Membrane Transporter/Ion Channel
Membrane transporter and ion channel inhibitors are compounds that block the function of proteins responsible for the transport of ions, nutrients, and other molecules across cell membranes. These inhibitors are crucial for studying the regulation of cellular homeostasis, signal transduction, and neurotransmission. Membrane transporter and ion channel inhibitors are also important in developing treatments for disorders such as epilepsy, cardiovascular diseases, and metabolic syndromes. At CymitQuimica, we provide a diverse selection of high-quality membrane transporter and ion channel inhibitors to support your research in physiology, neuroscience, and pharmacology.
Subcategories of "Membrane Transporter/Ion Channel"
- ABC(3 products)
- ATPase(98 products)
- Adiponectin receptor(5 products)
- CFTR(66 products)
- CGRP Receptor(52 products)
- Calcium Channel(562 products)
- Chloride channel(54 products)
- GABA Receptor(370 products)
- Monoamine Transporter(30 products)
- Monocarboxylate transporter(18 products)
- NKCC(2 products)
- NPC1L1(3 products)
- Na-K-Cl cotransporter(10 products)
- OAT(32 products)
- OCT(7 products)
- P-gp(55 products)
- Potassium Channel(295 products)
- Proton pump(42 products)
- SGLT(31 products)
- Sodium Channel(241 products)
- TRP/TRPV Channel(96 products)
Show 13 more subcategories
Found 2676 products of "Membrane Transporter/Ion Channel"
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Apamin
CAS:Apamin: 18-amino acid bee venom peptide, blocks SK channels, anti-inflammatory, anti-fibrotic, strongly basic.Formula:C79H131N31O24S4Purity:98%Color and Shape:SolidMolecular weight:2027.34Brevetoxin-3
CAS:Brevetoxin-3 activates Na+ channels, binding strongly to site 5, preventing their inactivation.Formula:C50H72O14Purity:98%Color and Shape:SolidMolecular weight:897.112α-Casozepine
CAS:α-Casozepine,Bioactive peptide from milk α-S1 casein. Binds GABA receptors. Anti-anxiety effects.Formula:C60H94N14O16Color and Shape:SolidMolecular weight:1267.47L-Palmitoylcarnitine TFA
L-Palmitoylcarnitine TFA: long-chain fat metabolite that disrupts membranes in ischaemia & inhibits KATP channels via Kir6.2 interaction.
Formula:C25H46F3NO6Color and Shape:SolidMolecular weight:513.63Crofelemer
CAS:Crofelemer (Provir) is an orally active antidiarrheal agent. It targets the cystic fibrosis transmembrane conductance regulator (CFTR) and calcium-activated chloride channels (CACC), which are responsible for chloride and fluid secretion in the gastrointestinal tract. Crofelemer is applicable for research in diarrhea-related conditions.Color and Shape:Solid17(S)-HETE
CAS:Arachidonic acid and its CYP450 metabolite, 17(S)-HETE, regulate kidney electrolytes; 17(S)-HETE reduces proximal tubule ATPase activity by 70% at 2 μM.
Formula:C20H32O3Color and Shape:SolidMolecular weight:320.4735-Hydroxy-2′,3,4′,7-tetramethoxyflavone
CAS:5-Hydroxy-2′,3,4′,7-tetramethoxyflavone shows weak ABCG2 inhibitory potency with IC50s of 3.27 and 3.89 µM in the Hoechst 33342 and pheophorbide A assays.Formula:C19H18O7Purity:98%Color and Shape:SoildMolecular weight:358.34Analgesic/antidepressant agent-1
Analgesic/antidepressant agent-1 (Compound k1) is an orally active N-acetylamino chloro ketone derivative capable of crossing the blood-brain barrier. It exhibits high affinity for NMDA receptors and demonstrates analgesic, anti-inflammatory, and antidepressant properties, with low psychotomimetic activity.Formula:C22H25ClN2O2Color and Shape:SolidMolecular weight:384.9JAMI1001A
CAS:JAMI1001A enhances AMPA receptor signaling, slows deactivation/desensitization for flip/flop isoforms.Formula:C16H17F3N4O3SColor and Shape:SolidMolecular weight:402.39ProTx II
CAS:Selective NaV1.7 inhibitor, alters activation, reduces current, 100x more selective for 1.7 over other Na+ channels.
Formula:C168H250N46O41S8Purity:98%Color and Shape:SolidMolecular weight:3826.59GSK2332255B
CAS:GSK2332255B: potent TRPC3/6 antagonist; IC50 5 nM (TRPC3), 4 nM (TRPC6); over 100-fold selectivity vs other Ca2+ channels.Formula:C18H19ClFN3O3SColor and Shape:SolidMolecular weight:411.88TP-050
CAS:TP-050: potent, selective NMDAR agonist, EC50 0.51 µM (GluN2A), 9.6 µM (GluN2D), BBB permeable, boosts hippocampal LTP.Formula:C16H15ClF2N6OColor and Shape:SolidMolecular weight:380.78Vedroprevir
CAS:Vedroprevir (GS9451), a selective HCV NS3 protease inhibitor, targets genotype 1 HCV.Formula:C45H60ClN7O9SColor and Shape:SolidMolecular weight:910.53AP14145 hydrochloride
CAS:AP14145 hydrochloride inhibits KCa2.2 and KCa2.3 channels with 1.1 μM IC50, affecting AERP and antiarrhythmic in AF models.Formula:C18H18ClF3N4OColor and Shape:SolidMolecular weight:398.81Phe-Met-Arg-Phe, amide
CAS:Phe-Met-Arg-Phe amide activates K+ current in neurons (ED50=23 nM), co-localizes with neuropeptide Y in brain regions.Formula:C29H42N8O4SPurity:98%Color and Shape:SolidMolecular weight:598.76rac-trans-4-hydroxy Glyburide
CAS:rac-trans-4-hydroxy Glyburide, a metabolite of glyburide, inhibits binding at SUR1/Kir6.2 sites with IC50 values of 0.95 and 100 nM.Formula:C23H28ClN3O6SColor and Shape:SolidMolecular weight:510.0ω-Agatoxin TK
CAS:Selective blocker of CaV2.1 P/Q-type calcium channels.Formula:C215H337N65O70S10Purity:98%Color and Shape:SolidMolecular weight:5273.02P2X4 antagonist-3
P2X4 antagonist-3 (Compound 14c) is a P2X4 inhibitor with an IC50 value of 1.2 μM. It holds potential for research into neuroinflammation, chronic pain, and cancer progression.Formula:C19H20FN3O4Color and Shape:SolidMolecular weight:373.38Anticonvulsant agent 9
Anticonvulsant agent 9 (compound 4f) is an activator of the α1β2γ2GABA_A receptor, with an EC50 value of 1.24 μM. It inhibits the inactivation of Nav1.2 channels and exhibits significant anticonvulsant activity.Formula:C22H24N4O2Color and Shape:SolidMolecular weight:376.45TNP-ATP triethylammonium salt
CAS:P2X receptor antagonistFormula:C40H77N12O19P3Purity:98%Color and Shape:SolidMolecular weight:1123.042
