(9 products)
- OAT(31 products)
- OCT(7 products)
- P-gp(56 products)
- Potassium Channel(318 products)
- Proton pump(42 products)
- SGLT(32 products)
- Sodium Channel(273 products)
- TRP/TRPV Channel(97 products)
Show 13 more subcategories
Found 2690 products for "Membrane Transporter/Ion Channel".
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Roquefortine C
CAS:Roquefortine C is a fungal cyclopeptide isolated from Penicillium roquefortii, activates P-gp and also inhibits P450-3A and other haemoproteinsFormula:C22H23N5O2Purity:98%Color and Shape:SolidMolecular weight:389.453-Aminopropylphosphonic Acid
CAS:3-aminopropylphosphonic acid (3-APPA) is a phosphonic analog of GABA that acts as a partial agonist of GABAB receptors (IC50 = 1.5 μM in a radioligand bindingFormula:C3H10NO3PPurity:99.84%Color and Shape:SolidMolecular weight:139.09Phlotoxin-1 TFA
Phlotoxin-1 (PhlTx1) is a 34-amino acid polypeptide with three disulfide bonds. It is derived from spiders of the Phlogiellus genus. Phlotoxin-1 acts as an antinociceptive agent by inhibiting the NaV1.7 channel.Color and Shape:Odour Solid3-Methoxyeticyclidine hydrochloride
3-Methoxyeticyclidine hydrochloride is a phencyclidine analog with affinity for N-methyl-D-aspartate (NMDA) receptors. It possesses a certain level of toxicity.NF279
CAS:P2X1 antagonistFormula:C49H36N6Na6O23S6Purity:98%Color and Shape:SolidMolecular weight:1407.17NSC156529
CAS:NSC156529 suppresses AKT1, reduces cancer cell growth in vitro, and inhibits prostate tumors in vivo.Formula:C28H21ClS2Purity:98%Color and Shape:SolidMolecular weight:457.05ProTx II
CAS:Selective NaV1.7 inhibitor, alters activation, reduces current, 100x more selective for 1.7 over other Na+ channels.Formula:C168H250N46O41S8Purity:98%Color and Shape:SolidMolecular weight:3826.59Margatoxin
CAS:KV1.3 channel blocker, IC50 36 pM, no effect on calcium-activated channels, hinders VEGF-induced Ca++ influx & NO in endothelial cells.Formula:C178H286N52O50S7Purity:98%Color and Shape:SolidMolecular weight:4178.96JTS-653
CAS:JTS-653 is a potent TRPV1 antagonist, effective in reducing chronic pain unresponsive to NSAIDs.Formula:C23H21F3N4O4Color and Shape:SolidMolecular weight:474.44PDZ1 Domain inhibitor peptide
CAS:Novel cyclic peptide that disrupts interaction between GluR6 and PSD-95Formula:C38H61N9O11Purity:98%Color and Shape:SolidMolecular weight:819.94Dalazatide HCl
Dalazatide HCl is a peptide and specific Kv1.3 inhibitor that suppresses the activation and proliferation of memory effector T cells,Color and Shape:SolidMolecular weight:4317.53 (Free base)Tacrine hydrochloride
CAS:Tacrine: a cholinergic agonist, anticholinesterase; inhibits AChE/BChE with IC50s of 31/25.6 nM.Formula:C13H15ClN2Purity:98%Color and Shape:SolidMolecular weight:234.73Fipronil sulfone
CAS:Fipronil sulfone is an insecticide fipronil. Its metabolite fipronil sulphone is an inhibitor of rat ɑ1β2γ2L GABA(A) receptor.Formula:C12H4Cl2F6N4O2SPurity:98%Color and Shape:SolidMolecular weight:453.14P2X4 antagonist-4
P2X4 antagonist-4 (compound 64) is a potent P2X4R antagonist with an IC50 value of 8 µM. It can inhibit ATP-induced activation of the NLRP3 inflammasome and the subsequent release of IL-1β.Formula:C27H22FN3O4SColor and Shape:SolidMolecular weight:503.545Bendroflumethiazide
CAS:Bendroflumethiazide (Naturetin) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p810)Formula:C15H14F3N3O4S2Purity:98% - >99.99%Color and Shape:White SolidMolecular weight:421.41GYKI-47261 dihydrochloride
CAS:GYKI-47261 dihydrochloride is an AMPA receptor antagonist and CYP2E1 inducer, demonstrating broad-spectrum anticonvulsant and neuroprotective activities.Formula:C18H17Cl3N4Purity:98.32% - 99.14%Color and Shape:White SolidMolecular weight:395.71epi-Aszonalenin A
CAS:epi-Aszonalenin A: a psychoactive benzodiazepine from Aspergillus novofumigatus.Formula:C25H25N3O3Color and Shape:SolidMolecular weight:415.48Kv3.1 modulator 2
Kv3.1 modulator 2 is an agent that regulates Kv3.1 channels, exhibiting an EC50 value of 68 nM.Formula:C22H20ClN5O3Color and Shape:SolidMolecular weight:437.12547Nipecotic acid
CAS:Nipecotic acid ,with CAS No. 498-95-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Nipecotic acid provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C6H11NO2Color and Shape:Off-White To Pale Yellow-Beige PowderMolecular weight:129.16P-gp inhibitor 15
P-gp Inhibitor 15 (compound 7a), a nonsubstrate inhibitor of P-glycoprotein (Pgp), inhibits Pgp-ATPase activity and interferes with Pgp-mediated Rhodamine123Formula:C35H60N2O4Color and Shape:SolidMolecular weight:572.86(-)-(S)-Cibenzoline
CAS:Cibenzoline, also known as Escibenzoline, is the S(+)-enantiomer of Cibenzoline and functions as an antiarrhythmic agent.Formula:C18H18N2Color and Shape:SolidMolecular weight:262.35Oleoyl-D-lysine
CAS:Oleoyl-D-lysine: lipid-based GlyT2 inhibitor, eases neuropathic pain in mice, safe, non-sedative, no respiratory depression.Formula:C24H46N2O3Color and Shape:SolidMolecular weight:410.63JYL-79
CAS:JYL-79 is an agonist of the vanilloid receptor.Formula:C26H36N2O4SColor and Shape:SolidMolecular weight:472.64MRS4596
MRS4596: selective P2X4 blocker, IC50 1.38 μM, neuroprotective in stroke research.Formula:C21H14N5NaO3SColor and Shape:SolidMolecular weight:439.42MS7710
MS7710 is a brain-penetrant inhibitor of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels. It reduces Ih current by inhibiting HCN channels, thereby decreasing the activity of dopamine neurons in the ventral tegmental area (VTA). MS7710 effectively improves social interaction deficits and reward-related cognitive flexibility in mouse models of chronic social defeat stress (CSDS) and shows promise for depression research.Color and Shape:Odour Solid17α-Hydroxywithanolide D
17alpha-Hydroxywithanolide D is an allosteric modulator of the NMDA receptor, with an IC50 of 44.24 nM. This compound exhibits neuroprotective properties and can be utilized in Alzheimer's disease research.Formula:C28H46O7Color and Shape:SolidMolecular weight:494.661Conantokin G
CAS:GluN2B-specific NMDA receptor blocker; IC50=480 nM in neurons, ~300 nM in oocytes; neuroprotective.Formula:C88H138N26O44Purity:98%Color and Shape:SolidMolecular weight:2264.21TRPA1-IN-1
CAS:TRPA1-IN-1 is a potent, selective antagonist of the TRPA1 channel, demonstrating significant oral bioavailability as a small molecule.Formula:C19H17ClN6O3Color and Shape:SolidMolecular weight:412.83(+)-Lycoctonine
CAS:Compound TJS1874 is a useful organic compound for research related to life sciences. The catalog number is TJS1874 and the CAS number is 26000-17-9.Formula:C25H41NO7Color and Shape:SolidMolecular weight:467.6LU-32-176B
CAS:LU32-176B is a bioactive chemical.Formula:C23H24F2N2O2Color and Shape:SolidMolecular weight:398.45GeX-2
CAS:GeX-2 is a truncated analogue of αO-conotoxin. It has the ability to activate GABAB receptors and inhibit α9α10nAChR as well as CaV2.2 channels. Additionally, GeX-2 is effective in alleviating pain in a rat model of chronic constriction injury.Formula:C103H169N43O27Color and Shape:SolidMolecular weight:2441.72Tiludronate disodium hemihydrate
CAS:Tiludronate: an oral bisphosphonate for bone disorder research; inhibits osteoclasts and reduces inflammation.Formula:C14H16Cl2Na4O13P4S2Color and Shape:SolidMolecular weight:743.16(S)-PF-03716556
CAS:(S)-PF-03716556 can be used as an acid pump inhibitor for the treatment of disease conditions mediated by acid pump inhibitory activity.Formula:C22H26N4O3Purity:99.75% - 99.91%Color and Shape:White SolidMolecular weight:394.47Apamin acetate
Apamin acetate: Selective Ca2+-activated K+ channel blocker, 18-amino acid bee venom peptide, promotes synapse repair, anti-inflammatory.Purity:99.42%Color and Shape:SolidNav1.7-IN-8
CAS:Nav1.7-IN-8 selectively inhibits NaV1.7 over hNaV1.1/1.5, affects CYP2C9/3A4 (IC50: 0.17/0.077 μM), and provides rodent pain relief.Formula:C21H12ClF2N5O4S2Color and Shape:SolidMolecular weight:535.93SNX-482
CAS:Potent CaV2.3 calcium channel blocker, selective, voltage-dependent, with 30 nM IC50. Offers antinociceptive effects on C and Aδ fibres.Formula:C192H274N52O60S7Purity:98%Color and Shape:SolidMolecular weight:4495.01Linoleic Acid Amide
CAS:Linoleic Acid Amide (Linoleamide) is derived from linoleic acid and regulates Ca2+ flux by inhibiting the sarco/endoplasmic reticulum Ca2+-ATPase.Formula:C18H33NOPurity:98.41%Color and Shape:Yellow SolidMolecular weight:279.46ω-Conotoxin MVIIC
CAS:Peptide neurotoxin; wide spectrum blocker of N, P and Q type calcium channels.Formula:C106H178N40O32S7Purity:98%Color and Shape:SolidMolecular weight:2749Resolvin D2 methyl ester
CAS:RvD2 is an anti-inflammatory lipid made from docosahexaenoic acid by 15- and 5-lipoxygenase. Its methyl ester may serve as a prodrug.Formula:C23H34O5Color and Shape:SolidMolecular weight:390.52α,β-Methylene-ATP dilithium
CAS:α,β-Methylene ATP dilithium, a phosphonic analog of ATP, serves as a ligand for P2X3 and P2X7 receptors.Formula:C11H16Li2N5O12P3Color and Shape:SolidMolecular weight:517.07MIDD0301
CAS:MIDD0301 is a potent positive allosteric α5β3γ selective GABAA receptor (GABAAR) ligand with EC50 of 17 nM.Formula:C19H13BrFN3O2Purity:98%Color and Shape:SolidMolecular weight:414.23Phe-Met-Arg-Phe, amide
CAS:Phe-Met-Arg-Phe amide activates K+ current in neurons (ED50=23 nM), co-localizes with neuropeptide Y in brain regions.Formula:C29H42N8O4SPurity:98%Color and Shape:SolidMolecular weight:598.76(±)17-HETE
CAS:Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites.Formula:C20H32O3Color and Shape:SolidMolecular weight:320.473Agitoxin-2
CAS:Potent Shaker K+ channel blocker (Ki = 0.64 nM). Also inhibits Kv1.3, Kv1.6 and Kv1.1 K+ channels (Ki values are 4, 37 and 44 pM respectively).Formula:C169H278N54O48S8Purity:98%Color and Shape:SolidMolecular weight:4090.87LY-466195
CAS:LY-466195 is a competitive antagonist of GLUK5 receptor.Formula:C16H24F2N2O4Color and Shape:SolidMolecular weight:346.37Chrodrimanin B
CAS:Chrodrimanin B is a useful organic compound for research related to life sciences. The catalog number is T126052 and the CAS number is 132196-54-4.Formula:C27H32O8Color and Shape:SolidMolecular weight:484.545Transdermal Peptide Disulfide
CAS:TD 1 peptide, an 11-amino acid, binds ATP1B1's C-terminus, enhancing transdermal drug delivery.Formula:C40H64N14O16S2Purity:98%Color and Shape:SolidMolecular weight:1061.15GluN2B-NMDAR antagonist-1
Orally active GluN2B-NMDAR antagonist with neuroprotective properties for ischemic injury research.Formula:C26H23BrN2O2Color and Shape:SolidMolecular weight:475.38Huwentoxin-IV
CAS:Selective NaV1.7 blocker; also inhibits NaV1.2, 1.3; less effect on NaV1.4, 1.5. Binds to neurotoxin site, traps voltage sensor. IC50: 26-338 nM.Formula:C174H278N52O51S6Purity:98%Color and Shape:SolidMolecular weight:4106.79P-gp inhibitor 13
P-gp Inhibitor 13, a P-glycoprotein antagonist, can counteract paclitaxel resistance in A2780/T cells, proving valuable for advanced acute myeloid leukemiaFormula:C32H34O8Color and Shape:SolidMolecular weight:546.61
