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TRP/TRPV Channel

TRP/TRPV Channel

TRP (Transient Receptor Potential) channels, including the TRPV subfamily, are a group of ion channels involved in various sensory processes, such as temperature sensation, pain perception, and osmoregulation. TRP channels are widely expressed in different tissues and play a role in physiological responses to environmental stimuli. The TRPV channels, in particular, are involved in detecting temperature changes and are implicated in conditions such as chronic pain, inflammation, and cancer. At CymitQuimica, we offer a comprehensive range of TRP/TRPV channel modulators to support your research in sensory biology, pain management, and signal transduction.

Found 92 products of "TRP/TRPV Channel"

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  • SAR7334
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    SAR7334

    CAS:
    <p>SAR7334 (TRCP6-IN-1) is a potent and specific inhibitor of TRPC6(IC50 of 7.9 nM).</p>
    Formula:C21H22ClN3O
    Purity:99.62% - 99.71%
    Color and Shape:Solid
    Molecular weight:367.87

    Ref: TM-T12849

  • JYL 1421
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    JYL 1421

    CAS:
    <p>JYL 1421 (SC 0030) is an antagonist of TRPV1 receptor (IC50 = 8 nM).</p>
    Formula:C20H26FN3O2S2
    Purity:98.83%
    Color and Shape:Solid
    Molecular weight:423.57

    Ref: TM-T15634

  • TRPC6-PAM-C20
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    TRPC6-PAM-C20

    CAS:
    <p>TRPC6-PAM-C20, a selective enhancer for TRPC6, boosts calcium in HEK cells and OAG-related platelet clumping, EC50: 2.37μM.</p>
    Formula:C22H21NO4
    Purity:98.16%
    Color and Shape:Solid
    Molecular weight:363.41

    Ref: TM-T37428

  • AM12
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    AM12

    CAS:
    <p>AM12 inhibits Lanthanide-evoked TRPC5 activity (IC50: 0.28 μM).</p>
    Formula:C15H9BrO5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:349.13

    Ref: TM-T13546

  • D-3263 hydrochloride
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    D-3263 hydrochloride

    CAS:
    <p>D-3263 hydrochloride (D3263 HCl salt) is enteric-coated, orally bioavailable transient receptor potential melatonin member 8 (TRPM8) agonist.</p>
    Formula:C21H32ClN3O3
    Purity:99.93%
    Color and Shape:Solid
    Molecular weight:409.95

    Ref: TM-T10929L

  • TRPM4-IN-2
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    TRPM4-IN-2

    CAS:
    <p>NBA, or TRPM4-IN-2, is a potent TRPM4 inhibitor with IC50 of 0.16 μM, used in prostate and colorectal cancer research.</p>
    Formula:C19H14ClNO4
    Purity:99.21%
    Color and Shape:Solid
    Molecular weight:355.77

    Ref: TM-T61275

  • Asivatrep
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    Asivatrep

    CAS:
    <p>Asivatrep (PAC14028) is a selective and potent antagonist of transient receptor potential vanilloid subtype 1 (TRPV1) for the study of atopic dermatitis.</p>
    Formula:C21H22F5N3O3S
    Purity:95.13%
    Color and Shape:Solid
    Molecular weight:491.48

    Ref: TM-T16426

  • TRPV3 antagonist 74a
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    TRPV3 antagonist 74a

    CAS:
    <p>TRPV3 antagonist 74a (TRPV3 74a) is a specific TRPV3 antagonist for the study of neurological disorders.</p>
    Formula:C17H17F3N2O2
    Purity:≥98.0%
    Color and Shape:Solid
    Molecular weight:338.32

    Ref: TM-T37429

  • RN9893
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    RN9893

    CAS:
    <p>RN9893 is a selective and potent TRPV4 receptor antagonist with IC50 values of 320, 420 and 660 nM for TRPV4 receptors in mouse, human and rat, respectively.</p>
    Formula:C21H23F3N4O5S
    Purity:99.89%
    Color and Shape:Solid
    Molecular weight:500.49

    Ref: TM-T28548

  • TRPV4 agonist-1
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    TRPV4 agonist-1

    CAS:
    <p>TRPV4 agonist-1 is an agonist of TRPV4 (EC50: 60 nM in the hTRPV4 Ca2+ assay).</p>
    Formula:C25H23ClF2N4O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:484.93

    Ref: TM-T13214

  • Motugivatrep
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    Motugivatrep

    CAS:
    <p>Motugivatrep is a potent and selective TRPV1 antagonist that can be used to study TRPV1-related respiratory diseases.</p>
    Formula:C22H20F3NO3
    Purity:99.22%
    Color and Shape:Solid
    Molecular weight:403.39

    Ref: TM-T64312

  • GSK1702934A
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    GSK1702934A

    CAS:
    <p>GSK1702934A is a TRPC3 agonist with pro-arrhythmic and positive inotropic effects and is used in the study of diabetes mellitus.</p>
    Formula:C22H25N3O2S
    Purity:98.15%
    Color and Shape:Solid
    Molecular weight:395.52

    Ref: TM-T15425

  • ABT 102
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    ABT 102

    CAS:
    <p>ABT 102 (CHEMBL398338) is a selective antagonist of transient receptor potential vanilloid 1 (TRPV1) receptor.</p>
    Formula:C21H24N4O
    Purity:98.38% - 99.86%
    Color and Shape:Solid
    Molecular weight:348.44

    Ref: TM-T29522

  • Mavatrep
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    Mavatrep

    CAS:
    <p>Mavatrep (JNJ-39439335) is a selective antagonist of TRPV1 with Ki of 6.5 nM and can be used for studies about inflammatory pain.</p>
    Formula:C25H21F3N2O
    Purity:98.51% - 99.31%
    Color and Shape:Solid
    Molecular weight:422.44

    Ref: TM-T16014

  • SET 2
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    SET 2

    CAS:
    <p>SET 2 is an antagonist of transient receptor potential vanilloid type 2(TRPV2) with an IC50 of 0.46 μM. SET 2 shows selectivity over TRPV1, TRPV3 and TRPV4.</p>
    Formula:C17H21F3N4O2S
    Purity:99.77%
    Color and Shape:Solid
    Molecular weight:402.43

    Ref: TM-T37097

  • Elismetrep
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    Elismetrep

    CAS:
    <p>Elismetrep (MT-8554) is an orally available TRPM8 inhibitor with potential analgesic activity for the study of vasomotor symptoms in postmenopausal women.</p>
    Formula:C27H21F3N2O5S
    Purity:99.37% - 99.93%
    Color and Shape:Solid
    Molecular weight:542.53

    Ref: TM-T27253

  • MSP3
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    MSP3

    CAS:
    <p>MSP3 is an agonist of TRPV1 (EC50 = 0.87 μM) and shows antinociceptive and neuroprotective effects.</p>
    Formula:C16H19NO3S
    Purity:99.89%
    Color and Shape:Solid
    Molecular weight:305.39

    Ref: TM-T28118

  • HC-070
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    HC-070

    CAS:
    <p>HC-070 is a TRPC5 and TRPC4 antagonist (IC50 = 9.3 nM and 46 nM).</p>
    Formula:C22H20Cl2N4O4
    Purity:98.48%
    Color and Shape:Solid
    Molecular weight:475.32

    Ref: TM-T15465

  • Pyr3
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    Pyr3

    CAS:
    <p>Pyr3 selectively blocks TRPC3 channels, reducing Ca2+ influx; it's effective at 700 nM.</p>
    Formula:C16H11Cl3F3N3O3
    Purity:98.04%
    Color and Shape:Solid
    Molecular weight:456.63

    Ref: TM-T16687

  • TC-I 2014
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    TC-I 2014

    CAS:
    <p>TC-I 2014 shows antiallodynic properties in pain models.</p>
    Formula:C23H19F6N3O
    Purity:99.07%
    Color and Shape:Solid
    Molecular weight:467.41

    Ref: TM-T17006