TRP/TRPV Channel
TRP (Transient Receptor Potential) channels, including the TRPV subfamily, are a group of ion channels involved in various sensory processes, such as temperature sensation, pain perception, and osmoregulation. TRP channels are widely expressed in different tissues and play a role in physiological responses to environmental stimuli. The TRPV channels, in particular, are involved in detecting temperature changes and are implicated in conditions such as chronic pain, inflammation, and cancer. At CymitQuimica, we offer a comprehensive range of TRP/TRPV channel modulators to support your research in sensory biology, pain management, and signal transduction.
Found 98 products for "TRP/TRPV Channel".
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(S)-ABT 102
CAS:N-[(1S)-1H-inden-1-yl]-N'-indazol-4-ylurea is a strong TRPV1 blocker with a 123 nM IC50 against capsaicin.Formula:C21H24N4OPurity:99.65% - 99.77%Color and Shape:White SolidMolecular weight:348.44Ref: TM-T29522L
1mg73.00€5mg149.00€1mL*10mM (DMSO)154.00€10mg212.00€25mg319.00€50mg447.00€100mg610.00€200mg822.00€BTD
CAS:BTD is a TRPC5 activator that activates heteromeric channel complexes composed of TRPC5 and its closest relatives TRPC1 or TRPC4.Formula:C24H33N3O4SColor and Shape:SolidMolecular weight:459.6Phenamil methanesulfonate
CAS:Phenamil methanesulfonate is a potent analog of Amiloride that functions as a strong and less reversible epithelial sodium channel (ENaC) blocker with an IC50 of 400 nM, Phenamil methanesulfonate also acts as a competitive inhibitor of TRPP3 and suppressing TRPP3-mediated calcium transport with an IC50 of 140 nM in Ca2+ uptake assays. Phenamil methanesulfonate robustly activates BMP signaling to promote bone repair, supporting its use in cystic fibrosis lung disease, ion channel biology, and regenerative medicine research.Formula:C13H16ClN7O4SPurity:98.33%Color and Shape:SolidMolecular weight:401.83Phenazopyridine
CAS:Phenazopyridine is an orally administered azo dye with local analgesic effects on urinary tract infections,. against SARM1 and TRPM8.Formula:C11H11N5Purity:99.98%Color and Shape:Orange SolidMolecular weight:213.24HC067047 Hydrochloride(883031-03-6 free base)
CAS:HC-067047 hydrochloride, a TRPV4 antagonist, selectively inhibits human, rat, and mouse currents with IC50s: 486 nM, 133 nM, and 17 nM.Formula:C26H29ClF3N3O2Purity:99.95%Color and Shape:SolidMolecular weight:507.98Ref: TM-T4680L
1mg84.00€5mg168.00€1mL*10mM (DMSO)207.00€10mg245.00€25mg404.00€50mg567.00€100mg767.00€200mg1,018.00€TC-I2000
CAS:TC-I2000 is an TRPM8 channel blocker. Inhibits icilin-induced TRPM8 channel activation in rTRPM8-expressing CHO cells with IC50 of 53 nM.Formula:C23H18F4N2OPurity:99.77%Color and Shape:White SolidMolecular weight:414.49-Phenanthrol
CAS:9-Phenanthrol is inhibitor of the transient receptor potential melastatin 4 (TRPM) channel, a Ca2+ -activated non-selective cation channel.Formula:C14H10OPurity:98.48%Color and Shape:Yellow SolidMolecular weight:194.23ML204 hydrochloride
CAS:ML204 hydrochloride (ML204 HCl) is a TRPC4/TRPC5 channel antagonist.Formula:C15H19ClN2Color and Shape:Yellow SolidMolecular weight:262.78RQ-00203078
CAS:RQ-00203078 is a highly selective, potent and orally available TRPM8 antagonist.Formula:C21H13ClF6N2O5SPurity:98% - 99.6%Color and Shape:SolidMolecular weight:554.85A-967079
CAS:A 967079 is a potent, selective, and bioavailable inhibitor of the TRPA1 channel, with IC50 values of 67 and 289 nM for the human and rat isoforms, respectivelyFormula:C12H14FNOPurity:98.34% - 99.92%Color and Shape:SolidMolecular weight:207.24WS-12
CAS:WS-12 is a potent TRPM8 agonist that acts as a cooling agent (EC50 : 193 nM)Formula:C18H27NO2Purity:99.99%Color and Shape:White SolidMolecular weight:289.41Evifacotrep
CAS:Evifacotrep: TRPC5 antagonist for neurological disease research (WO2020061162, compound 100).Formula:C18H12ClF4N5O2Purity:98.6%Color and Shape:SolidMolecular weight:441.77Ref: TM-T40042
1mg92.00€1mL*10mM (DMSO)152.00€5mg178.00€10mg286.00€25mg440.00€50mg655.00€100mg973.00€200mg1,468.00€Chembridge-5861528
CAS:Chembridge-5861528 (TCS 5861528) is a TRPA1 channel blocker that antagonizes AITC- and 4-HNE-evoked calcium influx with IC50 values of 14.3 and 18.7 μM.Formula:C19H23N5O3Purity:99.97%Color and Shape:SolidMolecular weight:369.42PF-4840154
CAS:PF-4840154: potent TrpA1 agonist; EC50 of 97 nM (rat) & 23 nM (human); triggers nociception in mice.Formula:C26H38N6O2Purity:>99.99%Color and Shape:White SolidMolecular weight:466.62Ref: TM-T4385
1mg84.00€5mg152.00€1mL*10mM (DMSO)157.00€10mg236.00€25mg394.00€50mg618.00€100mg1,009.00€Pico145
CAS:Pico145 (HC-608) is a remarkable inhibitor of TRPC1/4/5 channels.Formula:C23H20ClF3N4O5Purity:99.06%Color and Shape:SolidMolecular weight:524.88Ref: TM-T16532
1mg70.00€5mg150.00€1mL*10mM (DMSO)167.00€10mg215.00€25mg358.00€50mg517.00€100mg707.00€200mg1,009.00€TRPM4-IN-1
CAS:TRPM4-IN-1 (4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid) is a potent and selective inhibitor of TRPM4 with an IC50 of 1.5 μM.Formula:C15H11Cl2NO4Purity:97.22%Color and Shape:SolidMolecular weight:340.16AMG 333
CAS:AMG 333 is TRPM8 antagonist with an IC50 of 13 nM,a Clinical Candidate for the Treatment of Migraine.Formula:C20H12F5N3O4Purity:99.95%Color and Shape:SolidMolecular weight:453.32SB-366791
CAS:SB-366791 is a new and selective cinnamide TRPV1 antagonist.Formula:C16H14ClNO2Purity:99.51%Color and Shape:White SolidMolecular weight:287.74RN-1734
CAS:RN-1734 is selective TRPV4 channel antagonist(IC50 of 2.3 μM,5.9 μM,3.2 μM for hTRPV4, mTRPV4 and rTRPV4,respectively)Formula:C14H22Cl2N2O2SPurity:99.1% - 99.3%Color and Shape:SolidMolecular weight:353.31SB 452533
CAS:SB 452533 is an antagonist of the vanilloid receptor 1(pKb: 7.8).Formula:C18H22BrN3OPurity:99.87%Color and Shape:SolidMolecular weight:376.29Ref: TM-T23322
2mg39.00€5mg60.00€1mL*10mM (DMSO)73.00€10mg92.00€25mg173.00€50mg269.00€100mg389.00€200mg555.00€
