CFTR
CFTR is a chloride channel protein that regulates the transport of chloride and bicarbonate ions across epithelial cell membranes, playing a crucial role in maintaining fluid balance in tissues. Mutations in the CFTR gene lead to cystic fibrosis, a genetic disorder characterized by the production of thick mucus that can clog airways and lead to severe respiratory and digestive problems. At CymitQuimica, we provide a selection of CFTR modulators to support your research in cystic fibrosis, ion transport, and genetic disorders.
Found 66 products of "CFTR"
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Elexacaftor
CAS:Elexacaftor (VX-445) is a cystic fibrosis transmembrane conductance regulator (CFTR) corrector.Cost-effective and quality-assured.Formula:C26H34F3N7O4SPurity:98.87% - 99.87%Color and Shape:SolidMolecular weight:597.65Ref: TM-T14935
1mg93.00€2mg130.00€5mg230.00€10mg371.00€25mg730.00€50mg1,018.00€100mg1,369.00€1mL*10mM (DMSO)304.00€Glibenclamide
CAS:Glibenclamide (Glyburide) is an antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide.Formula:C23H28ClN3O5SPurity:99.05% - 99.75%Color and Shape:SolidMolecular weight:494.00(Rac)-Tezacaftor
CAS:(Rac)-Tezacaftor, a racemate, corrects F508del CFTR for cystic fibrosis research.Formula:C26H27F3N2O6Color and Shape:SolidMolecular weight:520.5kCAL01
CAS:kCAL01 is a CAL inhibitor with a Ki value of 2.3 μM and holds potential for research in cystic fibrosis (CF).Formula:C36H57N11O9Color and Shape:SolidMolecular weight:787.91Crofelemer
CAS:Crofelemer (Provir) is an orally active antidiarrheal agent. It targets the cystic fibrosis transmembrane conductance regulator (CFTR) and calcium-activated chloride channels (CACC), which are responsible for chloride and fluid secretion in the gastrointestinal tract. Crofelemer is applicable for research in diarrhea-related conditions.Color and Shape:SolidWAY-326766
CAS:WAY-326766 increases ion transport through mutant CFTR and can be used to alter the lifespan of eukaryotes.WAY-326766 can be used to treat cystic fibrosis (CF).Formula:C21H23N3O5Purity:99.87%Color and Shape:SolidMolecular weight:397.42Vanzacaftor
CAS:Vanzacaftor is a CFTR modulator improving protein processing and surface trafficking, restoring chloride transport and aiding cystic fibrosis therapy research.Formula:C32H39N7O4SPurity:99.14%Color and Shape:SolidMolecular weight:617.76Astressin 2B
CAS:CRF2 antagonist with IC50 of 1.3 nM; >500 nM for CRF1. Aids gastric emptying.Formula:C183H307N49O53Purity:98%Color and Shape:SolidMolecular weight:4041.69(R)-Crinecerfont
CAS:4-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1A)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-(2-propyn-1-yl)-2-thiazolamine is an enantiomericFormula:C27H28ClFN2OSPurity:99.02%Color and Shape:SoildMolecular weight:483.04Ref: TM-T60126
1mg109.00€2mg163.00€5mg241.00€10mg355.00€25mg532.00€50mg745.00€100mg1,018.00€500mgTo inquire1mL*10mM (DMSO)289.00€H2-Gamendazole
CAS:H2-Gamendazole: inhibits spermatogenesis, cancer therapy, targets heat shock proteins & EF1α, regulates Hsp90.Formula:C18H13Cl2F3N2O2Purity:97.39%Color and Shape:SolidMolecular weight:417.21Ref: TM-T72076
1mg73.00€5mg180.00€10mg269.00€25mg477.00€50mg642.00€100mg880.00€200mg1,161.00€1mL*10mM (DMSO)203.00€CFTR activator 2
CAS:CFTR activator 2 (WAY-326769) is an activator of mutant CFTR (cystic fibrosis transmembrane conductance regulator), which increases ion transport activity and can be used for research into cystic fibrosis (CF).Formula:C27H27N3O3Purity:99.70%Color and Shape:SolidMolecular weight:441.52Zatonacaftor
CAS:Zatonacaftor, a cystic fibrosis transmembrane regulator (CFTR) modulator, is utilized in the research of cystic fibrosis [1] [2].Formula:C24H27N3O4SColor and Shape:SolidMolecular weight:453.55Cavosonstat
CAS:Cavosonstat (N91115) is an oral GSNOR inhibitor aiding CFTR in cystic fibrosis.Formula:C16H10ClNO3Purity:99.64%Color and Shape:SolidMolecular weight:299.71CP-628006
CAS:CP-628006 is a small molecule CFTR potentiator that effectively restores ATP-dependent channel gating to G551D-CFTR, the mutant form found in cystic fibrosis.Formula:C32H35F3N2O2Color and Shape:SolidMolecular weight:536.639Crinecerfont hydrochloride
CAS:SSR-125543, a potent CRF1 receptor non-peptide antagonist, effective in CAH research, taken orally.Formula:C27H29Cl2FN2OSColor and Shape:SolidMolecular weight:519.5KM11060
CAS:KM11060 is a novel corrector of the F508del-CFTR trafficking defect, Correcting F508del-CFTR trafficking, increasing the amount of functional CFTR at the plasmaFormula:C19H17Cl2N3O2SPurity:98.86%Color and Shape:SolidMolecular weight:422.33Icenticaftor
CAS:Icenticaftor (QBW251) is an orally active potentiator of CFTR channel.Formula:C12H13F6N3O3Purity:99.76%Color and Shape:SolidMolecular weight:361.24Ref: TM-T9499
1mg152.00€5mg313.00€10mg469.00€25mg750.00€50mg1,054.00€100mg1,494.00€200mg2,025.00€1mL*10mM (DMSO)248.00€Tezacaftor
CAS:Tezacaftor (VX661) is a small molecule that can be used as a corrector of the cystic fibrosis transmembrane conductance regulator (CFTR) gene function.Formula:C26H27F3N2O6Purity:98.84% - >99.99%Color and Shape:SolidMolecular weight:520.5Ref: TM-T2263
1mg40.00€2mg52.00€5mg82.00€10mg123.00€25mg212.00€50mg343.00€100mg505.00€1mL*10mM (DMSO)88.00€IOWH-032
CAS:IOWH-032 (IOWH032) , a synthetic CFTR inhibitor, has been investigated for the treatment of cholera, diarrhea, and secretory diarrhea.Formula:C22H15Br2N3O4Purity:98.92% - ≥95%Color and Shape:SolidMolecular weight:545.18Ataluren
CAS:Ataluren (PTC124) is a novel, orally administered drug that targets nonsense mutations.Formula:C15H9FN2O3Purity:99.16% - 99.84%Color and Shape:SolidMolecular weight:284.24Ref: TM-T1805
5mg35.00€10mg54.00€25mg88.00€50mg117.00€100mg178.00€200mg213.00€500mg359.00€1mL*10mM (DMSO)46.00€
