TRP/TRPV Channel
TRP (Transient Receptor Potential) channels, including the TRPV subfamily, are a group of ion channels involved in various sensory processes, such as temperature sensation, pain perception, and osmoregulation. TRP channels are widely expressed in different tissues and play a role in physiological responses to environmental stimuli. The TRPV channels, in particular, are involved in detecting temperature changes and are implicated in conditions such as chronic pain, inflammation, and cancer. At CymitQuimica, we offer a comprehensive range of TRP/TRPV channel modulators to support your research in sensory biology, pain management, and signal transduction.
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Mavatrep
CAS:956274-94-5
Mavatrep (JNJ-39439335) is a selective antagonist of TRPV1 with Ki of 6.5 nM and can …
Formula:
C25H21F3N2O
Purity:
98.01% - 98.38%
Color and Shape:
Solid
Molecular weight:
422.44
Ref: TM-T16014
| 1mg | 65.00 € | ||
| 5mg | 143.00 € | ||
| 10mg | 225.00 € | ||
| 25mg | 449.00 € | ||
| 50mg | 724.00 € | ||
| 100mg | 1,154.00 € | ||
| 500mg | 2,312.00 € | ||
| 1mL*10mM (DMSO) | 158.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
MSP3
CAS:1820968-63-5
MSP3 is an agonist of TRPV1 (EC50 = 0.87 μM) and shows antinociceptive and neuroprotective …
Formula:
C16H19NO3S
Purity:
99.46%
Color and Shape:
Solid
Molecular weight:
305.39
Ref: TM-T28118
| 2mg | 34.00 € | ||
| 5mg | 51.00 € | ||
| 10mg | 82.00 € | ||
| 25mg | 164.00 € | ||
| 50mg | 247.00 € | ||
| 100mg | 364.00 € | ||
| 200mg | 515.00 € | ||
| 1mL*10mM (DMSO) | 72.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
TRPV4 agonist-1
CAS:2314467-60-0
TRPV4 agonist-1 is an agonist of TRPV4 (EC50: 60 nM in the hTRPV4 Ca2+ assay).
Formula:
C25H23ClF2N4O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
484.93
Ref: TM-T13214
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
HC-070
CAS:1628291-95-1
HC-070 is a TRPC5 and TRPC4 antagonist (IC50 = 9.3 nM and 46 nM).
Formula:
C22H20Cl2N4O4
Purity:
97.06%
Color and Shape:
Solid
Molecular weight:
475.32
Ref: TM-T15465
| 1mg | 131.00 € | ||
| 5mg | 271.00 € | ||
| 10mg | 427.00 € | ||
| 25mg | 707.00 € | ||
| 50mg | 994.00 € | ||
| 100mg | 1,341.00 € | ||
| 1mL*10mM (DMSO) | 277.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
TC-I 2014
CAS:1221349-53-6
TC-I 2014 shows antiallodynic properties in pain models.
Formula:
C23H19F6N3O
Purity:
98.75%
Color and Shape:
Solid
Molecular weight:
467.41
Ref: TM-T17006
| 1mg | 113.00 € | ||
| 5mg | 270.00 € | ||
| 10mg | 402.00 € | ||
| 25mg | 644.00 € | ||
| 50mg | 909.00 € | ||
| 100mg | 1,201.00 € | ||
| 500mg | 2,432.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
TRPM4-IN-2
CAS:667411-04-3
NBA, or TRPM4-IN-2, is a potent TRPM4 inhibitor with IC50 of 0.16 μM, used in …
Formula:
C19H14ClNO4
Purity:
99.21%
Color and Shape:
Liquid
Molecular weight:
355.77
Ref: TM-T61275
| 2mg | To inquire |
Estimated delivery in United States, on Wednesday 22 Jan 2025
JYL 1421
CAS:401907-26-4
JYL 1421 (SC 0030) is an antagonist of TRPV1 receptor (IC50 = 8 nM).
Formula:
C20H26FN3O2S2
Color and Shape:
Solid
Molecular weight:
423.57
Ref: TM-T15634
| 25mg | 710.00 € | ||
| 50mg | 934.00 € | ||
| 100mg | 1,470.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
Elismetrep
CAS:1400699-64-0
Elismetrep (MT-8554) is an orally available TRPM8 inhibitor with potential analgesic activity for the study …
Formula:
C27H21F3N2O5S
Purity:
99.57% - 99.86%
Color and Shape:
Solid
Molecular weight:
542.53
Ref: TM-T27253
| 1mg | 123.00 € | ||
| 5mg | 294.00 € | ||
| 10mg | 459.00 € | ||
| 25mg | 916.00 € | ||
| 50mg | 1,368.00 € | ||
| 100mg | 1,846.00 € | ||
| 200mg | 2,492.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
RN9893
CAS:1803003-68-0
RN9893 is a selective and potent TRPV4 receptor antagonist with IC50 values of 320, 420 …
Formula:
C21H23F3N4O5S
Purity:
99.89%
Color and Shape:
Solid
Molecular weight:
500.49
Ref: TM-T28548
| 1mg | 46.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 141.00 € | ||
| 25mg | 268.00 € | ||
| 50mg | 397.00 € | ||
| 100mg | 578.00 € | ||
| 500mg | 1,187.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
AMG-0347
CAS:946615-43-6
AMG-0347 inhibits TRPA1 ion channels in sensory neurons, blocking pain perception.
Formula:
C24H26F3N3O2
Purity:
99.7%
Color and Shape:
Solid
Molecular weight:
445.48
Ref: TM-T29968
| 1mg | 369.00 € | ||
| 5mg | 901.00 € | ||
| 10mg | 1,205.00 € | ||
| 25mg | 1,818.00 € | ||
| 50mg | 2,443.00 € | ||
| 100mg | 3,291.00 € | ||
| 1mL*10mM (DMSO) | 939.00 € |
Estimated delivery in United States, on Wednesday 5 Feb 2025
A-1165442
CAS:1221443-94-2
A-1165442 is a competitive TRPV1 antagonist. For human TRPV, the IC50 values is 9 nM.
Formula:
C22H20ClF2N3O2
Color and Shape:
Solid
Molecular weight:
431.86
Ref: TM-T14067
| 5mg | 341.00 € | ||
| 25mg | 1,382.00 € | ||
| 50mg | 1,816.00 € | ||
| 100mg | 2,602.00 € |
Estimated delivery in United States, on Wednesday 5 Feb 2025
MK-2295
CAS:878811-00-8
MK-2295 is a potent TRPV1 antagonist. MK-2295 can be used in studies about the treatment …
Formula:
C27H31FN6O2
Purity:
98.1% - 98.83%
Color and Shape:
Solid
Molecular weight:
490.57
Ref: TM-T33429
| 1mg | 113.00 € | ||
| 5mg | 244.00 € | ||
| 10mg | 360.00 € | ||
| 25mg | 550.00 € | ||
| 50mg | 769.00 € | ||
| 100mg | 1,031.00 € | ||
| 500mg | 2,070.00 € |
Estimated delivery in United States, on Wednesday 5 Feb 2025
A 425619
CAS:581809-67-8
A 425619 (1-(4-(TRIFLUOROMETHYL)BENZYL)-3-(ISOQUINOLIN-5-YL)UREA) is a potent TRPV1 antagonist
Formula:
C18H14F3N3O
Purity:
99.35%
Color and Shape:
Solid
Molecular weight:
345.32
Ref: TM-T8562
| 1mg | 85.00 € | ||
| 5mg | 169.00 € | ||
| 10mg | 249.00 € | ||
| 25mg | 410.00 € | ||
| 50mg | 577.00 € | ||
| 100mg | 780.00 € | ||
| 200mg | 1,034.00 € | ||
| 1mL*10mM (DMSO) | 172.00 € |
Estimated delivery in United States, on Wednesday 5 Feb 2025
PF-05105679
CAS:1398583-31-7
PF-05105679 is a selective TRPM8 antagonist (IC50 = 103 nM). PF-05105679 can be used in …
Formula:
C26H21FN2O3
Purity:
99.82%
Color and Shape:
Solid
Molecular weight:
428.45
Ref: TM-T16483
| 1mg | 48.00 € | ||
| 2mg | 64.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 159.00 € | ||
| 25mg | 302.00 € | ||
| 50mg | 467.00 € | ||
| 100mg | 701.00 € | ||
| 200mg | 926.00 € | ||
| 500mg | 1,412.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Wednesday 5 Feb 2025
GSK3395879
CAS:2215852-91-6
GSK3395879 is a selective and orally bioavailable antagonist of transient receptor potential vanilloid-4 (TRPV4) (IC50: …
Formula:
C20H15F4N3O5S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
485.41
Ref: TM-T15439
| 25mg | 1,967.00 € | ||
| 50mg | 2,598.00 € | ||
| 100mg | 3,458.00 € |
Estimated delivery in United States, on Wednesday 5 Feb 2025
Mesendogen
CAS:864716-85-8
Mesendogen is an inhibitor of transient receptor potential cation channel, subfamily M, member 6 (TRPM6) …
Formula:
C18H16ClF3N2OS
Purity:
98.90%
Color and Shape:
Solid
Molecular weight:
400.85
Ref: TM-T28020
| 1mg | 42.00 € | ||
| 5mg | 90.00 € | ||
| 10mg | 143.00 € | ||
| 25mg | 300.00 € | ||
| 50mg | 523.00 € | ||
| 100mg | 736.00 € | ||
| 1mL*10mM (DMSO) | 103.00 € |
Estimated delivery in United States, on Wednesday 5 Feb 2025
JT010
CAS:917562-33-5
JT010 is an effective agonist of TRPA1 (EC50 = 0.65 nM).
Formula:
C16H19ClN2O3S
Purity:
98.5%
Color and Shape:
Solid
Molecular weight:
354.85
Ref: TM-T15628
| 2mg | 34.00 € | ||
| 5mg | 51.00 € | ||
| 10mg | 82.00 € | ||
| 25mg | 150.00 € | ||
| 50mg | 232.00 € | ||
| 100mg | 346.00 € | ||
| 1mL*10mM (DMSO) | 56.00 € |
Estimated delivery in United States, on Wednesday 5 Feb 2025
AMG2850
CAS:1470018-52-0
AMG2850 is a potent, orally bioavailable, and selective antagonist of transient receptor potential melastatin 8 …
Formula:
C19H17F6N3O
Purity:
99.05%
Color and Shape:
Solid
Molecular weight:
417.35
Ref: TM-T10300
| 1mg | 72.00 € | ||
| 5mg | 164.00 € | ||
| 10mg | 239.00 € | ||
| 25mg | 430.00 € | ||
| 50mg | 638.00 € | ||
| 100mg | 818.00 € | ||
| 1mL*10mM (DMSO) | 175.00 € |
Estimated delivery in United States, on Wednesday 19 Feb 2025
TRPA1 Antagonist 1
CAS:1984825-08-2
TRPA1 Antagonist 1 is an antagonist of TRPA1(IC50: 8 nM) and is a methylene phosphate …
Formula:
C24H22F6N5Na2O7PS
Purity:
98%
Color and Shape:
Solid
Molecular weight:
715.47
Ref: TM-T13212
| 25mg | 3,079.00 € | ||
| 50mg | 4,094.00 € | ||
| 100mg | 5,701.00 € |
Estimated delivery in United States, on Wednesday 5 Mar 2025
GSK2798745
CAS:1419609-94-1
GSK2798745 is an orally active transient receptor potential vanilloid 4 (TRPV4) ion channel blocker (IC50s: …
Formula:
C25H28N6O3
Color and Shape:
Solid
Molecular weight:
460.53
Ref: TM-T15434
| 25mg | 2,106.00 € | ||
| 50mg | 2,789.00 € | ||
| 100mg | 3,744.00 € |
Estimated delivery in United States, on Wednesday 5 Mar 2025
