TRP/TRPV Channel
TRP (Transient Receptor Potential) channels, including the TRPV subfamily, are a group of ion channels involved in various sensory processes, such as temperature sensation, pain perception, and osmoregulation. TRP channels are widely expressed in different tissues and play a role in physiological responses to environmental stimuli. The TRPV channels, in particular, are involved in detecting temperature changes and are implicated in conditions such as chronic pain, inflammation, and cancer. At CymitQuimica, we offer a comprehensive range of TRP/TRPV channel modulators to support your research in sensory biology, pain management, and signal transduction.
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Pyr10
CAS:1315323-00-2
Pyr10, a pyrazole derivative, selectively inhibits TRPC3, not STIM1/Orai1, with IC50 of 0.72 μM in …
Formula:
C18H13F6N3O2S
Purity:
99.69% - 99.70%
Color and Shape:
Solid
Molecular weight:
449.37
Ref: TM-T16686
| 5mg | 37.00 € | ||
| 10mg | 57.00 € | ||
| 25mg | 108.00 € | ||
| 50mg | 193.00 € | ||
| 100mg | 275.00 € | ||
| 1mL*10mM (DMSO) | 41.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
SN 2
CAS:823218-99-1
SN 2 is a novel and potent TRPML3 ion channel activator(EC50 = 1.13 μM). SN …
Formula:
C17H21NO
Purity:
99.20%
Color and Shape:
Solid
Molecular weight:
255.35
Ref: TM-T12941
| 5mg | 51.00 € | ||
| 10mg | 73.00 € | ||
| 25mg | 144.00 € | ||
| 50mg | 272.00 € | ||
| 100mg | 401.00 € | ||
| 200mg | 562.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
SB-705498
CAS:501951-42-4
SB705498 is a TRPV1 antagonist for hTRPV1. SB-705498 has been investigated for the treatment of …
Formula:
C17H16BrF3N4O
Purity:
98% - ≥95%
Color and Shape:
Solid
Molecular weight:
429.23
Ref: TM-T6660
| 5mg | 47.00 € | ||
| 10mg | 81.00 € | ||
| 25mg | 167.00 € | ||
| 50mg | 293.00 € | ||
| 100mg | 423.00 € | ||
| 200mg | 589.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
N4-benzyl-N2-methylquinazoline-2,4-diamine hydrochloride
CAS:1135272-09-1
N4-benzyl-N2-methylquinazoline-2,4-diamine hydrochloride is an inhibitor of TRPC4.
Formula:
C16H17ClN4
Purity:
99.25%
Color and Shape:
Solid
Molecular weight:
300.79
Ref: TM-T8565
| 1mg | 131.00 € | ||
| 2mg | 185.00 € | ||
| 5mg | 282.00 € | ||
| 10mg | 430.00 € | ||
| 25mg | 709.00 € | ||
| 50mg | 996.00 € | ||
| 100mg | 1,347.00 € | ||
| 1mL*10mM (DMSO) | 282.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
MDR-652
CAS:1933528-96-1
MDR-652 is a highly specific and efficacious agonist of nonpungent transient receptor potential vanilloid 1 …
Formula:
C22H23ClFN3O2S
Purity:
99.96%
Color and Shape:
Solid
Molecular weight:
447.95
Ref: TM-T22360
| 1mg | 73.00 € | ||
| 2mg | 96.00 € | ||
| 5mg | 159.00 € | ||
| 10mg | 232.00 € | ||
| 25mg | 419.00 € | ||
| 50mg | 632.00 € | ||
| 100mg | 899.00 € | ||
| 1mL*10mM (DMSO) | 167.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
RN-1747
CAS:1024448-59-6
RN-1747: TRPV4 agonist (EC50: human 0.77 μM, mouse 4.0 μM, rat 4.1 μM), TRPM8 antagonist …
Formula:
C17H18ClN3O4S
Purity:
99.29%
Color and Shape:
Solid
Molecular weight:
395.86
Ref: TM-T16763
| 5mg | 43.00 € | ||
| 10mg | 72.00 € | ||
| 25mg | 122.00 € | ||
| 50mg | 182.00 € | ||
| 100mg | 305.00 € | ||
| 200mg | 435.00 € | ||
| 1mL*10mM (DMSO) | 45.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
ML-SI3
CAS:891016-02-7
CCG-143140 is a GLP-1 receptor inverse agonists.
Formula:
C23H31N3O3S
Purity:
99.75%
Color and Shape:
Solid
Molecular weight:
429.58
Ref: TM-T9226
| 2mg | 49.00 € | ||
| 5mg | 73.00 € | ||
| 10mg | 114.00 € | ||
| 25mg | 230.00 € | ||
| 50mg | 366.00 € | ||
| 100mg | 547.00 € | ||
| 1mL*10mM (DMSO) | 82.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Linoleoyl Ethanolamide
CAS:68171-52-8
Linoleoyl Ethanolamide is an endocannabinoid agent.
Formula:
C20H37NO2
Purity:
99.97%
Color and Shape:
Solid
Molecular weight:
323.51
Ref: TM-T8425
| 1mg | 36.00 € | ||
| 5mg | 68.00 € | ||
| 10mg | 90.00 € | ||
| 25mg | 162.00 € | ||
| 50mg | 236.00 € | ||
| 100mg | 343.00 € | ||
| 200mg | 515.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Fingolimod hydrochloride
CAS:162359-56-0
Fingolimod hydrochloride (FTY720) , a novel immune modulator, is a sphingosine 1-phosphate (S1P) antagonist (IC50: …
Formula:
C19H34ClNO2
Purity:
99.26% - 99.83%
Color and Shape:
White Solid
Molecular weight:
343.93
Ref: TM-T2539
| 50mg | 41.00 € | ||
| 100mg | 54.00 € | ||
| 200mg | 85.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Evifacotrep
CAS:2413739-88-3
Evifacotrep: TRPC5 antagonist for neurological disease research (WO2020061162, compound 100).
Formula:
C18H12ClF4N5O2
Purity:
98.6%
Color and Shape:
Solid
Molecular weight:
441.77
Ref: TM-T40042
| 1mg | 62.00 € | ||
| 2mg | 91.00 € | ||
| 5mg | 141.00 € | ||
| 10mg | 204.00 € | ||
| 25mg | 345.00 € | ||
| 50mg | 493.00 € | ||
| 100mg | 670.00 € | ||
| 200mg | 904.00 € | ||
| 1mL*10mM (DMSO) | 155.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
ML329
CAS:19992-50-8
ML329 is a small molecule inhibitor of MITF, inhibiting TRPM-1 promoter activity.
Formula:
C16H12N2O4S
Purity:
99.07%
Color and Shape:
Solid
Molecular weight:
328.34
Ref: TM-T4028
| 1mg | 52.00 € | ||
| 2mg | 73.00 € | ||
| 5mg | 113.00 € | ||
| 10mg | 183.00 € | ||
| 25mg | 417.00 € | ||
| 50mg | 612.00 € | ||
| 100mg | 873.00 € | ||
| 1mL*10mM (DMSO) | 119.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
AMTB hydrochloride
CAS:926023-82-7
AMTB HCl: Novel TRPM8 blocker, relieves pain, treats urinary issues, moderates bladder reflexes in rats.
Formula:
C23H27ClN2O2S
Purity:
99.08%
Color and Shape:
Solid
Molecular weight:
430.99
Ref: TM-T19723
| 1mg | 37.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 123.00 € | ||
| 25mg | 260.00 € | ||
| 50mg | 438.00 € | ||
| 100mg | 647.00 € | ||
| 500mg | 1,366.00 € | ||
| 1mL*10mM (DMSO) | 89.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
PF-4840154
CAS:1332708-14-1
PF-4840154: potent TrpA1 agonist; EC50 of 97 nM (rat) & 23 nM (human); triggers nociception …
Formula:
C26H38N6O2
Purity:
98.48%
Color and Shape:
Solid
Molecular weight:
466.62
Ref: TM-T4385
| 1mg | 107.00 € | ||
| 2mg | 154.00 € | ||
| 5mg | 320.00 € | ||
| 10mg | 462.00 € | ||
| 25mg | 737.00 € | ||
| 50mg | 1,050.00 € | ||
| 100mg | 1,417.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
HC067047 Hydrochloride(883031-03-6 free base)
CAS:1481646-76-7
HC-067047 hydrochloride, a TRPV4 antagonist, selectively inhibits human, rat, and mouse currents with IC50s: 486 …
Formula:
C26H29ClF3N3O2
Purity:
99.95%
Color and Shape:
Solid
Molecular weight:
507.98
Ref: TM-T4680L
| 1mg | 85.00 € | ||
| 5mg | 172.00 € | ||
| 10mg | 250.00 € | ||
| 25mg | 411.00 € | ||
| 50mg | 577.00 € | ||
| 100mg | 781.00 € | ||
| 200mg | 1,035.00 € | ||
| 1mL*10mM (DMSO) | 210.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
HC-030031
CAS:349085-38-7
HC-030031 (TOSLAB 829227) is a potent TRPA1 inhibitor, which antagonizes AITC- and formalin-evoked calcium influx …
Formula:
C18H21N5O3
Purity:
99.69% - ≥95%
Color and Shape:
Solid
Molecular weight:
355.39
Ref: TM-T6530
| 10mg | 50.00 € | ||
| 50mg | 94.00 € | ||
| 100mg | 143.00 € | ||
| 200mg | 182.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
TRPM8 antagonist 2
CAS:259674-19-6
TRPM8 antagonist 2 is a potent and selective TRPM8 antagonist with an IC50 of 0.2 …
Formula:
C26H26N2O2
Purity:
98.10%
Color and Shape:
Solid
Molecular weight:
398.5
Ref: TM-T5698
| 1mg | 36.00 € | ||
| 5mg | 70.00 € | ||
| 10mg | 103.00 € | ||
| 25mg | 168.00 € | ||
| 50mg | 271.00 € | ||
| 100mg | 435.00 € | ||
| 200mg | 625.00 € | ||
| 1mL*10mM (DMSO) | 77.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
GSK2193874
CAS:1336960-13-4
GSK2193874 was identified as a selective, orally active TRPV4 blocker.
Formula:
C37H38BrF3N4O
Purity:
98.79% - ≥95%
Color and Shape:
Solid
Molecular weight:
691.62
Ref: TM-T5640
| 1mg | 43.00 € | ||
| 2mg | 61.00 € | ||
| 5mg | 85.00 € | ||
| 10mg | 129.00 € | ||
| 25mg | 247.00 € | ||
| 50mg | 403.00 € | ||
| 100mg | 593.00 € | ||
| 1mL*10mM (DMSO) | 111.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
ML204
CAS:5465-86-1
ML204 is a novel potent antagonist that selectively modulates native TRPC4/C5 ion channels.
Formula:
C15H18N2
Purity:
98.1% - 99.98%
Color and Shape:
Solid
Molecular weight:
226.32
Ref: TM-T2298
| 2mg | 35.00 € | ||
| 5mg | 51.00 € | ||
| 10mg | 73.00 € | ||
| 25mg | 110.00 € | ||
| 50mg | 143.00 € | ||
| 100mg | 216.00 € | ||
| 200mg | 277.00 € | ||
| 500mg | 458.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
RN-1734
CAS:946387-07-1
RN-1734 is selective TRPV4 channel antagonist(IC50 of 2.3 μM,5.9 μM,3.2 μM for hTRPV4, mTRPV4 and …
Formula:
C14H22Cl2N2O2S
Purity:
99.1% - 99.30%
Color and Shape:
Solid
Molecular weight:
353.31
Ref: TM-T7572
| 10mg | 47.00 € | ||
| 25mg | 88.00 € | ||
| 50mg | 125.00 € | ||
| 100mg | 188.00 € | ||
| 200mg | 271.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
AMG 333
CAS:1416799-28-4
AMG 333 is TRPM8 antagonist with an IC50 of 13 nM,a Clinical Candidate for the …
Formula:
C20H12F5N3O4
Purity:
99.95%
Color and Shape:
Solid
Molecular weight:
453.32
Ref: TM-T5479
| 1mg | 36.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 125.00 € | ||
| 25mg | 241.00 € | ||
| 50mg | 388.00 € | ||
| 100mg | 554.00 € | ||
| 1mL*10mM (DMSO) | 86.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
