CFTR
CFTR is a chloride channel protein that regulates the transport of chloride and bicarbonate ions across epithelial cell membranes, playing a crucial role in maintaining fluid balance in tissues. Mutations in the CFTR gene lead to cystic fibrosis, a genetic disorder characterized by the production of thick mucus that can clog airways and lead to severe respiratory and digestive problems. At CymitQuimica, we provide a selection of CFTR modulators to support your research in cystic fibrosis, ion transport, and genetic disorders.
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Elexacaftor
CAS:2216712-66-0
Elexacaftor (VX-445) is a cystic fibrosis transmembrane conductance regulator (CFTR) corrector.Cost-effective and quality-assured.
Formula:
C26H34F3N7O4S
Purity:
98.87% - 99.87%
Color and Shape:
Solid
Molecular weight:
597.65
Ref: TM-T14935
| 1mg | 96.00 € | ||
| 2mg | 138.00 € | ||
| 5mg | 291.00 € | ||
| 10mg | 461.00 € | ||
| 25mg | 754.00 € | ||
| 50mg | 1,056.00 € | ||
| 100mg | 1,417.00 € | ||
| 1mL*10mM (DMSO) | 365.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Glibenclamide
CAS:10238-21-8
Glibenclamide (Glyburide) is an antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide.
Formula:
C23H28ClN3O5S
Purity:
99.1% - 99.77%
Color and Shape:
Solid
Molecular weight:
494
Ref: TM-T1634
| 1g | 62.00 € | ||
| 500mg | 54.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
WAY-326766
CAS:853138-67-7
WAY-326766 increases ion transport through mutant CFTR and can be used to alter the lifespan …
Formula:
C21H23N3O5
Purity:
98.76%
Color and Shape:
Solid
Molecular weight:
397.42
Ref: TM-T77604
| 1mg | 78.00 € | ||
| 5mg | 171.00 € | ||
| 10mg | 272.00 € | ||
| 25mg | 547.00 € | ||
| 50mg | 780.00 € | ||
| 100mg | 1,077.00 € | ||
| 500mg | 2,162.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
(R)-BPO-27
CAS:1415390-47-4
(R)-BPO-27 is an orally active and potent ATP-competitive CFTR inhibitor (IC50: 4 nM) for the …
Formula:
C26H18BrN3O6
Purity:
99.1%
Color and Shape:
Solid
Molecular weight:
548.34
Ref: TM-T10591L
| 1mg | 142.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Nesolicaftor
CAS:1953130-87-4
Nesolicaftor (PTI-428) specifically enhances cystic fibrosis transmembrane conductance regulator protein synthesis.
Formula:
C18H18N4O4
Purity:
98.64%
Color and Shape:
Solid
Molecular weight:
354.36
Ref: TM-T16681
| 1mg | 97.00 € | ||
| 5mg | 217.00 € | ||
| 10mg | 381.00 € | ||
| 25mg | 657.00 € | ||
| 50mg | 936.00 € | ||
| 100mg | 1,266.00 € | ||
| 1mL*10mM (DMSO) | 239.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Tezacaftor
CAS:1152311-62-0
Tezacaftor (VX661) is a small molecule that can be used as a corrector of the …
Formula:
C26H27F3N2O6
Purity:
100% - 99.69%
Color and Shape:
Solid
Molecular weight:
520.5
Ref: TM-T2263
| 1mg | 40.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 81.00 € | ||
| 10mg | 121.00 € | ||
| 25mg | 208.00 € | ||
| 50mg | 337.00 € | ||
| 100mg | 494.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
CFTR(inh)-172
CAS:307510-92-5
CFTR(inh)-172 (CFTR Inhibitor-172) is a voltage-independent, selective CFTR inhibitor.
Formula:
C18H10F3NO3S2
Purity:
98% - 99.94%
Color and Shape:
Solid
Molecular weight:
409.4
Ref: TM-T2355
| 1mg | 35.00 € | ||
| 2mg | 50.00 € | ||
| 5mg | 71.00 € | ||
| 10mg | 100.00 € | ||
| 25mg | 189.00 € | ||
| 50mg | 357.00 € | ||
| 100mg | 523.00 € | ||
| 1mL*10mM (DMSO) | 69.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Lumacaftor
CAS:936727-05-8
Lumacaftor (VRT 826809) is a CFTR modulator that corrects the folding and trafficking of CFTR …
Formula:
C24H18F2N2O5
Purity:
99.68% - 99.72%
Color and Shape:
Solid
Molecular weight:
452.41
Ref: TM-T2595
| 5mg | 51.00 € | ||
| 10mg | 66.00 € | ||
| 25mg | 81.00 € | ||
| 50mg | 95.00 € | ||
| 100mg | 120.00 € | ||
| 500mg | 291.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
GlyH-101
CAS:328541-79-3
GlyH-101 is a cell-permeable glycinyl hydrazone compound that blocks CFTR with Ki of 1.4 uM.
Formula:
C19H15Br2N3O3
Purity:
98.31% - 98.71%
Color and Shape:
Solid
Molecular weight:
493.15
Ref: TM-T2451
| 1mg | 40.00 € | ||
| 2mg | 51.00 € | ||
| 5mg | 84.00 € | ||
| 10mg | 119.00 € | ||
| 25mg | 243.00 € | ||
| 50mg | 485.00 € | ||
| 100mg | 680.00 € | ||
| 200mg | 897.00 € | ||
| 1mL*10mM (DMSO) | 92.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Ivacaftor
CAS:873054-44-5
Ivacaftor (VX-770) (VX-770) is a potentiator of CFTR targeting G551D-CFTR (EC50: 100 nM) and F508del-CFTR …
Formula:
C24H28N2O3
Purity:
99% - 99.98%
Color and Shape:
Solid
Molecular weight:
392.49
Ref: TM-T2588
| 1mg | 38.00 € | ||
| 5mg | 80.00 € | ||
| 10mg | 124.00 € | ||
| 25mg | 202.00 € | ||
| 50mg | 297.00 € | ||
| 100mg | 445.00 € | ||
| 500mg | 975.00 € | ||
| 1mL*10mM (DMSO) | 89.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
PPQ-102
CAS:931706-15-9
PPQ-102 (CFTR Inhibitor), an effective CFTR inhibitor, can completely inhibit CFTR chloride current (IC50: 90 …
Formula:
C26H22N4O3
Purity:
99.17% - ≥95%
Color and Shape:
Solid
Molecular weight:
438.48
Ref: TM-T1874
| 1mg | 40.00 € | ||
| 2mg | 51.00 € | ||
| 5mg | 83.00 € | ||
| 10mg | 132.00 € | ||
| 25mg | 263.00 € | ||
| 50mg | 508.00 € | ||
| 100mg | 732.00 € | ||
| 1mL*10mM (DMSO) | 93.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
GLPG1837
CAS:1654725-02-6
GLPG1837 (ABBV-974) is an effective CFTR potentiator, with EC50s of 3 nM and 339 nM …
Formula:
C16H20N4O3S
Purity:
98.75% - 99.73%
Color and Shape:
Solid
Molecular weight:
348.42
Ref: TM-T7083
| 1mg | 36.00 € | ||
| 5mg | 79.00 € | ||
| 10mg | 119.00 € | ||
| 25mg | 184.00 € | ||
| 50mg | 346.00 € | ||
| 100mg | 527.00 € | ||
| 200mg | 739.00 € | ||
| 1mL*10mM (DMSO) | 86.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
CFTR corrector 2
CAS:1628416-28-3
CFTR corrector 2 (FDL169) is a novel and potent CFTR corrector for treating cystic fibrosis …
Formula:
C27H23FN4O4
Purity:
99.66%
Color and Shape:
Solid
Molecular weight:
486.49
Ref: TM-T5312
| 2mg | 38.00 € | ||
| 5mg | 56.00 € | ||
| 10mg | 82.00 € | ||
| 25mg | 150.00 € | ||
| 50mg | 218.00 € | ||
| 100mg | 323.00 € | ||
| 200mg | 451.00 € | ||
| 1mL*10mM (DMSO) | 61.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
IOWH-032
CAS:1191252-49-9
IOWH-032 (IOWH032) , a synthetic CFTR inhibitor, has been investigated for the treatment of cholera, …
Formula:
C22H15Br2N3O4
Purity:
100% - ≥95%
Color and Shape:
Solid
Molecular weight:
545.18
Ref: TM-T2486
| 10mg | 63.00 € | ||
| 25mg | 96.00 € | ||
| 50mg | 146.00 € | ||
| 100mg | 218.00 € | ||
| 1mL*10mM (DMSO) | 48.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
KM11060
CAS:774549-97-2
KM11060 is a novel corrector of the F508del-CFTR trafficking defect, Correcting F508del-CFTR trafficking, increasing the …
Formula:
C19H17Cl2N3O2S
Purity:
98.86%
Color and Shape:
Solid
Molecular weight:
422.33
Ref: TM-T3135
| 10mg | 56.00 € | ||
| 25mg | 99.00 € | ||
| 50mg | 176.00 € | ||
| 100mg | 296.00 € | ||
| 1mL*10mM (DMSO) | 36.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Icenticaftor
CAS:1334546-77-8
Icenticaftor (QBW251) is an orally active potentiator of CFTR channel.
Formula:
C12H13F6N3O3
Purity:
98.39%
Color and Shape:
Solid
Molecular weight:
361.24
Ref: TM-T9499
| 1mg | 155.00 € | ||
| 5mg | 318.00 € | ||
| 10mg | 477.00 € | ||
| 25mg | 762.00 € | ||
| 50mg | 1,071.00 € | ||
| 100mg | 1,519.00 € | ||
| 200mg | 2,059.00 € | ||
| 1mL*10mM (DMSO) | 252.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Ataluren
CAS:775304-57-9
Ataluren (PTC124) is a novel, orally administered drug that targets nonsense mutations.
Formula:
C15H9FN2O3
Purity:
99.45% - 99.84%
Color and Shape:
Solid
Molecular weight:
284.24
Ref: TM-T1805
| 5mg | 38.00 € | ||
| 10mg | 56.00 € | ||
| 25mg | 92.00 € | ||
| 50mg | 122.00 € | ||
| 100mg | 184.00 € | ||
| 200mg | 221.00 € | ||
| 500mg | 370.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Steviol
CAS:471-80-7
1.
Formula:
C20H30O3
Purity:
98% - 99.92%
Color and Shape:
Solid
Molecular weight:
318.45
Ref: TM-T2S1837
| 1mg | 52.00 € | ||
| 2mg | 67.00 € | ||
| 5mg | 93.00 € | ||
| 10mg | 159.00 € | ||
| 25mg | 258.00 € | ||
| 50mg | 385.00 € | ||
| 1mL*10mM (DMSO) | 97.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
SRI-37240
CAS:883956-47-6
SRI-37240 suppresses CFTR nonsense mutations, aids in fixing premature termination codons, works with G418.
Formula:
C24H23N3O2
Purity:
98.73%
Color and Shape:
Liquid
Molecular weight:
385.46
Ref: TM-T61702
| 1mg | 42.00 € | ||
| 5mg | 89.00 € | ||
| 10mg | 126.00 € | ||
| 25mg | 206.00 € | ||
| 50mg | 307.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
CFTR corrector 9
CAS:909861-78-5
CFTR corrector 9 is a CF modulator used to research cystic fibrosis and related disorders.
Formula:
C16H14N2O4
Purity:
98.24%
Color and Shape:
Solid
Molecular weight:
298.29
Ref: TM-T60653
| 1mg | 48.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 149.00 € | ||
| 25mg | 292.00 € | ||
| 50mg | 438.00 € | ||
| 100mg | 625.00 € | ||
| 500mg | 1,290.00 € | ||
| 1mL*10mM (DMSO) | 92.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
