Carbonic Anhydrase
Carbonic anhydrase is an enzyme that catalyzes the reversible conversion of carbon dioxide and water into bicarbonate and protons. This enzyme plays a crucial role in maintaining acid-base balance, respiration, and the transport of carbon dioxide in the blood. Inhibitors of carbonic anhydrase are used in the treatment of glaucoma, epilepsy, and altitude sickness, as well as in research on acid-base homeostasis and gas exchange. At CymitQuimica, we offer a range of high-quality carbonic anhydrase inhibitors and reagents to support your research in enzymology, respiratory physiology, and therapeutic development.
Found 221 products for "Carbonic Anhydrase".
Filter by
Purity percentage
0
100
|
0
|
50
|
90
|
95
|
100
- Lower prices
- Higher prices
- Lower purities
- Higher purities
- Faster estimated delivery
Acipimox
CAS:Acipimox (K-9321), a niacin derivative, treats hyperlipidemia in type 2 diabetics.Formula:C6H6N2O3Purity:98.98% - 99.71%Color and Shape:SolidMolecular weight:154.1234Benzthiazide
CAS:Benzthiazide treats edema and hypertension by promoting diuresis and inhibiting kidney Na+/Cl- reuptake, but may reduce potassium and raise uric acid.Formula:C15H14ClN3O4S3Purity:98.48% - 99.79%Color and Shape:White SolidMolecular weight:431.937Hydrochlorothiazide
CAS:Hydrochlorothiazide (HCTZ) 是一种口服有效的噻嗪类的利尿药，可抑制转化 TGF-β/Smad 信号通路。它通过打开钙激活钾 (KCA) 通道发挥直接的血管松弛作用。它改善心脏功能，减少纤维化并具有降压作用。Formula:C7H8ClN3O4S2Purity:99.43% - 99.50%Color and Shape:White SolidMolecular weight:297.739Methazolamide
CAS:Methazolamide (CL 8490) is a carbonic anhydrase inhibitor that is used as a diuretic and in the treatment of glaucoma.Formula:C5H8N4O3S2Purity:99.31% - 99.77%Color and Shape:SolidMolecular weight:236.27Actarit
CAS:Actarit (4-acetylaminophenylacetic acid) is an anti-inflammatory drug.Formula:C10H11NO3Purity:99.64% - 99.74%Color and Shape:White Or Off-White Crystal Or Crystalline SolidMolecular weight:193.1992Brinzolamide
CAS:Brinzolamide (AL-4862) is a Carbonic Anhydrase Inhibitor. The mechanism of action of brinzolamide is as a Carbonic Anhydrase Inhibitor.Formula:C12H21N3O5S3Purity:99.84% - >99.99%Color and Shape:SolidMolecular weight:383.51Girentuximab
CAS:Girentuximab (G250) is an anti-carbonic anhydrase IX (CAIX) monoclonal antibody with anti-cancer activity for the study of uroepithelial carcinoma PET (ZiPUP).Color and Shape:Transparent LiquidMolecular weight:145.55 kDa (Predicted)Methocarbamol
CAS:Methocarbamol (AHR 85) is a centrally acting muscle relaxant whose mode of action has not been established.Formula:C11H15NO5Purity:99.96%Color and Shape:White SolidMolecular weight:241.2405Zonisamide
CAS:Zonisamide (AD 810), a sulfonamide anticonvulsant, is approved for use as an adjunctive treatment in adults with partial-onset seizures.Formula:C8H8N2O3SPurity:99.05% - 99.9%Color and Shape:SolidMolecular weight:212.226Topiramate
CAS:Topiramate (RWJ 17021) is a unique antiseizure medication that is used in the treatment of partial and generalized seizures.Formula:C12H21NO8SPurity:99.79% - 99.92%Color and Shape:SolidMolecular weight:339.36CAIX Inhibitor S4
CAS:CAIX Inhibitor S4 (S4) is an effective inhibitor of carbonic anhydrase IX/XII with a Ki of 7 nM and 2 nM, respectively.Formula:C15H17N3O4SPurity:99.07%Color and Shape:SolidMolecular weight:335.38Tioxolone
CAS:Tioxolone is a metalloenzyme carbonic anhydrase I inhibitor.Formula:C7H4O3SPurity:97.79%Color and Shape:White SolidMolecular weight:168.17pNNP
CAS:pNNP is a substrate for PP2C assays and inhibits β-carbonic anhydrase, α-carbonate dehydrogenase, and H. pylori.Formula:C6H6NO6PPurity:99.82%Color and Shape:White SolidMolecular weight:219.09hCA-IN-1
hCA-IN-1 (Compound 5u) is an hCA inhibitor with Ki values of 159.2 nM for hCA I, 4.8 nM for hCA II, 15.5 nM for CAIX, and 2 nM for CAXII. It demonstrates broad-spectrum anticancer activity against melanoma, breast cancer, and colon cancer cells. ADME predictions indicate that hCA-IN-1 has good solubility and oral bioavailability. This compound is useful in tumor research.Carbonic anhydrase-IN-37
Carbonic anhydrase-IN-37 (compound 9a) is a potent and orally active inhibitor of carbonic anhydrase (CA), exhibiting Ki values of 9.7 nM for hCA VA and 1.0 nM for hCA VB. It demonstrates anti-hyperalgesic and anti-allodynic properties in a mouse model of paclitaxel-induced neuropathic pain, making it useful for neuropathic pain research.hCAIX-IN-22
hCAIX-IN-22 is a highly selective inhibitor of the human carbonic anhydrase (hCA) XII subtype, exhibiting anticancer activity with an inhibition constant (Ki) of 9.7 nM.DOTA-XYIMSR-01
CAS:DOTA-XYIMSR-01 is a molecular probe targeting CAIX, capable of being labeled with 177Lu for the treatment and localization of malignant gliomas. The uptake of [177Lu]Lu-XYIMSR-01 in U87MG tumors is 6.19% injected dose per gram (% ID/g), with a tumor-to-muscle uptake ratio of 20.14. In an orthotopic glioma model, co-administration with temozolomide significantly enhances survival rates and inhibits tumor growth in mice. DOTA-XYIMSR-01 shows potential for research in the field of cancer treatment.Formula:C61H88N16O22S2Color and Shape:SolidMolecular weight:1461.57IPM-N001
IPM-N001 is a ligand for carbonic anhydrase IX (CAIX) with a Kd value of less than 0.0337 nM for hCAIX. When radiolabeled with 68Ga, it serves as a CAIX-targeting radionuclide tracer. [68Ga]Ga-IPM-N001 demonstrates excellent tumor uptake and significantly enhances the tumor-to-background ratio in PET/CT imaging studies using OS-RC-2 tumor-bearing mice. IPM-N001 is applicable for research on clear cell renal cell carcinoma.CA IX-IN-5
CAIX-IN-5 (compound 9) is an inhibitor of human carbonic anhydrase IX (hCA IX), exhibiting a Ki of 7.4 nM for hCA IX and a Ki of 25.0 nM for hCA II. It effectively inhibits the isoenzymes hCA IX and hCA II, showing higher selectivity for hCA IX than hCA II. CAIX-IN-5 is used in research related to breast cancer, colorectal cancer, glioblastoma, lung cancer, head and neck cancer, and cervical cancer.CAIX/CAXII-IN-2
CAIX/CAXII-IN-2 (compound 23) is a CAIX/CAXII inhibitor, exhibiting Ki values of 8.9 nM for CAIX and 5.3 nM for CAXII. It is applicable in cancer research.Formula:C16H14N4O2SMolecular weight:326.08375
