FXR
Farnesoid X Receptor (FXR) is a nuclear receptor that plays a key role in the regulation of bile acid homeostasis, lipid metabolism, and glucose regulation. FXR is a potential therapeutic target for treating liver diseases, metabolic disorders, and cardiovascular diseases. FXR inhibitors can modulate these pathways, offering insights into disease mechanisms and therapeutic strategies. At CymitQuimica, we provide a range of FXR inhibitors to support your research in hepatology, metabolism, and drug development.
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Ursodeoxycholic acid sodium
CAS:2898-95-5
Ursodeoxycholic acid sodium (Sodium Ursodeoxycholate) is a naturally occurring secondary bile acid with anti-inflammatory and …
Formula:
C24H40NaO4
Purity:
98% - 98.55%
Color and Shape:
Solid
Molecular weight:
415.56
Ref: TM-T29078
| 50mg | 36.00 € | ||
| 100mg | 49.00 € | ||
| 500mg | 111.00 € | ||
| 1mL*10mM (DMSO) | 47.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
GW 4064
CAS:278779-30-9
GW 4064 is an effective farnesoid X receptor (FXR) agonist (EC50 =65 nM).
Formula:
C28H22Cl3NO4
Purity:
97.47% - 99.94%
Color and Shape:
Solid
Molecular weight:
542.84
Ref: TM-T2233
| 5mg | 50.00 € | ||
| 10mg | 82.00 € | ||
| 25mg | 138.00 € | ||
| 50mg | 231.00 € | ||
| 100mg | 415.00 € | ||
| 200mg | 625.00 € | ||
| 500mg | 984.00 € | ||
| 1mL*10mM (DMSO) | 63.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
Obeticholic Acid
CAS:459789-99-2
Obeticholic Acid (6-ECDCA, INT-747) is a high-affinity, semisynthetic, bile acid-derived FXR agonist.Cost-effective and quality-assured.
Formula:
C26H44O4
Purity:
99.02% - 99.97%
Color and Shape:
Solid
Molecular weight:
420.63
Ref: TM-T1789
| 5mg | 48.00 € | ||
| 10mg | 52.00 € | ||
| 25mg | 81.00 € | ||
| 50mg | 97.00 € | ||
| 100mg | 160.00 € | ||
| 200mg | 269.00 € | ||
| 500mg | 496.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
Sevelamer hydrochloride
CAS:152751-57-0
Sevelamer hydrochloride (Sevelamer HCl) is a phosphate binding drug used to treat hyperphosphatemia via binding …
Formula:
(C3H7N·C3H5ClO·HCl)x
Purity:
98%
Color and Shape:
Solid
Molecular weight:
186.08
Ref: TM-T6344
| 50mg | 35.00 € | ||
| 100mg | 47.00 € | ||
| 500mg | 136.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
Tropifexor
CAS:1383816-29-2
Tropifexor (LJN452) is a novel and highly potent agonist of FXR with an EC50 of …
Formula:
C29H25F4N3O5S
Purity:
99.1% - 99.85%
Color and Shape:
Solid
Molecular weight:
603.58
Ref: TM-T4379
| 1mg | 88.00 € | ||
| 5mg | 166.00 € | ||
| 10mg | 248.00 € | ||
| 25mg | 437.00 € | ||
| 50mg | 664.00 € | ||
| 100mg | 1,006.00 € | ||
| 200mg | 1,518.00 € | ||
| 500mg | 2,208.00 € | ||
| 1mL*10mM (DMSO) | 214.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
Turofexorate Isopropyl
CAS:629664-81-9
Turofexorate Isopropyl (XL335) is a potent, selective, and orally bioavailable FXR agonist with EC50 of …
Formula:
C25H24F2N2O3
Purity:
99.33% - 99.75%
Color and Shape:
Solid
Molecular weight:
438.47
Ref: TM-T6053
| 2mg | 46.00 € | ||
| 5mg | 70.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 167.00 € | ||
| 50mg | 271.00 € | ||
| 100mg | 427.00 € | ||
| 1mL*10mM (DMSO) | 76.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
DY268
CAS:1609564-75-1
DY268 is a compound based on trisubstituted pyrazolamide without any FXR agonist activity and cytotoxicity …
Formula:
C30H32N4O5S
Purity:
98.48% - 99.43%
Color and Shape:
Solid
Molecular weight:
560.66
Ref: TM-T31587
| 1mg | 40.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 123.00 € | ||
| 25mg | 241.00 € | ||
| 50mg | 444.00 € | ||
| 100mg | 640.00 € | ||
| 500mg | 1,379.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
Guggulsterone
CAS:95975-55-6
Guggulsterone (Guggulsterone E&Z) E&Z is a 3-hydroxy steroid. It has a role as an androgen.
Formula:
C21H28O2
Purity:
99.40%
Color and Shape:
Light Yellow Powder
Molecular weight:
312.45
Ref: TM-T5574
| 1mg | 35.00 € | ||
| 5mg | 66.00 € | ||
| 10mg | 112.00 € | ||
| 25mg | 198.00 € | ||
| 50mg | 270.00 € | ||
| 100mg | 399.00 € | ||
| 1mL*10mM (DMSO) | 73.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
Nidufexor
CAS:1773489-72-7
Nidufexor is an agonist for the farnesoid X receptor (FXR).
Formula:
C27H22ClN3O4
Purity:
98.67%
Color and Shape:
Solid
Molecular weight:
487.93
Ref: TM-T7886
| 1mg | 56.00 € | ||
| 5mg | 119.00 € | ||
| 10mg | 186.00 € | ||
| 25mg | 353.00 € | ||
| 50mg | 528.00 € | ||
| 100mg | 744.00 € | ||
| 1mL*10mM (DMSO) | 130.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
LY367385
CAS:198419-91-9
LY367385 is a highly effective and selective mGluR1a antagonist.
Formula:
C10H11NO4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
209.2
Ref: TM-T15818
| 10mg | 565.00 € | ||
| 50mg | 2,352.00 € |
Estimated delivery in United States, on Thursday 23 Jan 2025
INT-767
CAS:1000403-03-1
INT-767 is a highly potent farneson X receptor (FXR)/TGR5 dual agonist that prevents NASH and …
Formula:
C25H43NaO6S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
494.66
Ref: TM-T11661
| 1mg | 378.00 € |
Estimated delivery in United States, on Thursday 6 Feb 2025
GSK2324
CAS:1020567-30-9
GSK2324 is a potent FXR agonist for the treatment of NAFLD by controlling hepatic lipids …
Formula:
C29H22Cl2N2O4
Purity:
100% - 98.50%
Color and Shape:
Solid
Molecular weight:
533.4
Ref: TM-T27460
| 1mg | 319.00 € | ||
| 5mg | 769.00 € | ||
| 10mg | 1,049.00 € | ||
| 25mg | 1,560.00 € | ||
| 50mg | 2,125.00 € | ||
| 100mg | 2,763.00 € |
Estimated delivery in United States, on Thursday 6 Feb 2025
Gly-β-MCA
CAS:66225-78-3
Gly-β-MCA is an orally bioactive, entero inhibitor of the farnesoid X receptor (FXR), a bile …
Formula:
C26H43NO6
Purity:
≥98.0%
Color and Shape:
Solid
Molecular weight:
465.62
Ref: TM-T11426
| 1mg | 189.00 € |
Estimated delivery in United States, on Thursday 6 Feb 2025
