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IDO

IDO

Indoleamine 2,3-dioxygenase (IDO) is an enzyme involved in the catabolism of tryptophan, leading to the production of kynurenine and other metabolites. IDO plays a role in immune tolerance and is often upregulated in cancer and chronic inflammatory conditions. Inhibitors of IDO are being explored as potential immunotherapeutic agents in cancer and autoimmune diseases. At CymitQuimica, we provide IDO inhibitors to support your research in immunology, oncology, and metabolic regulation.

Found 82 products of "IDO"

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  • (Rac)-IDO1-IN-5

    CAS:
    <p>(Rac)-IDO1-IN-5 is a racemic, potent IDO1 inhibitor; selective for apo-IDO1, it crosses the blood-brain barrier.</p>
    Formula:C23H25FN2O3
    Color and Shape:Solid
    Molecular weight:396.45
  • IDO1/TDO-IN-4

    CAS:
    <p>IDO1/TDO-IN-4 is a novel dual inhibitor of IDO1/TDO with antidepressant activity, forming hydrogen bonds with IDO1 and π-π stacking interactions with TDO.</p>
    Formula:C14H10N4
    Purity:98.88%
    Color and Shape:Solid
    Molecular weight:234.26
  • Anti-IDO1 Antibody (9Y885)


    <p>Anti-IDO1 Antibody (9Y885) is an antibody targeting IDO1. Anti-IDO1 Antibody (9Y885) can be used in ELISA, IHC.</p>
    Color and Shape:Odour Liquid
  • IDO1 Protein, Mouse, Recombinant (His)


    <p>IDO Protein, Mouse, Recombinant (His) is expressed in E.</p>
    Purity:≥ 90 % as determined by SDS-PAGE. - ≥ 90 % as determined by SDS-PAGE.
    Color and Shape:Lyophilized Powder
    Molecular weight:46.47 kDa (predicted)
  • IDO1 Protein, Human, Recombinant


    <p>IDO Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 45.2 kDa and the accession number is A0A348GSI3.</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:45.2 kDa (predicted); 46 kDa (reducing conditions)
  • (S)-IDO1-IN-5

    CAS:
    <p>(S)-IDO1-IN-5 is an active S-isomer of IDO1-IN-5. (S)-IDO1-IN-5 binds to IDOL(IC50 value less than 1.5 μΜ).</p>
    Formula:C23H25FN2O3
    Color and Shape:Solid
    Molecular weight:396.45
  • IDO1 Protein, Human, Recombinant (His)


    <p>IDO Protein, Human, Recombinant (His) is expressed in E.</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:46 kDa (predicted); 44 kDa (reducing conditions)
  • Epacadostat

    CAS:
    <p>Epacadostat (INCB 024360) is an oral, potent and selective IDO1 inhibitor with IC50 value of 71.8 nM.Cost-effective and quality-assured.</p>
    Formula:C11H13BrFN7O4S
    Purity:98% - >99.99%
    Color and Shape:Solid
    Molecular weight:438.23
  • PF-06840003

    CAS:
    <p>PF-06840003 (EOS200271) is a specific and oral active IDO-1 inhibitor.</p>
    Formula:C12H9FN2O2
    Purity:99.10%
    Color and Shape:Solid
    Molecular weight:232.21
  • IDO-IN-7

    CAS:
    <p>IDO-IN-7 (NLG-919 analogue) is a potent IDO (indoleamine-(2, 3)-dioxygenase) pathway inhibitor.</p>
    Formula:C18H22N2O
    Purity:99.32% - 99.9%
    Color and Shape:Solid
    Molecular weight:282.38
  • 3-TYP

    CAS:
    <p>3-TYP (3-(1H-1,2,3-triazol-4-yl) pyridine) is a selective SIRT3 inhibitor.</p>
    Formula:C7H6N4
    Purity:99.16% - >99.99%
    Color and Shape:Solid
    Molecular weight:146.15
  • IDO5L

    CAS:
    <p>IDO5L (INCB024360 analogue) is an effective IDO1 inhibitor(IC50=10 nM).</p>
    Formula:C9H7ClFN5O2
    Purity:99.49% - 99.75%
    Color and Shape:Solid
    Molecular weight:271.64
  • Linrodostat

    CAS:
    <p>Linrodostat (BMS-986205) is a selective indoleamine 2, 3-dioxygenase 1 (IDO1) inhibitor.</p>
    Formula:C24H24ClFN2O
    Purity:99.54% - 99.71%
    Color and Shape:Solid
    Molecular weight:410.91
  • BMS-986242

    CAS:
    <p>BMS-986242 is an orally active, potent and selective inhibitor of indoleamine-2,3-dioxygenase 1 (IDO1), and it can be used for the research of cancer.</p>
    Formula:C24H24ClFN2O
    Purity:98.9%
    Color and Shape:Solid
    Molecular weight:410.91
  • Necrostatin 2 racemate

    CAS:
    <p>Necrostatin 2 racemate (Necrostatin-2 racemate) is an potent and specific inhibitor of RIPK1.</p>
    Formula:C13H12ClN3O2
    Purity:98% - 99.5%
    Color and Shape:Solid
    Molecular weight:277.71
  • (S)-Indoximod

    CAS:
    <p>(S)-Indoximod (L-Abrine) is an indoleamine-2,3-dioxygenase (IDO) inhibitor for cancer research.</p>
    Formula:C12H14N2O2
    Purity:95.39%
    Color and Shape:Solid
    Molecular weight:218.25
  • Navoximod

    CAS:
    <p>Navoximod (GDC-0919) (NLG- 919, GDC-0919) is a potent indoleamine-(2,3)-dioxygenase (IDO) pathway inhibitor (Ki/EC50: 7 nM/75 nM).</p>
    Formula:C18H21FN2O2
    Purity:99.37%
    Color and Shape:Solid
    Molecular weight:316.37
  • IDO1-IN-1

    CAS:
    <p>IDO1-IN-1 (2 HzBTZ) is an indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor.</p>
    Formula:C7H7N3S
    Purity:99.36%
    Color and Shape:Slightly Yellow To Beige-Green Crystalline Powder
    Molecular weight:165.22
  • Indoximod

    CAS:
    <p>Indoximod (NLG-8189) is a methylated tryptophan that inhibits IDO to boost T cell function by preventing tryptophan depletion.</p>
    Formula:C12H14N2O2
    Purity:97.82% - 99.55%
    Color and Shape:Solid
    Molecular weight:218.25
  • Linrodostat mesylate

    CAS:
    <p>Linrodostat (BMS-986205) is an oral IDO1 inhibitor that boosts immune response and has anti-cancer properties.</p>
    Formula:C25H28ClFN2O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:507.02