TRP/TRPV Channel
TRP (Transient Receptor Potential) channels, including the TRPV subfamily, are a group of ion channels involved in various sensory processes, such as temperature sensation, pain perception, and osmoregulation. TRP channels are widely expressed in different tissues and play a role in physiological responses to environmental stimuli. The TRPV channels, in particular, are involved in detecting temperature changes and are implicated in conditions such as chronic pain, inflammation, and cancer. At CymitQuimica, we offer a comprehensive range of TRP/TRPV channel modulators to support your research in sensory biology, pain management, and signal transduction.
Found 92 products of "TRP/TRPV Channel"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
(Z)-Capsaicin
CAS:<p>(Z)-Capsaicin (Zucapsaicin) is a medication used to treat osteoarthritis of the knee and Others neuropathic pain.(Z)-Capsaicin is a synthetic cis isomer of</p>Formula:C18H27NO3Purity:97.33% - 98.91%Color and Shape:SolidMolecular weight:305.41TRPV4 agonist-1 free base
CAS:<p>TRPV4 agonist-1 free base (OUN67600) is an agonist of transient receptor potential vanilloid 4 (TRPV4;EC50 of 60 nM, in the hTRPV4 Ca2+ assay).</p>Formula:C25H22F2N4O2Purity:99.79%Color and Shape:SolidMolecular weight:448.46GFB-8438
CAS:<p>GFB-8438 is a potent and subtype selective inhibitor of TRPC5(IC50s of 0.18 and 0.29 μM of hTRPC5 and hTRPC4, respectively).</p>Formula:C16H14ClF3N4O2Purity:99.58%Color and Shape:SolidMolecular weight:386.76BI-749327
CAS:<p>BI-749327 is a high selectivity and orally bioavailable antagonist of TRPC6 (IC50s: 13 nM, 19 nM and 15 nM for mouse, human and guinea pig TRPC6).</p>Formula:C23H21F3N4O2Purity:99.68%Color and Shape:SolidMolecular weight:442.43IA-Alkyne
CAS:<p>IA-Alkyne: TRPC agonist, cysteine-reactivity probe, potential in respiratory infection study.</p>Formula:C8H12INOPurity:99.76%Color and Shape:SolidMolecular weight:265.09Vocacapsaicin hydrochloride
CAS:<p>Vocacapsaicin hydrochloride (CA-008 hydrochloride) is a non-opioid TRPV1 agonist, a raw material for capsaicin, and is used for pain relief.</p>Formula:C26H42ClN3O4Purity:99.66% - 99.80%Color and Shape:SolidMolecular weight:496.08NGD-8243
CAS:<p>NGD-8243 (N-[4-(trifluoromethyl)phenyl]-7-[3-(trifluoromethyl)pyridin-2-yl]quinazolin-4-amine) is a TRPV1 inhibitor and can be used in studies for prevention</p>Formula:C21H12F6N4Purity:95.26%Color and Shape:SolidMolecular weight:434.34AP 18
CAS:<p>AP-18 is a potent and selective TRPA1 inhibitor.</p>Formula:C11H12ClNOPurity:99.85% - 99.96%Color and Shape:SolidMolecular weight:209.67GSK2798745
CAS:<p>GSK2798745 is an orally active transient receptor potential vanilloid 4 (TRPV4) ion channel blocker (IC50s: 1.8 and 1.6 nM for hTRPV4 and rTRPV4).</p>Formula:C25H28N6O3Color and Shape:SolidMolecular weight:460.53RN-1665
CAS:<p>RN-1665 is a potent and selective TRPV4 receptor antagonist.</p>Formula:C20H24F5N3O3S2Purity:>99.99%Color and Shape:SoildMolecular weight:513.54CBP-1008
<p>CBP-1008 is a dual-ligand peptide-drug conjugate (PDC) with MMAE, targeting folate receptor (FRα) and TRPV6. It exhibits high binding affinity to FRα and low affinity to TRPV6. CBP-1008 shows antitumor activity and can be utilized for research in advanced solid tumors such as colorectal cancer, breast cancer, non-small cell lung cancer, ovarian cancer, adrenocortical carcinoma, and follicular dendritic cell sarcoma.</p>Color and Shape:Odour Solid(S)-ABT 102
CAS:<p>N-[(1S)-1H-inden-1-yl]-N'-indazol-4-ylurea is a strong TRPV1 blocker with a 123 nM IC50 against capsaicin.</p>Formula:C21H24N4OPurity:99.65% - 99.77%Color and Shape:SoildMolecular weight:348.44PF-04745637
CAS:<p>PF-04745637 is a potent and selective TRPA1 antagonist with an IC50 of 17 nM[1].</p>Formula:C27H32ClF3N2O2Purity:98.88% - 99.3%Color and Shape:SolidMolecular weight:509TRPA1-IN-2
CAS:<p>TRPA1-IN-2 is a potent and orally active TRPA1 inhibitor with an IC50 value of 0.04 µM.TRPA1-IN-2 has anti-inflammatory activity.</p>Formula:C24H25F3N4OPurity:98.05%Color and Shape:SoildMolecular weight:442.48Resolvin D2
CAS:<p>Resolvin D2 (RvD2) is a TRPV1 inhibitor and pro-ablative mediator with anti-inflammatory, anti-infective and pro-ablative effects.</p>Formula:C22H32O5Purity:98%Color and Shape:SolidMolecular weight:376.49TRPM8 antagonist 3
CAS:<p>TRPM8 antagonist 3 is a blocker of TRPM8 (IC50 = 11 nM).</p>Formula:C13H12N2O4SPurity:99.74%Color and Shape:SolidMolecular weight:292.31Oleoyl Serotonin
CAS:<p>Oleoyl Serotonin is an antagonist of hTRPV1 with an IC50 of 2.57 μM.</p>Formula:C28H44N2O2Purity:99.88%Color and Shape:SolidMolecular weight:440.66L-R4W2
CAS:<p>Vanilloid TRPV1 (VR1) receptor antagonist peptide (IC50 ~ 0.1 μM); blocks Ca2+ currents in dorsal root ganglion neurons. Analgesic in vivo.</p>Formula:C46H71N21O6Purity:98%Color and Shape:SolidMolecular weight:1014.2Phenazopyridine
CAS:<p>Phenazopyridine is an orally administered azo dye with local analgesic effects on urinary tract infections,. against SARM1 and TRPM8.</p>Formula:C11H11N5Purity:99.98%Color and Shape:SolidMolecular weight:213.24BTD
CAS:<p>BTD is a TRPC5 activator that activates heteromeric channel complexes composed of TRPC5 and its closest relatives TRPC1 or TRPC4.</p>Formula:C24H33N3O4SColor and Shape:SolidMolecular weight:459.6
