TRP/TRPV Channel
TRP (Transient Receptor Potential) channels, including the TRPV subfamily, are a group of ion channels involved in various sensory processes, such as temperature sensation, pain perception, and osmoregulation. TRP channels are widely expressed in different tissues and play a role in physiological responses to environmental stimuli. The TRPV channels, in particular, are involved in detecting temperature changes and are implicated in conditions such as chronic pain, inflammation, and cancer. At CymitQuimica, we offer a comprehensive range of TRP/TRPV channel modulators to support your research in sensory biology, pain management, and signal transduction.
Found 96 products of "TRP/TRPV Channel"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
BTD
CAS:BTD is a TRPC5 activator that activates heteromeric channel complexes composed of TRPC5 and its closest relatives TRPC1 or TRPC4.Formula:C24H33N3O4SColor and Shape:SolidMolecular weight:459.6Phenazopyridine
CAS:Phenazopyridine is an orally administered azo dye with local analgesic effects on urinary tract infections,. against SARM1 and TRPM8.Formula:C11H11N5Purity:99.98%Color and Shape:SolidMolecular weight:213.24JNJ-17203212
CAS:JNJ-17203212 is a potent and selective antagonist of TRPV1 (human TRPV1 and rat TRPV1, IC50 of 65 nM and 102 nM).Formula:C17H15F6N5OPurity:99.18%Color and Shape:SolidMolecular weight:419.32HC067047 Hydrochloride(883031-03-6 free base)
CAS:HC-067047 hydrochloride, a TRPV4 antagonist, selectively inhibits human, rat, and mouse currents with IC50s: 486 nM, 133 nM, and 17 nM.Formula:C26H29ClF3N3O2Purity:99.95%Color and Shape:SolidMolecular weight:507.98Ref: TM-T4680L
1mg88.00€5mg172.00€10mg259.00€25mg425.00€50mg598.00€100mg810.00€200mg1,074.00€1mL*10mM (DMSO)217.00€ML204 hydrochloride
CAS:ML204 hydrochloride (ML204 HCl) is a TRPC4/TRPC5 channel antagonist.Formula:C15H19ClN2Color and Shape:SolidMolecular weight:262.78MK6-83
CAS:MK6-83 is the transient receptor potential channel ML3 agonist.Formula:C16H20N2O2S2Purity:99.5%Color and Shape:SolidMolecular weight:336.47RQ-00203078
CAS:RQ-00203078 is a highly selective, potent and orally available TRPM8 antagonist.Formula:C21H13ClF6N2O5SPurity:98% - 99.6%Color and Shape:SolidMolecular weight:554.85A-967079
CAS:A 967079 is a potent, selective, and bioavailable inhibitor of the TRPA1 channel, with IC50 values of 67 and 289 nM for the human and rat isoforms, respectively
Formula:C12H14FNOPurity:98.34% - 99.75%Color and Shape:SolidMolecular weight:207.24HC-030031
CAS:HC-030031 (TOSLAB 829227) is a potent TRPA1 inhibitor, which antagonizes AITC- and formalin-evoked calcium influx with IC50s of 6.2 and 5.3 μM, respectively.Formula:C18H21N5O3Purity:99.69% - ≥95%Color and Shape:SolidMolecular weight:355.39Evifacotrep
CAS:Evifacotrep: TRPC5 antagonist for neurological disease research (WO2020061162, compound 100).Formula:C18H12ClF4N5O2Purity:98.6%Color and Shape:SolidMolecular weight:441.77Ref: TM-T40042
1mg92.00€5mg178.00€10mg286.00€25mg440.00€50mg655.00€100mg973.00€200mg1,468.00€1mL*10mM (DMSO)152.00€WS-12
CAS:WS-12 is a potent TRPM8 agonist that acts as a cooling agent (EC50 : 193 nM)Formula:C18H27NO2Purity:99.99%Color and Shape:Whitish To White Solid CrystallineMolecular weight:289.41Chembridge-5861528
CAS:Chembridge-5861528 (TCS 5861528) is a TRPA1 channel blocker that antagonizes AITC- and 4-HNE-evoked calcium influx with IC50 values of 14.3 and 18.7 μM.Formula:C19H23N5O3Purity:99.97%Color and Shape:SolidMolecular weight:369.42GSK2193874
CAS:GSK2193874 was identified as a selective, orally active TRPV4 blocker.Formula:C37H38BrF3N4OPurity:99.99% - ≥95%Color and Shape:SolidMolecular weight:691.62Ref: TM-T5640
1mg43.00€2mg57.00€5mg81.00€10mg127.00€25mg246.00€50mg404.00€100mg602.00€1mL*10mM (DMSO)111.00€Pyr10
CAS:Pyr10, a pyrazole derivative, selectively inhibits TRPC3, not STIM1/Orai1, with IC50 of 0.72 μM in TRPC3-HEK293, and 13.08 μM in BRL-2H3 cells.Formula:C18H13F6N3O2SPurity:99.69% - 99.7%Color and Shape:SolidMolecular weight:449.37Pico145
CAS:Pico145 (HC-608) is a remarkable inhibitor of TRPC1/4/5 channels.Formula:C23H20ClF3N4O5Purity:99.06%Color and Shape:SolidMolecular weight:524.88Ref: TM-T16532
1mg70.00€5mg150.00€10mg215.00€25mg358.00€50mg517.00€100mg707.00€200mg1,009.00€1mL*10mM (DMSO)167.00€Ononetin
CAS:Ononetin (2',4'-Dihydroxy-2-(4-methoxyphenyl)acetophenone) is a TRPM3 channel blocker(IC50: 0.3 μM).Formula:C15H14O4Purity:98.06%Color and Shape:SolidMolecular weight:258.27TRPM4-IN-1
CAS:TRPM4-IN-1 (4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid) is a potent and selective inhibitor of TRPM4 with an IC50 of 1.5 μM.Formula:C15H11Cl2NO4Purity:97.22%Color and Shape:SolidMolecular weight:340.16AMG 333
CAS:AMG 333 is TRPM8 antagonist with an IC50 of 13 nM,a Clinical Candidate for the Treatment of Migraine.Formula:C20H12F5N3O4Purity:99.95%Color and Shape:SolidMolecular weight:453.32PF-4840154
CAS:PF-4840154: potent TrpA1 agonist; EC50 of 97 nM (rat) & 23 nM (human); triggers nociception in mice.
Formula:C26H38N6O2Purity:>99.99%Color and Shape:SolidMolecular weight:466.629-Phenanthrol
CAS:9-Phenanthrol is inhibitor of the transient receptor potential melastatin 4 (TRPM) channel, a Ca2+ -activated non-selective cation channel.Formula:C14H10OPurity:98.48%Color and Shape:SolidMolecular weight:194.23
