TRP/TRPV Channel
TRP (Transient Receptor Potential) channels, including the TRPV subfamily, are a group of ion channels involved in various sensory processes, such as temperature sensation, pain perception, and osmoregulation. TRP channels are widely expressed in different tissues and play a role in physiological responses to environmental stimuli. The TRPV channels, in particular, are involved in detecting temperature changes and are implicated in conditions such as chronic pain, inflammation, and cancer. At CymitQuimica, we offer a comprehensive range of TRP/TRPV channel modulators to support your research in sensory biology, pain management, and signal transduction.
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M084
CAS:51314-51-3
M084 (N-Butyl-1H-benzimidazol-2-amine) is a blocker of TRPC4/5 channel, with antidepressant and anxiolytic effects.
Formula:
C11H15N3
Purity:
99.84%
Color and Shape:
Solid
Molecular weight:
189.26
Ref: TM-T8607
| 1mg | 88.00 € | ||
| 5mg | 170.00 € | ||
| 10mg | 259.00 € | ||
| 25mg | 425.00 € | ||
| 50mg | 598.00 € | ||
| 100mg | 810.00 € | ||
| 200mg | 1,074.00 € | ||
| 1mL*10mM (DMSO) | 145.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
M8-B Hydrochloride
CAS:883976-12-3
M8-B Hydrochloride is a selective transient receptor potential melastatin-8 (TRPM8) channel antagonist.
Formula:
C22H25ClN2O3S
Purity:
99.33%
Color and Shape:
Solid
Molecular weight:
432.96
Ref: TM-T8442
| 2mg | 35.00 € | ||
| 5mg | 52.00 € | ||
| 10mg | 74.00 € | ||
| 25mg | 145.00 € | ||
| 50mg | 226.00 € | ||
| 100mg | 335.00 € | ||
| 200mg | 469.00 € | ||
| 1mL*10mM (DMSO) | 64.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
SB-366791
CAS:472981-92-3
SB-366791 is a new and selective cinnamide TRPV1 antagonist.
Formula:
C16H14ClNO2
Purity:
99.12%
Color and Shape:
Solid
Molecular weight:
287.74
Ref: TM-T6977
| 5mg | 35.00 € | ||
| 10mg | 46.00 € | ||
| 25mg | 88.00 € | ||
| 50mg | 126.00 € | ||
| 100mg | 202.00 € | ||
| 200mg | 299.00 € | ||
| 1mL*10mM (DMSO) | 35.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
RQ-00203078
CAS:1254205-52-1
RQ-00203078 is a highly selective, potent and orally available TRPM8 antagonist.
Formula:
C21H13ClF6N2O5S
Purity:
98% - 99.17%
Color and Shape:
Solid
Molecular weight:
554.85
Ref: TM-T2007
| 5mg | 50.00 € | ||
| 10mg | 79.00 € | ||
| 25mg | 124.00 € | ||
| 50mg | 187.00 € | ||
| 100mg | 350.00 € | ||
| 1mL*10mM (DMSO) | 58.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
A-967079
CAS:1170613-55-4
A 967079 is a potent, selective, and bioavailable inhibitor of the TRPA1 channel, with IC50 …
Formula:
C12H14FNO
Purity:
98.34% - 99.75%
Color and Shape:
Solid
Molecular weight:
207.24
Ref: TM-T7205
| 5mg | 55.00 € | ||
| 10mg | 74.00 € | ||
| 25mg | 147.00 € | ||
| 50mg | 250.00 € | ||
| 100mg | 427.00 € | ||
| 1mL*10mM (DMSO) | 65.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
AMG 517
CAS:659730-32-2
AMG 517 is an effective and specific TRPV1 antagonist, antagonizes proton (IC50: 0.76 nM), capsaicin …
Formula:
C20H13F3N4O2S
Purity:
99.66% - 99.85%
Color and Shape:
Solid
Molecular weight:
430.4
Ref: TM-T6379
| 5mg | 51.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 187.00 € | ||
| 50mg | 354.00 € | ||
| 100mg | 528.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
ICILIN
CAS:36945-98-9
ICILIN (AG-3-5) is a synthetic TRPM8 ion channel super-agonist.
Formula:
C16H13N3O4
Purity:
97.61% - ≥95%
Color and Shape:
Light Yellow Solid
Molecular weight:
311.29
Ref: TM-T1814
| 5mg | 37.00 € | ||
| 10mg | 57.00 € | ||
| 25mg | 97.00 € | ||
| 50mg | 172.00 € | ||
| 100mg | 296.00 € | ||
| 1mL*10mM (DMSO) | 40.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
BCTC
CAS:393514-24-4
BCTC is a potent TRPV1 antagonist that inhibits capsaicin-induced and acid-induced activation of rat TRPV1 …
Formula:
C20H25ClN4O
Purity:
≥95%
Color and Shape:
Solid
Molecular weight:
372.89
Ref: TM-T7102
| 5mg | 37.00 € | ||
| 10mg | 48.00 € | ||
| 25mg | 89.00 € | ||
| 50mg | 153.00 € | ||
| 100mg | 221.00 € | ||
| 200mg | 329.00 € | ||
| 1mL*10mM (DMSO) | 42.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
HC-067047
CAS:883031-03-6
HC-067047 is a potent and selective TRPV4 antagonist.Also inhibits the endogenous TRPV4-mediated response to 4α-PDH …
Formula:
C26H28F3N3O2
Purity:
99.45% - 99.79%
Color and Shape:
Solid
Molecular weight:
471.51
Ref: TM-T4680
| 1mg | 35.00 € | ||
| 5mg | 67.00 € | ||
| 10mg | 97.00 € | ||
| 25mg | 188.00 € | ||
| 50mg | 311.00 € | ||
| 100mg | 502.00 € | ||
| 1mL*10mM (DMSO) | 67.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
AM-0902
CAS:1883711-97-4
AM-0902 is a potent and specific TRPA1 antagonist (IC50s: 71/131 nM for rTRPA1 and hTRPA1).
Formula:
C17H15ClN6O2
Purity:
100%
Color and Shape:
Solid
Molecular weight:
370.79
Ref: TM-T7430
| 2mg | 35.00 € | ||
| 5mg | 50.00 € | ||
| 10mg | 70.00 € | ||
| 25mg | 131.00 € | ||
| 50mg | 246.00 € | ||
| 100mg | 364.00 € | ||
| 200mg | 517.00 € | ||
| 1mL*10mM (DMSO) | 56.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
Pyr6
CAS:245747-08-4
Pyr6 (N-[4-[3,5-Bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-3-fluoro-4-pyridinecarboxamide) is a selective TRPC3 inhibitor with IC50 of 0.49 uM(Ca2+ influx
Formula:
C17H9F7N4O
Purity:
99.18%
Color and Shape:
Solid
Molecular weight:
418.27
Ref: TM-T16688
| 5mg | 37.00 € | ||
| 10mg | 57.00 € | ||
| 25mg | 94.00 € | ||
| 50mg | 126.00 € | ||
| 1mL*10mM (DMSO) | 42.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
SB 452533
CAS:459429-39-1
SB 452533 is an antagonist of the vanilloid receptor 1(pKb: 7.8).
Formula:
C18H22BrN3O
Purity:
98.52%
Color and Shape:
Solid
Molecular weight:
376.29
Ref: TM-T23322
| 2mg | 42.00 € | ||
| 5mg | 64.00 € | ||
| 10mg | 97.00 € | ||
| 25mg | 183.00 € | ||
| 50mg | 284.00 € | ||
| 100mg | 411.00 € | ||
| 200mg | 585.00 € | ||
| 1mL*10mM (DMSO) | 85.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
ASP7663
CAS:1190217-35-6
ASP7663 is a TRPA1 Receptor Agonist and exhibiting an abdominal analgesic effect in vivo.
Formula:
C14H14FNO3
Purity:
98.11%
Color and Shape:
Solid
Molecular weight:
263.26
Ref: TM-T8410
| 1mg | 39.00 € | ||
| 5mg | 82.00 € | ||
| 10mg | 111.00 € | ||
| 25mg | 217.00 € | ||
| 50mg | 330.00 € | ||
| 100mg | 497.00 € | ||
| 1mL*10mM (DMSO) | 90.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
Pico145
CAS:1628287-16-0
Pico145 (HC-608) is a remarkable inhibitor of TRPC1/4/5 channels.
Formula:
C23H20ClF3N4O5
Purity:
99.06%
Color and Shape:
Solid
Molecular weight:
524.88
Ref: TM-T16532
| 1mg | 116.00 € | ||
| 5mg | 276.00 € | ||
| 10mg | 434.00 € | ||
| 25mg | 715.00 € | ||
| 50mg | 1,008.00 € | ||
| 100mg | 1,359.00 € | ||
| 1mL*10mM (DMSO) | 315.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
TRPM4-IN-1
CAS:351424-20-9
TRPM4-IN-1 (4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid) is a potent and selective inhibitor of TRPM4 with an IC50 of …
Formula:
C15H11Cl2NO4
Purity:
97.22%
Color and Shape:
Solid
Molecular weight:
340.16
Ref: TM-T9245
| 5mg | 46.00 € | ||
| 10mg | 66.00 € | ||
| 25mg | 131.00 € | ||
| 50mg | 215.00 € | ||
| 100mg | 344.00 € | ||
| 200mg | 502.00 € | ||
| 1mL*10mM (DMSO) | 73.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
MK6-83
CAS:1062271-24-2
MK6-83 is the transient receptor potential channel ML3 agonist.
Formula:
C16H20N2O2S2
Purity:
99.71%
Color and Shape:
Solid
Molecular weight:
336.47
Ref: TM-T24477
| 2mg | 48.00 € | ||
| 5mg | 72.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 187.00 € | ||
| 50mg | 328.00 € | ||
| 100mg | 560.00 € | ||
| 1mL*10mM (DMSO) | 80.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
9-Phenanthrol
CAS:484-17-3
9-Phenanthrol is inhibitor of the transient receptor potential melastatin 4 (TRPM) channel, a Ca2+ -activated …
Formula:
C14H10O
Purity:
98.72%
Color and Shape:
Solid
Molecular weight:
194.23
Ref: TM-T22537
| 25mg | 48.00 € | ||
| 50mg | 58.00 € | ||
| 100mg | 84.00 € | ||
| 200mg | 109.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
TC-I2000
CAS:1159996-20-9
TC-I2000 is an TRPM8 channel blocker. Inhibits icilin-induced TRPM8 channel activation in rTRPM8-expressing CHO cells …
Formula:
C23H18F4N2O
Purity:
98.87%
Color and Shape:
Liquid
Molecular weight:
414.4
Ref: TM-T8449
| 5mg | 35.00 € | ||
| 10mg | 50.00 € | ||
| 25mg | 88.00 € | ||
| 50mg | 119.00 € | ||
| 100mg | 173.00 € | ||
| 200mg | 259.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
Ononetin
CAS:487-49-0
Ononetin (2',4'-Dihydroxy-2-(4-methoxyphenyl)acetophenone) is a TRPM3 channel blocker(IC50: 0.3 μM).
Formula:
C15H14O4
Purity:
98.15%
Color and Shape:
Solid
Molecular weight:
258.27
Ref: TM-T23107
| 5mg | 51.00 € | ||
| 10mg | 79.00 € | ||
| 25mg | 137.00 € | ||
| 50mg | 188.00 € | ||
| 100mg | 283.00 € | ||
| 200mg | 432.00 € | ||
| 500mg | 700.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
AC1903
CAS:831234-13-0
AC1903 is a specific inhibitor of TRPC5 channel, and has been shown to suppress severe …
Formula:
C19H17N3O
Purity:
98.45%
Color and Shape:
Solid
Molecular weight:
303.36
Ref: TM-T8528
| 5mg | 48.00 € | ||
| 10mg | 70.00 € | ||
| 25mg | 127.00 € | ||
| 50mg | 202.00 € | ||
| 100mg | 303.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
