FXR
Farnesoid X Receptor (FXR) is a nuclear receptor that plays a key role in the regulation of bile acid homeostasis, lipid metabolism, and glucose regulation. FXR is a potential therapeutic target for treating liver diseases, metabolic disorders, and cardiovascular diseases. FXR inhibitors can modulate these pathways, offering insights into disease mechanisms and therapeutic strategies. At CymitQuimica, we provide a range of FXR inhibitors to support your research in hepatology, metabolism, and drug development.
Found 58 products of "FXR"
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Tauro-Obeticholic acid
CAS:<p>Tauro-Obeticholic acid is an active Obeticholic acid metabolite. Obeticholic acid is an orally bioavailable agonist of farnesoid-X receptor (FXR).</p>Formula:C28H49NO6SPurity:99.74% - 99.82%Color and Shape:SolidMolecular weight:527.76Ursodeoxycholic acid sodium
CAS:<p>Ursodeoxycholic acid sodium (Sodium Ursodeoxycholate) is a naturally occurring secondary bile acid with anti-inflammatory and cytoprotective activities.</p>Formula:C24H40NaO4Purity:99.66% - 99.96%Color and Shape:SolidMolecular weight:415.56GW 4064
CAS:<p>GW 4064 is an effective farnesoid X receptor (FXR) agonist (EC50 =65 nM).</p>Formula:C28H22Cl3NO4Purity:98% - 99.94%Color and Shape:SolidMolecular weight:542.84Obeticholic Acid
CAS:<p>Obeticholic Acid (6-ECDCA, INT-747) is a high-affinity, semisynthetic, bile acid-derived FXR agonist.Cost-effective and quality-assured.</p>Formula:C26H44O4Purity:99.88% - 99.97%Color and Shape:SolidMolecular weight:420.63Sevelamer hydrochloride
CAS:<p>Sevelamer hydrochloride (Sevelamer HCl) is a phosphate binding drug used to treat hyperphosphatemia via binding to dietary phosphate and prevents its absorption</p>Formula:(C3H7N·C3H5ClO·HCl)xPurity:98%Color and Shape:SolidMolecular weight:186.08Tropifexor
CAS:<p>Tropifexor (LJN452) is a novel and highly potent agonist of FXR with an EC50 of 0.2 nM.</p>Formula:C29H25F4N3O5SPurity:99.3% - 99.85%Color and Shape:SolidMolecular weight:603.58Turofexorate Isopropyl
CAS:<p>Turofexorate Isopropyl (XL335) is a potent, selective, and orally bioavailable FXR agonist with EC50 of 4 nM</p>Formula:C25H24F2N2O3Purity:98.55% - 99.73%Color and Shape:SolidMolecular weight:438.47BAR 501 impurity
CAS:<p>BAR 501 impurity 在 BAR501 制剂中发现的一种杂质，可作为 G 蛋白偶联胆汁酸激活受体 (GP-BAR1) 的激动剂。 BAR501 杂质 (10 µM) 在 GP-BAR1 报告基因检测中诱导荧光素酶活性增加 150%。</p>Formula:C26H46O3Purity:98.78%Color and Shape:SolidMolecular weight:406.64BAR502
CAS:<p>BAR502 is a dual GPBAR1 and FXR agonist (IC50s: 0.4 μM and 2 μM).</p>Formula:C25H44O3Purity:99.95%Color and Shape:SolidMolecular weight:392.62Guggulsterone
CAS:<p>Guggulsterone (Guggulsterone E&Z) E&Z is a 3-hydroxy steroid. It has a role as an androgen.</p>Formula:C21H28O2Purity:99.4% - 99.8%Color and Shape:Light Yellow PowderMolecular weight:312.45Nidufexor
CAS:<p>Nidufexor is an agonist for the farnesoid X receptor (FXR).</p>Formula:C27H22ClN3O4Purity:98.67%Color and Shape:SolidMolecular weight:487.93T0901317
CAS:<p>T0901317 is a potent and selective agonist for both LXR and FXR, with EC50 of ~50 nM and 5 μM, respectively; it inhibits nuclear factor/κB (NF/κB).</p>Formula:C17H12F9NO3SPurity:98% - 99.64%Color and Shape:SolidMolecular weight:481.33Vidofludimus
CAS:<p>Vidofludimus (SC12267) (4SC-101, SC12267) is a novel small molecule inhibitor of dihydroorotate dehydrogenase (DHODH).</p>Formula:C20H18FNO4Purity:98.33% - 99.58%Color and Shape:SolidMolecular weight:355.36Glyco-Obeticholic acid
CAS:<p>Glyco-Obeticholic acid is an active metabolite of Obeticholic acid. Obeticholic acid is an agonist of the farnesoid X receptor (FXR).</p>Formula:C28H47NO5Purity:99.77% - 99.95%Color and Shape:SolidMolecular weight:477.68Fexaramine
CAS:<p>Fexaramine is a small molecule farnesoid X receptor (FXR) agonist with 100-fold increased affinity compared to natural compounds.</p>Formula:C32H36N2O3Purity:98.87% - 99.61%Color and Shape:SolidMolecular weight:496.64Forskolin
CAS:<p>Forskolin (Coleonol) is a natural product, an adenylate cyclase activator (EC50=0.5 μM).</p>Formula:C22H34O7Purity:98.83% - 99.96%Color and Shape:Less Crystalline Solid Colorless Crystalline SolidMolecular weight:410.5Cilofexor
CAS:<p>Cilofexor inhibits binding of a synthetic peptide, Cilofexor is a farnesoid X receptor (FXR) agonist.</p>Formula:C28H22Cl3N3O5Purity:99.86% - ≥95%Color and Shape:SolidMolecular weight:586.85Vonafexor
CAS:<p>Vonafexor (EYP001) is a farnesoid X receptor (FXR, NR1H4) agonist, with anti-HBV effects</p>Formula:C19H15Cl3N2O5SPurity:98.74%Color and Shape:SolidMolecular weight:489.76Teduglutide
CAS:<p>Teduglutide (ALX-0600) is a glucagon-like peptide-2 analog that increases intestinal absorption and can be used in research on short bowel syndrome (SBS).</p>Formula:C164H252N44O55SPurity:98.08%Color and Shape:SolidMolecular weight:3752.08EDP-305
CAS:<p>EDP-305, an oral FXR agonist, has EC50s of 34 nM/8 nM in CHO/HEK cells, aids in PBC and NASH research with antifibrotic properties.</p>Formula:C36H58N2O5SColor and Shape:SolidMolecular weight:630.92
