Membrane Transporter/Ion Channel
Membrane transporter and ion channel inhibitors are compounds that block the function of proteins responsible for the transport of ions, nutrients, and other molecules across cell membranes. These inhibitors are crucial for studying the regulation of cellular homeostasis, signal transduction, and neurotransmission. Membrane transporter and ion channel inhibitors are also important in developing treatments for disorders such as epilepsy, cardiovascular diseases, and metabolic syndromes. At CymitQuimica, we provide a diverse selection of high-quality membrane transporter and ion channel inhibitors to support your research in physiology, neuroscience, and pharmacology.
Subcategories of "Membrane Transporter/Ion Channel"
- ABC(3 products)
- ATPase(99 products)
- Adiponectin receptor(5 products)
- CFTR(66 products)
- CGRP Receptor(53 products)
- Calcium Channel(547 products)
- Chloride channel(54 products)
- GABA Receptor(369 products)
- Monoamine Transporter(30 products)
- Monocarboxylate transporter(18 products)
- NKCC(2 products)
- NPC1L1(3 products)
- Na-K-Cl cotransporter(10 products)
- OAT(32 products)
- OCT(7 products)
- P-gp(55 products)
- Potassium Channel(289 products)
- Proton pump(41 products)
- SGLT(31 products)
- Sodium Channel(223 products)
- TRP/TRPV Channel(96 products)
Show 13 more subcategories
Found 2645 products of "Membrane Transporter/Ion Channel"
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O4I4
CAS:O4I4 is an OCT4-inducing compound capable of activating endogenous OCT4 and its associated signaling pathways, shown anti-aging effects.Formula:C15H20N2SPurity:99.74%Color and Shape:SolidMolecular weight:260.4SGC-CAMKK2-1
CAS:SGC-CAMKK2-1 is a selective inhibitor of calcium/calmodulin-dependent protein kinase kinase 2 (CAMKK2) with an IC50 of 30 nM. It effectively inhibits AMPK phosphorylation in C4-2 cells, exhibiting an IC50 value of 1.6 µM.Formula:C26H23NO3Color and Shape:SolidMolecular weight:397.466Antidepressant agent 8
CAS:Antidepressant agent 8 (Compound 1f) acts as a selective antagonist for the NMDA receptor GluN1/2A (NMDA receptorGluN1/2A), with an IC50 of 2.94 μmol/L. In a hydrocortisone-induced zebrafish depression model, it demonstrates antidepressant-like effects and shows good blood-brain barrier penetration.Formula:C18H23FN4OS2Color and Shape:SolidMolecular weight:394.53LY503430
CAS:LY503430: Oral AMPA enhancer with nootropic, neuroprotective properties, mitigates 6-OHDA/MPTP brain damage.Formula:C20H25FN2O3SPurity:98%Color and Shape:SolidMolecular weight:392.49Antimalarial agent 7
Antimalarial agent 7 is a potent and effective inhibitor of PfATP4. Antimalarial agent 7 has potential for the study of the human plasmodium falciparum.Formula:C23H22F2N4O3Color and Shape:SolidMolecular weight:440.44Olisutrigine bromide
CAS:Olisutrigine bromide is a sodium channel blocker used as an analgesic.Formula:C25H35BrN2Color and Shape:SolidMolecular weight:443.463ErSO-TFPy
CAS:ErSO-TFPy activates the sodium ion channel TRPM4, resulting in an imbalance of intracellular calcium and sodium ions. It exhibits low nanomolar-level cytotoxicity (IC50 = 5-25 nM) by inducing necrosis in ERα+ breast cancer cell lines. Additionally, ErSO-TFPy shows antitumor activity in mouse models.Formula:C19H13F7N2O2Color and Shape:SolidMolecular weight:434.307Moxetomidate
CAS:Moxetomidate is a GABAA receptor (GABAA receptor) agonist with hypnotic properties.Formula:C15H18N2O3Color and Shape:SolidMolecular weight:274.315Crinecerfont tosylate
CAS:Crinecerfont tosylate is an effective oral CRF1 receptor antagonist. It is applicable to studies involving congenital adrenal hyperplasia (CAH).Formula:C34H36ClFN2O4S2Color and Shape:SolidMolecular weight:655.242(3S,6R)-NML
CAS:(3S,6R)-NML is an NMDA receptor antagonist with pIC50 values of 4.8 [GluN1-GluN2A], 4.6 [GluN1-GluN2B], 5.0 [GluN1-GluN2C], and 5.0 [GluN1-GluN2D]. It is applicable in the study of depression.Formula:C20H27NOColor and Shape:SolidMolecular weight:297.435URAT1 inhibitor 2
URAT1 inhibitor 2: oral URAT1/CYP blocker, IC50 of 1.36μM (URAT1), 16.97μM (CYP1A2), 5.22μM (CYP2C9); potential gout treatment.Formula:C21H18BrN3O2SColor and Shape:SolidMolecular weight:456.36Insecticidal agent 21
CAS:Insecticidal agent 21 (Compound 6) is an insecticide targeting Culex pipiens larvae with an LC50 of 0.4 μg/mL. It achieves multi-target neurotoxicity by inhibiting acetylcholinesterase (AChE) and simultaneously targeting other neural receptors, including nicotinic acetylcholine receptors (nAChR), voltage-gated sodium channels (VGSC), and γ-aminobutyric acid receptors (GABAAR). Insecticidal agent 21 shows potent insecticidal activity and can be utilized in the development of new insecticides to combat mosquito resistance to conventional agents.Formula:C37H40ClN3O2Color and Shape:SolidMolecular weight:594.185ATPase-IN-5
CAS:ATPase-IN-5 (Compound 11) is an antifungal Pma1p (H+ -ATPase) inhibitor (IC50 = 12.7 μM) that inhibits the growth of Candida albicans and Saccharomyces cerevisiae.
Formula:C10H10N4O3SPurity:99.19%Color and Shape:SolidMolecular weight:266.28Ref: TM-T204943
1mg185.00€5mg459.00€10mg657.00€25mg1,026.00€50mg1,415.00€100mg1,872.00€200mg2,555.00€PDE1-IN-4
PDE1-IN-4: inhibits PDE1C/A/B with IC50s 10/145/354 nM, may help study idiopathic pulmonary fibrosis.Formula:C33H33N3O4Color and Shape:SolidMolecular weight:535.63P2X receptor-1
P2X receptor-1 is a potential inhibitor of P2X receptor for the treatment of pain and inflammation.Formula:C14H14ClN3O3S2Color and Shape:SolidMolecular weight:371.865-O-Desmethyl donepezil
CAS:5-O-Desmethyl donepezil is a metabolite of Donepezil that acts as an inhibitor of hERG channels, with an IC50 of 1.5 μM.Formula:C23H27NO3Color and Shape:SolidMolecular weight:365.465ICA-105665
CAS:ICA-105665 is an orally active Kv7.2/7.3/7.5 channel opener, CNS-penetrant with antiseizure effects, and low hepatocyte cytotoxicity.Formula:C19H15F2N3O2Purity:98%Color and Shape:SolidMolecular weight:355.34GNE-616
CAS:GNE-616: a potent, stable, oral Nav1.7 inhibitor; Ki: 0.79 nM, Kd: 0.38 nM; for chronic pain.Formula:C24H23F4N5O3SPurity:98%Color and Shape:SolidMolecular weight:537.53(RS)-AMPA hydrobromide
CAS:AMPAR agonistFormula:C7H11BrN2O4Purity:98%Color and Shape:SolidMolecular weight:267.08KV1.3-IN-2
CAS:KV1.3-IN-2 (Compound I) selectively inhibits the kv1.3 potassium channel without affecting the hERG channel. It is applicable in research related to immune-associated diseases such as psoriasis, rheumatoid arthritis, and systemic lupus erythematosus.Formula:C16H23ClN2O4Color and Shape:SolidMolecular weight:342.818
