TRP/TRPV Channel
TRP (Transient Receptor Potential) channels, including the TRPV subfamily, are a group of ion channels involved in various sensory processes, such as temperature sensation, pain perception, and osmoregulation. TRP channels are widely expressed in different tissues and play a role in physiological responses to environmental stimuli. The TRPV channels, in particular, are involved in detecting temperature changes and are implicated in conditions such as chronic pain, inflammation, and cancer. At CymitQuimica, we offer a comprehensive range of TRP/TRPV channel modulators to support your research in sensory biology, pain management, and signal transduction.
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cim0216
CAS:1031496-06-6
CIM0216 is a synthetic TRPM3 activator whose potency and apparent affinity greatly exceeds that of …
Formula:
C21H21N3O2
Purity:
99.87%
Color and Shape:
Solid
Molecular weight:
347.41
Ref: TM-T9263
| 1mg | 46.00 € | ||
| 2mg | 60.00 € | ||
| 5mg | 92.00 € | ||
| 10mg | 146.00 € | ||
| 25mg | 297.00 € | ||
| 50mg | 465.00 € | ||
| 100mg | 700.00 € | ||
| 500mg | 1,420.00 € | ||
| 1mL*10mM (DMSO) | 92.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
JNJ-17203212
CAS:821768-06-3
JNJ-17203212 is a potent and selective antagonist of TRPV1 (human TRPV1 and rat TRPV1, IC50 …
Formula:
C17H15F6N5O
Purity:
99.94%
Color and Shape:
Solid
Molecular weight:
419.32
Ref: TM-T7526
| 2mg | 39.00 € | ||
| 5mg | 57.00 € | ||
| 10mg | 91.00 € | ||
| 25mg | 133.00 € | ||
| 50mg | 184.00 € | ||
| 100mg | 278.00 € | ||
| 1mL*10mM (DMSO) | 62.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Chembridge-5861528
CAS:332117-28-9
Chembridge-5861528 (TCS 5861528) is a TRPA1 channel blocker that antagonizes AITC- and 4-HNE-evoked calcium influx …
Formula:
C19H23N5O3
Purity:
100%
Color and Shape:
Solid
Molecular weight:
369.42
Ref: TM-T2711
| 5mg | 40.00 € | ||
| 10mg | 59.00 € | ||
| 25mg | 107.00 € | ||
| 50mg | 168.00 € | ||
| 100mg | 253.00 € | ||
| 200mg | 362.00 € | ||
| 1mL*10mM (DMSO) | 44.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
TRPM8 antagonist WS-3
CAS:39711-79-0
TRPM8 antagonist WS-3 (Cyclohexanecarboxamide) is an agonist of TRPM8( EC50 : 3.7 μM).
Formula:
C13H25NO
Purity:
97.64%
Color and Shape:
Drypowder
Molecular weight:
211.34
Ref: TM-T5962
| 1g | 33.00 € | ||
| 1mL*10mM (DMSO) | 35.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Vanilloid receptor antagonist 1
CAS:871814-52-7
Vanilloid receptor antagonist 1 (4-(7-Hydroxy-2-isopropyl-4-oxoquinazolin-3(4H)-yl)benzonitrile) is a potent vanilloid receptor TRPV1 antagonist.
Formula:
C18H15N3O2
Purity:
98.14%
Color and Shape:
Solid
Molecular weight:
305.33
Ref: TM-T9247
| 1mg | 95.00 € | ||
| 5mg | 226.00 € | ||
| 10mg | 341.00 € | ||
| 25mg | 579.00 € | ||
| 50mg | 816.00 € | ||
| 100mg | 1,161.00 € | ||
| 1mL*10mM (DMSO) | 45.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
AMG9810
CAS:545395-94-6
AMG 9810 blocks capsaicin's action on TRPV1; human IC50=24.5 nM, rat IC50=85.6 nM.
Formula:
C21H23NO3
Purity:
99.79% - 99.83%
Color and Shape:
Solid
Molecular weight:
337.41
Ref: TM-T7189
| 5mg | 50.00 € | ||
| 10mg | 60.00 € | ||
| 25mg | 115.00 € | ||
| 50mg | 201.00 € | ||
| 100mg | 353.00 € | ||
| 500mg | 820.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Optovin
CAS:348575-88-2
Optovin is a TRPA1 activator, which is reversibly photoactivated.
Formula:
C15H13N3OS2
Purity:
100.00% - 99.16%
Color and Shape:
Solid
Molecular weight:
315.41
Ref: TM-T6617
| 1mg | 40.00 € | ||
| 2mg | 51.00 € | ||
| 5mg | 81.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 186.00 € | ||
| 50mg | 310.00 € | ||
| 100mg | 557.00 € | ||
| 200mg | 678.00 € | ||
| 1mL*10mM (DMSO) | 85.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
SAR7334
CAS:1333210-07-3
SAR7334 (TRCP6-IN-1) is a potent and specific inhibitor of TRPC6(IC50 of 7.9 nM).
Formula:
C21H22ClN3O
Purity:
99.62%
Color and Shape:
Solid
Molecular weight:
367.87
Ref: TM-T12849
| 1mg | 70.00 € | ||
| 5mg | 157.00 € | ||
| 10mg | 245.00 € | ||
| 25mg | 395.00 € | ||
| 50mg | 558.00 € | ||
| 100mg | 694.00 € | ||
| 1mL*10mM (DMSO) | 168.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
TRPV3 antagonist 74a
CAS:1432051-63-2
TRPV3 antagonist 74a (TRPV3 74a) is a specific TRPV3 antagonist for the study of neurological …
Formula:
C17H17F3N2O2
Purity:
≥98.0%
Color and Shape:
Solid
Molecular weight:
338.32
Ref: TM-T37429
| 1mg | 474.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
Pyr3
CAS:1160514-60-2
Pyr3 selectively blocks TRPC3 channels, reducing Ca2+ influx; it's effective at 700 nM.
Formula:
C16H11Cl3F3N3O3
Purity:
99.47%
Color and Shape:
Solid
Molecular weight:
456.63
Ref: TM-T16687
| 1mg | 35.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 76.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 212.00 € | ||
| 50mg | 359.00 € | ||
| 100mg | 505.00 € | ||
| 200mg | 729.00 € | ||
| 500mg | 1,096.00 € | ||
| 1mL*10mM (DMSO) | 85.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
Olvanil
CAS:58493-49-5
Olvanil (N-Vannilyloleoylamide) is a vanilloid receptor agonist with EC50 of 0.7nM.
Formula:
C26H43NO3
Purity:
95.06%
Color and Shape:
Solid
Molecular weight:
417.62
Ref: TM-T23106
| 1mg | 49.00 € | ||
| 2mg | 72.00 € | ||
| 5mg | 107.00 € | ||
| 10mg | 159.00 € | ||
| 25mg | 261.00 € | ||
| 50mg | 364.00 € | ||
| 100mg | 521.00 € | ||
| 200mg | 703.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
EIPA hydrochloride
CAS:1345839-28-2
EIPA hydrochloride also inhibits Na+/H+-exchanger (NHE) and macropinocytosisEIPA hydrochloride (L593754 hydrochloride) is a TRPP3 channel …
Formula:
C11H19Cl2N7O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
336.22
Ref: TM-T11172
| 50mg | To inquire | ||
| 100mg | To inquire |
Estimated delivery in United States, on Wednesday 22 Jan 2025
SET 2
CAS:2313525-20-9
SET 2 is an antagonist of transient receptor potential vanilloid type 2(TRPV2) with an IC50 …
Formula:
C17H21F3N4O2S
Purity:
98.43%
Color and Shape:
Liquid
Molecular weight:
402.43
Ref: TM-T37097
| 5mg | 57.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 174.00 € | ||
| 50mg | 294.00 € | ||
| 100mg | 429.00 € | ||
| 500mg | To inquire | ||
| 1mL*10mM (DMSO) | 71.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
ABT 102
CAS:808756-71-0
ABT 102 (CHEMBL398338) is a selective antagonist of transient receptor potential vanilloid 1 (TRPV1) receptor.
Formula:
C21H24N4O
Purity:
98.38% - 99.72%
Color and Shape:
Solid
Molecular weight:
348.44
Ref: TM-T29522
| 1mg | 112.00 € | ||
| 5mg | 242.00 € | ||
| 10mg | 359.00 € | ||
| 25mg | 547.00 € | ||
| 50mg | 765.00 € | ||
| 100mg | 1,026.00 € | ||
| 200mg | 1,367.00 € | ||
| 1mL*10mM (DMSO) | 252.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
FEMA-4809
CAS:1374760-95-8
FEMA-4809 activates TRPM8, the ion channel for cold sensation, and is used as a cooling …
Formula:
C17H17N3O2S
Purity:
99.19%
Color and Shape:
Solid
Molecular weight:
327.4
Ref: TM-T27308
| 1mg | 53.00 € | ||
| 5mg | 114.00 € | ||
| 10mg | 183.00 € | ||
| 25mg | 311.00 € | ||
| 50mg | 440.00 € | ||
| 100mg | 626.00 € | ||
| 500mg | 1,238.00 € | ||
| 1mL*10mM (DMSO) | 132.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
AM12
CAS:2387510-84-9
AM12 inhibits Lanthanide-evoked TRPC5 activity (IC50: 0.28 μM).
Formula:
C15H9BrO5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
349.13
Ref: TM-T13546
| 10mg | 448.00 € | ||
| 50mg | 1,874.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
GSK1702934A
CAS:924377-85-5
GSK1702934A is a TRPC3 agonist with pro-arrhythmic and positive inotropic effects and is used in …
Formula:
C22H25N3O2S
Purity:
98.15%
Color and Shape:
Solid
Molecular weight:
395.52
Ref: TM-T15425
| 1mg | 77.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
TRPC6-PAM-C20
CAS:667427-75-0
TRPC6-PAM-C20, a selective enhancer for TRPC6, boosts calcium in HEK cells and OAG-related platelet clumping, …
Formula:
C22H21NO4
Purity:
90%
Color and Shape:
Liquid
Molecular weight:
363.41
Ref: TM-T37428
| 1mg | 171.00 € | ||
| 5mg | 424.00 € | ||
| 10mg | 628.00 € | ||
| 25mg | 988.00 € | ||
| 50mg | 1,327.00 € | ||
| 1mL*10mM (DMSO) | 461.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
ABT-239
CAS:460746-46-7
ABT-239 is a novel, highly efficacious antagonist belonging to the non-imidazole class of histamine H3 …
Formula:
C22H22N2O
Purity:
100%
Color and Shape:
Solid
Molecular weight:
330.42
Ref: TM-T14087
| 1mg | 47.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 166.00 € | ||
| 25mg | 348.00 € | ||
| 50mg | 518.00 € | ||
| 100mg | 732.00 € | ||
| 500mg | 1,537.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
D-3263 hydrochloride
CAS:1008763-54-9
D-3263 hydrochloride (D3263 HCl salt) is enteric-coated, orally bioavailable transient receptor potential melatonin member 8 …
Formula:
C21H32ClN3O3
Purity:
99.85%
Color and Shape:
Solid
Molecular weight:
409.95
Ref: TM-T10929L
| 1mg | 50.00 € | ||
| 5mg | 72.00 € | ||
| 10mg | 103.00 € | ||
| 25mg | To inquire | ||
| 50mg | To inquire | ||
| 1mL*10mM (DMSO) | 64.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
