Membrane Transporter/Ion Channel
Membrane transporter and ion channel inhibitors are compounds that block the function of proteins responsible for the transport of ions, nutrients, and other molecules across cell membranes. These inhibitors are crucial for studying the regulation of cellular homeostasis, signal transduction, and neurotransmission. Membrane transporter and ion channel inhibitors are also important in developing treatments for disorders such as epilepsy, cardiovascular diseases, and metabolic syndromes. At CymitQuimica, we provide a diverse selection of high-quality membrane transporter and ion channel inhibitors to support your research in physiology, neuroscience, and pharmacology.
Subcategories of "Membrane Transporter/Ion Channel"
- ABC(3 products)
- ATPase(97 products)
- Adiponectin receptor(5 products)
- CFTR(66 products)
- CGRP Receptor(52 products)
- Calcium Channel(563 products)
- Chloride channel(54 products)
- GABA Receptor(370 products)
- Monoamine Transporter(30 products)
- Monocarboxylate transporter(18 products)
- NKCC(2 products)
- NPC1L1(3 products)
- Na-K-Cl cotransporter(10 products)
- OAT(32 products)
- OCT(7 products)
- P-gp(55 products)
- Potassium Channel(294 products)
- Proton pump(42 products)
- SGLT(31 products)
- Sodium Channel(241 products)
- TRP/TRPV Channel(96 products)
Show 13 more subcategories
Found 2685 products of "Membrane Transporter/Ion Channel"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
GaTx2
CAS:High-affinity ClC-2 blocker (KD ~50 pM), selective over other ClCs/CFTR/GABAC/CaCC/KV1.2; slows activation, no effect on open channels.Formula:C125H199N39O47S6Purity:98%Color and Shape:SolidMolecular weight:3192.54LTGO-33
CAS:LTGO-33 is a voltage-gated sodium channel NaV1.8 inhibitor that inhibits NaV1.8, NaV1.1-NaV1.7, and NaV1.9.
Formula:C21H17F4N3O3SPurity:97.6%Color and Shape:SoildMolecular weight:467.44Fipronil sulfone
CAS:Fipronil sulfone is an insecticide fipronil. Its metabolite fipronil sulphone is an inhibitor of rat ɑ1β2γ2L GABA(A) receptor.Formula:C12H4Cl2F6N4O2SPurity:98%Color and Shape:SolidMolecular weight:453.14Chrodrimanin B
CAS:Chrodrimanin B is a useful organic compound for research related to life sciences. The catalog number is T126052 and the CAS number is 132196-54-4.Formula:C27H32O8Color and Shape:SolidMolecular weight:484.545ABCB1-IN-1
ABCB1-IN-1 (compound 3) is a potent inhibitor of ABCB1 that promotes cell apoptosis.Formula:C36H33F3FeN2O4PSColor and Shape:SolidMolecular weight:733.54JTS-653
CAS:JTS-653 is a potent TRPV1 antagonist, effective in reducing chronic pain unresponsive to NSAIDs.Formula:C23H21F3N4O4Color and Shape:SolidMolecular weight:474.44ω-Agatoxin IVA
CAS:Selective blocker of P-type calcium channels (IC50 < 1 - 3 nM). Also inhibits N-type channels at micromolar concentrations.Formula:C217H360N68O60S10Purity:98%Color and Shape:SolidMolecular weight:5202.25α5-GABAA receptor modulator 1
α5-GABAA receptor modulator 1 (Compound A-4) is a selective silent allosteric modulator (SAM) targeting the α5 subunit of GABAA receptors, useful for research into central nervous system (CNS) disorders.Formula:C21H20FN3O4Color and Shape:SolidMolecular weight:397.4S-Sulfo-L-cysteine sodium salt
CAS:S-Sulfo-L-cysteine sodium salt shows a weak affinity for mGluR1α and mGluR5a at high concentrations and has potential antioxidant activity.Formula:C3H6NNaO5S2Purity:99.59%Color and Shape:SolidMolecular weight:223.2Margatoxin
CAS:KV1.3 channel blocker, IC50 36 pM, no effect on calcium-activated channels, hinders VEGF-induced Ca++ influx & NO in endothelial cells.Formula:C178H286N52O50S7Purity:98%Color and Shape:SolidMolecular weight:4178.96Concanamycin B
CAS:Concanamycin B, a macrolide, inhibits V-ATPases (IC50 = 5 nM), blocks vacuole acidification, affects bone resorption, CD8 T cells, and MHC II in B cells.Formula:C45H73NO14Color and Shape:SolidMolecular weight:852.072Ethacrynic acid D5
CAS:Ethacrynic acid: a diuretic, anti-inflammatory, inhibits calcium channels, GSTs, NF-kB pathway, and modulates leukotriene; has deuterium-labeled form.Formula:C13H12Cl2O4Purity:98%Color and Shape:SolidMolecular weight:308.17Huwentoxin-IV
CAS:Selective NaV1.7 blocker; also inhibits NaV1.2, 1.3; less effect on NaV1.4, 1.5. Binds to neurotoxin site, traps voltage sensor. IC50: 26-338 nM.Formula:C174H278N52O51S6Purity:98%Color and Shape:SolidMolecular weight:4106.79Phe-Met-Arg-Phe amide trifluoroacetate
CAS:Phe-met-arg-phe amide trifluoroacetate is an activator of K+ current with an ED50 of 23nm on the fundus nerve.Formula:C33H44F6N8O8SPurity:98%Color and Shape:SolidMolecular weight:826.81GluN2B-NMDAR antagonist-1
Orally active GluN2B-NMDAR antagonist with neuroprotective properties for ischemic injury research.Formula:C26H23BrN2O2Color and Shape:SolidMolecular weight:475.38Dalazatide HCl
Dalazatide HCl is a peptide and specific Kv1.3 inhibitor that suppresses the activation and proliferation of memory effector T cells,Color and Shape:SolidMolecular weight:4317.53 (Free base)Iberiotoxin
CAS:Selective blocker of the big conductance Ca2+-activated K+ channel.Formula:C179H274N50O55S7Purity:98%Color and Shape:SolidMolecular weight:4230P2X4 antagonist-4
P2X4 antagonist-4 (compound 64) is a potent P2X4R antagonist with an IC50 value of 8 µM. It can inhibit ATP-induced activation of the NLRP3 inflammasome and the subsequent release of IL-1β.Formula:C27H22FN3O4SColor and Shape:SolidMolecular weight:503.545MIDD0301
CAS:MIDD0301 is a potent positive allosteric α5β3γ selective GABAA receptor (GABAAR) ligand with EC50 of 17 nM.
Formula:C19H13BrFN3O2Purity:98%Color and Shape:SolidMolecular weight:414.23Tacrine hydrochloride
CAS:Tacrine: a cholinergic agonist, anticholinesterase; inhibits AChE/BChE with IC50s of 31/25.6 nM.Formula:C13H15ClN2Purity:98%Color and Shape:SolidMolecular weight:234.73
