IDO
Indoleamine 2,3-dioxygenase (IDO) is an enzyme involved in the catabolism of tryptophan, leading to the production of kynurenine and other metabolites. IDO plays a role in immune tolerance and is often upregulated in cancer and chronic inflammatory conditions. Inhibitors of IDO are being explored as potential immunotherapeutic agents in cancer and autoimmune diseases. At CymitQuimica, we provide IDO inhibitors to support your research in immunology, oncology, and metabolic regulation.
Found 86 products for "IDO".
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
(S)-Indoximod
CAS:(S)-Indoximod (L-Abrine) is an indoleamine-2,3-dioxygenase (IDO) inhibitor for cancer research.Formula:C12H14N2O2Purity:95.39% - 99.69%Color and Shape:White SolidMolecular weight:218.25Epacadostat
CAS:Epacadostat (INCB 024360) is an oral, potent and selective IDO1 inhibitor with IC50 value of 71.8 nM.Cost-effective and quality-assured.Formula:C11H13BrFN7O4SPurity:98% - >99.99%Color and Shape:SolidMolecular weight:438.23Ref: TM-T3548
5mg44.00€1mL*10mM (DMSO)48.00€10mg66.00€25mg93.00€50mg105.00€100mg177.00€200mg295.00€500mg497.00€1g717.00€2g982.00€IDO-IN-1
CAS:IDO-IN-1: potent IDO inhibitor, IC50 of 59 nM (enzyme), 12 nM (HeLa cells).Formula:C9H7BrFN5O2Purity:99.91%Color and Shape:SolidMolecular weight:316.09Ref: TM-T7181
1mg49.00€5mg96.00€1mL*10mM (DMSO)110.00€10mg155.00€25mg269.00€50mg404.00€100mg567.00€200mg763.00€PF-06840003
CAS:PF-06840003 (EOS200271) is a specific and oral active IDO-1 inhibitor.Formula:C12H9FN2O2Purity:99.10%Color and Shape:SolidMolecular weight:232.21Ref: TM-T4307
2mg34.00€5mg50.00€1mL*10mM (DMSO)55.00€10mg88.00€25mg102.00€50mg120.00€100mg178.00€200mg268.00€Navoximod
CAS:Navoximod (GDC-0919) (NLG- 919, GDC-0919) is a potent indoleamine-(2,3)-dioxygenase (IDO) pathway inhibitor (Ki/EC50: 7 nM/75 nM).Formula:C18H21FN2O2Purity:99.37%Color and Shape:White SolidMolecular weight:316.37Ref: TM-TQ0071
1mg150.00€5mg313.00€1mL*10mM (DMSO)318.00€10mg470.00€25mg600.00€50mg745.00€100mg1,044.00€BMS-986242
CAS:BMS-986242 is an orally active, potent and selective inhibitor of indoleamine-2,3-dioxygenase 1 (IDO1), and it can be used for the research of cancer.Formula:C24H24ClFN2OPurity:98.9%Color and Shape:White SolidMolecular weight:410.91IDO-IN-11
CAS:IDO-IN-11 is an indoleamine-2,3-dioxygenase (IDO) inhibitor with IC50s of 0.18 μM (Kinase) and 0.014 μM (Hela Cell).Formula:C19H23BrFN7O4SPurity:98%Color and Shape:SolidMolecular weight:544.4IDO-IN-5
CAS:IDO-IN-5 is an indoleamine 2,3-dioxygenase (IDO) inhibitor (IC50: 1-10 μM).Formula:C18H21FN2O2Purity:98%Color and Shape:SolidMolecular weight:316.37IDO1/TDO-IN-3
CAS:IDO1/TDO-IN-3 inhibits IDO1 (IC50: 0.005 μM) and TDO (IC50: 0.004 μM) with strong anti-tumor activity and low toxicity.Formula:C16H6ClF2N3O2Color and Shape:SolidMolecular weight:345.69IACS-8968 R-enantiomer
CAS:IACS-8968 R-enantiomer is the R-enantiomer of IACS-8968. IACS-8968 is a dual IDO and TDO inhibitor (pIC50s: 6.43 for IDO and <5 for TDO).Formula:C17H18F3N5O2Purity:98%Color and Shape:SolidMolecular weight:381.35IDO-IN-4
CAS:IDO-IN-4 is an indoleamine 2,3-dioxygenase 1 (IDO-1) inhibitor.Formula:C26H35N3O3Color and Shape:SolidMolecular weight:437.57IDO-IN-6
CAS:IDO-IN-6 is an indoleamine 2,3-dioxygenase (IDO) inhibitor.Formula:C18H21FN2O2Purity:98%Color and Shape:SolidMolecular weight:316.37IDO1-IN-18
CAS:IDO1-IN-18 (Compound 14) is a potent inhibitor of IDO1. IDO1-IN-18 has potential for cancer disease research.Formula:C23H18F4N2O3Color and Shape:SolidMolecular weight:446.39MMG-0358
CAS:MMG-0358 is a novel potent IDO1 inhibitor, showing low cytotoxicity and higher selectivity for IDO1 over TDO enzyme.Formula:C8H6ClN3OColor and Shape:SolidMolecular weight:195.61IDO-IN-16
CAS:IDO-IN-16 (compound 5) is an IDO inhibitor (IC50: 36 nM).Formula:C22H21F3N4OColor and Shape:SolidMolecular weight:414.42IDO/TDO-IN-1
CAS:IDO/TDO-IN-1 is an orally active dual indoleamine-2,3-dioxygenase (IDO) and tryptophan 2,3-dioxygenase (TDO) inhibitor (IC50s: 9.7 and 47 nM).Formula:C25H24FN5Purity:98%Color and Shape:SolidMolecular weight:413.49IDO1/TDO-IN-2
CAS:IDO1/TDO-IN-2: IDO1/TDO inhibitor; IC50s: IDO1, 0.1μM; TDO, 0.07μM; potential for cancer research.Formula:C16H9N3O2Color and Shape:SolidMolecular weight:275.26IDO1-IN-16
CAS:IDO1-IN-16 (I-1) is an IDO1 inhibitor that targets holo-IDO1 (IC50: 127 nM).Formula:C25H35BrFN5O2Color and Shape:SolidMolecular weight:536.48IDO1-IN-15
CAS:IDO1-IN-15 is an effective IDO1 inhibitor with IC50 of 127 nM. The potency of IDO1-IN-15 against IDO1 enzyme is comparable with Epacadostat in vitro.Formula:C13H14BrFN6O3Color and Shape:SolidMolecular weight:401.19DP00477
CAS:DP00477, a potent inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), exhibits an inhibitory concentration (IC50) of 7.0 µM.Formula:C17H11ClF3N3OSColor and Shape:SolidMolecular weight:397.8
