Glucokinase
Glucokinase (GK) is an enzyme that catalyzes the phosphorylation of glucose to glucose-6-phosphate, a critical step in glycolysis. GK is predominantly expressed in the liver and pancreas, where it plays a key role in regulating blood glucose levels. Inhibitors of GK are of interest in the study of metabolic disorders such as diabetes, as they can modulate glucose metabolism and insulin secretion. At CymitQuimica, we provide glucokinase inhibitors to support your research in diabetes, metabolism, and therapeutic development.
Found 56 products of "Glucokinase"
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MK-0941 free base
CAS:MK-0941: an oral glucokinase activator for type 2 diabetes with potent glucose-lowering effects.Formula:C21H24N4O6SPurity:98.75%Color and Shape:SolidMolecular weight:460.5Dorzagliatin
CAS:Dorzagliatin (HMS5552) is a dual-acting glucokinase (GK) activator. It also improves glycaemic control and pancreatic β-cell function in type 2 diabetes.Formula:C22H27ClN4O5Purity:98.67% - 99.45%Color and Shape:SolidMolecular weight:462.93Oxfendazole
CAS:Oxfendazole (RS-8858), a broad spectrum benzimidazole anthelmintic, protects livestock against roundworm, strongyles and pinworms.Formula:C15H13N3O3SPurity:98.99% - 99.17%Color and Shape:White To Yellowish PowderMolecular weight:315.35WAY-640509
CAS:<p>WAY-640509 is a glucocerebrosidase inhibitor.</p>Formula:C25H23N5O4SPurity:99.36%Color and Shape:SolidMolecular weight:489.55MitoPQ
CAS:MitoPQ (MitoParaquat) inhibits insulin-stimulated glucose uptake and plasma membrane translocation in myotubes and can be used to study oxidative stress.Formula:C39H46I3N2PPurity:99.87% - 99.91%Color and Shape:SolidMolecular weight:954.48KAN0438757
CAS:<p>KAN0438757 is a selective and potent inhibitor of the metabolic kinase PFKFB3 with an IC50 of 0.19 μM.</p>Formula:C21H18FNO7SPurity:99.34%Color and Shape:SolidMolecular weight:447.43ML251
CAS:ML251, potent inhibitor, targets T. brucei PFK (IC50=0.37μM) & T. cruzi PFK (IC50=0.13μM), aids parasite research.Formula:C17H13Cl2N3O4SPurity:99.87%Color and Shape:SolidMolecular weight:426.27WAY-615145
CAS:WAY-615145 is a compound that activates glucokinase.Formula:C16H18N2OSMolecular weight:286.39ML266
CAS:<p>ML266: GCase chaperone, non-inhibiting, IC50=2.5 µM, aids mutant protein transport, may help in Gaucher disease study.</p>Formula:C24H22BrN3O4Purity:99.58%Color and Shape:SolidMolecular weight:496.35AP-III-a4 hydrochloride
CAS:<p>AP-III-a4 hydrochloride (ENOblock hydrochloride) is a direct enolase (enolase) inhibitor that inhibit metastasis and affect glucose homeostasis.</p>Formula:C31H44ClFN8O3Purity:98%Color and Shape:SolidMolecular weight:631.18ADP-specific glucokinase
CAS:<p>ADP-specific glucokinase, expressed in thermophilic archaea, is an ADP-specific enzyme that catalyzes the conversion of glucose to glucose-6-phosphate, thereby facilitating glycolysis. This enzyme can activate T cells and enhance the phagocytic activity of macrophages. It is used in research related to metabolic disorders, neurological diseases, and tumors.</p>Color and Shape:SolidNeuron-specific enolase, Human
Neuron-specific enolase, Human (EC 4.2.1.11), is an enolase enzyme that serves as a biomarker for traumatic brain injury (TBI), stroke following cardiac arrest, hypoxic encephalopathy, and acute spinal cord injury (SCI).Color and Shape:Odour Solid(1S,2R)-Globalagliatin
CAS:(1S,2R)-Globalagliatin is a highly potent glucokinase (GK) activator for the study of type 2 diabetes.Formula:C28H37N3O3S3Purity:99.09% - 99.17%Color and Shape:SoildMolecular weight:559.81PF-04991532
CAS:PF-04991532 is a hepatoselective glucokinase activator that reduces plasma glucose and AMP concentrations in the Goto-Kakizaki rat model.Formula:C18H19F3N4O3Purity:99.99%Color and Shape:SolidMolecular weight:396.36Cadisegliatin
CAS:Cadisegliatin (TTP-399) may activate liver GK to lower blood sugar in type 2 diabetes studies.Formula:C21H33N3O4S2Color and Shape:SolidMolecular weight:455.63Anti-Glucokinase Antibody (3U461)
Anti-Glucokinase Antibody (3U461) is a Rabbit antibody targeting Glucokinase. Anti-Glucokinase Antibody (3U461) can be used in ELISA.Color and Shape:Odour Liquid5MPN
CAS:<p>5MPN is a PFKFB4 inhibitor that inhibits the F6P binding site and suppresses the proliferation of myeloma cells.</p>Formula:C15H19N3O4Purity:98.92% - 99.69%Color and Shape:SolidMolecular weight:305.33Anti-Glucokinase Antibody (5Q209)
Anti-Glucokinase Antibody (5Q209) is a Mouse antibody targeting Glucokinase. Anti-Glucokinase Antibody (5Q209) can be used in ELISA.Color and Shape:Odour LiquidHex
CAS:Hex is a potent inhibitor of enolase, exhibiting inhibitory activity with Ki values of 74.4 nM and 269.4 nM against ENO2 and ENO1, respectively.Formula:C5H10NO5PColor and Shape:SolidMolecular weight:195.11Glucokinase Protein, Human, Recombinant
Glucokinase belongs to the bacterial glucokinase family.Color and Shape:Lyophilized PowderMolecular weight:52.2 kDa (predicted); 52.2 kDa (reducing conditions)
