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TRP/TRPV Channel

TRP/TRPV Channel

TRP (Transient Receptor Potential) channels, including the TRPV subfamily, are a group of ion channels involved in various sensory processes, such as temperature sensation, pain perception, and osmoregulation. TRP channels are widely expressed in different tissues and play a role in physiological responses to environmental stimuli. The TRPV channels, in particular, are involved in detecting temperature changes and are implicated in conditions such as chronic pain, inflammation, and cancer. At CymitQuimica, we offer a comprehensive range of TRP/TRPV channel modulators to support your research in sensory biology, pain management, and signal transduction.

Found 92 products of "TRP/TRPV Channel"

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  • Pico145
    Targetmol
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    Pico145

    CAS:
    <p>Pico145 (HC-608) is a remarkable inhibitor of TRPC1/4/5 channels.</p>
    Formula:C23H20ClF3N4O5
    Purity:99.06%
    Color and Shape:Solid
    Molecular weight:524.88

    Ref: TM-T16532

  • TRPM4-IN-1
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    TRPM4-IN-1

    CAS:
    <p>TRPM4-IN-1 (4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid) is a potent and selective inhibitor of TRPM4 with an IC50 of 1.5 μM.</p>
    Formula:C15H11Cl2NO4
    Purity:97.22%
    Color and Shape:Solid
    Molecular weight:340.16

    Ref: TM-T9245

  • MK6-83
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    MK6-83

    CAS:
    <p>MK6-83 is the transient receptor potential channel ML3 agonist.</p>
    Formula:C16H20N2O2S2
    Purity:99.5%
    Color and Shape:Solid
    Molecular weight:336.47

    Ref: TM-T24477

  • 9-Phenanthrol
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    9-Phenanthrol

    CAS:
    <p>9-Phenanthrol is inhibitor of the transient receptor potential melastatin 4 (TRPM) channel, a Ca2+ -activated non-selective cation channel.</p>
    Formula:C14H10O
    Purity:98.48%
    Color and Shape:Solid
    Molecular weight:194.23

    Ref: TM-T22537

  • TC-I2000
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    TC-I2000

    CAS:
    <p>TC-I2000 is an TRPM8 channel blocker. Inhibits icilin-induced TRPM8 channel activation in rTRPM8-expressing CHO cells with IC50 of 53 nM.</p>
    Formula:C23H18F4N2O
    Purity:99.778%
    Color and Shape:Solid
    Molecular weight:414.4

    Ref: TM-T8449

  • ML204 hydrochloride
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    ML204 hydrochloride

    CAS:
    <p>ML204 hydrochloride (ML204 HCl) is a TRPC4/TRPC5 channel antagonist.</p>
    Formula:C15H19ClN2
    Color and Shape:Solid
    Molecular weight:262.78

    Ref: TM-T24481

  • WS-12
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    WS-12

    CAS:
    <p>WS-12 is a potent TRPM8 agonist that acts as a cooling agent (EC50 : 193 nM)</p>
    Formula:C18H27NO2
    Purity:99.99%
    Color and Shape:Whitish To White Solid Crystalline
    Molecular weight:289.41

    Ref: TM-T7416

  • Pyr10
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    Pyr10

    CAS:
    <p>Pyr10, a pyrazole derivative, selectively inhibits TRPC3, not STIM1/Orai1, with IC50 of 0.72 μM in TRPC3-HEK293, and 13.08 μM in BRL-2H3 cells.</p>
    Formula:C18H13F6N3O2S
    Purity:99.69% - 99.7%
    Color and Shape:Solid
    Molecular weight:449.37

    Ref: TM-T16686

  • SB-705498
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    SB-705498

    CAS:
    <p>SB705498 is a TRPV1 antagonist for hTRPV1. SB-705498 has been investigated for the treatment of Rhinitis, Chronic Cough, and Non-allergic Rhinitis.</p>
    Formula:C17H16BrF3N4O
    Purity:99.57% - ≥95%
    Color and Shape:Solid
    Molecular weight:429.23

    Ref: TM-T6660

  • Vanilloid receptor antagonist 1
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    Vanilloid receptor antagonist 1

    CAS:
    <p>Vanilloid receptor antagonist 1 (4-(7-Hydroxy-2-isopropyl-4-oxoquinazolin-3(4H)-yl)benzonitrile) is a potent vanilloid receptor TRPV1 antagonist.</p>
    Formula:C18H15N3O2
    Purity:98.14%
    Color and Shape:Solid
    Molecular weight:305.33

    Ref: TM-T9247

  • AMG9810
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    AMG9810

    CAS:
    <p>AMG 9810 blocks capsaicin's action on TRPV1; human IC50=24.5 nM, rat IC50=85.6 nM.</p>
    Formula:C21H23NO3
    Purity:99.79% - 99.95%
    Color and Shape:Solid
    Molecular weight:337.41

    Ref: TM-T7189

  • Optovin
    Targetmol
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    Optovin

    CAS:
    <p>Optovin is a TRPA1 activator, which is reversibly photoactivated.</p>
    Formula:C15H13N3OS2
    Purity:99.47% - 99.67%
    Color and Shape:Solid
    Molecular weight:315.41

    Ref: TM-T6617

  • MDR-652
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    MDR-652

    CAS:
    <p>MDR-652 is a highly specific and efficacious agonist of nonpungent transient receptor potential vanilloid 1 (TRPV1) with Ki value of 11.4 nM and 23.8 nM for</p>
    Formula:C22H23ClFN3O2S
    Purity:99.96%
    Color and Shape:Solid
    Molecular weight:447.95

    Ref: TM-T22360

  • RN-1747
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    RN-1747

    CAS:
    <p>RN-1747: TRPV4 agonist (EC50: human 0.77 μM, mouse 4.0 μM, rat 4.1 μM), TRPM8 antagonist (IC50: 4 μM).</p>
    Formula:C17H18ClN3O4S
    Purity:99.29%
    Color and Shape:Solid
    Molecular weight:395.86

    Ref: TM-T16763

  • AMTB hydrochloride
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    AMTB hydrochloride

    CAS:
    <p>AMTB HCl: Novel TRPM8 blocker, relieves pain, treats urinary issues, moderates bladder reflexes in rats.</p>
    Formula:C23H27ClN2O2S
    Purity:99.08%
    Color and Shape:Solid
    Molecular weight:430.99

    Ref: TM-T19723

  • TRPM8 antagonist 2
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    TRPM8 antagonist 2

    CAS:
    <p>TRPM8 antagonist 2 is a potent and selective TRPM8 antagonist with an IC50 of 0.2 nM. TRPM8 antagonist 2 is used in the research of neuropathic pain syndromes.</p>
    Formula:C26H26N2O2
    Purity:98.1%
    Color and Shape:Solid
    Molecular weight:398.5

    Ref: TM-T5698

  • AC1903
    Targetmol
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    AC1903

    CAS:
    <p>AC1903 is a specific inhibitor of TRPC5 channel, and has been shown to suppress severe proteinuria and prevent podocyte loss.</p>
    Formula:C19H17N3O
    Purity:98.45%
    Color and Shape:Solid
    Molecular weight:303.36

    Ref: TM-T8528

  • cim0216
    Targetmol
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    cim0216

    CAS:
    <p>CIM0216 is a synthetic TRPM3 activator whose potency and apparent affinity greatly exceeds that of the canonical TRPM3 agonist.</p>
    Formula:C21H21N3O2
    Purity:99.87%
    Color and Shape:Solid
    Molecular weight:347.41

    Ref: TM-T9263

  • AMG 517
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    AMG 517

    CAS:
    <p>AMG 517 is an effective and specific TRPV1 antagonist, antagonizes proton (IC50: 0.76 nM), capsaicin (IC50: 0.62 nM) and heat activation (IC50: 1.3 nM) of TRPV1</p>
    Formula:C20H13F3N4O2S
    Purity:99.77% - 99.85%
    Color and Shape:Solid
    Molecular weight:430.4

    Ref: TM-T6379

  • JNJ-28583113
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    JNJ-28583113

    CAS:
    <p>JNJ-28583113 is a TRPM2 antagonist, inducing phosphorylation of GSK3α and β subunits, protecting cells from oxidative stress-induced cell death.</p>
    Formula:C19H21F3N2O2
    Purity:98.57%
    Color and Shape:Solid
    Molecular weight:366.38

    Ref: TM-T74779