TRP/TRPV Channel
TRP (Transient Receptor Potential) channels, including the TRPV subfamily, are a group of ion channels involved in various sensory processes, such as temperature sensation, pain perception, and osmoregulation. TRP channels are widely expressed in different tissues and play a role in physiological responses to environmental stimuli. The TRPV channels, in particular, are involved in detecting temperature changes and are implicated in conditions such as chronic pain, inflammation, and cancer. At CymitQuimica, we offer a comprehensive range of TRP/TRPV channel modulators to support your research in sensory biology, pain management, and signal transduction.
Found 92 products of "TRP/TRPV Channel"
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Olvanil
CAS:<p>Olvanil (N-Vannilyloleoylamide) is a vanilloid receptor agonist with EC50 of 0.7nM.</p>Formula:C26H43NO3Purity:99.58%Color and Shape:SolidMolecular weight:417.62FEMA-4809
CAS:<p>FEMA-4809 activates TRPM8, the ion channel for cold sensation, and is used as a cooling agent.</p>Formula:C17H17N3O2SPurity:99.9%Color and Shape:SolidMolecular weight:327.4Mesendogen
CAS:<p>Mesendogen is an inhibitor of transient receptor potential cation channel, subfamily M, member 6 (TRPM6) and 7 (TRPM7) and acts by inhibiting TRPM6/TRPM7</p>Formula:C18H16ClF3N2OSPurity:99.66%Color and Shape:SolidMolecular weight:400.85MK-2295
CAS:<p>MK-2295 is a potent TRPV1 antagonist. MK-2295 can be used in studies about the treatment of chronic pain.</p>Formula:C27H31FN6O2Purity:98.83% - 99.44%Color and Shape:SolidMolecular weight:490.57A-1165442
CAS:<p>A-1165442 is a competitive TRPV1 antagonist. For human TRPV, the IC50 values is 9 nM.</p>Formula:C22H20ClF2N3O2Color and Shape:SolidMolecular weight:431.86GSK3395879
CAS:<p>GSK3395879 is a selective and orally bioavailable antagonist of transient receptor potential vanilloid-4 (TRPV4) (IC50: 1 nM for hTRPV4).</p>Formula:C20H15F4N3O5SPurity:98%Color and Shape:SolidMolecular weight:485.41PF-05105679
CAS:<p>PF-05105679 is a selective TRPM8 antagonist (IC50 = 103 nM). PF-05105679 can be used in research on cold-related pain.</p>Formula:C26H21FN2O3Purity:99.84%Color and Shape:SolidMolecular weight:428.45JT010
CAS:<p>JT010 is an effective agonist of TRPA1 (EC50 = 0.65 nM).</p>Formula:C16H19ClN2O3SPurity:99.75%Color and Shape:SolidMolecular weight:354.85AMG-0347
CAS:<p>AMG-0347 inhibits TRPA1 ion channels in sensory neurons, blocking pain perception.</p>Formula:C24H26F3N3O2Purity:99.93%Color and Shape:SolidMolecular weight:445.48AMG2850
CAS:<p>AMG2850 is a potent, orally bioavailable, and selective antagonist of transient receptor potential melastatin 8 (TRPM8).</p>Formula:C19H17F6N3OPurity:99.84%Color and Shape:SolidMolecular weight:417.35TRPA1 Antagonist 1
CAS:<p>TRPA1 Antagonist 1 is an antagonist of TRPA1(IC50: 8 nM) and is a methylene phosphate prodrug which converts to its active parent drug.</p>Formula:C24H20F6N5Na2O7PSPurity:98%Color and Shape:SolidMolecular weight:713.45Apcin A HCL
CAS:<p>Apcin A HCL is an Apcin derivative. Apcin A HCL is an anaphase-promoting complex (APC) inhibitor. Apcin-A HCL interacts strongly with Cdc20, and inhibits the ubiquitination of Cdc20 substrates. Apcin-A HCL can be used to synthesize the PROTAC CP5V [1].</p>Formula:C10H15Cl4N5O2Purity:99.30%Color and Shape:SolidMolecular weight:379.07
