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IDO

IDO

Indoleamine 2,3-dioxygenase (IDO) is an enzyme involved in the catabolism of tryptophan, leading to the production of kynurenine and other metabolites. IDO plays a role in immune tolerance and is often upregulated in cancer and chronic inflammatory conditions. Inhibitors of IDO are being explored as potential immunotherapeutic agents in cancer and autoimmune diseases. At CymitQuimica, we provide IDO inhibitors to support your research in immunology, oncology, and metabolic regulation.

Found 82 products of "IDO"

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  • Linrodostat
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    Linrodostat

    CAS:
    <p>Linrodostat (BMS-986205) is a selective indoleamine 2, 3-dioxygenase 1 (IDO1) inhibitor.</p>
    Formula:C24H24ClFN2O
    Purity:99.54% - 99.71%
    Color and Shape:Solid
    Molecular weight:410.91

    Ref: TM-T4532

  • IDO-IN-7
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    IDO-IN-7

    CAS:
    <p>IDO-IN-7 (NLG-919 analogue) is a potent IDO (indoleamine-(2, 3)-dioxygenase) pathway inhibitor.</p>
    Formula:C18H22N2O
    Purity:99.32% - 99.9%
    Color and Shape:Solid
    Molecular weight:282.38

    Ref: TM-T1806

  • IDO1-IN-21
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    IDO1-IN-21

    CAS:
    <p>IDO1-IN-21 (compound 10m), with an IC50 of 0.64 μM, acts as an IDO1 inhibitor and has demonstrated efficacy in suppressing tumor growth in murine models [1].</p>
    Formula:C21H19F2N3O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:479.45

    Ref: TM-T78687

  • IDO-IN-5
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    IDO-IN-5

    CAS:
    <p>IDO-IN-5 is an indoleamine 2,3-dioxygenase (IDO) inhibitor (IC50: 1-10 μM).</p>
    Formula:C18H21FN2O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:316.37

    Ref: TM-T11619

  • IDO1/TDO-IN-3
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    IDO1/TDO-IN-3

    CAS:
    <p>IDO1/TDO-IN-3 inhibits IDO1 (IC50: 0.005 μM) and TDO (IC50: 0.004 μM) with strong anti-tumor activity and low toxicity.</p>
    Formula:C16H6ClF2N3O2
    Color and Shape:Solid
    Molecular weight:345.69

    Ref: TM-T61140

  • IDO-IN-11
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    IDO-IN-11

    CAS:
    <p>IDO-IN-11 is an indoleamine-2,3-dioxygenase (IDO) inhibitor with IC50s of 0.18 μM (Kinase) and 0.014 μM (Hela Cell).</p>
    Formula:C19H23BrFN7O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:544.4

    Ref: TM-T11614

  • IACS-8968 R-enantiomer
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    IACS-8968 R-enantiomer

    CAS:
    <p>IACS-8968 R-enantiomer is the R-enantiomer of IACS-8968. IACS-8968 is a dual IDO and TDO inhibitor (pIC50s: 6.43 for IDO and &lt;5 for TDO).</p>
    Formula:C17H18F3N5O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:381.35

    Ref: TM-T11627

  • IDO-IN-4
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    IDO-IN-4

    CAS:
    <p>IDO-IN-4 is an indoleamine 2,3-dioxygenase 1 (IDO-1) inhibitor.</p>
    Formula:C26H35N3O3
    Color and Shape:Solid
    Molecular weight:437.57

    Ref: TM-T11618

  • IDO-IN-6
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    IDO-IN-6

    CAS:
    <p>IDO-IN-6 is an indoleamine 2,3-dioxygenase (IDO) inhibitor.</p>
    Formula:C18H21FN2O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:316.37

    Ref: TM-T11620

  • IDO1-IN-18
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    IDO1-IN-18

    CAS:
    <p>IDO1-IN-18 (Compound 14) is a potent inhibitor of IDO1. IDO1-IN-18 has potential for cancer disease research.</p>
    Formula:C23H18F4N2O3
    Color and Shape:Solid
    Molecular weight:446.39

    Ref: TM-T62638

  • MMG-0358
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    MMG-0358

    CAS:
    <p>MMG-0358 is a novel potent IDO1 inhibitor, showing low cytotoxicity and higher selectivity for IDO1 over TDO enzyme.</p>
    Formula:C8H6ClN3O
    Color and Shape:Solid
    Molecular weight:195.61

    Ref: TM-T71954

  • IDO-IN-16
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    IDO-IN-16

    CAS:
    <p>IDO-IN-16 (compound 5) is an IDO inhibitor (IC50: 36 nM).</p>
    Formula:C22H21F3N4O
    Color and Shape:Solid
    Molecular weight:414.42

    Ref: TM-T62130

  • IDO/TDO-IN-1
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    IDO/TDO-IN-1

    CAS:
    <p>IDO/TDO-IN-1 is an orally active dual indoleamine-2,3-dioxygenase (IDO) and tryptophan 2,3-dioxygenase (TDO) inhibitor (IC50s: 9.7 and 47 nM).</p>
    Formula:C25H24FN5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:413.49

    Ref: TM-T11623

  • IDO1/TDO-IN-2
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    IDO1/TDO-IN-2

    CAS:
    <p>IDO1/TDO-IN-2: IDO1/TDO inhibitor; IC50s: IDO1, 0.1μM; TDO, 0.07μM; potential for cancer research.</p>
    Formula:C16H9N3O2
    Color and Shape:Solid
    Molecular weight:275.26

    Ref: TM-T60499

  • IDO1-IN-16
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    IDO1-IN-16

    CAS:
    <p>IDO1-IN-16 (I-1) is an IDO1 inhibitor that targets holo-IDO1 (IC50: 127 nM).</p>
    Formula:C25H35BrFN5O2
    Color and Shape:Solid
    Molecular weight:536.48

    Ref: TM-T63780

  • IDO1-IN-15
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    IDO1-IN-15

    CAS:
    <p>IDO1-IN-15 is an effective IDO1 inhibitor with IC50 of 127 nM. The potency of IDO1-IN-15 against IDO1 enzyme is comparable with Epacadostat in vitro.</p>
    Formula:C13H14BrFN6O3
    Color and Shape:Solid
    Molecular weight:401.19

    Ref: TM-T61944

  • DP00477
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    DP00477

    CAS:
    <p>DP00477, a potent inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), exhibits an inhibitory concentration (IC50) of 7.0 µM.</p>
    Formula:C17H11ClF3N3OS
    Color and Shape:Solid
    Molecular weight:397.8

    Ref: TM-T73437

  • IDO1-IN-17
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    IDO1-IN-17

    CAS:
    <p>IDO1-IN-17 (I-4) is an IDO1 inhibitor, with an IC 50 of 0.44 μM in hela cells .</p>
    Formula:C28H32BrClFN5O2
    Color and Shape:Solid
    Molecular weight:604.94

    Ref: TM-T73111

  • IDO-IN-14
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    IDO-IN-14

    CAS:
    <p>IDO-IN-14 is an IDO inhibitor (IC50: 0.6928 nM).</p>
    Formula:C23H23ClN4O2
    Color and Shape:Solid
    Molecular weight:422.91

    Ref: TM-T62270

  • Roxyl-9
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    Roxyl-9

    CAS:
    <p>Roxyl-9 is an inhibitor of IDO1 (Indoleamine 2,3-dioxygenase 1) [1].</p>
    Formula:C18H13N3O2
    Color and Shape:Solid
    Molecular weight:303.31

    Ref: TM-T60698