Glucokinase
Glucokinase (GK) is an enzyme that catalyzes the phosphorylation of glucose to glucose-6-phosphate, a critical step in glycolysis. GK is predominantly expressed in the liver and pancreas, where it plays a key role in regulating blood glucose levels. Inhibitors of GK are of interest in the study of metabolic disorders such as diabetes, as they can modulate glucose metabolism and insulin secretion. At CymitQuimica, we provide glucokinase inhibitors to support your research in diabetes, metabolism, and therapeutic development.
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Oxfendazole
CAS:53716-50-0
Oxfendazole (RS-8858), a broad spectrum benzimidazole anthelmintic, protects livestock against roundworm, strongyles and pinworms.
Formula:
C15H13N3O3S
Purity:
98.81% - 98.99%
Color and Shape:
White To Yellowish Powder
Molecular weight:
315.35
Ref: TM-T0714
| 1g | 70.00 € | ||
| 5g | 126.00 € | ||
| 10g | 185.00 € | ||
| 200mg | 37.00 € | ||
| 500mg | 49.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Dorzagliatin
CAS:1191995-00-2
Dorzagliatin (HMS5552) is a dual-acting glucokinase (GK) activator. It also improves glycaemic control and pancreatic …
Formula:
C22H27ClN4O5
Purity:
98.52% - 98.67%
Color and Shape:
Solid
Molecular weight:
462.93
Ref: TM-T15159
| 1mg | 40.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 85.00 € | ||
| 10mg | 121.00 € | ||
| 25mg | 235.00 € | ||
| 50mg | 369.00 € | ||
| 100mg | 555.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
MK-0941 free base
CAS:752240-01-0
MK-0941: an oral glucokinase activator for type 2 diabetes with potent glucose-lowering effects.
Formula:
C21H24N4O6S
Purity:
98.55%
Color and Shape:
Solid
Molecular weight:
460.5
Ref: TM-T12056
| 1mg | 85.00 € | ||
| 5mg | 169.00 € | ||
| 10mg | 252.00 € | ||
| 25mg | 416.00 € | ||
| 50mg | 585.00 € | ||
| 100mg | 791.00 € | ||
| 1mL*10mM (DMSO) | 207.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
KAN0438757
CAS:1451255-59-6
KAN0438757 is a selective and potent inhibitor of the metabolic kinase PFKFB3 with an IC50 …
Formula:
C21H18FNO7S
Purity:
99.34%
Color and Shape:
Solid
Molecular weight:
447.43
Ref: TM-T11741
| 1mg | 100.00 € | ||
| 5mg | 190.00 € | ||
| 10mg | 303.00 € | ||
| 25mg | 547.00 € | ||
| 50mg | 752.00 € | ||
| 100mg | 1,023.00 € | ||
| 1mL*10mM (DMSO) | 204.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
WAY-640509
CAS:851185-20-1
WAY-640509 is a glucocerebrosidase inhibitor.
Formula:
C25H23N5O4S
Purity:
98.59%
Color and Shape:
Liquid
Molecular weight:
489.55
Ref: TM-T60048
| 1mg | 113.00 € | ||
| 2mg | 169.00 € | ||
| 5mg | 249.00 € | ||
| 10mg | 367.00 € | ||
| 25mg | 550.00 € | ||
| 50mg | 769.00 € | ||
| 100mg | 1,049.00 € | ||
| 500mg | 2,108.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
MitoPQ
CAS:1821370-28-8
MitoPQ (MitoParaquat) inhibits insulin-stimulated glucose uptake and plasma membrane translocation in myotubes and can be …
Formula:
C39H46I3N2P
Purity:
≥98%
Color and Shape:
Solid
Molecular weight:
954.48
Ref: TM-T33412
| 1mg | 48.00 € | ||
| 5mg | 93.00 € | ||
| 10mg | 150.00 € | ||
| 25mg | 223.00 € | ||
| 50mg | 351.00 € | ||
| 100mg | 545.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
(1S,2R)-Globalagliatin
CAS:2514278-46-5
(1S,2R)-Globalagliatin is a highly potent glucokinase (GK) activator for the study of type 2 diabetes.
Formula:
C28H37N3O3S3
Purity:
98.31% - 99.00%
Color and Shape:
Soild
Molecular weight:
559.81
Ref: TM-T3104L
| 1mg | 49.00 € | ||
| 5mg | 96.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
ML251
CAS:1486482-16-9
ML251, potent inhibitor, targets T. brucei PFK (IC50=0.37μM) & T. cruzi PFK (IC50=0.13μM), aids parasite …
Formula:
C17H13Cl2N3O4S
Purity:
99.87%
Color and Shape:
Solid
Molecular weight:
426.27
Ref: TM-T64320
| 1mg | 130.00 € | ||
| 5mg | 270.00 € | ||
| 10mg | 423.00 € | ||
| 25mg | 704.00 € | ||
| 50mg | 985.00 € | ||
| 100mg | 1,333.00 € | ||
| 500mg | 2,672.00 € | ||
| 1mL*10mM (DMSO) | 300.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
ML266
CAS:1462267-08-8
ML266: GCase chaperone, non-inhibiting, IC50=2.5 µM, aids mutant protein transport, may help in Gaucher disease …
Formula:
C24H22BrN3O4
Purity:
98.45%
Color and Shape:
Solid
Molecular weight:
496.35
Ref: TM-T8990
| 1mg | 52.00 € | ||
| 2mg | 73.00 € | ||
| 5mg | 110.00 € | ||
| 10mg | 167.00 € | ||
| 25mg | 340.00 € | ||
| 50mg | 467.00 € | ||
| 100mg | 680.00 € | ||
| 500mg | 1,411.00 € | ||
| 1mL*10mM (DMSO) | 120.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
ADP-specific glucokinase
CAS:173585-07-4
ADP-specific glucokinase, expressed in thermophilic archaea, is an ADP-specific enzyme that catalyzes the conversion of …
Color and Shape:
Liquid
Ref: TM-T89882
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
Glucokinase Protein, Human, Recombinant
Glucokinase belongs to the bacterial glucokinase family.
Color and Shape:
Solid
Molecular weight:
52.2 kDa (predicted); 52.2 kDa (reducing conditions)
Ref: TM-TMPY-04394
| 50µg | 499.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
POMHEX
CAS:2004714-34-3
Pomhex, a cell-penetrating ENO2 inhibitor, thwarts glycolysis to combat ENO1-deficient tumors.
Formula:
C17H30NO9P
Purity:
99.88%
Color and Shape:
Solid
Molecular weight:
423.4
Ref: TM-T36491
| 1mg | 143.00 € | ||
| 5mg | 338.00 € | ||
| 10mg | 501.00 € | ||
| 25mg | 811.00 € | ||
| 50mg | 1,096.00 € | ||
| 100mg | 1,505.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PF-04991532
CAS:1215197-37-7
PF-04991532 is an effective, hepatoselective glucokinase activator. It has EC50s of 80 and 100 nM …
Formula:
C18H19F3N4O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
396.36
Ref: TM-T16480
| 2mg | 84.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
3PO
CAS:18550-98-6
3PO inhibits PFKFB3 (IC50: 22.9 µM) and cancer cell growth (IC50: 1.4-24 µM), reducing glucose …
Formula:
C13H10N2O
Purity:
97.76% - 99.67%
Color and Shape:
Solid
Molecular weight:
210.23
Ref: TM-T22223
| 5mg | 56.00 € | ||
| 10mg | 80.00 € | ||
| 25mg | 124.00 € | ||
| 50mg | 184.00 € | ||
| 100mg | 333.00 € | ||
| 200mg | 495.00 € | ||
| 500mg | 794.00 € | ||
| 1mL*10mM (DMSO) | 64.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Globalagliatin
CAS:1234703-40-2
Globalagliatin (LY2608204) has been used in trials studying the treatment of Diabetes Mellitus, Type 2.
Formula:
C28H37N3O3S3
Purity:
98% - 99.41%
Color and Shape:
Solid
Molecular weight:
559.81
Ref: TM-T3104
| 1mg | 38.00 € | ||
| 2mg | 49.00 € | ||
| 5mg | 80.00 € | ||
| 10mg | 96.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
PFK-015
CAS:4382-63-2
PFK-015 (PFK15) is an effective inhibitor of PFKFB3 (IC50: 110 nM) and inhibits PFKFB3 activity …
Formula:
C17H12N2O
Purity:
98.94% - 99.7%
Color and Shape:
Solid
Molecular weight:
260.29
Ref: TM-T2455
| 5mg | 56.00 € | ||
| 10mg | 88.00 € | ||
| 25mg | 157.00 € | ||
| 50mg | 276.00 € | ||
| 100mg | 412.00 € | ||
| 200mg | 572.00 € | ||
| 500mg | 910.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
(E)-3PO
CAS:13309-08-5
(E)-3PO is a PFKFB3 (6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase) inhibitor.
Formula:
C13H10N2O
Purity:
98.8% - 98.8%
Color and Shape:
Solid
Molecular weight:
210.23
Ref: TM-T3260
| 1mg | 35.00 € | ||
| 2mg | 47.00 € | ||
| 5mg | 67.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 162.00 € | ||
| 50mg | 283.00 € | ||
| 100mg | 510.00 € | ||
| 1mL*10mM (DMSO) | 67.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Palmitelaidic Acid
CAS:10030-73-6
Palmitelaidic Acid (trans-Palmitoleic acid) is one of the most abundant fatty acids in serum and …
Formula:
C16H30O2
Purity:
99.36%
Color and Shape:
Solid
Molecular weight:
254.41
Ref: TM-T19500
| 10mg | 86.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
AM-2394
CAS:1442684-77-6
AM-2394 is an effective and specific Glucokinase agonist (GKA, EC50: 60 nM), which catalyzes the …
Formula:
C22H25N5O4
Purity:
99.01% - 99.62%
Color and Shape:
Solid
Molecular weight:
423.46
Ref: TM-T3312
| 2mg | 44.00 € | ||
| 5mg | 64.00 € | ||
| 10mg | 93.00 € | ||
| 25mg | 173.00 € | ||
| 50mg | 272.00 € | ||
| 100mg | 416.00 € | ||
| 1mL*10mM (DMSO) | 71.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Genz-123346 free base
CAS:491833-30-8
Genz 123346 is an inhibitor of GL1 synthase that blocks the conversion of ceramide to …
Formula:
C24H38N2O4
Purity:
99.23%
Color and Shape:
Solid
Molecular weight:
418.57
Ref: TM-T4049
| 5mg | 50.00 € | ||
| 10mg | 73.00 € | ||
| 25mg | 122.00 € | ||
| 50mg | 183.00 € | ||
| 100mg | 272.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
