TRP/TRPV Channel
TRP (Transient Receptor Potential) channels, including the TRPV subfamily, are a group of ion channels involved in various sensory processes, such as temperature sensation, pain perception, and osmoregulation. TRP channels are widely expressed in different tissues and play a role in physiological responses to environmental stimuli. The TRPV channels, in particular, are involved in detecting temperature changes and are implicated in conditions such as chronic pain, inflammation, and cancer. At CymitQuimica, we offer a comprehensive range of TRP/TRPV channel modulators to support your research in sensory biology, pain management, and signal transduction.
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RQ-00203078
CAS:1254205-52-1
RQ-00203078 is a highly selective, potent and orally available TRPM8 antagonist.
Formula:
C21H13ClF6N2O5S
Purity:
98% - 99.17%
Color and Shape:
Solid
Molecular weight:
554.85
Ref: TM-T2007
| 5mg | 50.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 121.00 € | ||
| 50mg | 183.00 € | ||
| 100mg | 345.00 € | ||
| 1mL*10mM (DMSO) | 58.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
A-967079
CAS:1170613-55-4
A 967079 is a potent, selective, and bioavailable inhibitor of the TRPA1 channel, with IC50 …
Formula:
C12H14FNO
Purity:
98.34% - 99.75%
Color and Shape:
Solid
Molecular weight:
207.24
Ref: TM-T7205
| 5mg | 54.00 € | ||
| 10mg | 73.00 € | ||
| 25mg | 145.00 € | ||
| 50mg | 245.00 € | ||
| 100mg | 419.00 € | ||
| 1mL*10mM (DMSO) | 65.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
Pico145
CAS:1628287-16-0
Pico145 (HC-608) is a remarkable inhibitor of TRPC1/4/5 channels.
Formula:
C23H20ClF3N4O5
Purity:
99.06%
Color and Shape:
Solid
Molecular weight:
524.88
Ref: TM-T16532
| 1mg | 114.00 € | ||
| 5mg | 271.00 € | ||
| 10mg | 427.00 € | ||
| 25mg | 699.00 € | ||
| 50mg | 984.00 € | ||
| 100mg | 1,328.00 € | ||
| 1mL*10mM (DMSO) | 314.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
TRPM4-IN-1
CAS:351424-20-9
TRPM4-IN-1 (4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid) is a potent and selective inhibitor of TRPM4 with an IC50 of …
Formula:
C15H11Cl2NO4
Purity:
97.22%
Color and Shape:
Solid
Molecular weight:
340.16
Ref: TM-T9245
| 5mg | 45.00 € | ||
| 10mg | 66.00 € | ||
| 25mg | 129.00 € | ||
| 50mg | 210.00 € | ||
| 100mg | 340.00 € | ||
| 200mg | 491.00 € | ||
| 1mL*10mM (DMSO) | 73.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
MK6-83
CAS:1062271-24-2
MK6-83 is the transient receptor potential channel ML3 agonist.
Formula:
C16H20N2O2S2
Purity:
99.71%
Color and Shape:
Solid
Molecular weight:
336.47
Ref: TM-T24477
| 5mg | 45.00 € | ||
| 10mg | 62.00 € | ||
| 25mg | 112.00 € | ||
| 50mg | 182.00 € | ||
| 100mg | 323.00 € | ||
| 200mg | 451.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
9-Phenanthrol
CAS:484-17-3
9-Phenanthrol is inhibitor of the transient receptor potential melastatin 4 (TRPM) channel, a Ca2+ -activated …
Formula:
C14H10O
Purity:
98.72%
Color and Shape:
Solid
Molecular weight:
194.23
Ref: TM-T22537
| 25mg | 48.00 € | ||
| 50mg | 57.00 € | ||
| 100mg | 82.00 € | ||
| 200mg | 107.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
TC-I2000
CAS:1159996-20-9
TC-I2000 is an TRPM8 channel blocker. Inhibits icilin-induced TRPM8 channel activation in rTRPM8-expressing CHO cells …
Formula:
C23H18F4N2O
Purity:
98.87%
Color and Shape:
Liquid
Molecular weight:
414.4
Ref: TM-T8449
| 5mg | 35.00 € | ||
| 10mg | 49.00 € | ||
| 25mg | 86.00 € | ||
| 50mg | 116.00 € | ||
| 100mg | 168.00 € | ||
| 200mg | 249.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
WS-12
CAS:68489-09-8
WS-12 is a potent TRPM8 agonist that acts as a cooling agent (EC50 : 193 …
Formula:
C18H27NO2
Purity:
99.99%
Color and Shape:
Whitish To White Solid Crystalline
Molecular weight:
289.41
Ref: TM-T7416
| 5mg | 48.00 € | ||
| 10mg | 65.00 € | ||
| 25mg | 99.00 € | ||
| 50mg | 128.00 € | ||
| 100mg | 166.00 € | ||
| 200mg | 239.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
Pyr10
CAS:1315323-00-2
Pyr10, a pyrazole derivative, selectively inhibits TRPC3, not STIM1/Orai1, with IC50 of 0.72 μM in …
Formula:
C18H13F6N3O2S
Purity:
99.69% - 99.70%
Color and Shape:
Solid
Molecular weight:
449.37
Ref: TM-T16686
| 5mg | 37.00 € | ||
| 10mg | 57.00 € | ||
| 25mg | 108.00 € | ||
| 50mg | 193.00 € | ||
| 100mg | 275.00 € | ||
| 1mL*10mM (DMSO) | 41.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
SN 2
CAS:823218-99-1
SN 2 is a novel and potent TRPML3 ion channel activator(EC50 = 1.13 μM). SN …
Formula:
C17H21NO
Purity:
99.20%
Color and Shape:
Solid
Molecular weight:
255.35
Ref: TM-T12941
| 5mg | 51.00 € | ||
| 10mg | 73.00 € | ||
| 25mg | 144.00 € | ||
| 50mg | 272.00 € | ||
| 100mg | 401.00 € | ||
| 200mg | 562.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
SB-705498
CAS:501951-42-4
SB705498 is a TRPV1 antagonist for hTRPV1. SB-705498 has been investigated for the treatment of …
Formula:
C17H16BrF3N4O
Purity:
98% - ≥95%
Color and Shape:
Solid
Molecular weight:
429.23
Ref: TM-T6660
| 5mg | 47.00 € | ||
| 10mg | 81.00 € | ||
| 25mg | 167.00 € | ||
| 50mg | 293.00 € | ||
| 100mg | 423.00 € | ||
| 200mg | 589.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
Vanilloid receptor antagonist 1
CAS:871814-52-7
Vanilloid receptor antagonist 1 (4-(7-Hydroxy-2-isopropyl-4-oxoquinazolin-3(4H)-yl)benzonitrile) is a potent vanilloid receptor TRPV1 antagonist.
Formula:
C18H15N3O2
Purity:
98.14%
Color and Shape:
Solid
Molecular weight:
305.33
Ref: TM-T9247
| 1mg | 95.00 € | ||
| 5mg | 226.00 € | ||
| 10mg | 341.00 € | ||
| 25mg | 579.00 € | ||
| 50mg | 816.00 € | ||
| 100mg | 1,161.00 € | ||
| 1mL*10mM (DMSO) | 45.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
AMG9810
CAS:545395-94-6
AMG 9810 blocks capsaicin's action on TRPV1; human IC50=24.5 nM, rat IC50=85.6 nM.
Formula:
C21H23NO3
Purity:
99.79% - 99.83%
Color and Shape:
Solid
Molecular weight:
337.41
Ref: TM-T7189
| 5mg | 50.00 € | ||
| 10mg | 60.00 € | ||
| 25mg | 115.00 € | ||
| 50mg | 201.00 € | ||
| 100mg | 353.00 € | ||
| 500mg | 820.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
Optovin
CAS:348575-88-2
Optovin is a TRPA1 activator, which is reversibly photoactivated.
Formula:
C15H13N3OS2
Purity:
100.00% - 99.16%
Color and Shape:
Solid
Molecular weight:
315.41
Ref: TM-T6617
| 2mg | 35.00 € | ||
| 5mg | 51.00 € | ||
| 10mg | 63.00 € | ||
| 25mg | 113.00 € | ||
| 50mg | 182.00 € | ||
| 100mg | 327.00 € | ||
| 200mg | 398.00 € | ||
| 1mL*10mM (DMSO) | 50.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
MDR-652
CAS:1933528-96-1
MDR-652 is a highly specific and efficacious agonist of nonpungent transient receptor potential vanilloid 1 …
Formula:
C22H23ClFN3O2S
Purity:
99.96%
Color and Shape:
Solid
Molecular weight:
447.95
Ref: TM-T22360
| 1mg | 45.00 € | ||
| 2mg | 62.00 € | ||
| 5mg | 93.00 € | ||
| 10mg | 140.00 € | ||
| 25mg | 244.00 € | ||
| 50mg | 359.00 € | ||
| 100mg | 524.00 € | ||
| 200mg | 709.00 € | ||
| 1mL*10mM (DMSO) | 101.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
TRPM8 antagonist WS-3
CAS:39711-79-0
TRPM8 antagonist WS-3 (Cyclohexanecarboxamide) is an agonist of TRPM8( EC50 : 3.7 μM).
Formula:
C13H25NO
Purity:
97.64%
Color and Shape:
Drypowder
Molecular weight:
211.34
Ref: TM-T5962
| 1g | 33.00 € | ||
| 1mL*10mM (DMSO) | 35.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
RN-1747
CAS:1024448-59-6
RN-1747: TRPV4 agonist (EC50: human 0.77 μM, mouse 4.0 μM, rat 4.1 μM), TRPM8 antagonist …
Formula:
C17H18ClN3O4S
Purity:
99.29%
Color and Shape:
Solid
Molecular weight:
395.86
Ref: TM-T16763
| 5mg | 43.00 € | ||
| 10mg | 72.00 € | ||
| 25mg | 122.00 € | ||
| 50mg | 182.00 € | ||
| 100mg | 305.00 € | ||
| 200mg | 435.00 € | ||
| 1mL*10mM (DMSO) | 45.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
ML329
CAS:19992-50-8
ML329 is a small molecule inhibitor of MITF, inhibiting TRPM-1 promoter activity.
Formula:
C16H12N2O4S
Purity:
99.07%
Color and Shape:
Solid
Molecular weight:
328.34
Ref: TM-T4028
| 1mg | 52.00 € | ||
| 2mg | 73.00 € | ||
| 5mg | 113.00 € | ||
| 10mg | 183.00 € | ||
| 25mg | 417.00 € | ||
| 50mg | 612.00 € | ||
| 100mg | 873.00 € | ||
| 1mL*10mM (DMSO) | 119.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
AMTB hydrochloride
CAS:926023-82-7
AMTB HCl: Novel TRPM8 blocker, relieves pain, treats urinary issues, moderates bladder reflexes in rats.
Formula:
C23H27ClN2O2S
Purity:
99.08%
Color and Shape:
Solid
Molecular weight:
430.99
Ref: TM-T19723
| 1mg | 37.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 123.00 € | ||
| 25mg | 260.00 € | ||
| 50mg | 438.00 € | ||
| 100mg | 647.00 € | ||
| 500mg | 1,366.00 € | ||
| 1mL*10mM (DMSO) | 89.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
TRPM8 antagonist 2
CAS:259674-19-6
TRPM8 antagonist 2 is a potent and selective TRPM8 antagonist with an IC50 of 0.2 …
Formula:
C26H26N2O2
Purity:
98.10%
Color and Shape:
Solid
Molecular weight:
398.5
Ref: TM-T5698
| 1mg | 40.00 € | ||
| 5mg | 83.00 € | ||
| 10mg | 122.00 € | ||
| 25mg | 203.00 € | ||
| 50mg | 319.00 € | ||
| 100mg | 530.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
