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Transferase

Transferase

Transferases are a large class of enzymes that catalyze the transfer of functional groups, such as methyl, glycosyl, and phosphate groups, from one molecule to another. Inhibitors of transferases are used to study a wide range of biological processes, including signal transduction, metabolism, and gene expression. These inhibitors are essential tools in research areas such as cancer, metabolic diseases, and epigenetics, where dysregulation of transferase activity is implicated. At CymitQuimica, we offer a comprehensive selection of transferase inhibitors to support your research in enzymology, cell signaling, and disease mechanisms.

Found 30 products of "Transferase"

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  • Prenyl-IN-1

    CAS:
    <p>Prenyl-IN-1 inhibits prenylation selectively, counters oxidative stress in Parkinson's.</p>
    Formula:C28H24ClN5O2
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:497.98
  • α-2,3-sialyltransferase-IN-1

    CAS:
    <p>α-2,3-sialyltransferase-IN-1 is a noncompetitive inhibitor of α-2,3-sialyltransferase(IC50 of 6 μM).</p>
    Formula:C28H45NO6
    Purity:98% - 98%
    Color and Shape:Solid
    Molecular weight:491.66
  • Ibiglustat (L-Malic acid)

    CAS:
    <p>Ibiglustat (L-Malic acid) (Ibiglustat L-Malic acid) is a selective, brain-penetrant, and allosteric inhibitor of glucosylceramide synthase.</p>
    Formula:C24H30FN3O7S
    Purity:99.54%
    Color and Shape:Solid
    Molecular weight:523.57
  • OSMI-1

    CAS:
    <p>OSMI-1: cell-permeable OGT inhibitor, blocks O-GlcNAcylation (IC50: 2.7 μM), no effect on other cell glycans.</p>
    Formula:C28H25N3O6S2
    Purity:96.79% - 99.39%
    Color and Shape:Solid
    Molecular weight:563.64
  • Miglustat hydrochloride

    CAS:
    <p>Miglustat hydrochloride (N-Butyldeoxynojirimycin hydrochloride) is an inhibitor of glucosylceramide synthase and can be used for studies about Type I Gaucher</p>
    Formula:C10H22ClNO4
    Purity:99.85%
    Color and Shape:Solid
    Molecular weight:255.74
  • FGTI-2734

    CAS:
    <p>FGTI-2734, a dual FT/GGT-1 inhibitor (IC50: 250/520 nM), blocks KRAS membrane binding and curbs KRAS-driven pancreatic cancer.</p>
    Formula:C26H31FN6O2S
    Purity:99.69%
    Color and Shape:Solid
    Molecular weight:510.63
  • BMS-214662 mesylate

    CAS:
    <p>BMS-214662 mesylate is a potent and selective farnesyl transferase inhibitor with an IC50 of 1.35 nM. It exhibits antitumor activity and is applicable in cancer research.</p>
    Formula:C26H27N5O5S3
    Color and Shape:Solid
    Molecular weight:585.718
  • ICMT-IN-55

    CAS:
    <p>ICMT-IN-55 (compound 31) acts as an ICMT inhibitor, exhibiting an IC50 value of 90 nM [1].</p>
    Formula:C22H26F3NO2
    Color and Shape:Solid
    Molecular weight:393.44
  • Glucosylceramide synthase-IN-4

    CAS:
    <p>Glucosylceramide Synthase-IN-4 (compound 12) serves as a potent inhibitor of glucosylceramide synthase (GCS), exhibiting an IC50 of 6.8 nM. It demonstrates superior pharmacokinetic properties and robust stability in human hepatocytes. Additionally, this compound is noted for its effective CNS penetration and acceptable PXR selectivity [1].</p>
    Formula:C22H18F5N3O3
    Color and Shape:Solid
    Molecular weight:467.39
  • Darlifarnib

    CAS:
    <p>Darlifarnib (Compound (S)-058) is an inhibitor of farnesyl transferase and geranylgeranyltransferase, with IC50 values of ≤ 10 nM and &gt; 1000 nM, respectively. It exhibits high metabolic stability in human and mouse liver microsomes, with a half-life of over 100 minutes.</p>
    Formula:C29H20N6O
    Color and Shape:Solid
    Molecular weight:468.509