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Lipoxygenase

Lipoxygenase

Lipoxygenases are a family of enzymes that catalyze the oxygenation of polyunsaturated fatty acids, leading to the production of bioactive lipid mediators such as leukotrienes and lipoxins. These mediators play critical roles in inflammation, immune responses, and cancer. Inhibitors of lipoxygenase are used to study their role in inflammatory diseases, asthma, and cancer. At CymitQuimica, we provide a variety of lipoxygenase inhibitors to support your research in inflammation, oncology, and lipid metabolism.

Found 124 products of "Lipoxygenase"

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  • Meclofenoxate hydrochloride
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    Meclofenoxate hydrochloride

    CAS:
    <p>Meclofenoxate HCl (Lucidril) boosts memory and cognition; it's a DIMETHYLAMINOETHANOL and p-chlorophenoxyacetic acid ester.</p>
    Formula:C12H16ClNO3·HCl
    Purity:97.05%
    Color and Shape:White Crystal Powder
    Molecular weight:294.17

    Ref: TM-T1401

  • Diethylcarbamazine citrate
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    Diethylcarbamazine citrate

    CAS:
    <p>Diethylcarbamazine citrate treats filariasis, targeting W. bancrofti and L. loa by inhibiting arachidonic acid in microfilaria.</p>
    Formula:C10H21N3O·C6H8O7
    Purity:99.61%
    Color and Shape:White Crystalline Powder And Animals (Epa 1998)
    Molecular weight:391.42

    Ref: TM-T1420

  • Zileuton
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    Zileuton

    CAS:
    <p>Zileuton (A 64077) inhibits 5-lipoxygenase, reduces leukotrienes, aids bronchodilation, lessens mucus/edema, and helps manage asthma symptoms.</p>
    Formula:C11H12N2O2S
    Purity:98.72% - 99.43%
    Color and Shape:Crystalline Solid
    Molecular weight:236.29

    Ref: TM-T0477

  • Lagunamycin
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    Lagunamycin

    CAS:
    <p>Lagunamycin is used as a novel 5-lipoxygenase inhibitor.</p>
    Formula:C19H21N3O4
    Color and Shape:Solid
    Molecular weight:355.39

    Ref: TM-T25601

  • Damnacanthol
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    Damnacanthol

    <p>Damnacanthol is a useful organic compound for research related to life sciences and the catalog number is T131609.</p>
    Formula:C16H12O5
    Color and Shape:Solid
    Molecular weight:284.267

    Ref: TM-T131609

  • 13-epi-12-oxo Phytodienoic Acid
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    13-epi-12-oxo Phytodienoic Acid

    CAS:
    <p>13-epi-12-oxo PDA is a lipoxygenase derivative of α-linolenic acid in green plant leaves, often isomerizing during extraction and storage.</p>
    Formula:C18H28O3
    Color and Shape:Solid
    Molecular weight:292.41

    Ref: TM-T37396

  • DKI5
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    DKI5

    CAS:
    <p>DKI5, a LOX-1 inhibitor with 22.5 μM IC50, may exhibit anti-inflammatory, antioxidant, and anti-lipid peroxidation effects in vitro.</p>
    Formula:C8H10N4S
    Purity:98%
    Color and Shape:Soild
    Molecular weight:194.26

    Ref: TM-T67870

  • 15-LOX-1 inhibitor 1
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    15-LOX-1 inhibitor 1

    CAS:
    <p>9c(i472) blocks 15-LO-1 (IC50=0.19μM), lowers NF-κB in RAW-Blue cells, &amp; cuts Nos2/lipid peroxidation in RAW 264.7 at 0.2-5μM.</p>
    Formula:C22H21ClN2O4
    Color and Shape:Solid
    Molecular weight:412.87

    Ref: TM-T36169

  • (-)-Dihydroguaiaretic acid
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    (-)-Dihydroguaiaretic acid

    <p>(-)-Dihydroguaiaretic acid is a useful organic compound for research related to life sciences and the catalog number is T126154.</p>
    Formula:C20H26O4
    Color and Shape:Solid
    Molecular weight:330.424

    Ref: TM-T126154

  • 1-Naphthyl 3,5-dinitrobenzoate
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    1-Naphthyl 3,5-dinitrobenzoate

    CAS:
    <p>1-Naphthyl 3,5-dinitrobenzoate (JMC-4) is an inhibitor of 5-LOX can be used in studies about inflammatory therapy.</p>
    Formula:C17H10N2O6
    Purity:99.79%
    Color and Shape:Solid
    Molecular weight:338.27

    Ref: TM-T21838

  • ZD-2138
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    ZD-2138

    CAS:
    <p>ZD-2138: Selective 5-LOX inhibitor, eases allergen-induced asthma attacks and airway constriction in guinea pigs.</p>
    Formula:C23H24FNO4
    Purity:99.68% - >99.99%
    Color and Shape:Solid
    Molecular weight:397.44

    Ref: TM-T68173

  • CymitQuimica logo
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    Ruthenoleuton

    <p>Ruthenoleuton is a 5-lipoxygenase (5-LOX) inhibitor with an IC50 of 3.49 μM and a Ki of 0.80 μM. It possesses antioxidant properties and is applicable in research on inflammatory diseases.</p>
    Formula:C13H16N2O2Ru
    Color and Shape:Solid
    Molecular weight:333.35

    Ref: TM-T205654

  • E 6080 HCl
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    E 6080 HCl

    CAS:
    <p>E 6080 HCl is a 5-lipoxygenase inhibitor and can be used to study bronchial diseases.</p>
    Formula:C17H20ClN3O3S2
    Purity:99.80%
    Color and Shape:Soild
    Molecular weight:413.94

    Ref: TM-T10508L

  • 5-Lipoxygenase-IN-3
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    5-Lipoxygenase-IN-3

    CAS:
    <p>Compound 14, a &lt;1 μM 5-lipoxygenase inhibitor, researches inflammation, cancer, stroke, Alzheimer's.</p>
    Formula:C19H16ClN5O
    Color and Shape:Solid
    Molecular weight:365.82

    Ref: TM-T75122

  • CBS-1114 HCl
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    CBS-1114 HCl

    CAS:
    <p>CBS-1114 HCl: 5-lipoxygenase inhibitor, anti-inflammatory, improves heart function, reduces heart's fat.</p>
    Formula:C13H14ClN3
    Purity:99.36%
    Color and Shape:Soild
    Molecular weight:247.72

    Ref: TM-T68037L

  • CMI977
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    CMI977

    CAS:
    <p>CMI977 is a potent inhibitor of 5-Lipoxygenase (5-LO).</p>
    Formula:C16H19FN2O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:322.33

    Ref: TM-T14986

  • (±)15-HEDE
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    (±)15-HEDE

    CAS:
    <p>(±)15-HEDE is produced by non-enzymatic oxidation of 11,14-eicosadienoic acid.</p>
    Formula:C20H36O3
    Color and Shape:Solid
    Molecular weight:324.505

    Ref: TM-T35510

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    h15-LOX-2 inhibitor 2

    <p>Compound 10 (h15-LOX-2 inhibitor 2) suppresses h15-LOX activity, exhibiting IC 50 and K i values of 26.9 μM and 16.4 μM, respectively.</p>
    Formula:C22H30Cl2N6O3
    Color and Shape:Solid
    Molecular weight:497.42

    Ref: TM-T200017

  • KKII5
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    KKII5

    CAS:
    <p>KKII5 is a potent inhibitor of the lipoxygenase LOX-1 with an IC50 of 19 μM.KKII5 inhibits lipid peroxidation and enhances the ability of the active centers of</p>
    Formula:C16H14N2S
    Purity:99.34%
    Color and Shape:Solid
    Molecular weight:266.36

    Ref: TM-T77288

  • Caffeoylcalleryanin
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    Caffeoylcalleryanin

    CAS:
    <p>Caffeoylcalleryanin demonstrated potent inhibitory activity against 15-lipoxygenase (15-LOX), with an IC50 value of 1.59 μM. Furthermore, ethanol extract from A. pulchra leaves (EEAPL) was found to contain compounds exhibiting antiviral properties, particularly effective against Dengue virus type 2 (DENV-2). Among these compounds, Caffeoylcalleryanin emerged as the most potent anti-DENV-2 agent, achieving a selectivity index (SI) of 20.0.</p>
    Formula:C22H24O11
    Color and Shape:Solid
    Molecular weight:464.4

    Ref: TM-TN7391