TRP/TRPV Channel
TRP (Transient Receptor Potential) channels, including the TRPV subfamily, are a group of ion channels involved in various sensory processes, such as temperature sensation, pain perception, and osmoregulation. TRP channels are widely expressed in different tissues and play a role in physiological responses to environmental stimuli. The TRPV channels, in particular, are involved in detecting temperature changes and are implicated in conditions such as chronic pain, inflammation, and cancer. At CymitQuimica, we offer a comprehensive range of TRP/TRPV channel modulators to support your research in sensory biology, pain management, and signal transduction.
Found 98 products for "TRP/TRPV Channel".
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cim0216
CAS:CIM0216 is a synthetic TRPM3 activator whose potency and apparent affinity greatly exceeds that of the canonical TRPM3 agonist.Formula:C21H21N3O2Purity:99.87%Color and Shape:SolidMolecular weight:347.41Ref: TM-T9263
1mg44.00€2mg56.00€5mg87.00€1mL*10mM (DMSO)96.00€10mg138.00€25mg281.00€50mg442.00€100mg665.00€500mg1,378.00€AMG 517
CAS:AMG 517 is an effective and specific TRPV1 antagonist, antagonizes proton (IC50: 0.76 nM), capsaicin (IC50: 0.62 nM) and heat activation (IC50: 1.3 nM) of TRPV1Formula:C20H13F3N4O2SPurity:99.77% - 99.85%Color and Shape:SolidMolecular weight:430.4JNJ-28583113
CAS:JNJ-28583113 is a TRPM2 antagonist, inducing phosphorylation of GSK3α and β subunits, protecting cells from oxidative stress-induced cell death.Formula:C19H21F3N2O2Purity:98.57%Color and Shape:White SolidMolecular weight:366.38Ref: TM-T74779
1mg87.00€5mg178.00€1mL*10mM (DMSO)197.00€10mg222.00€25mg358.00€50mg555.00€100mg707.00€200mg982.00€SAR7334
CAS:SAR7334 (TRCP6-IN-1) is a potent and specific inhibitor of TRPC6(IC50 of 7.9 nM).Formula:C21H22ClN3OPurity:99.71% - 99.72%Color and Shape:SolidMolecular weight:367.87Ref: TM-T12849
1mg67.00€2mg88.00€5mg152.00€1mL*10mM (DMSO)166.00€10mg236.00€25mg295.00€50mg349.00€100mg439.00€200mg628.00€OptoBI-1
CAS:OptoBI-1 is a photochromic, TRPC3/6/7-selective agonist based on a benzimidazole structure.Formula:C32H37N5O2Color and Shape:Yellow SolidMolecular weight:523.67JYL 1421
CAS:JYL 1421 (SC 0030) is an antagonist of TRPV1 receptor (IC50 = 8 nM).Formula:C20H26FN3O2S2Purity:98.83%Color and Shape:SolidMolecular weight:423.57Ref: TM-T15634
1mg43.00€1mL*10mM (DMSO)103.00€5mg110.00€10mg173.00€25mg349.00€50mg532.00€100mg847.00€TRPC6-PAM-C20
CAS:TRPC6-PAM-C20, a selective enhancer for TRPC6, boosts calcium in HEK cells and OAG-related platelet clumping, EC50: 2.37μM.Formula:C22H21NO4Purity:98.16% - 99.65%Color and Shape:White SolidMolecular weight:363.41D-3263 hydrochloride
CAS:D-3263 hydrochloride (D3263 HCl salt) is enteric-coated, orally bioavailable transient receptor potential melatonin member 8 (TRPM8) agonist.Formula:C21H32ClN3O3Purity:99.93%Color and Shape:SolidMolecular weight:409.95RN9893
CAS:RN9893 is a selective and potent TRPV4 receptor antagonist with IC50 values of 320, 420 and 660 nM for TRPV4 receptors in mouse, human and rat, respectively.Formula:C21H23F3N4O5SPurity:99.99%Color and Shape:White SolidMolecular weight:500.49Asivatrep
CAS:Asivatrep (PAC14028) is a selective and potent antagonist of transient receptor potential vanilloid subtype 1 (TRPV1) for the study of atopic dermatitis.Formula:C21H22F5N3O3SPurity:95.13%Color and Shape:SolidMolecular weight:491.48AM12
CAS:AM12 inhibits Lanthanide-evoked TRPC5 activity (IC50: 0.28 μM).Formula:C15H9BrO5Purity:98%Color and Shape:SolidMolecular weight:349.13GSK1702934A
CAS:GSK1702934A is a TRPC3 agonist with pro-arrhythmic and positive inotropic effects and is used in the study of diabetes mellitus.Formula:C22H25N3O2SPurity:98.15%Color and Shape:SolidMolecular weight:395.52N-Oleoyl Valine
CAS:N-Oleoyl valine, an N-acyl amine, antagonizes TRPV3 for thermoregulation; rises post-cold exposure; elevates in mouse lung injury.Formula:C23H43NO3Color and Shape:SolidMolecular weight:381.59TRPV4 agonist-1
CAS:TRPV4 agonist-1 is an agonist of TRPV4 (EC50: 60 nM in the hTRPV4 Ca2+ assay).Formula:C25H23ClF2N4O2Purity:98%Color and Shape:SolidMolecular weight:484.93TRPM4-IN-2
CAS:NBA, or TRPM4-IN-2, is a potent TRPM4 inhibitor with IC50 of 0.16 μM, used in prostate and colorectal cancer research.Formula:C19H14ClNO4Purity:99.21%Color and Shape:White SolidMolecular weight:355.77TRPV3 antagonist 74a
CAS:TRPV3 antagonist 74a (TRPV3 74a) is a specific TRPV3 antagonist for the study of neurological disorders.Formula:C17H17F3N2O2Purity:≥98.0%Color and Shape:White SolidMolecular weight:338.32SET 2
CAS:SET 2 is an antagonist of transient receptor potential vanilloid type 2(TRPV2) with an IC50 of 0.46 μM. SET 2 shows selectivity over TRPV1, TRPV3 and TRPV4.Formula:C17H21F3N4O2SPurity:99.77%Color and Shape:SolidMolecular weight:402.43Ref: TM-T37097
500mgTo inquire5mg55.00€1mL*10mM (DMSO)67.00€10mg92.00€25mg168.00€50mg284.00€100mg414.00€FEMA-4809
CAS:FEMA-4809 activates TRPM8, the ion channel for cold sensation, and is used as a cooling agent.Formula:C17H17N3O2SPurity:99.9%Color and Shape:SolidMolecular weight:327.4Ref: TM-T27308
1mg34.00€5mg73.00€1mL*10mM (DMSO)84.00€10mg110.00€25mg180.00€50mg255.00€100mg363.00€200mg497.00€Elismetrep
CAS:Elismetrep (MT-8554) is an orally available TRPM8 inhibitor with potential analgesic activity for the study of vasomotor symptoms in postmenopausal women.Formula:C27H21F3N2O5SPurity:99.37% - 99.93%Color and Shape:White SolidMolecular weight:542.53Ref: TM-T27253
1mg101.00€5mg241.00€1mL*10mM (DMSO)286.00€10mg385.00€25mg703.00€50mg888.00€100mg1,189.00€Mavatrep
CAS:Mavatrep (JNJ-39439335) is a selective antagonist of TRPV1 with Ki of 6.5 nM and can be used for studies about inflammatory pain.Formula:C25H21F3N2OPurity:98.51% - 99.31%Color and Shape:Yellow SolidMolecular weight:422.44Ref: TM-T16014
1mg63.00€2mg90.00€5mg137.00€1mL*10mM (DMSO)150.00€10mg215.00€25mg385.00€50mg618.00€100mg888.00€200mg1,243.00€
