TRP/TRPV Channel
TRP (Transient Receptor Potential) channels, including the TRPV subfamily, are a group of ion channels involved in various sensory processes, such as temperature sensation, pain perception, and osmoregulation. TRP channels are widely expressed in different tissues and play a role in physiological responses to environmental stimuli. The TRPV channels, in particular, are involved in detecting temperature changes and are implicated in conditions such as chronic pain, inflammation, and cancer. At CymitQuimica, we offer a comprehensive range of TRP/TRPV channel modulators to support your research in sensory biology, pain management, and signal transduction.
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AMG 333
CAS:1416799-28-4
AMG 333 is TRPM8 antagonist with an IC50 of 13 nM,a Clinical Candidate for the …
Formula:
C20H12F5N3O4
Purity:
99.95%
Color and Shape:
Solid
Molecular weight:
453.32
Ref: TM-T5479
| 1mg | 37.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 79.00 € | ||
| 10mg | 126.00 € | ||
| 25mg | 245.00 € | ||
| 50mg | 393.00 € | ||
| 100mg | 560.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
M8-B Hydrochloride
CAS:883976-12-3
M8-B Hydrochloride is a selective transient receptor potential melastatin-8 (TRPM8) channel antagonist.
Formula:
C22H25ClN2O3S
Purity:
99.33%
Color and Shape:
Solid
Molecular weight:
432.96
Ref: TM-T8442
| 2mg | 35.00 € | ||
| 5mg | 52.00 € | ||
| 10mg | 74.00 € | ||
| 25mg | 145.00 € | ||
| 50mg | 226.00 € | ||
| 100mg | 335.00 € | ||
| 200mg | 469.00 € | ||
| 1mL*10mM (DMSO) | 64.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
Chembridge-5861528
CAS:332117-28-9
Chembridge-5861528 (TCS 5861528) is a TRPA1 channel blocker that antagonizes AITC- and 4-HNE-evoked calcium influx …
Formula:
C19H23N5O3
Purity:
100%
Color and Shape:
Solid
Molecular weight:
369.42
Ref: TM-T2711
| 5mg | 42.00 € | ||
| 10mg | 62.00 € | ||
| 25mg | 111.00 € | ||
| 50mg | 170.00 € | ||
| 100mg | 264.00 € | ||
| 200mg | 378.00 € | ||
| 1mL*10mM (DMSO) | 46.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
cim0216
CAS:1031496-06-6
CIM0216 is a synthetic TRPM3 activator whose potency and apparent affinity greatly exceeds that of …
Formula:
C21H21N3O2
Purity:
99.87%
Color and Shape:
Solid
Molecular weight:
347.41
Ref: TM-T9263
| 1mg | 47.00 € | ||
| 2mg | 59.00 € | ||
| 5mg | 92.00 € | ||
| 10mg | 145.00 € | ||
| 25mg | 298.00 € | ||
| 50mg | 465.00 € | ||
| 100mg | 702.00 € | ||
| 500mg | 1,454.00 € | ||
| 1mL*10mM (DMSO) | 92.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
ML204
CAS:5465-86-1
ML204 is a novel potent antagonist that selectively modulates native TRPC4/C5 ion channels.
Formula:
C15H18N2
Purity:
98.1% - 99.98%
Color and Shape:
Solid
Molecular weight:
226.32
Ref: TM-T2298
| 2mg | 35.00 € | ||
| 5mg | 50.00 € | ||
| 10mg | 74.00 € | ||
| 25mg | 111.00 € | ||
| 50mg | 145.00 € | ||
| 100mg | 220.00 € | ||
| 200mg | 284.00 € | ||
| 500mg | 467.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
RN-1734
CAS:946387-07-1
RN-1734 is selective TRPV4 channel antagonist(IC50 of 2.3 μM,5.9 μM,3.2 μM for hTRPV4, mTRPV4 and …
Formula:
C14H22Cl2N2O2S
Purity:
99.1% - 99.30%
Color and Shape:
Solid
Molecular weight:
353.31
Ref: TM-T7572
| 10mg | 48.00 € | ||
| 25mg | 90.00 € | ||
| 50mg | 129.00 € | ||
| 100mg | 195.00 € | ||
| 200mg | 280.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
TRPM4-IN-1
CAS:351424-20-9
TRPM4-IN-1 (4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid) is a potent and selective inhibitor of TRPM4 with an IC50 of …
Formula:
C15H11Cl2NO4
Purity:
97.22%
Color and Shape:
Solid
Molecular weight:
340.16
Ref: TM-T9245
| 5mg | 46.00 € | ||
| 10mg | 66.00 € | ||
| 25mg | 131.00 € | ||
| 50mg | 215.00 € | ||
| 100mg | 344.00 € | ||
| 200mg | 502.00 € | ||
| 1mL*10mM (DMSO) | 73.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
MK6-83
CAS:1062271-24-2
MK6-83 is the transient receptor potential channel ML3 agonist.
Formula:
C16H20N2O2S2
Purity:
99.71%
Color and Shape:
Solid
Molecular weight:
336.47
Ref: TM-T24477
| 2mg | 48.00 € | ||
| 5mg | 72.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 187.00 € | ||
| 50mg | 328.00 € | ||
| 100mg | 560.00 € | ||
| 1mL*10mM (DMSO) | 80.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
9-Phenanthrol
CAS:484-17-3
9-Phenanthrol is inhibitor of the transient receptor potential melastatin 4 (TRPM) channel, a Ca2+ -activated …
Formula:
C14H10O
Purity:
98.72%
Color and Shape:
Solid
Molecular weight:
194.23
Ref: TM-T22537
| 25mg | 48.00 € | ||
| 50mg | 58.00 € | ||
| 100mg | 84.00 € | ||
| 200mg | 109.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
TC-I2000
CAS:1159996-20-9
TC-I2000 is an TRPM8 channel blocker. Inhibits icilin-induced TRPM8 channel activation in rTRPM8-expressing CHO cells …
Formula:
C23H18F4N2O
Purity:
98.87%
Color and Shape:
Liquid
Molecular weight:
414.4
Ref: TM-T8449
| 5mg | 35.00 € | ||
| 10mg | 50.00 € | ||
| 25mg | 88.00 € | ||
| 50mg | 119.00 € | ||
| 100mg | 173.00 € | ||
| 200mg | 259.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
ML204 hydrochloride
CAS:2070015-10-8
ML204 hydrochloride (ML204 HCl) is a TRPC4/TRPC5 channel antagonist.
Formula:
C15H19ClN2
Color and Shape:
Solid
Molecular weight:
262.78
Ref: TM-T24481
| 2mg | 54.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
WS-12
CAS:68489-09-8
WS-12 is a potent TRPM8 agonist that acts as a cooling agent (EC50 : 193 …
Formula:
C18H27NO2
Purity:
99.99%
Color and Shape:
Whitish To White Solid Crystalline
Molecular weight:
289.41
Ref: TM-T7416
| 1mg | 35.00 € | ||
| 5mg | 74.00 € | ||
| 10mg | 99.00 € | ||
| 25mg | 169.00 € | ||
| 50mg | 212.00 € | ||
| 100mg | 275.00 € | ||
| 500mg | 677.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
Pyr10
CAS:1315323-00-2
Pyr10, a pyrazole derivative, selectively inhibits TRPC3, not STIM1/Orai1, with IC50 of 0.72 μM in …
Formula:
C18H13F6N3O2S
Purity:
99.69% - 99.70%
Color and Shape:
Solid
Molecular weight:
449.37
Ref: TM-T16686
| 5mg | 38.00 € | ||
| 10mg | 58.00 € | ||
| 25mg | 111.00 € | ||
| 50mg | 197.00 € | ||
| 100mg | 283.00 € | ||
| 1mL*10mM (DMSO) | 42.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
SN 2
CAS:823218-99-1
SN 2 is a novel and potent TRPML3 ion channel activator(EC50 = 1.13 μM). SN …
Formula:
C17H21NO
Purity:
99.20%
Color and Shape:
Solid
Molecular weight:
255.35
Ref: TM-T12941
| 5mg | 52.00 € | ||
| 10mg | 75.00 € | ||
| 25mg | 149.00 € | ||
| 50mg | 283.00 € | ||
| 100mg | 415.00 € | ||
| 200mg | 582.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
SB-705498
CAS:501951-42-4
SB705498 is a TRPV1 antagonist for hTRPV1. SB-705498 has been investigated for the treatment of …
Formula:
C17H16BrF3N4O
Purity:
99.16% - ≥95%
Color and Shape:
Solid
Molecular weight:
429.23
Ref: TM-T6660
| 5mg | 48.00 € | ||
| 10mg | 84.00 € | ||
| 25mg | 167.00 € | ||
| 50mg | 304.00 € | ||
| 100mg | 437.00 € | ||
| 200mg | 610.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
ML-SA1
CAS:332382-54-4
ML-SA1 (Mucolipin synthetic agonist 1) is a selective TRPML agonist, inhibits DENV2 and ZIKV by …
Formula:
C22H22N2O3
Purity:
99.28%
Color and Shape:
Solid
Molecular weight:
362.42
Ref: TM-T23004
| 5mg | 51.00 € | ||
| 10mg | 81.00 € | ||
| 25mg | 152.00 € | ||
| 50mg | 244.00 € | ||
| 100mg | 364.00 € | ||
| 200mg | 550.00 € | ||
| 1mL*10mM (DMSO) | 66.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
GSK2193874
CAS:1336960-13-4
GSK2193874 was identified as a selective, orally active TRPV4 blocker.
Formula:
C37H38BrF3N4O
Purity:
98.79% - ≥95%
Color and Shape:
Solid
Molecular weight:
691.62
Ref: TM-T5640
| 1mg | 43.00 € | ||
| 2mg | 57.00 € | ||
| 5mg | 81.00 € | ||
| 10mg | 127.00 € | ||
| 25mg | 246.00 € | ||
| 50mg | 404.00 € | ||
| 100mg | 602.00 € | ||
| 1mL*10mM (DMSO) | 111.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
Vanilloid receptor antagonist 1
CAS:871814-52-7
Vanilloid receptor antagonist 1 (4-(7-Hydroxy-2-isopropyl-4-oxoquinazolin-3(4H)-yl)benzonitrile) is a potent vanilloid receptor TRPV1 antagonist.
Formula:
C18H15N3O2
Purity:
98.14%
Color and Shape:
Solid
Molecular weight:
305.33
Ref: TM-T9247
| 1mg | 99.00 € | ||
| 5mg | 235.00 € | ||
| 10mg | 354.00 € | ||
| 25mg | 602.00 € | ||
| 50mg | 847.00 € | ||
| 100mg | 1,206.00 € | ||
| 1mL*10mM (DMSO) | 47.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
AMG9810
CAS:545395-94-6
AMG 9810 blocks capsaicin's action on TRPV1; human IC50=24.5 nM, rat IC50=85.6 nM.
Formula:
C21H23NO3
Purity:
99.79% - 99.83%
Color and Shape:
Solid
Molecular weight:
337.41
Ref: TM-T7189
| 5mg | 50.00 € | ||
| 10mg | 62.00 € | ||
| 25mg | 116.00 € | ||
| 50mg | 205.00 € | ||
| 100mg | 359.00 € | ||
| 500mg | 838.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
Optovin
CAS:348575-88-2
Optovin is a TRPA1 activator, which is reversibly photoactivated.
Formula:
C15H13N3OS2
Purity:
100.00% - 99.16%
Color and Shape:
Solid
Molecular weight:
315.41
Ref: TM-T6617
| 1mg | 40.00 € | ||
| 2mg | 51.00 € | ||
| 5mg | 81.00 € | ||
| 10mg | 97.00 € | ||
| 25mg | 188.00 € | ||
| 50mg | 314.00 € | ||
| 100mg | 563.00 € | ||
| 200mg | 687.00 € | ||
| 1mL*10mM (DMSO) | 86.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
