TRP/TRPV Channel
TRP (Transient Receptor Potential) channels, including the TRPV subfamily, are a group of ion channels involved in various sensory processes, such as temperature sensation, pain perception, and osmoregulation. TRP channels are widely expressed in different tissues and play a role in physiological responses to environmental stimuli. The TRPV channels, in particular, are involved in detecting temperature changes and are implicated in conditions such as chronic pain, inflammation, and cancer. At CymitQuimica, we offer a comprehensive range of TRP/TRPV channel modulators to support your research in sensory biology, pain management, and signal transduction.
Found 98 products for "TRP/TRPV Channel".
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
AM-0902
CAS:AM-0902 is a potent and specific TRPA1 antagonist (IC50s: 71/131 nM for rTRPA1 and hTRPA1).Formula:C17H15ClN6O2Purity:>99.99%Color and Shape:White SolidMolecular weight:370.79SB 452533
CAS:SB 452533 is an antagonist of the vanilloid receptor 1(pKb: 7.8).Formula:C18H22BrN3OPurity:99.87%Color and Shape:SolidMolecular weight:376.29Ref: TM-T23322
2mg39.00€5mg60.00€1mL*10mM (DMSO)73.00€10mg92.00€25mg173.00€50mg269.00€100mg389.00€200mg555.00€Pico145
CAS:Pico145 (HC-608) is a remarkable inhibitor of TRPC1/4/5 channels.Formula:C23H20ClF3N4O5Purity:99.06%Color and Shape:SolidMolecular weight:524.88Ref: TM-T16532
1mg70.00€5mg150.00€1mL*10mM (DMSO)167.00€10mg215.00€25mg358.00€50mg517.00€100mg707.00€200mg1,009.00€TRPM4-IN-1
CAS:TRPM4-IN-1 (4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid) is a potent and selective inhibitor of TRPM4 with an IC50 of 1.5 μM.Formula:C15H11Cl2NO4Purity:97.22%Color and Shape:SolidMolecular weight:340.16MK6-83
CAS:MK6-83 is the transient receptor potential channel ML3 agonist.Formula:C16H20N2O2S2Purity:99.5%Color and Shape:White SolidMolecular weight:336.47Ref: TM-T24477
10mgTo inquire25mgTo inquire50mgTo inquire100mgTo inquire5mg46.00€1mL*10mM (DMSO)49.00€9-Phenanthrol
CAS:9-Phenanthrol is inhibitor of the transient receptor potential melastatin 4 (TRPM) channel, a Ca2+ -activated non-selective cation channel.Formula:C14H10OPurity:98.48%Color and Shape:Yellow SolidMolecular weight:194.23TC-I2000
CAS:TC-I2000 is an TRPM8 channel blocker. Inhibits icilin-induced TRPM8 channel activation in rTRPM8-expressing CHO cells with IC50 of 53 nM.Formula:C23H18F4N2OPurity:99.77%Color and Shape:White SolidMolecular weight:414.4ML204 hydrochloride
CAS:ML204 hydrochloride (ML204 HCl) is a TRPC4/TRPC5 channel antagonist.Formula:C15H19ClN2Color and Shape:Yellow SolidMolecular weight:262.78WS-12
CAS:WS-12 is a potent TRPM8 agonist that acts as a cooling agent (EC50 : 193 nM)Formula:C18H27NO2Purity:99.99%Color and Shape:White SolidMolecular weight:289.41Pyr10
CAS:Pyr10, a pyrazole derivative, selectively inhibits TRPC3, not STIM1/Orai1, with IC50 of 0.72 μM in TRPC3-HEK293, and 13.08 μM in BRL-2H3 cells.Formula:C18H13F6N3O2SPurity:99.69% - 99.7%Color and Shape:SolidMolecular weight:449.37SB-705498
CAS:SB705498 is a TRPV1 antagonist for hTRPV1. SB-705498 has been investigated for the treatment of Rhinitis, Chronic Cough, and Non-allergic Rhinitis.Formula:C17H16BrF3N4OPurity:99.57% - ≥95%Color and Shape:SolidMolecular weight:429.23Vanilloid receptor antagonist 1
CAS:Vanilloid receptor antagonist 1 (4-(7-Hydroxy-2-isopropyl-4-oxoquinazolin-3(4H)-yl)benzonitrile) is a potent vanilloid receptor TRPV1 antagonist.Formula:C18H15N3O2Purity:98.14%Color and Shape:White SolidMolecular weight:305.33AMG9810
CAS:AMG 9810 blocks capsaicin's action on TRPV1; human IC50=24.5 nM, rat IC50=85.6 nM.Formula:C21H23NO3Purity:99.79% - 99.95%Color and Shape:SolidMolecular weight:337.41Ref: TM-T7189
2mg34.00€5mg48.00€1mL*10mM (DMSO)50.00€10mg58.00€25mg110.00€50mg177.00€100mg286.00€200mg425.00€Optovin
CAS:Optovin is a TRPA1 activator, which is reversibly photoactivated.Formula:C15H13N3OS2Purity:99.22% - 99.47%Color and Shape:SolidMolecular weight:315.41Ref: TM-T6617
2mg37.00€5mg54.00€1mL*10mM (DMSO)60.00€10mg88.00€25mg152.00€50mg236.00€100mg385.00€200mg560.00€MDR-652
CAS:MDR-652 is a highly specific and efficacious agonist of nonpungent transient receptor potential vanilloid 1 (TRPV1) with Ki value of 11.4 nM and 23.8 nM forFormula:C22H23ClFN3O2SPurity:99.96%Color and Shape:SolidMolecular weight:447.95Ref: TM-T22360
1mg60.00€2mg87.00€5mg130.00€1mL*10mM (DMSO)142.00€10mg178.00€25mg331.00€50mg512.00€100mg707.00€200mg973.00€RN-1747
CAS:RN-1747: TRPV4 agonist (EC50: human 0.77 μM, mouse 4.0 μM, rat 4.1 μM), TRPM8 antagonist (IC50: 4 μM).Formula:C17H18ClN3O4SPurity:99.29%Color and Shape:SolidMolecular weight:395.86AMTB hydrochloride
CAS:AMTB HCl: Novel TRPM8 blocker, relieves pain, treats urinary issues, moderates bladder reflexes in rats.Formula:C23H27ClN2O2SPurity:99.08%Color and Shape:White SolidMolecular weight:430.99Ref: TM-T19723
1mg34.00€5mg74.00€1mL*10mM (DMSO)87.00€10mg119.00€25mg250.00€50mg424.00€100mg627.00€200mg890.00€TRPM8 antagonist 2
CAS:TRPM8 antagonist 2 is a potent and selective TRPM8 antagonist with an IC50 of 0.2 nM. TRPM8 antagonist 2 is used in the research of neuropathic pain syndromes.Formula:C26H26N2O2Purity:98.1%Color and Shape:White SolidMolecular weight:398.5Ref: TM-T5698
1mg34.00€5mg66.00€1mL*10mM (DMSO)73.00€10mg99.00€25mg167.00€50mg260.00€100mg416.00€200mg600.00€AC1903
CAS:AC1903 is a specific inhibitor of TRPC5 channel, and has been shown to suppress severe proteinuria and prevent podocyte loss.Formula:C19H17N3OPurity:98.45%Color and Shape:White SolidMolecular weight:303.36ASP7663
CAS:ASP7663 is a TRPA1 Receptor Agonist and exhibiting an abdominal analgesic effect in vivo.Formula:C14H14FNO3Purity:98.61%Color and Shape:SolidMolecular weight:263.26
