FXR
Farnesoid X Receptor (FXR) is a nuclear receptor that plays a key role in the regulation of bile acid homeostasis, lipid metabolism, and glucose regulation. FXR is a potential therapeutic target for treating liver diseases, metabolic disorders, and cardiovascular diseases. FXR inhibitors can modulate these pathways, offering insights into disease mechanisms and therapeutic strategies. At CymitQuimica, we provide a range of FXR inhibitors to support your research in hepatology, metabolism, and drug development.
Found 62 products of "FXR"
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Turofexorate Isopropyl
CAS:Turofexorate Isopropyl (XL335) is a potent, selective, and orally bioavailable FXR agonist with EC50 of 4 nM
Formula:C25H24F2N2O3Purity:98.55% - 99.73%Color and Shape:SolidMolecular weight:438.47Tauro-Obeticholic acid
CAS:Tauro-Obeticholic acid is an active Obeticholic acid metabolite. Obeticholic acid is an orally bioavailable agonist of farnesoid-X receptor (FXR).Formula:C28H49NO6SPurity:99.74% - 99.82%Color and Shape:SolidMolecular weight:527.76Ref: TM-T13092
1mg111.00€5mg260.00€10mg393.00€25mg650.00€50mg888.00€100mg1,243.00€1mL*10mM (DMSO)331.00€Ursodeoxycholic acid sodium
CAS:Ursodeoxycholic acid sodium (Sodium Ursodeoxycholate) is a naturally occurring secondary bile acid with anti-inflammatory and cytoprotective activities.
Formula:C24H40NaO4Purity:99.66% - 99.96%Color and Shape:SolidMolecular weight:415.56GW 4064
CAS:GW 4064 is an effective farnesoid X receptor (FXR) agonist (EC50 =65 nM).Formula:C28H22Cl3NO4Purity:98% - 99.94%Color and Shape:SolidMolecular weight:542.84Ref: TM-T2233
5mg52.00€10mg79.00€25mg132.00€50mg222.00€100mg403.00€200mg605.00€500mg954.00€1mL*10mM (DMSO)59.00€Obeticholic Acid
CAS:Obeticholic Acid (6-ECDCA, INT-747) is a high-affinity, semisynthetic, bile acid-derived FXR agonist.Cost-effective and quality-assured.Formula:C26H44O4Purity:99.88% - 99.97%Color and Shape:SolidMolecular weight:420.63Ref: TM-T1789
5mg46.00€10mg50.00€25mg78.00€50mg94.00€100mg155.00€200mg259.00€500mg477.00€1mL*10mM (DMSO)50.00€Sevelamer hydrochloride
CAS:Sevelamer hydrochloride (Sevelamer HCl) is a phosphate binding drug used to treat hyperphosphatemia via binding to dietary phosphate and prevents its absorption
Formula:(C3H7N·C3H5ClO·HCl)xPurity:98%Color and Shape:SolidMolecular weight:186.08Tropifexor
CAS:Tropifexor (LJN452) is a novel and highly potent agonist of FXR with an EC50 of 0.2 nM.
Formula:C29H25F4N3O5SPurity:99.3% - 99.85%Color and Shape:SolidMolecular weight:603.58Ref: TM-T4379
1mg87.00€5mg166.00€10mg248.00€25mg437.00€50mg665.00€100mg1,008.00€200mg1,520.00€500mg2,252.00€DY268
CAS:DY268 is a compound based on trisubstituted pyrazolamide without any FXR agonist activity and cytotoxicity and can be used as an effective FXR antagonist.Formula:C30H32N4O5SPurity:99.43% - 99.75%Color and Shape:SolidMolecular weight:560.66Ref: TM-T31587
1mg38.00€5mg84.00€10mg119.00€25mg233.00€50mg430.00€100mg620.00€500mg1,333.00€1mL*10mM (DMSO)93.00€BAR 501 impurity
CAS:BAR 501 impurity 在 BAR501 制剂中发现的一种杂质，可作为 G 蛋白偶联胆汁酸激活受体 (GP-BAR1) 的激动剂。 BAR501 杂质 (10 µM) 在 GP-BAR1 报告基因检测中诱导荧光素酶活性增加 150%。Formula:C26H46O3Purity:98.78%Color and Shape:SolidMolecular weight:406.64BAR502
CAS:BAR502 is a dual GPBAR1 and FXR agonist (IC50s: 0.4 μM and 2 μM).Formula:C25H44O3Purity:99.95%Color and Shape:SolidMolecular weight:392.62Guggulsterone
CAS:Guggulsterone (Guggulsterone E&Z) E&Z is a 3-hydroxy steroid. It has a role as an androgen.Formula:C21H28O2Purity:99.4% - 99.8%Color and Shape:Light Yellow PowderMolecular weight:312.45Ref: TM-T5574
1mg34.00€5mg50.00€10mg93.00€25mg152.00€50mg205.00€100mg289.00€200mg432.00€1mL*10mM (DMSO)55.00€Nidufexor
CAS:Nidufexor is an agonist for the farnesoid X receptor (FXR).Formula:C27H22ClN3O4Purity:98.67%Color and Shape:SolidMolecular weight:487.93T0901317
CAS:T0901317 is a potent and selective agonist for both LXR and FXR, with EC50 of ~50 nM and 5 μM, respectively; it inhibits nuclear factor/κB (NF/κB).Formula:C17H12F9NO3SPurity:98% - 99.64%Color and Shape:SolidMolecular weight:481.33Vidofludimus
CAS:Vidofludimus (SC12267) (4SC-101, SC12267) is a novel small molecule inhibitor of dihydroorotate dehydrogenase (DHODH).Formula:C20H18FNO4Purity:98.33% - 99.58%Color and Shape:SolidMolecular weight:355.36Glyco-Obeticholic acid
CAS:Glyco-Obeticholic acid is an active metabolite of Obeticholic acid. Obeticholic acid is an agonist of the farnesoid X receptor (FXR).Formula:C28H47NO5Purity:99.77% - 99.95%Color and Shape:SolidMolecular weight:477.68Ref: TM-T11428
1mg49.00€2mgTo inquire5mg105.00€10mg160.00€25mg313.00€50mg1,320.00€1mL*10mM (DMSO)126.00€Fexaramine
CAS:Fexaramine is a small molecule farnesoid X receptor (FXR) agonist with 100-fold increased affinity compared to natural compounds.Formula:C32H36N2O3Purity:98.87% - 99.61%Color and Shape:SolidMolecular weight:496.64Forskolin
CAS:Forskolin (Coleonol) is a natural product, an adenylate cyclase activator (EC50=0.5 μM).Formula:C22H34O7Purity:98.83% - 99.96%Color and Shape:Less Crystalline Solid Colorless Crystalline SolidMolecular weight:410.50Ref: TM-T2939
5mg43.00€10mg56.00€25mg86.00€50mg96.00€100mg144.00€200mg182.00€500mg306.00€1mL*10mM (DMSO)56.00€Cilofexor
CAS:Cilofexor inhibits binding of a synthetic peptide, Cilofexor is a farnesoid X receptor (FXR) agonist.Formula:C28H22Cl3N3O5Purity:99.86% - ≥95%Color and Shape:SolidMolecular weight:586.85Ref: TM-T7436
1mg50.00€2mg77.00€5mg124.00€10mg188.00€25mg376.00€50mg567.00€100mg747.00€200mg1,017.00€1mL*10mM (DMSO)158.00€Vonafexor
CAS:Vonafexor (EYP001) is a farnesoid X receptor (FXR, NR1H4) agonist, with anti-HBV effectsFormula:C19H15Cl3N2O5SPurity:98.74%Color and Shape:SolidMolecular weight:489.76Teduglutide
CAS:Teduglutide (ALX-0600) is a glucagon-like peptide-2 analog that increases intestinal absorption and can be used in research on short bowel syndrome (SBS).Formula:C164H252N44O55SPurity:98.08%Color and Shape:SolidMolecular weight:3752.08
