Casein Kinase
Casein kinases are a family of serine/threonine protein kinases that regulate various cellular processes, including DNA repair, circadian rhythms, and signal transduction. These kinases are involved in the phosphorylation of numerous proteins and are implicated in diseases such as cancer, neurodegenerative disorders, and metabolic syndromes. At CymitQuimica, we offer a selection of casein kinase inhibitors to support your research in signal transduction, cell cycle regulation, and therapeutic development.
Found 141 products for "Casein Kinase".
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Ellagic acid
CAS:Ellagic acid (Gallogen), a thickened tetracyclic natural product, is a potent CK2 inhibitor. Ellagic acid is an antioxidant. Cost-effective and quality-assured.Formula:C14H6O8Purity:97.11% - 99.75%Color and Shape:Brown SolidMolecular weight:302.19Emodin
CAS:Emodin (Frangula emodin) is a selective 11β-HSD1 inhibitor,IC50 of 186 and 86 nM against 11β-HSD1 in humans and mice. High-Quality, Low-Cost!Formula:C15H10O5Purity:98.37% - 99.53%Color and Shape:Physical Description Orange Needles Or Powder (Ntp 1992)Molecular weight:270.24Silmitasertib sodium salt
CAS:Silmitasertib sodium salt (CX-4945 sodium salt) is a potent and orally bioavailable, highly selective inhibitor of CK2(IC50 of 1 nM, CK2α).Formula:C19H11ClN3NaO2Purity:99.49% - 99.62%Color and Shape:SolidMolecular weight:371.75NMS-P715
CAS:NMS-P715 is a highly selective and ATP-competitive MPS1 inhibitor(IC50 of 182 nM).Formula:C35H39F3N8O3Purity:99.84%Color and Shape:SolidMolecular weight:676.73A-3 hydrochloride
CAS:A-3 hydrochloride: potent, reversible kinase antagonist; permeable; inhibits PKC, CKI, PKA, CKII, MLCK; Ki: 4.3-80 μM.Formula:C12H14Cl2N2O2SPurity:99.32%Color and Shape:SolidMolecular weight:321.22Ref: TM-T14069
1mg34.00€5mg63.00€10mg90.00€1mL*10mM (DMSO)95.00€25mg161.00€50mg260.00€100mg416.00€500mg888.00€TBCA
CAS:TBCA: selective CK2 inhibitor, IC50=110 nM, Ki=77 nM, favors CK2 over CK1, DYRK1A, and 27 other kinases.Formula:C9H4Br4O2Purity:99.3%Color and Shape:SolidMolecular weight:463.74Ac-ESMD-CHO
CAS:Ac-ESMD-CHO functions as an inhibitor of both caspase-3 and caspase-7, specifically obstructing the proteolytic cleavage of the caspase-3 precursor peptide (Formula:C19H30N4O10SPurity:98%Color and Shape:SolidMolecular weight:506.53CK1δ/CK1ε liagnd-1
CK1δ/CK1ε ligand-1 is a ligand of CK1δ/CK1ε and can serve as a target protein ligand for the synthesis of the CK1 PROTAC degrader AH078.Formula:C21H20F2N6Color and Shape:SolidMolecular weight:394.42Casein kinase 1δ-IN-7
CAS:Casein kinase 1δ-IN-7 is a Casein kinase 1δ inhibitor for neurodegenerative diseases such as Alzheimer's disease.Formula:C17H14N4O2SPurity:98.02%Color and Shape:SolidMolecular weight:338.38CK2-IN-14
CK2-IN-14 (Compound 10b) is an inhibitor of cyclin-dependent kinase 2α with an IC50 of 36.7 nM. It effectively hinders the growth of cancer cell lines 786-O and U937, with GI50 values of 7.3 μM and 7.5 μM, respectively.Formula:C19H20ClN5SColor and Shape:SolidMolecular weight:385.91Casein kinase 1δ-IN-15
CAS:Casein kinase 1δ-IN-15, an inhibitor for casein kinase 1 (CK1δ), exhibits an IC50 of 0.045 μM [1].Formula:C19H17FN6OColor and Shape:SolidMolecular weight:364.38CSNK2-IN-2
CSNK2-IN-2 (compound 2) is an orally active inhibitor of CSNK2. It is utilized in antiviral research.Formula:C25H30FN9OColor and Shape:SolidMolecular weight:491.56Casein kinase 1δ-IN-9
CAS:Casein kinase 1δ-IN-9 is a Quinone reductase 2 inhibitor with IC50 of 0.6μM.Formula:C15H12ClN3Purity:99.93%Color and Shape:White SolidMolecular weight:269.73Ref: TM-T64376
1mg64.00€1mL*10mM (DMSO)124.00€5mg136.00€10mg197.00€25mg314.00€50mg424.00€100mg562.00€200mg743.00€AH081
AH081 (Compound 38) is a CK1δ/ε PROTAC degrader and serves as the negative control for AH078. It maintains inhibitory activity against CK1δ/ε but lacks degradation activity due to the use of an inactive stereoisomer of the VHL ligand.Color and Shape:Odour SolidCasein Kinase Substrates 3
CAS:Casein Kinase Substrates 3 is a substrate of casein kinase.Formula:C85H139N27O35SPurity:98%Color and Shape:SolidMolecular weight:2131.24CK1-IN-3
CAS:WAY-296817 inhibits CK1, potential for circadian rhythm and inflammation research.Formula:C17H16N2O3SPurity:99.18%Color and Shape:SolidMolecular weight:328.39Ref: TM-T60005
1mg34.00€5mg71.00€1mL*10mM (DMSO)78.00€10mg96.00€25mg170.00€50mg244.00€100mg334.00€200mg460.00€Casein kinase 1δ-IN-6
CAS:CK1δ-IN-6: potent, selective CK-1δ inhibitor, IC50 23 nM, neuroprotective, anti-inflammatory, for neurodegenerative research.Formula:C16H10ClF3N2OSPurity:99.87%Color and Shape:SolidMolecular weight:370.78Casein kinase 1δ-IN-3
CAS:Casein kinase 1δ-IN-3 (Casein kinase 1δ-IN-3) (Compound 23a) is a casein kinase 1 delta (CK1d) inhibitor with a pIC50 of 6.5376 M.Formula:C17H16N2O2SPurity:98.94%Color and Shape:SoildMolecular weight:312.39CK2-IN-15
CK2-IN-15 (Compound Biv5) is a selective and potent inhibitor of the enzyme protein kinase CK2, with an IC50 value of 51 pM. It significantly reduces the replication of SARS-CoV-2 in HEK-ACE2-TMPRSS2 and Vero cells, and also decreases viral replication in an in vitro model of human nasal epithelial cells. CK2-IN-15 holds potential for research into diseases related to β-coronavirus infections.Color and Shape:Odour SolidMU1742
MU1742 is a probe for CK1δ and CK1ε protein kinases [1] .Formula:C22H22F2N6Color and Shape:SolidMolecular weight:408.45WAY-297174
CAS:WAY-297174 is a human protein kinase CK2 inhibitor with IC50 of > 33 μM.Formula:C11H12N2O2S2Purity:99.53%Color and Shape:SoildMolecular weight:268.36Casein kinase 1δ-IN-8
CAS:Casein kinase 1δ-IN-8 is an inhibitor of casein kinase 1δ and is used to treat neurodegenerative diseases such as Alzheimer's disease type.Formula:C19H14FN5OSPurity:99.56%Color and Shape:SolidMolecular weight:379.41Casein Kinase 2 Substrate Peptide
CAS:CK2 Substrate Peptide, C-terminus linked to EDANS, used for CK2 activity assays.Formula:C45H73N19O24Color and Shape:SolidMolecular weight:1264.17CK1-IN-4
CK1-IN-4 (Compound 59) is an inhibitor of casein kinase CK1δ with an IC50 of 2.74 μM. It exhibits neuroprotective activity in SH-SY5Y cells treated with Ethacrynic acid.Color and Shape:Odour SolidEllagic acid (hydrate)
CAS:Ellagic acid (hydrate) is a natural antioxidant and acts as a potent and ATP-competitive CK2 inhibitor (IC50:40 nM, Ki: 20 nM).Formula:C14H8O9Purity:98%Color and Shape:SolidMolecular weight:320.21QXG-6442
QXG-6442 is a molecular glue degrader targeting CK1α, demonstrating a degradation potency with a DC50 of 5.7 nM and a Dmax of 90%. In the MOLM-14 cell line, QXG-6442 induces antiproliferative effects.Formula:C21H17N5O4Color and Shape:SolidMolecular weight:403.39Casein kinase 1δ-IN-14
CAS:Casein kinase 1δ-IN-14 (WAY-637081) can be used to study atherosclerosis-related cardiovascular disease.Formula:C17H11ClN4O2Purity:99.66%Color and Shape:SolidMolecular weight:338.75Casein
CAS:Casein is a milk protein with multiple roles involved in novel drug delivery systems.Purity:95%Color and Shape:SolidCK2-IN-13
CK2-IN-13 (compound 12c) is a potent inhibitor of CK2, with an IC50 value of 5.8 nM, playing a significant role in cancer research.Formula:C19H13Br2NO3Color and Shape:SolidMolecular weight:463.119AH078
AH078 (compound 37) is a selective PROTAC degrader targeting CK1δ and CK1ε with low selectivity for CK1α. AH078 consists of a PROTAC linker (black part) Monomethyl octanoate, a target protein ligand (red part) CK1δ/CK1ε ligand-1, and an E3 ligase ligand (blue part) E3 Ligase Ligand 58. The E3 ligase ligand combined with the linker forms the conjugate E3 Ligase Ligand-linker Conjugate 163.Formula:C51H60F2N10O5SColor and Shape:SolidMolecular weight:963.15CZP-IN-1
CZP-IN-1 (compound SH-1) is an inhibitor targeting the pathogen Trypanosoma cruzi protease (CZP) without affecting cathepsin L (IC50=28 nM). This compound is applicable in Chagas disease research.Formula:C20H26N4O4SColor and Shape:SolidMolecular weight:418.51GSK-3β/CK-1δ-IN-1
GSK-3β/CK-1δ-IN-1 (8d) is a dual inhibitor of GSK-3β and CK-1δ that can cross the blood-brain barrier, with IC50 values of 0.77 μM and 0.57 μM, respectively. GSK-3β/CK-1δ-IN-1 (8d) is applicable in neuroblastoma research.Formula:C22H17F3N4OColor and Shape:SolidMolecular weight:410.39FPFT-2216
CAS:FPFT-2216 is a "molecular glue" compound with potential anti-tumor activity that degrades IKZF6, IKZF1, DE1D and can be used to study immune system diseases.Formula:C12H12N4O3SPurity:99.35% - 99.62%Color and Shape:SolidMolecular weight:292.31Ref: TM-T60608
1mg92.00€5mg222.00€1mL*10mM (DMSO)236.00€10mg334.00€25mg708.00€50mg1,108.00€100mg1,783.00€200mg2,412.00€MRT00033659
CAS:MRT00033659 inhibits CK1 (IC50=0.9 μM), CHK1 (IC50=0.23 μM), activates p53, and destabilizes E2F-1; it's a pyrazolo-pyridine.Formula:C15H14N4OColor and Shape:SolidMolecular weight:266.3SGC-CK2-1
CAS:SGC-CK2-1, a CK2 inhibitor, is a inducer of insulin production and secretion in pancreatic β-cells.Formula:C20H21N7OPurity:99.41%Color and Shape:SolidMolecular weight:375.43PF-5006739
CAS:PF-5006739 is a selective CK1δ/ε inhibitor for psychiatric disorder and metabolic research.Formula:C22H22FN7OPurity:98%Color and Shape:SolidMolecular weight:419.45PF-670462
CAS:PF-670462 is a potent (IC50 = 7.7 ± 2.2 nM) and selective (>30-fold with respect to 42 additional kinases) inhibitor of CK1ε in isolated enzyme preparations.Formula:C19H22Cl2FN5Purity:99.42% - 99.72%Color and Shape:SolidMolecular weight:410.32SR-3029
CAS:SR-3029 is a potent and highly specific CK1δ/CK1ε inhibitor.Formula:C23H19F3N8OPurity:99.64%Color and Shape:SolidMolecular weight:480.45CK1-IN-1
CAS:CK1-IN-1, a CK1 inhibitor with IC50: 15nM CK1δ, 16nM CK1ε, 73nM p38σ; patent WO2015119579A1.Formula:C24H15F2N3Purity:98.79%Color and Shape:SolidMolecular weight:383.39Ref: TM-T5393
1mg47.00€2mg62.00€5mg92.00€1mL*10mM (DMSO)101.00€10mg152.00€25mg289.00€50mg447.00€100mg670.00€Longdaysin
CAS:Longdaysin is an inhibitor of CK1α and CK1δ (IC50s: 5.6/8.8 μM). It also can inhibit ERK2 (IC50: 52 μM).Formula:C16H16F3N5Purity:99.97%Color and Shape:SolidMolecular weight:335.33(E/Z)-GO289
CAS:(E/Z)-GO289, which strongly lengthened circadian period, is a potent and selective inhibitor of CK2.Formula:C17H15BrN4O2SPurity:98.1%Color and Shape:SolidMolecular weight:419.3Ref: TM-T9356
2mg34.00€5mg52.00€1mL*10mM (DMSO)54.00€10mg86.00€25mg170.00€50mg250.00€100mg354.00€200mg482.00€TBB
CAS:TBB (NSC-231634)(NSC-231634) is a highly selective, ATP/GTP-competitive inhibitor of casein kinase-2 (CK2).Formula:C6HBr4N3Purity:98.51% - 99.45%Color and Shape:Off-White SolidMolecular weight:434.71Umbralisib hydrochloride
CAS:Umbralisib hydrochloride: PI3Kδ inhibitor; IC50=22.2 nM, EC50=24.3 nM; active vs CK1ε, EC50=6.0 μM.Formula:C31H25ClF3N5O3Purity:98%Color and Shape:SolidMolecular weight:608.01LY-364947
CAS:LY-364947 (HTS466284) is a potent ATP-competitive inhibitor of TGFβR-I.Formula:C17H12N4Purity:99.65% - 99.96%Color and Shape:Yellow SolidMolecular weight:272.3Ref: TM-T2048
5mg62.00€1mL*10mM (DMSO)69.00€10mg78.00€25mg136.00€50mg241.00€100mg354.00€200mg530.00€500mg830.00€TAK-715
CAS:TAK-715 is a p38 MAPK inhibitor for p38α.Formula:C24H21N3OSPurity:99.83%Color and Shape:White SolidMolecular weight:399.51Ref: TM-T6150
1mg38.00€2mg50.00€5mg82.00€1mL*10mM (DMSO)92.00€10mg94.00€25mg166.00€50mg306.00€100mg480.00€TTP 22
CAS:TTP 22: ATP-competitive CK2 inhibitor; IC50/Ki: 0.1 μM/40 nM; >250x selective over JNK3, ROCK1, MET.Formula:C16H14N2O2S2Purity:97.08% - 97.78%Color and Shape:SolidMolecular weight:330.42Silmitasertib
CAS:Silmitasertib (CX-4945) is a potent, orally bioavailable inhibitor of casein kinase 2 (CK2; Ki: 0.38 nM).Formula:C19H12ClN3O2Purity:98% - 99.90%Color and Shape:SolidMolecular weight:349.77Ref: TM-T2259
1mg38.00€2mg49.00€5mg80.00€1mL*10mM (DMSO)88.00€10mg118.00€25mg197.00€50mg313.00€100mg492.00€500mg1,054.00€Umbralisib
CAS:Umbralisib (TGR 1202) is a PI3Kδ inhibitor.Formula:C31H24F3N5O3Purity:99.56% - 99.56%Color and Shape:White SolidMolecular weight:571.55Ref: TM-T4976
1mg46.00€2mg62.00€5mg90.00€1mL*10mM (DMSO)114.00€10mg166.00€25mg324.00€50mg425.00€100mg623.00€IWP-2
CAS:IWP-2 is a Wnt pathway inhibitor and an ATP-competitive CK1δ inhibitor. IWP-2 inhibits self-renewal of embryonic stem cells. Cost effective and quality assured.Formula:C22H18N4O2S3Purity:96.1% - 99.49%Color and Shape:White SolidMolecular weight:466.6DMAT
CAS:DMAT (Casein kinase II Inhibitor) is a potent and specific inhibitor of CK2(IC50 value of 130 nM).Formula:C9H7Br4N3Purity:99.48%Color and Shape:White SolidMolecular weight:476.79
