HMG-CoA Reductase
HMG-CoA Reductase is a key enzyme in the mevalonate pathway, responsible for the synthesis of cholesterol and other isoprenoids. Inhibitors of HMG-CoA reductase, commonly known as statins, are widely used to lower cholesterol levels and reduce the risk of cardiovascular diseases. These inhibitors also have potential benefits in cancer and neurodegenerative disease research. At CymitQuimica, we provide a variety of HMG-CoA reductase inhibitors to support your research in lipid metabolism, cardiovascular health, and therapeutic development.
Found 35 products for "HMG-CoA Reductase".
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Atorvastatin lactone
CAS:Atorvastatin lactone is a prodrug form of atorvastatin. Which is an orally active 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor.Formula:C33H33FN2O4Purity:98.05% - 98.16%Color and Shape:SolidMolecular weight:540.6245Lipid Metabolism Compound Library
A unique collection of xnum compounds targeting lipid metabolism, can be used for high-throughput screening (HTS) and high-content screening (HCS).Color and Shape:Odour SolidPROTAC HMGCR Degrader-1
CAS:PROTACHMGCR Degrader-1 is an orally active HMGCRPROTAC degrader with an IC50 of 1.32 μM. It is a lactone prodrug derived from PROTACHMGCR Degrader-2. In vivo, PROTACHMGCR Degrader-1 achieves high plasma exposure of the active compound, leading to potent HMGCR degradation and demonstrating effective cholesterol-lowering properties. This compound is applicable for research related to hyperlipidemia.Formula:C53H77N5O9SMolecular weight:960.29HMG-CoA Reductase-IN-1
HMG-CoA Reductase-IN-1 is an inhibitor of HMG-CoA reductase, demonstrating strong inhibitory activity on HMGR and affinity for OATP1B1, with pIC50 and pKmFormula:C27H29N3O7Color and Shape:SolidMolecular weight:507.54(Rac)-5-Keto Fluvastatin
CAS:(Rac)-5-Keto Fluvastatin (rac 5-Keto Fluvastatin) is an impurity of Fluvastatin which is an inhibitor of HMG-CoA reductase.Formula:C24H24FNO4Purity:95.04%Color and Shape:SolidMolecular weight:409.4501(3S,5R)-Fluvastatin-D6 sodium
CAS:(3S,5R)-Fluvastatin D6 sodium: deuterium-labeled synthetic HMG-CoA reductase inhibitor with 8 nM IC50.Formula:C24H25FNNaO4Purity:98%Color and Shape:SolidMolecular weight:439.4847L 645164
CAS:L 645164 is an inhibitor of hydroxymethylglutaryl-CoA reductase.Formula:C22H23FO3Color and Shape:SolidMolecular weight:354.4124,25-Epoxycholesterol
CAS:24,25-Epoxycholesterol is an oxysterol agonist of the liver X receptor, known to inhibit the activity of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMG-CoA reductase) in hepatic cells. Additionally, 24,25-Epoxycholesterol plays a role in regulating cholesterol metabolism within the liver.Formula:C27H44O2Color and Shape:SolidMolecular weight:400.64Dim16 HCl
CAS:Dim16 HCl is a dual PCSK9 and HMG-CoA reductase inhibitor that enhances LDL uptake, supporting lipid metabolism and cardiovascular research.Formula:C29H39ClIN5Purity:99.07% - 99.14%Color and Shape:Yellow SolidMolecular weight:620.01Phenicin
CAS:Phenicin (Phoenicine) is a microbial metabolite and an irreversible inhibitor of HMG-CoA reductase (HMGCR). It can be isolated from cultures of Penicillium phoeniceum and Penicillium rubrum. Phenicin specifically inhibits the conversion of HMG-CoA to mevalonate catalyzed by HMGCR, thereby effectively suppressing cholesterol synthesis.Formula:C14H10O6Molecular weight:274.23Pravastatin lactone
CAS:Pravastatin lactone, a non-enzymatic stomach derivative of pravastatin, inhibits HMG-CoA reductase and stems from mevastatin.Formula:C23H34O6Color and Shape:SolidMolecular weight:406.519Lovastatin hydroxy acid sodium (Standard)
CAS:Lovastatin hydroxy acid sodium (Standard) is the standard substance of Lovastatin hydroxy acid sodium, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Lovastatin Sodium is an HMG-CoA reductase inhibitor.Formula:C24H37NaO6Color and Shape:SolidMolecular weight:444.54PPD 10558
CAS:PPD 10558, a HMG-CoA reductase inhibitor, is used potentially for treatment of primary hypercholesterolemia.Formula:C34H37FN2O6Color and Shape:SolidMolecular weight:588.67Rosuvastatin Sodium
CAS:Rosuvastatin Sodium (ZD4522 Sodium) is a competitive HMG-CoA reductase (HMGCR) inhibitor (IC50=11 nM) with lipid-lowering and anti-atherosclerotic effects.Formula:C22H27FN3NaO6SColor and Shape:White SolidMolecular weight:503.519Atorvastatin calcium hydrate
CAS:Atorvastatin calcium hydrate is an oral lipid-lowering compound belonging to the class of HMG-CoA reductase inhibitors.Formula:C33H35FN2O5CaH2OPurity:99.97%Color and Shape:White SolidMolecular weight:605.727-Ketocholesterol
CAS:7-Ketocholesterol is a metabolite of CholesterolFormula:C27H44O2Purity:97.59% - 99.40%Color and Shape:SolidMolecular weight:400.6371Fluvastatin potassium
CAS:Fluvastatin, a synthetic statin, lowers cholesterol and prevents heart disease.Formula:C24H25FKNO4Color and Shape:SolidMolecular weight:449.56Simvastatin acid ammonium
CAS:Simvastatin acid ammonium (Tenivastatin ammonium) is an HMG-CoA reductase (HMGCR) inhibitor.Formula:C25H43NO6Purity:99.79%Color and Shape:SolidMolecular weight:453.612Tenivastatin
CAS:Tenivastatin (Simvastatin acid) is an anti-hyperlipidemic HMG-CoA reductase inhibitor used in the study of primary hyperlipidemia.Formula:C25H40O6Purity:98.46%Color and Shape:SolidMolecular weight:436.5815Pravastatin
CAS:Pravastatin (CS-514) is a competitive HMG-CoA reductase inhibitor with an IC50 of 5.6 μM for sterol synthesis, capable of lowering serum cholesterol.Formula:C23H36O7Purity:99.99%Color and Shape:Brown SolidMolecular weight:424.53
