PPAR
Peroxisome Proliferator-Activated Receptors (PPARs) are a group of nuclear receptor proteins that function as transcription factors regulating the expression of genes involved in metabolism, particularly fatty acid storage and glucose metabolism. PPAR inhibitors are important tools for studying metabolic disorders such as diabetes, obesity, and cardiovascular diseases. These inhibitors can modulate lipid metabolism, insulin sensitivity, and inflammation, making them valuable in therapeutic research. At CymitQuimica, we offer a range of PPAR inhibitors to support your research in metabolic diseases, endocrinology, and drug development.
Found 170 products of "PPAR"
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Licarin B
CAS:1.(-)-Licarin B (Licarine B) has anti-mycobacterial activity.Formula:C20H20O4Purity:99.82% - ≥95%Color and Shape:SolidMolecular weight:324.37Norathyriol
CAS:Norathyriol is a potent PTP1B inhibitor with good cell permeability and oral availability.Formula:C13H8O6Purity:99.35% - 99.55%Color and Shape:SolidMolecular weight:260.2Ref: TM-TN1990
1mg141.00€5mg335.00€10mg500.00€25mg807.00€50mg1,099.00€100mg1,485.00€200mg1,998.00€1mL*10mM (DMSO)447.00€Eupatilin
CAS:Eupatilin (NSC-122413), a flavone derived from Artemisia princepsPampanini, is a PPARα agonist, with pharmacological activity.Formula:C18H16O7Purity:98.53% - 99%Color and Shape:SolidMolecular weight:344.32Troglitazone
CAS:Troglitazone (Romglizone) is a PPARγ agonist with anti-inflammatory and anti-tumor activity.Formula:C24H27NO5SPurity:98% - 99.8%Color and Shape:Yellow SolidMolecular weight:441.54Ref: TM-T3170
2mg42.00€5mg62.00€10mg88.00€25mg172.00€50mg305.00€100mg558.00€500mg1,169.00€1mL*10mM (DMSO)85.00€DG172 dihydrochloride
CAS:DG172 dihydrochloride (DG-172 dihydrochloride) is an antagonist of PPARβ/δ(IC50 : 27 nM).
Formula:C20H22BrCl2N3Purity:99.87%Color and Shape:SolidMolecular weight:455.2Tetradecylthioacetic acid
CAS:Synthetic fatty acid TTA has β-sulfur, resists β-oxidation, and activates PPARs, especially PPARα.
Formula:C16H32O2SPurity:99.93%Color and Shape:SolidMolecular weight:288.49T0070907
CAS:T0070907(IC50=1 nM) , an effective and specific PPARγ inhibitor, with the >800-fold selectivity over PPARα and PPARδ.
Formula:C12H8ClN3O3Purity:98.25% - 99.98%Color and Shape:SolidMolecular weight:277.66Seladelpar
CAS:Seladelpar (MBX 8025) has been used in trials studying the treatment of Hyperlipidemia.Formula:C21H23F3O5SPurity:99.18% - 99.41%Color and Shape:SolidMolecular weight:444.46Rosiglitazone
CAS:Rosiglitazone (BRL49653) is a PPARγ agonist, TRPC5 activator, and TRPM3 inhibitor with oral activity.Formula:C18H19N3O3SPurity:98.61% - 99.87%Color and Shape:White To Off-White Crystalline PowderMolecular weight:357.43GW9662
CAS:GW9662 (TIMTEC-BB SBB006523) is a PPARγ antagonist (IC50=3.3 nM) with selectivity. GW9662 has anti-tumor effect. High-Quality, Low-Cost!Formula:C13H9ClN2O3Purity:98% - 99.98%Color and Shape:Off-White SolidMolecular weight:276.68SR1664
CAS:SR1664 is a potent and selective PPARγ inhibitor with potential antidiabetic activity.Formula:C33H29N3O5Purity:98.02%Color and Shape:SolidMolecular weight:547.6Ref: TM-T23389
1mg52.00€2mg74.00€5mg111.00€10mg144.00€25mg284.00€50mg411.00€100mg590.00€200mg833.00€1mL*10mM (DMSO)123.00€FH535
CAS:FH535, a Wnt/β-catenin signaling and PPAR inhibitor, exhibits anti-tumor activities.Formula:C13H10Cl2N2O4SPurity:98.25% - 99.5%Color and Shape:SolidMolecular weight:361.2Ref: TM-T2413
5mg35.00€10mg54.00€25mg88.00€50mg156.00€100mg259.00€200mg383.00€500mg620.00€1mL*10mM (DMSO)60.00€Icariin
CAS:Icariin (Ieariline) is a flavonol glycoside that inhibits PDE5 and PDE4 activity and is a PPARα activator. Cost-effective and quality-assured.Formula:C33H40O15Purity:97.82% - 98.3%Color and Shape:SolidMolecular weight:676.66GW6471
CAS:GW6471 is an antagonist of PPARα. GW6471 enhances the binding affinity of the PPAR α ligand-binding domain to the co-repressor proteins SMRT and NCoR.Formula:C35H36F3N3O4Purity:98.23% - 99.55%Color and Shape:SolidMolecular weight:619.67Ref: TM-T8486
2mg35.00€5mg52.00€10mg88.00€25mg177.00€50mg311.00€100mg533.00€200mg802.00€1mL*10mM (DMSO)87.00€Palmitelaidic Acid
CAS:Palmitelaidic Acid (trans-Palmitoleic acid) is one of the most abundant fatty acids in serum and tissue.Formula:C16H30O2Purity:99.76%Color and Shape:SolidMolecular weight:254.41NSC-87877 disodium
CAS:NSC-87877 disodium (NSC87877) is a cell-permeable inhibitor of both SHP-1 and SHP-2. NSC-87877 also inhibits EGF-induced Erk1/2 activation in HEK293 cells.Formula:C19H13N3O7S2·2NaPurity:97.89%Color and Shape:SolidMolecular weight:503.42Glabrone
CAS:Glabrone shows antiviral activity against influenza virus.Formula:C20H16O5Purity:99.08% - 99.55%Color and Shape:SolidMolecular weight:336.34Tesaglitazar
CAS:Tesaglitazar is a potent and selective peroxide PPARα / γ receptor dual agonist with a more potent affinity for PPARγ than PPARα, The EC50 values for rat PPARαFormula:C20H24O7SPurity:99.95%Color and Shape:SolidMolecular weight:408.47Ref: TM-T17044
1mg46.00€5mg87.00€10mg137.00€25mg255.00€50mg427.00€100mg667.00€200mg924.00€1mL*10mM (DMSO)97.00€THR-0921
CAS:THR-0921 (CLX-0921) is a peroxisome proliferator-activated receptor (PPAR) agonist that can be used to study cardiovascular and metabolic diseases.Formula:C28H25NO7SPurity:100% - 99.83%Color and Shape:SolidMolecular weight:519.5713-Oxo-9E,11E-octadecadienoic acid
CAS:13-Oxo-9E,11E-octadecadienoic acid from tomato juice, an isomer of 9-oxo-ODA, activates PPARα and lowers triglycerides in diabetic mice.Formula:C18H30O3Purity:98%Color and Shape:SolidMolecular weight:294.43AVE-8134
CAS:AVE-8134 is an agonist of PPARα. For human and rodent PPARα receptor, the EC50 values are 100 and 3000 nM, respectively.Formula:C22H23NO5Purity:98%Color and Shape:SolidMolecular weight:381.42GW 9578
CAS:GW 9578 is a PPARα agonist with potent lipid-lowering activity for the study of psoriasis, arthritis, alopecia, asthma and type I diabetes.Formula:C26H34F2N2O3SPurity:98%Color and Shape:SolidMolecular weight:492.62Peliglitazar racemate
CAS:Peliglitazar racemate(BMS 426707-01 racemate) is the racemate of Peliglitazar.Peliglitazar racemate may be used as a potential antidiabetic and anti-obesityFormula:C30H30N2O7Purity:97.75%Color and Shape:SolidMolecular weight:530.57BVT.13
CAS:BVT.13 is an orally active selective PPARγ agonist with antidiabetic activity comparable to rosiglitazone, supporting research in metabolic regulation.Formula:C18H11Cl2N3O4Purity:98.59%Color and Shape:SolidMolecular weight:404.2FTX-6746
CAS:FTX-6746 is an orally active and selective PPARG reverse inhibitor with anticancer activity. It can be used in research on urothelial carcinoma.Formula:C16H7ClF2N2OPurity:98.68%Color and Shape:SolidMolecular weight:316.69GSK376501A
CAS:GSK376501A is a selective and effective modulator of peroxisome proliferator-activated receptor γ (PPARγ) for the study of type 2 diabetes.Formula:C32H37NO6Purity:97.71% - >99.99%Color and Shape:SolidMolecular weight:531.64Pparδ agonist 2
CAS:Pparδ agonist 2 is an agonist of PPARδ.Formula:C20H18F3N3O3SPurity:98%Color and Shape:SolidMolecular weight:437.44Daltroban
CAS:Daltroban (SKF 96148) is a specific thromboxane A2 (TXA2) receptor antagonist.Formula:C16H16ClNO4SPurity:99.74%Color and Shape:SolidMolecular weight:353.82Ref: TM-T15049
1mg55.00€5mg122.00€10mg177.00€25mg295.00€50mg420.00€100mg572.00€200mg772.00€1mL*10mM (DMSO)111.00€Saroglitazar
CAS:Saroglitazar (Lipaglyn) is an agonist of PPAR with EC50 values of 0.65 pM and 3 nM for PPARα and PPARγ.Formula:C25H29NO4SPurity:98.51%Color and Shape:SolidMolecular weight:439.57PPARα-MO-1
CAS:PPARα-MO-1 is a potent modulator of PPARα.Formula:C27H37NO5Purity:98%Color and Shape:SolidMolecular weight:455.59LG100754
CAS:LG100754 (UVI 2112) is an insulin sensitizer and RXR modulator, antagonizing RXR homodimers while agonizing RXR:PPARα/γ heterodimers.Formula:C26H36O3Color and Shape:SolidMolecular weight:396.56Chiglitazar
CAS:Chiglitazar is a PPAR α/γ/δ agonist and insulin sensitizer used in the treatment of type 2 diabetes mellitus , anti-inflammatory and anti-fibrotic.Formula:C36H29FN2O4Color and Shape:SolidMolecular weight:572.63Inolitazone dihydrochloride
CAS:Inolitazone dihydrochloride is an effective, high-affinity PPARγ agonist; its biological activity is dependent on PPARγ (IC50:0.8 nM) to inhibit cell growth.Formula:C27H28Cl2N4O4SColor and Shape:SolidMolecular weight:575.51ARH-049020
CAS:ARH-049020, a peroxisome proliferator-activated receptor (PPAR) agonist, is used potentially for the treatment of insulin resistance and type 2 diabetes.Formula:C24H31NO6Purity:97.19% - 99.82%Color and Shape:SolidMolecular weight:429.51Reglitazar
CAS:Reglitazar, a dual PPARα/γ agonist, enhances insulin signaling, reduces insulin resistance, and lowers hypertriglyceridemia in obese rats.Formula:C22H20N2O5Purity:97.07% - 98.72%Color and Shape:SolidMolecular weight:392.4BAY-0069
CAS:BAY-0069 is a potent and selective PPARγ transactivator that inhibits human PPARγ and murine PPARγ with IC50s of 6.3 nM and 24 nM, respectively.BAY-0069 can be
Formula:C22H16BrN3O4Purity:99.41%Color and Shape:SoildMolecular weight:466.28Indeglitazar
CAS:Indeglitazar (PPM 204) is orally available pan-agonist of PPAR (PPAR subtypes alpha (α), delta (δ), and gamma (γ)).Formula:C19H19NO6SPurity:99.45%Color and Shape:SolidMolecular weight:389.42Farglitazar
CAS:Farglitazar (GI-262570) is a PPAR-γ agonist and insulin sensitizer used in the study of diabetes.Formula:C34H30N2O5Purity:99.4% - 99.52%Color and Shape:SolidMolecular weight:546.61Dazmegrel
CAS:Dazmegrel (UK 38,485) is a thromboxane A2 (TXA2) synthase inhibitor for the prevention of increased whole platelet aggregation in normal pregnancy.Formula:C16H17N3O2Purity:98.81%Color and Shape:SolidMolecular weight:283.33Cevoglitazar
CAS:Cevoglitazar (LBM-642) is a PPARɑ agonist and PPARγ agonist. Cevoglitazar potently reduces food intake and body weight in obese mice and cynomolgus monkeys.Formula:C27H21F3N2O6SPurity:97%Color and Shape:SolidMolecular weight:558.53K-111
CAS:K-111 is a PPAR alpha agonist. K-111 improves insulin resistance, reducing bodyweight, and ameliorating atherogenic dyslipidemia.Formula:C18H25Cl3O2Purity:99.64% - 99.88%Color and Shape:SolidMolecular weight:379.75BAY-4931
CAS:BAY-4931 is a powerful, covalent, and selective inverse-agonist of PPARγ, exhibiting an IC50 value of 0.17 nM.Formula:C22H16ClN3O4Purity:99.73%Color and Shape:SoildMolecular weight:421.83Ref: TM-T67933
1mg38.00€5mg84.00€10mg119.00€25mg260.00€50mg409.00€100mg605.00€500mg1,288.00€1mL*10mM (DMSO)93.00€Linotroban
CAS:Linotroban（CL-871502） is a potent selective thromboxane (TXA2) receptor antagonist with antithrombotic activity.Formula:C14H15NO5S2Purity:97.95% - >99.99%Color and Shape:SolidMolecular weight:341.4Imiglitazar
CAS:Imiglitazar (TAK559) is a potent PPAR-β/δ receptor agonist with hypoglycemic effects.Formula:C28H26N2O5Purity:97.33%Color and Shape:SolidMolecular weight:470.52Darglitazone
CAS:Darglitazone (CP-86325) is a potent, selective agonist of PPAR-γ with antidiabetic actions.Formula:C23H20N2O4SPurity:99.76%Color and Shape:SolidMolecular weight:420.48LCB-2853
CAS:LCB-2853 is a potent thromboxane A2/prostaglandin H2 (TXA2/PGH2) receptor antagonist with antiplatelet aggregation, antivasospasm, and antithrombotic effects.Formula:C21H24ClNO4SPurity:97.15%Color and Shape:SolidMolecular weight:421.94KD-3010
CAS:KD-3010 (Kalypsys) is an orally active potent and selective PPARδ agonist for the study of liver injury.Formula:C30H33F3N2O8S2Purity:99.61%Color and Shape:SolidMolecular weight:670.72PPARγ agonist 8
CAS:PPARγ agonist 8, a compound that acts on the peroxisome proliferator-activated receptor gamma (PPARγ), has been shown to stimulate peroxisome proliferatorFormula:C19H12F4O2SPurity:98%Color and Shape:SolidMolecular weight:380.36U-46619
CAS:U-46619 is an effective thromboxane A2 (TXA2) agonist and a thromboxane A2 analog (endoperoxide), capable of inducing contraction in the aortic smooth muscle (Formula:C21H34O4Purity:98%Color and Shape:SolidMolecular weight:350.49PPARδ agonist 9
CAS:PPARδ agonist 9 (compound 21), with an EC50 of 3.6 nM, is effective in vivo, decreasing serum MCP-1 concentrations in mice and markedly reducing atheroscleroticFormula:C26H28ClF3N4O3SPurity:98%Color and Shape:SolidMolecular weight:569.04PPAR agonist 1
CAS:PPAR agonist 1 is an agonist of PPAR α/γ, used for reducing blood glucose, lipid levels, reducing body weight, and lowering cholesterol.Formula:C20H25NO6SPurity:98%Color and Shape:SolidMolecular weight:407.48CRX000227
CAS:CRX000227 is a PPAR modulator suitable for researching metabolic and cell proliferative disorders [1].Formula:C25H24N4O2SPurity:98%Color and Shape:SolidMolecular weight:444.55Edaglitazone
CAS:Edaglitazone (R-483) is a PPARγ agonist with antiplatelet activity that can be used in studies of diabetes and obesity.Formula:C24H20N2O4S2Purity:98%Color and Shape:SolidMolecular weight:464.56Inolitazone
CAS:Inolitazone (RS5444) a high-affinity PPARγ agonist. Inolitazone exhibits IC50 for growth inhibition is ~0.8 nM in vitro.Formula:C27H26N4O4SPurity:99.41% - 99.53%Color and Shape:SolidMolecular weight:502.58Ref: TM-T15581
1mg70.00€5mg149.00€10mg230.00€25mg374.00€50mg532.00€100mg713.00€500mgTo inquire1mL*10mM (DMSO)178.00€Ragaglitazar
CAS:Ragaglitazar(NNC-61-0029) is a potent dual activator of PPARγ and PPARα.Cost-effective and quality-assured.Formula:C25H25NO5Purity:97.46% - 98.56%Color and Shape:SolidMolecular weight:419.47PPARγ phosphorylation inhibitor 1
CAS:PPARγ phosphorylation inhibitor 1, PPARγ agonist (IC50=24 nM), inhibits CDK5-mediated Ser273 phosphorylation, antidiabetic activity.Formula:C22H14Cl2N2O4Purity:99.86%Color and Shape:SolidMolecular weight:441.26SR 11023
CAS:SR 11023, an orally active PPAR γ antagonist, exhibits an IC 50 value of 109 nM and is significant in diabetes research [1].Formula:C33H36N2O3Color and Shape:SolidMolecular weight:508.65Anti-NASH agent 2
CAS:Anti-NASH agent 2 (compound 21) is an inhibitor of neolipogenesis activity and α-SMA gene expression. It improves hepatic steatosis, edema, inflammatory infiltration, and liver fibrosis in NASH mouse models.
Formula:C32H51N3O2Color and Shape:SolidMolecular weight:509.766PPARγ agonist 17
CAS:PPARγ agonist17 (Compound C1) is an orally active PPARγ agonist. It enhances PPARγ activity, arrests the cell cycle of HT-29 cells at the G2/M phase, inhibits cell migration, and induces apoptosis. PPARγ agonist17 exhibits broad-spectrum antiproliferative activity against cancer cells with relatively low toxicity to normal cells and does not cross the blood-brain barrier.Formula:C48H63NO7Color and Shape:SolidMolecular weight:766.016PPARγ modulator-2
CAS:PPARγmodulator-2 (Compound (R)-2n) is a reversible modulator of PPARγ, inhibiting the PPARγ ligand-binding domain (LBD) with an IC50 of 41 nM. It helps lower blood glucose levels, improves glucose tolerance and insulin sensitivity, and demonstrates antidiabetic activity in db/db mouse models.Formula:C26H21NO7S3SeColor and Shape:SolidMolecular weight:634.6Amezalpat
CAS:Amezalpat is a PPARα antagonist with an IC50 of 58 nM [nanomolar]. Amezalpat also exhibits antitumor activity.Formula:C34H41N3O4Color and Shape:SolidMolecular weight:555.707PPARγ-IN-5
CAS:PPARγ-IN-5 (Compound A3) is an inhibitor of PPARγ. In liver cells, it reduces lipid accumulation and shows no significant cytotoxicity in HepG2 cells at a concentration of 400 µM. PPARγ-IN-5 is applicable for research on non-alcoholic fatty liver disease.Formula:C22H23ClO7Color and Shape:SolidMolecular weight:434.867PPARα/δ agonist 3
CAS:PPARα/δ agonist 3 (Compound 8) is an orally active PPAR agonist capable of activating PPARα, PPARδ, and PPARγ, with EC50 values of 5.6 nM, 3.4 nM, and 1278 nM, respectively. It exhibits anti-cholestatic activity in mouse models of cholestatic liver disease induced by ANIT or CDCA.Formula:C23H25F3N2O4Color and Shape:SolidMolecular weight:450.451PPARδ agonist 11
CAS:Compound 11, a selective PPARδ agonist, demonstrates an EC50 of 20 nM, indicating its high affinity for PPARδ receptors. This compound efficiently reduces levels of nitric oxide (NO), as well as the pro-inflammatory cytokines TNFα and IL-6 in LPS-stimulated RAW264.7 cells via the NF-κB pathway, showcasing its anti-inflammatory properties. Additionally, Compound 11 exhibits remarkable stability in human liver microsomes and plasma. It significantly ameliorates foot edema induced by Carrageenan, displaying favorable pharmacokinetic properties with a bioavailability of approximately 100%.Formula:C19H15F3N2O3S2Color and Shape:SolidMolecular weight:440.46Fonadelpar
CAS:Fonadelpar is an agonist of PPARδ. It also is used in the research of neuroparalytic keratopathy.Formula:C25H23F3N2O4SPurity:98%Color and Shape:SolidMolecular weight:504.52PPARγ agonist 10
CAS:PPARγ agonist 10 (compound 33g) serves as a PPARγ agonist, enhancing insulin secretion, glucose uptake, and insulin sensitivity in βTC6 cells [1].Formula:C17H14N4O3S2Color and Shape:SolidMolecular weight:386.45Aleglitazar
CAS:Aleglitazar (R1439) (R1439) is a potent dual PPARα/γ agonist, with IC50s of 38 nM and 19 nM for human PPARa and PPARγ, respectively.Formula:C24H23NO5SPurity:99.03%Color and Shape:SolidMolecular weight:437.51Ref: TM-T14176
1mg233.00€5mg532.00€10mg718.00€25mg1,099.00€50mg1,485.00€100mg1,998.00€1mL*10mM (DMSO)538.00€PPARγ-IN-2
CAS:"PPARγ-IN-2 (Compound 5a), a PPARγ inhibitor, exhibits an EC50 of 0.106 μM in inhibiting TG accumulation in 3T3-L1 preadipocytes.
Formula:C19H21N5OPurity:98%Color and Shape:SolidMolecular weight:335.4Mavodelpar free base
CAS:Mavodelpar free acid (REN001 free acid) is an selective agonist of PPARδ.
Formula:C31H30FNO5Purity:98%Color and Shape:SolidMolecular weight:515.57Anti-NASH agent 1
CAS:Anti-NASH Agent 1 (Compound 3d), derived from Elafibranor, serves as a strong PPAR-α/δ agonist aimed at treating nonalcoholic steatohepatitis (NASH).
Formula:C26H33NO4Purity:98%Color and Shape:SolidMolecular weight:423.54
