Membrane Transporter/Ion Channel
Membrane transporter and ion channel inhibitors are compounds that block the function of proteins responsible for the transport of ions, nutrients, and other molecules across cell membranes. These inhibitors are crucial for studying the regulation of cellular homeostasis, signal transduction, and neurotransmission. Membrane transporter and ion channel inhibitors are also important in developing treatments for disorders such as epilepsy, cardiovascular diseases, and metabolic syndromes. At CymitQuimica, we provide a diverse selection of high-quality membrane transporter and ion channel inhibitors to support your research in physiology, neuroscience, and pharmacology.
Subcategories of "Membrane Transporter/Ion Channel"
- ABC(3 products)
- ATPase(99 products)
- Adiponectin receptor(5 products)
- CFTR(66 products)
- CGRP Receptor(53 products)
- Calcium Channel(554 products)
- Chloride channel(54 products)
- GABA Receptor(369 products)
- Monoamine Transporter(30 products)
- Monocarboxylate transporter(18 products)
- NKCC(2 products)
- NPC1L1(3 products)
- Na-K-Cl cotransporter(10 products)
- OAT(32 products)
- OCT(7 products)
- P-gp(55 products)
- Potassium Channel(289 products)
- Proton pump(42 products)
- SGLT(31 products)
- Sodium Channel(230 products)
- TRP/TRPV Channel(96 products)
Show 13 more subcategories
Found 2649 products of "Membrane Transporter/Ion Channel"
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P-gp inhibitor 15
P-gp Inhibitor 15 (compound 7a), a nonsubstrate inhibitor of P-glycoprotein (Pgp), inhibits Pgp-ATPase activity and interferes with Pgp-mediated Rhodamine123Formula:C35H60N2O4Color and Shape:SolidMolecular weight:572.86S-Sulfo-L-cysteine sodium salt
CAS:S-Sulfo-L-cysteine sodium salt shows a weak affinity for mGluR1α and mGluR5a at high concentrations and has potential antioxidant activity.Formula:C3H6NNaO5S2Purity:99.59%Color and Shape:SolidMolecular weight:223.2N-Arachidonoyl Taurine
CAS:N-Arachidonoyl taurine, an amino acid, activates TRPV1/TRPV4, is metabolized by lipoxygenase, and affects insulin secretion and calcium flux.Formula:C22H37NO4SColor and Shape:SolidMolecular weight:411.6TRPA1-IN-2
CAS:TRPA1-IN-2 is a potent and orally active TRPA1 inhibitor with an IC50 value of 0.04 µM.TRPA1-IN-2 has anti-inflammatory activity.Formula:C24H25F3N4OPurity:98.93%Color and Shape:SoildMolecular weight:442.48Ref: TM-T77511
1mg56.00€5mg129.00€10mg188.00€25mg319.00€50mg447.00€100mg600.00€200mg807.00€1mL*10mM (DMSO)142.00€Leptomycin A
CAS:Leptomycin A from Streptomyces inhibits CRM1, reducing HIV-1 replication, less potent than Leptomycin B, blocks protein nuclear export.Formula:C32H46O6Purity:98%Color and Shape:SolidMolecular weight:526.7TRPA1-IN-1
CAS:TRPA1-IN-1 is a potent, selective antagonist of the TRPA1 channel, demonstrating significant oral bioavailability as a small molecule.Formula:C19H17ClN6O3Color and Shape:SolidMolecular weight:412.83Monascorubrin
CAS:Monascorubrin, from Monascus purpureus mycelium, is an antibiotic against Bacillus subtilis and Candida pseudotropicalis.Formula:C23H26O5Color and Shape:SolidMolecular weight:382.45PptT-IN-4
PptT-IN-4 (Compound 3a) is a PptT inhibitor exhibiting an IC50 of 0.71 μM.Formula:C17H23N3Purity:98%Color and Shape:SolidMolecular weight:269.38Lifarizine FA
Lifarizine FA is a sodium channel blocker used in the treatment of neurological disorders and cardiovascular diseases, study of stroke.Formula:C30H34N4O2Purity:99.55%Color and Shape:SolidMolecular weight:482.62AChE/Aβ-IN-1
AChE/Aβ-IN-1 (compound 32) is a potent, orally active acetylcholinesterase (AChE) inhibitor with an IC50 of 86 nM and an NMDA receptor antagonist targeting theFormula:C20H25BrN4Color and Shape:SolidMolecular weight:401.34Atagabalin
CAS:Atagabalin (PD 0200390), a gabamimetic for insomnia treatment and related to gabapentin, was halted due to poor trial outcomes.Formula:C10H19NO2Color and Shape:SolidMolecular weight:185.26SNX-482
CAS:Potent CaV2.3 calcium channel blocker, selective, voltage-dependent, with 30 nM IC50. Offers antinociceptive effects on C and Aδ fibres.Formula:C192H274N52O60S7Purity:98%Color and Shape:SolidMolecular weight:4495.01Apamin acetate
Apamin acetate: Selective Ca2+-activated K+ channel blocker, 18-amino acid bee venom peptide, promotes synapse repair, anti-inflammatory.Purity:96.97%Color and Shape:SolidLaniquidar TFA
Laniquidar TFA (R101933), a non-competitive P-gp inhibitor, has an IC50 of 0.51 μM; used to study AML and MDS, but with limited bioavailability.Formula:C39H37F3N4O5Purity:99.85%Color and Shape:SoildMolecular weight:698.73GluN2B receptor modulator-1
CAS:GluN2B receptor modulator-1 is a selective negative allosteric modulator of NMDA receptor GluN2B subunits (IC50 31 nM), valuable for neuropharmacology studies.Formula:C17H15F3N4O2SPurity:99.56%Color and Shape:SolidMolecular weight:396.39Mambalgin 1
CAS:ASIC1a inhibitor; IC50: 192 nM (human), 72 nM (dimer); inactive channel binding; selective; pain response delay.Formula:C272H429N85O84S10Purity:98%Color and Shape:SolidMolecular weight:6554.51Huwentoxin-IV
CAS:Selective NaV1.7 blocker; also inhibits NaV1.2, 1.3; less effect on NaV1.4, 1.5. Binds to neurotoxin site, traps voltage sensor. IC50: 26-338 nM.Formula:C174H278N52O51S6Purity:98%Color and Shape:SolidMolecular weight:4106.79GDC-0334
CAS:GDC-0334 is a TRPA1 antagonist useful in treatment TRPA1-mediated diseases, such as pain or asthma.Formula:C24H19F8N5O3SColor and Shape:SolidMolecular weight:609.5AQP4 (201-220)
CAS:AQP4 (201-220) is the encephalitogenic epitope of AQP-4. AQP4 (201-220) can induce experimental autoimmune encephalomyelitis (EAE), characterized by midline brain lesions, retinal lesions, and lesions at the gray matter/white matter boundary of the spinal cord. AQP-4 is the target antigen in neuromyelitis optica.Formula:C97H143N27O27SColor and Shape:SolidMolecular weight:2151.4GaTx2
CAS:High-affinity ClC-2 blocker (KD ~50 pM), selective over other ClCs/CFTR/GABAC/CaCC/KV1.2; slows activation, no effect on open channels.Formula:C125H199N39O47S6Purity:98%Color and Shape:SolidMolecular weight:3192.54
