TRP/TRPV Channel
TRP (Transient Receptor Potential) channels, including the TRPV subfamily, are a group of ion channels involved in various sensory processes, such as temperature sensation, pain perception, and osmoregulation. TRP channels are widely expressed in different tissues and play a role in physiological responses to environmental stimuli. The TRPV channels, in particular, are involved in detecting temperature changes and are implicated in conditions such as chronic pain, inflammation, and cancer. At CymitQuimica, we offer a comprehensive range of TRP/TRPV channel modulators to support your research in sensory biology, pain management, and signal transduction.
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HC-067047
CAS:883031-03-6
HC-067047 is a potent and selective TRPV4 antagonist.Also inhibits the endogenous TRPV4-mediated response to 4α-PDH …
Formula:
C26H28F3N3O2
Purity:
99.45% - 99.79%
Color and Shape:
Solid
Molecular weight:
471.51
Ref: TM-T4680
| 1mg | 35.00 € | ||
| 5mg | 67.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 185.00 € | ||
| 50mg | 306.00 € | ||
| 100mg | 491.00 € | ||
| 1mL*10mM (DMSO) | 68.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
AM-0902
CAS:1883711-97-4
AM-0902 is a potent and specific TRPA1 antagonist (IC50s: 71/131 nM for rTRPA1 and hTRPA1).
Formula:
C17H15ClN6O2
Purity:
100%
Color and Shape:
Solid
Molecular weight:
370.79
Ref: TM-T7430
| 2mg | 35.00 € | ||
| 5mg | 49.00 € | ||
| 10mg | 68.00 € | ||
| 25mg | 127.00 € | ||
| 50mg | 238.00 € | ||
| 100mg | 352.00 € | ||
| 200mg | 500.00 € | ||
| 1mL*10mM (DMSO) | 54.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
Pyr6
CAS:245747-08-4
Pyr6 (N-[4-[3,5-Bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-3-fluoro-4-pyridinecarboxamide) is a selective TRPC3 inhibitor with IC50 of 0.49 uM(Ca2+ influx
Formula:
C17H9F7N4O
Purity:
99.18%
Color and Shape:
Solid
Molecular weight:
418.27
Ref: TM-T16688
| 5mg | 36.00 € | ||
| 10mg | 56.00 € | ||
| 25mg | 92.00 € | ||
| 50mg | 123.00 € | ||
| 1mL*10mM (DMSO) | 41.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
SB 452533
CAS:459429-39-1
SB 452533 is an antagonist of the vanilloid receptor 1(pKb: 7.8).
Formula:
C18H22BrN3O
Purity:
98.52%
Color and Shape:
Solid
Molecular weight:
376.29
Ref: TM-T23322
| 2mg | 41.00 € | ||
| 5mg | 62.00 € | ||
| 10mg | 93.00 € | ||
| 25mg | 177.00 € | ||
| 50mg | 274.00 € | ||
| 100mg | 398.00 € | ||
| 200mg | 565.00 € | ||
| 1mL*10mM (DMSO) | 82.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
Chembridge-5861528
CAS:332117-28-9
Chembridge-5861528 (TCS 5861528) is a TRPA1 channel blocker that antagonizes AITC- and 4-HNE-evoked calcium influx …
Formula:
C19H23N5O3
Purity:
100%
Color and Shape:
Solid
Molecular weight:
369.42
Ref: TM-T2711
| 5mg | 40.00 € | ||
| 10mg | 59.00 € | ||
| 25mg | 107.00 € | ||
| 50mg | 168.00 € | ||
| 100mg | 253.00 € | ||
| 200mg | 362.00 € | ||
| 1mL*10mM (DMSO) | 44.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
PF-4840154
CAS:1332708-14-1
PF-4840154: potent TrpA1 agonist; EC50 of 97 nM (rat) & 23 nM (human); triggers nociception …
Formula:
C26H38N6O2
Purity:
98.48%
Color and Shape:
Solid
Molecular weight:
466.62
Ref: TM-T4385
| 1mg | 107.00 € | ||
| 2mg | 154.00 € | ||
| 5mg | 320.00 € | ||
| 10mg | 462.00 € | ||
| 25mg | 737.00 € | ||
| 50mg | 1,050.00 € | ||
| 100mg | 1,417.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
GSK2193874
CAS:1336960-13-4
GSK2193874 was identified as a selective, orally active TRPV4 blocker.
Formula:
C37H38BrF3N4O
Purity:
98.79% - ≥95%
Color and Shape:
Solid
Molecular weight:
691.62
Ref: TM-T5640
| 1mg | 43.00 € | ||
| 2mg | 61.00 € | ||
| 5mg | 85.00 € | ||
| 10mg | 129.00 € | ||
| 25mg | 247.00 € | ||
| 50mg | 403.00 € | ||
| 100mg | 593.00 € | ||
| 1mL*10mM (DMSO) | 111.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
JNJ-17203212
CAS:821768-06-3
JNJ-17203212 is a potent and selective antagonist of TRPV1 (human TRPV1 and rat TRPV1, IC50 …
Formula:
C17H15F6N5O
Purity:
99.94%
Color and Shape:
Solid
Molecular weight:
419.32
Ref: TM-T7526
| 2mg | 46.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 109.00 € | ||
| 25mg | 245.00 € | ||
| 50mg | 399.00 € | ||
| 100mg | 641.00 € | ||
| 1mL*10mM (DMSO) | 77.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
M8-B Hydrochloride
CAS:883976-12-3
M8-B Hydrochloride is a selective transient receptor potential melastatin-8 (TRPM8) channel antagonist.
Formula:
C22H25ClN2O3S
Purity:
99.33%
Color and Shape:
Solid
Molecular weight:
432.96
Ref: TM-T8442
| 2mg | 35.00 € | ||
| 5mg | 51.00 € | ||
| 10mg | 72.00 € | ||
| 25mg | 141.00 € | ||
| 50mg | 218.00 € | ||
| 100mg | 324.00 € | ||
| 200mg | 452.00 € | ||
| 1mL*10mM (DMSO) | 62.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
SB-366791
CAS:472981-92-3
SB-366791 is a new and selective cinnamide TRPV1 antagonist.
Formula:
C16H14ClNO2
Purity:
99.12%
Color and Shape:
Solid
Molecular weight:
287.74
Ref: TM-T6977
| 5mg | 35.00 € | ||
| 10mg | 44.00 € | ||
| 25mg | 87.00 € | ||
| 50mg | 123.00 € | ||
| 100mg | 196.00 € | ||
| 200mg | 291.00 € | ||
| 1mL*10mM (DMSO) | 35.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
Ononetin
CAS:487-49-0
Ononetin (2',4'-Dihydroxy-2-(4-methoxyphenyl)acetophenone) is a TRPM3 channel blocker(IC50: 0.3 μM).
Formula:
C15H14O4
Purity:
98.15%
Color and Shape:
Solid
Molecular weight:
258.27
Ref: TM-T23107
| 5mg | 34.00 € | ||
| 10mg | 50.00 € | ||
| 25mg | 88.00 € | ||
| 50mg | 113.00 € | ||
| 100mg | 169.00 € | ||
| 200mg | 250.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
CCG-143140
CAS:891016-02-7
CCG-143140 is a GLP-1 receptor inverse agonists.
Formula:
C23H31N3O3S
Purity:
99.75%
Color and Shape:
Solid
Molecular weight:
429.58
Ref: TM-T9226
| 2mg | 49.00 € | ||
| 5mg | 73.00 € | ||
| 10mg | 114.00 € | ||
| 25mg | 230.00 € | ||
| 50mg | 366.00 € | ||
| 100mg | 547.00 € | ||
| 1mL*10mM (DMSO) | 82.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
Linoleoyl Ethanolamide
CAS:68171-52-8
Linoleoyl Ethanolamide is an endocannabinoid agent.
Formula:
C20H37NO2
Purity:
99.97%
Color and Shape:
Solid
Molecular weight:
323.51
Ref: TM-T8425
| 1mg | 36.00 € | ||
| 5mg | 68.00 € | ||
| 10mg | 90.00 € | ||
| 25mg | 162.00 € | ||
| 50mg | 236.00 € | ||
| 100mg | 343.00 € | ||
| 200mg | 515.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
Fingolimod hydrochloride
CAS:162359-56-0
Fingolimod hydrochloride (FTY720) , a novel immune modulator, is a sphingosine 1-phosphate (S1P) antagonist (IC50: …
Formula:
C19H34ClNO2
Purity:
99.26% - 99.83%
Color and Shape:
White Solid
Molecular weight:
343.93
Ref: TM-T2539
| 50mg | 41.00 € | ||
| 100mg | 54.00 € | ||
| 200mg | 85.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
Evifacotrep
CAS:2413739-88-3
Evifacotrep: TRPC5 antagonist for neurological disease research (WO2020061162, compound 100).
Formula:
C18H12ClF4N5O2
Purity:
98.6%
Color and Shape:
Solid
Molecular weight:
441.77
Ref: TM-T40042
| 1mg | 62.00 € | ||
| 2mg | 91.00 € | ||
| 5mg | 141.00 € | ||
| 10mg | 204.00 € | ||
| 25mg | 345.00 € | ||
| 50mg | 493.00 € | ||
| 100mg | 670.00 € | ||
| 200mg | 904.00 € | ||
| 1mL*10mM (DMSO) | 155.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
HC067047 Hydrochloride(883031-03-6 free base)
CAS:1481646-76-7
HC-067047 hydrochloride, a TRPV4 antagonist, selectively inhibits human, rat, and mouse currents with IC50s: 486 …
Formula:
C26H29ClF3N3O2
Purity:
99.95%
Color and Shape:
Solid
Molecular weight:
507.98
Ref: TM-T4680L
| 1mg | 85.00 € | ||
| 5mg | 172.00 € | ||
| 10mg | 250.00 € | ||
| 25mg | 411.00 € | ||
| 50mg | 577.00 € | ||
| 100mg | 781.00 € | ||
| 200mg | 1,035.00 € | ||
| 1mL*10mM (DMSO) | 210.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
HC-030031
CAS:349085-38-7
HC-030031 (TOSLAB 829227) is a potent TRPA1 inhibitor, which antagonizes AITC- and formalin-evoked calcium influx …
Formula:
C18H21N5O3
Purity:
99.69% - ≥95%
Color and Shape:
Solid
Molecular weight:
355.39
Ref: TM-T6530
| 10mg | 50.00 € | ||
| 50mg | 94.00 € | ||
| 100mg | 143.00 € | ||
| 200mg | 182.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
ML204
CAS:5465-86-1
ML204 is a novel potent antagonist that selectively modulates native TRPC4/C5 ion channels.
Formula:
C15H18N2
Purity:
98.1% - 99.98%
Color and Shape:
Solid
Molecular weight:
226.32
Ref: TM-T2298
| 2mg | 35.00 € | ||
| 5mg | 51.00 € | ||
| 10mg | 73.00 € | ||
| 25mg | 110.00 € | ||
| 50mg | 143.00 € | ||
| 100mg | 216.00 € | ||
| 200mg | 277.00 € | ||
| 500mg | 458.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
RN-1734
CAS:946387-07-1
RN-1734 is selective TRPV4 channel antagonist(IC50 of 2.3 μM,5.9 μM,3.2 μM for hTRPV4, mTRPV4 and …
Formula:
C14H22Cl2N2O2S
Purity:
99.1% - 99.30%
Color and Shape:
Solid
Molecular weight:
353.31
Ref: TM-T7572
| 10mg | 47.00 € | ||
| 25mg | 88.00 € | ||
| 50mg | 125.00 € | ||
| 100mg | 188.00 € | ||
| 200mg | 271.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
AMG 333
CAS:1416799-28-4
AMG 333 is TRPM8 antagonist with an IC50 of 13 nM,a Clinical Candidate for the …
Formula:
C20H12F5N3O4
Purity:
99.95%
Color and Shape:
Solid
Molecular weight:
453.32
Ref: TM-T5479
| 5mg | 50.00 € | ||
| 10mg | 82.00 € | ||
| 25mg | 145.00 € | ||
| 50mg | 227.00 € | ||
| 100mg | 323.00 € | ||
| 200mg | 453.00 € | ||
| 1mL*10mM (DMSO) | 50.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
