Lipoxygenase
Lipoxygenases are a family of enzymes that catalyze the oxygenation of polyunsaturated fatty acids, leading to the production of bioactive lipid mediators such as leukotrienes and lipoxins. These mediators play critical roles in inflammation, immune responses, and cancer. Inhibitors of lipoxygenase are used to study their role in inflammatory diseases, asthma, and cancer. At CymitQuimica, we provide a variety of lipoxygenase inhibitors to support your research in inflammation, oncology, and lipid metabolism.
Found 132 products for "Lipoxygenase".
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ThioLox
CAS:ThioLox, a 15-LOX-1 inhibitor (IC50: 12 μM), has anti-inflammatory, neuroprotective benefits, and guards against glutamate toxicity.Formula:C15H18N2OSPurity:99.98%Color and Shape:SolidMolecular weight:274.38Ref: TM-T67908
5mg34.00€1mL*10mM (DMSO)44.00€10mg50.00€25mg100.00€50mg166.00€100mg279.00€200mg398.00€Zileuton
CAS:Zileuton (A 64077) inhibits 5-lipoxygenase, reduces leukotrienes, aids bronchodilation, lessens mucus/edema, and helps manage asthma symptoms.Formula:C11H12N2O2SPurity:98.72% - 99.86%Color and Shape:White SolidMolecular weight:236.29CJ-13,610 hydrochloride
CAS:CJ-13,610 hydrochloride is an orally active nonredox-type inhibitor of 5-LOX and can be used in studies about the prevention of untoward pathophysiologicalFormula:C22H24ClN3O2SPurity:98.5%Color and Shape:SoildMolecular weight:429.96Ref: TM-T27026L
1mg52.00€5mg92.00€1mL*10mM (DMSO)148.00€10mg158.00€25mg335.00€50mg500.00€100mg705.00€500mg1,485.00€1-Naphthyl 3,5-dinitrobenzoate
CAS:1-Naphthyl 3,5-dinitrobenzoate (JMC-4) is an inhibitor of 5-LOX can be used in studies about inflammatory therapy.Formula:C17H10N2O6Purity:99.79%Color and Shape:SolidMolecular weight:338.27Ref: TM-T21838
5mg54.00€1mL*10mM (DMSO)55.00€10mg86.00€25mg161.00€50mg245.00€100mg346.00€200mg474.00€(±)15-HEDE
CAS:(±)15-HEDE is produced by non-enzymatic oxidation of 11,14-eicosadienoic acid.Formula:C20H36O3Color and Shape:SolidMolecular weight:324.505mPGES-1/5-LOX-IN-1
mPGES-1/5-LOX-IN-1 (compound 3j) is a potent, orally active dual inhibitor of mPGES-1 and 5-LOX, with IC50 values of 0.92 and 1.89 µM, respectively. Additionally, mPGES-1/5-LOX-IN-1 exhibits anti-inflammatory properties.Formula:C20H22N4O6SColor and Shape:SolidMolecular weight:446.12601DKI5
CAS:DKI5, a LOX-1 inhibitor with 22.5 μM IC50, may exhibit anti-inflammatory, antioxidant, and anti-lipid peroxidation effects in vitro.Formula:C8H10N4SPurity:97.08%Color and Shape:SoildMolecular weight:194.262-Methyl-1-naphthol
CAS:2-Methyl-1-naphthol is a prostaglandin G/H synthase and polyunsaturated fatty acid 5-lipoxygenase inhibitor, suitable for biochemical experiments.Formula:C11H10OPurity:98.33%Color and Shape:SolidMolecular weight:158.2CMI977
CAS:CMI977 is a potent inhibitor of 5-Lipoxygenase (5-LO).Formula:C16H19FN2O4Purity:98%Color and Shape:SolidMolecular weight:322.33Aureusidin
CAS:Aureusidin (Auresidin) shows antioxidant and lipoxygenase inhibitory activity with anti-inflammatory effects.Formula:C15H10O6Purity:98.95% - 99.18%Color and Shape:SolidMolecular weight:286.24Ref: TM-TN5634
1mg197.00€1mL*10mM (DMSO)384.00€5mg400.00€10mg590.00€25mg888.00€50mg1,243.00€100mg1,693.00€Lagunamycin
CAS:Lagunamycin is used as a novel 5-lipoxygenase inhibitor.Formula:C19H21N3O4Color and Shape:SolidMolecular weight:355.39LOX-IN-5
CAS:LOX-IN-5 (compound 22) is a non-selective LOX inhibitor.Formula:C21H25FN4O2SColor and Shape:SolidMolecular weight:416.51h15-LOX-2 inhibitor 2
Compound 10 (h15-LOX-2 inhibitor 2) suppresses h15-LOX activity, exhibiting IC 50 and K i values of 26.9 μM and 16.4 μM, respectively.Formula:C22H30Cl2N6O3Color and Shape:SolidMolecular weight:497.42Lipoxygenase
CAS:Lipoxygenase (LOX) is a dioxygenase that catalyzes the peroxidation of linoleic acid (LA) or arachidonic acid (AA) in the presence of molecular oxygen.Color and Shape:Yellow SolidCBS-1114 HCl
CAS:CBS-1114 HCl: 5-lipoxygenase inhibitor, anti-inflammatory, improves heart function, reduces heart's fat.Formula:C13H14ClN3Purity:99.93%Color and Shape:SoildMolecular weight:247.725-LOX/NO-IN-1
5-LOX/NO-IN-1 (Compound 7e) is a dual inhibitor of 5-LOX and nitric oxide release. It exhibits an IC50 value of 2.833 μM for 5-LOX and demonstrates anti-inflammatory properties.Formula:C22H18N6O4Color and Shape:SolidMolecular weight:430.42BLX3887
CAS:BLX3887 selectively inhibits 15-LO-1 (IC50 = 32 nM), not 15-LO-2, less on 5-LO/12-LO, and affects eosinophils and dendritic cells.Formula:C10H5Cl3FN3OColor and Shape:White SolidMolecular weight:308.525-LOX-IN-5
Compound 29, also known as 5-LOX-IN-5, is a 5-lipoxygenase (5-LOX) inhibitor with an inhibitory concentration 50 (IC50) of 56 nM, utilized in researchFormula:C19H18BrN3O2SPurity:98%Color and Shape:SolidMolecular weight:432.33Ferroleuton
Ferroleuton is a selective competitive inhibitor of 5-lipoxygenase with an IC50 of 0.21 μM. It demonstrates antioxidant properties, clearing 86% of DPPH at 50 μM and exhibiting activities in ABTS (EC50 = 19.42 μM) and FRAP (EC50 = 3.32 μM) assays.Formula:C13H16FeN2O2Color and Shape:SolidMolecular weight:288.12ZD-2138
CAS:ZD-2138: Selective 5-LOX inhibitor, eases allergen-induced asthma attacks and airway constriction in guinea pigs.Formula:C23H24FNO4Purity:99.68% - >99.99%Color and Shape:SolidMolecular weight:397.443-Chloroiminodibenzyl
CAS:3-Chloroiminodibenzyl ,with CAS No. 32943-25-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 3-Chloroiminodibenzyl provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C14H12ClNColor and Shape:SolidMolecular weight:229.78(S)-HEPE
CAS:8(S)-HEPE, derived from EPA via lipoxygenase, aids barnacle egg hatching at 10 nM, but it's not confirmed as the natural hatching factor.Formula:C20H30O3Color and Shape:SolidMolecular weight:318.457Enazadrem phosphate
CAS:Enazadrem phosphate is a bio-active chemical. Detailed information has not been published.Formula:C18H28N3O5PColor and Shape:SolidMolecular weight:397.4115-LOX-1 inhibitor 1
CAS:9c(i472) blocks 15-LO-1 (IC50=0.19μM), lowers NF-κB in RAW-Blue cells, & cuts Nos2/lipid peroxidation in RAW 264.7 at 0.2-5μM.Formula:C22H21ClN2O4Color and Shape:SolidMolecular weight:412.87KKII5
CAS:KKII5 is a potent inhibitor of the lipoxygenase LOX-1 with an IC50 of 19 μM.KKII5 inhibits lipid peroxidation and enhances the ability of the active centers ofFormula:C16H14N2SPurity:99.44%Color and Shape:SolidMolecular weight:266.36Ref: TM-T77288
2mg34.00€5mg52.00€1mL*10mM (DMSO)55.00€10mg79.00€25mg119.00€50mg187.00€100mg314.00€200mg447.00€13-epi-12-oxo Phytodienoic Acid
CAS:13-epi-12-oxo PDA is a lipoxygenase derivative of α-linolenic acid in green plant leaves, often isomerizing during extraction and storage.Formula:C18H28O3Color and Shape:SolidMolecular weight:292.41E 6080 HCl
CAS:E 6080 HCl is a 5-lipoxygenase inhibitor and can be used to study bronchial diseases.Formula:C17H20ClN3O3S2Purity:99.80%Color and Shape:White SolidMolecular weight:413.94Ruthenoleuton
Ruthenoleuton is a 5-lipoxygenase (5-LOX) inhibitor with an IC50 of 3.49 μM and a Ki of 0.80 μM. It possesses antioxidant properties and is applicable in research on inflammatory diseases.Formula:C13H16N2O2RuColor and Shape:SolidMolecular weight:333.35Myxochelin A
CAS:Myxochelin A from A. disciformis fights Gram-positive bacteria, inhibits 5-LO with IC50 of 1.9 μM, and is cytotoxic to colon cancer cells.Formula:C20H24N2O7Color and Shape:SolidMolecular weight:404.4195-Lipoxygenase-IN-3
CAS:Compound 14, a <1 μM 5-lipoxygenase inhibitor, researches inflammation, cancer, stroke, Alzheimer's.Formula:C19H16ClN5OColor and Shape:SolidMolecular weight:365.82Zileuton sodium
CAS:Zileuton sodium is a selective 5-LOX inhibitor, suppresses LTB4 synthesis, reduces arachidonic acid-induced edema, and is suitable for inflammation research.Formula:C11H11N2NaO2SColor and Shape:Yellow SolidMolecular weight:258.27Cinnamyl-3,4-dihydroxy-α-cyanocinnamate
CAS:Cinnamyl-3,4-dihydroxy-α-cyanocinnamate (CDC), 12/15-LO inhibitor for diabetes. Affordable Excellence: Reliable Quality You Can TrustFormula:C19H15NO4Color and Shape:SolidMolecular weight:321.334-MMPB
CAS:15-Lipoxygenase Inhibitor 1 is a selective inhibitor of 15-lipoxygenase, with an IC50 of 18 μM.Formula:C16H19N5SPurity:97.18%Color and Shape:SolidMolecular weight:313.42Ref: TM-T8794
2mg34.00€5mg52.00€1mL*10mM (DMSO)58.00€10mg86.00€25mg156.00€50mg245.00€100mg403.00€200mg568.00€Phenidone
CAS:Phenidone inhibits COX/LOX, reducing rat autoimmune paralysis and lowering blood pressure in hypertensive rats.Formula:C9H10N2OPurity:97.24%Color and Shape:White Solid Solid CrystallineMolecular weight:162.19SKF-86002
CAS:SKF-86002 is an effective inhibitor of p38 MAP kinase (IC50: 0.5-1 uM); inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50: 1 μM).Formula:C16H12FN3SPurity:98% - 99.85%Color and Shape:SolidMolecular weight:297.35Caffeic Acid
CAS:Caffeic acid is a dual inhibitor of 5-lipoxygenase and TRPV1 ion channels. High-Quality, Low-Cost!Formula:C9H8O4Purity:98.89% - 99.3%Color and Shape:Yellow Crystals From Concentrated Aqueous Solutions Alkaline Solns Turn From Yellow To Orange Alkaline Solutions Turn From Yellow To Orange (Ntp 1992)Molecular weight:180.16Phenethyl ferulate
CAS:Phenethyl ferulate is a chemopreventive against colon cancer, enhancing apoptosis in tumors and inhibiting COX/5-LOX (IC50: 4.35/5.75 μM).Formula:C18H18O4Purity:99.88% - 99.91%Color and Shape:White SolidMolecular weight:298.33Ref: TM-TN2330
1mg56.00€1mL*10mM (DMSO)114.00€5mg119.00€10mg192.00€25mg323.00€50mg475.00€100mg687.00€Malotilate
CAS:Malotilate (Kantec) is a medicine used for the therapy of liver cirrhosis.Formula:C12H16O4S2Purity:99.79% - 99.80%Color and Shape:White SolidMolecular weight:288.383-O-Acetyl-11-hydroxy-β-boswellic acid
CAS:3-O-Acetyl-11-hydroxy-beta-boswellic acid is the precursor of 3-O-acetyl-9, 11-dehydro-beta-boswellic acid(a 5-lipoxygenase inhibitor ).Formula:C32H50O5Purity:98.24%Color and Shape:SolidMolecular weight:514.74Nordihydroguaiaretic acid
CAS:Nordihydroguaiaretic acid (NDGA) is a natural lipoxygenase (5-LOX) inhibitor. Nordihydroguaiaretic acid has antioxidant effect. Cost-effective and quality-assured.Formula:C18H22O4Purity:97.82% - 99.91%Color and Shape:SolidMolecular weight:302.364',5-Dihydroxyflavone
CAS:4',5-Dihydroxyflavone is a soybean LOX-1(Ki: 102.6 μM) and yeast α-Glucosidase inhibitor (IC50: 66 μM).Formula:C15H10O4Purity:99.81%Color and Shape:SolidMolecular weight:254.24Psoralidin
CAS:Psoralidin inhibits Akt phosphorylation and phosphatidylinositol 3-kinase activation and transcriptionally.Formula:C20H16O5Purity:98% - 99.61%Color and Shape:SolidMolecular weight:336.34Ref: TM-T3399
2mg34.00€5mg50.00€1mL*10mM (DMSO)55.00€10mg81.00€25mg152.00€50mg230.00€100mg340.00€200mg497.00€PGS-IN-1
CAS:PGS-IN-1 (KME-4) is a potent inhibitor of prostaglandin synthetase (PGS, IC50: 0.28 μM) and 5-lipoxygenase (IC50: 1.05 μM).Formula:C19H26O3Purity:99.39%Color and Shape:SolidMolecular weight:302.41Indirubin-3'-monoxime
CAS:Indirubin-3'-monoxime (Indirubin-3'-oxime) is a potent inhibitor of GSK3β (IC50: 22 nM) and also inhibits CDKs ( (IC50s: 100/180/250 nM for Cdk5/p35, Cdk1/Formula:C16H11N3O2Purity:99.55%Color and Shape:Red SolidMolecular weight:277.28S-(+)-Marmesin
CAS:S-(+)-Marmesin (marmesin) is a coumarin originally isolated from the mature bark of A. marmelos,exhibiting COX-2/5-LOX dual inhibitory activity.Formula:C14H14O4Purity:98.00% - ≥98%Color and Shape:SolidMolecular weight:246.26LOX-IN-3 dihydrochloride
CAS:LOX-IN-3 dihydrochloride is an inhibitor of lysyl oxidase (LOX).Formula:C13H15Cl2FN2O2SPurity:99.95% - 99.96%Color and Shape:White SolidMolecular weight:353.24Ref: TM-T39986
1mg54.00€5mg114.00€1mL*10mM (DMSO)120.00€10mg178.00€25mg334.00€50mg557.00€100mg888.00€200mg1,251.00€BI-0115
CAS:BI-0115 inhibits LOX-1, preventing oxLDL uptake by triggering receptor inhibition and dimer formation.Formula:C15H14ClN3OPurity:99.34%Color and Shape:Yellow SolidMolecular weight:287.74Pectolinarigenin
CAS:Pectolinarigenin has hepatoprotective and anti-inflammatory properties, acting through SOD and inhibiting eicosanoids.Formula:C17H14O6Purity:98.67% - 99.88%Color and Shape:White SolidMolecular weight:314.29Ref: TM-T6S0413
1mg46.00€5mg89.00€1mL*10mM (DMSO)110.00€10mg154.00€25mg265.00€50mg409.00€100mg620.00€Xanthatin
CAS:Xanthatin exhibits cytotoxic, antibacterial, antifungal properties, may treat NSCLC, and inhibits melanoma by targeting Wnt/β-catenin and angiogenesis.Formula:C15H18O3Purity:98.48% - 99.96%Color and Shape:White SolidMolecular weight:246.3Licofelone
CAS:Licofelone (ML-3000) is a dual COX/LOX inhibitor potentially for the treatment of osteoarthritis.Formula:C23H22ClNO2Purity:99.25%Color and Shape:White SolidMolecular weight:379.88Ref: TM-T6568
5mg44.00€1mL*10mM (DMSO)48.00€10mg66.00€25mg119.00€50mg177.00€100mg264.00€200mg394.00€500mg623.00€
