Lipoxygenase
Lipoxygenases are a family of enzymes that catalyze the oxygenation of polyunsaturated fatty acids, leading to the production of bioactive lipid mediators such as leukotrienes and lipoxins. These mediators play critical roles in inflammation, immune responses, and cancer. Inhibitors of lipoxygenase are used to study their role in inflammatory diseases, asthma, and cancer. At CymitQuimica, we provide a variety of lipoxygenase inhibitors to support your research in inflammation, oncology, and lipid metabolism.
Found 133 products of "Lipoxygenase"
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Zileuton
CAS:Zileuton (A 64077) inhibits 5-lipoxygenase, reduces leukotrienes, aids bronchodilation, lessens mucus/edema, and helps manage asthma symptoms.Formula:C11H12N2O2SPurity:98.72% - 99.43%Color and Shape:Crystalline SolidMolecular weight:236.29Myxochelin A
CAS:Myxochelin A from A. disciformis fights Gram-positive bacteria, inhibits 5-LO with IC50 of 1.9 μM, and is cytotoxic to colon cancer cells.Formula:C20H24N2O7Color and Shape:SolidMolecular weight:404.419mPGES-1/5-LOX-IN-1
mPGES-1/5-LOX-IN-1 (compound 3j) is a potent, orally active dual inhibitor of mPGES-1 and 5-LOX, with IC50 values of 0.92 and 1.89 µM, respectively. Additionally, mPGES-1/5-LOX-IN-1 exhibits anti-inflammatory properties.Formula:C20H22N4O6SMolecular weight:446.12601(±)15-HEDE
CAS:(±)15-HEDE is produced by non-enzymatic oxidation of 11,14-eicosadienoic acid.Formula:C20H36O3Color and Shape:SolidMolecular weight:324.505Caffeoylcalleryanin
CAS:Caffeoylcalleryanin demonstrated potent inhibitory activity against 15-lipoxygenase (15-LOX), with an IC50 value of 1.59 μM. Furthermore, ethanol extract from A. pulchra leaves (EEAPL) was found to contain compounds exhibiting antiviral properties, particularly effective against Dengue virus type 2 (DENV-2). Among these compounds, Caffeoylcalleryanin emerged as the most potent anti-DENV-2 agent, achieving a selectivity index (SI) of 20.0.Formula:C22H24O11Color and Shape:SolidMolecular weight:464.4Lagunamycin
CAS:Lagunamycin is used as a novel 5-lipoxygenase inhibitor.Formula:C19H21N3O4Color and Shape:SolidMolecular weight:355.3913-epi-12-oxo Phytodienoic Acid
CAS:13-epi-12-oxo PDA is a lipoxygenase derivative of α-linolenic acid in green plant leaves, often isomerizing during extraction and storage.Formula:C18H28O3Color and Shape:SolidMolecular weight:292.415-Lipoxygenase-IN-3
CAS:Compound 14, a <1 μM 5-lipoxygenase inhibitor, researches inflammation, cancer, stroke, Alzheimer's.Formula:C19H16ClN5OColor and Shape:SolidMolecular weight:365.82Damnacanthol
Damnacanthol is a useful organic compound for research related to life sciences and the catalog number is T131609.Formula:C16H12O5Color and Shape:SolidMolecular weight:284.267CMI977
CAS:CMI977 is a potent inhibitor of 5-Lipoxygenase (5-LO).Formula:C16H19FN2O4Purity:98%Color and Shape:SolidMolecular weight:322.3315-LOX-1 inhibitor 1
CAS:9c(i472) blocks 15-LO-1 (IC50=0.19μM), lowers NF-κB in RAW-Blue cells, & cuts Nos2/lipid peroxidation in RAW 264.7 at 0.2-5μM.Formula:C22H21ClN2O4Color and Shape:SolidMolecular weight:412.87(-)-Dihydroguaiaretic acid
(-)-Dihydroguaiaretic acid is a useful organic compound for research related to life sciences and the catalog number is T126154.Formula:C20H26O4Color and Shape:SolidMolecular weight:330.424DKI5
CAS:DKI5, a LOX-1 inhibitor with 22.5 μM IC50, may exhibit anti-inflammatory, antioxidant, and anti-lipid peroxidation effects in vitro.Formula:C8H10N4SPurity:97.08%Color and Shape:SoildMolecular weight:194.26ZD-2138
CAS:ZD-2138: Selective 5-LOX inhibitor, eases allergen-induced asthma attacks and airway constriction in guinea pigs.Formula:C23H24FNO4Purity:99.68% - >99.99%Color and Shape:SolidMolecular weight:397.44CBS-1114 HCl
CAS:CBS-1114 HCl: 5-lipoxygenase inhibitor, anti-inflammatory, improves heart function, reduces heart's fat.Formula:C13H14ClN3Purity:99.93%Color and Shape:SoildMolecular weight:247.72ThioLox
CAS:ThioLox, a 15-LOX-1 inhibitor (IC50: 12 μM), has anti-inflammatory, neuroprotective benefits, and guards against glutamate toxicity.
Formula:C15H18N2OSPurity:99.98%Color and Shape:SoildMolecular weight:274.38h15-LOX-2 inhibitor 2
Compound 10 (h15-LOX-2 inhibitor 2) suppresses h15-LOX activity, exhibiting IC 50 and K i values of 26.9 μM and 16.4 μM, respectively.Formula:C22H30Cl2N6O3Color and Shape:SolidMolecular weight:497.42KKII5
CAS:KKII5 is a potent inhibitor of the lipoxygenase LOX-1 with an IC50 of 19 μM.KKII5 inhibits lipid peroxidation and enhances the ability of the active centers ofFormula:C16H14N2SPurity:99.44%Color and Shape:SolidMolecular weight:266.36Ref: TM-T77288
2mg37.00€5mg56.00€10mg84.00€25mg126.00€50mg197.00€100mg330.00€200mg472.00€1mL*10mM (DMSO)58.00€1-Naphthyl 3,5-dinitrobenzoate
CAS:1-Naphthyl 3,5-dinitrobenzoate (JMC-4) is an inhibitor of 5-LOX can be used in studies about inflammatory therapy.Formula:C17H10N2O6Purity:99.79%Color and Shape:SolidMolecular weight:338.27Ref: TM-T21838
5mg54.00€10mg86.00€25mg161.00€50mg245.00€100mg346.00€200mg474.00€1mL*10mM (DMSO)55.00€LOX-IN-5
CAS:LOX-IN-5 (compound 22) is a non-selective LOX inhibitor.Formula:C21H25FN4O2SColor and Shape:SolidMolecular weight:416.515-LOX-IN-5
Compound 29, also known as 5-LOX-IN-5, is a 5-lipoxygenase (5-LOX) inhibitor with an inhibitory concentration 50 (IC50) of 56 nM, utilized in researchFormula:C19H18BrN3O2SPurity:98%Color and Shape:SolidMolecular weight:432.335-LOX/NO-IN-1
5-LOX/NO-IN-1 (Compound 7e) is a dual inhibitor of 5-LOX and nitric oxide release. It exhibits an IC50 value of 2.833 μM for 5-LOX and demonstrates anti-inflammatory properties.Formula:C22H18N6O4Color and Shape:SolidMolecular weight:430.42Ferroleuton
Ferroleuton is a selective competitive inhibitor of 5-lipoxygenase with an IC50 of 0.21 μM. It demonstrates antioxidant properties, clearing 86% of DPPH at 50 μM and exhibiting activities in ABTS (EC50 = 19.42 μM) and FRAP (EC50 = 3.32 μM) assays.Formula:C13H16FeN2O2Color and Shape:SolidMolecular weight:288.12BLX3887
CAS:BLX3887 selectively inhibits 15-LO-1 (IC50 = 32 nM), not 15-LO-2, less on 5-LO/12-LO, and affects eosinophils and dendritic cells.Formula:C10H5Cl3FN3OColor and Shape:SolidMolecular weight:308.522-Methyl-1-naphthol
CAS:2-Methyl-1-naphthol is a prostaglandin G/H synthase and polyunsaturated fatty acid 5-lipoxygenase inhibitor, suitable for biochemical experiments.Formula:C11H10OPurity:98.33%Color and Shape:SolidMolecular weight:158.2E 6080 HCl
CAS:E 6080 HCl is a 5-lipoxygenase inhibitor and can be used to study bronchial diseases.Formula:C17H20ClN3O3S2Purity:99.80%Color and Shape:SoildMolecular weight:413.94Ruthenoleuton
Ruthenoleuton is a 5-lipoxygenase (5-LOX) inhibitor with an IC50 of 3.49 μM and a Ki of 0.80 μM. It possesses antioxidant properties and is applicable in research on inflammatory diseases.Formula:C13H16N2O2RuColor and Shape:SolidMolecular weight:333.35CJ-13,610 hydrochloride
CAS:CJ-13,610 hydrochloride is an orally active nonredox-type inhibitor of 5-LOX and can be used in studies about the prevention of untoward pathophysiologicalFormula:C22H24ClN3O2SPurity:98.5%Color and Shape:SoildMolecular weight:429.96Ref: TM-T27026L
1mg52.00€5mg92.00€10mg158.00€25mg335.00€50mg500.00€100mg705.00€500mg1,485.00€1mL*10mM (DMSO)148.00€Lipoxygenase
CAS:Lipoxygenase (LOX) is a dioxygenase that catalyzes the peroxidation of linoleic acid (LA) or arachidonic acid (AA) in the presence of molecular oxygen.Color and Shape:SolidEnazadrem phosphate
CAS:Enazadrem phosphate is a bio-active chemical. Detailed information has not been published.Formula:C18H28N3O5PColor and Shape:SolidMolecular weight:397.413-Chloroiminodibenzyl
CAS:Compound PDK0184, with CAS No. 32943-25-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0184 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C14H12ClNMolecular weight:229.78(S)-HEPE
CAS:8(S)-HEPE, derived from EPA via lipoxygenase, aids barnacle egg hatching at 10 nM, but it's not confirmed as the natural hatching factor.Formula:C20H30O3Color and Shape:SolidMolecular weight:318.457Aureusidin
CAS:Aureusidin (Auresidin) shows antioxidant and lipoxygenase inhibitory activity with anti-inflammatory effects.Formula:C15H10O6Purity:98.95% - 99.18%Color and Shape:SolidMolecular weight:286.24Ref: TM-TN5634
1mg197.00€5mg400.00€10mg590.00€25mg888.00€50mg1,243.00€100mg1,693.00€1mL*10mM (DMSO)384.00€Cinnamyl-3,4-dihydroxy-α-cyanocinnamate
CAS:Cinnamyl-3,4-dihydroxy-α-cyanocinnamate (CDC), 12/15-LO inhibitor for diabetes. Affordable Excellence: Reliable Quality You Can TrustFormula:C19H15NO4Color and Shape:SolidMolecular weight:321.33Zileuton sodium
CAS:Zileuton sodium (A 64077 sodium) is a potent and selective inhibitor of 5-lipoxygenase with anti-inflammatory activities.
Formula:C11H11N2NaO2SColor and Shape:SolidMolecular weight:258.27ML355
CAS:ML355, a specific, effective 12-Lipoxygenase(12-LOX) inhibitors(IC50=0.34 μM), possess favorable ADME properties.
Formula:C21H19N3O4S2Purity:98.02% - 98.2%Color and Shape:SolidMolecular weight:441.52Malotilate
CAS:Malotilate (Kantec) is a medicine used for the therapy of liver cirrhosis.Formula:C12H16O4S2Purity:99.79% - 99.79%Color and Shape:SolidMolecular weight:288.384-MMPB
CAS:15-Lipoxygenase Inhibitor 1 is a selective inhibitor of 15-lipoxygenase, with an IC50 of 18 μM.Formula:C16H19N5SPurity:97.18%Color and Shape:SolidMolecular weight:313.42Ref: TM-T8794
2mg34.00€5mg52.00€10mg86.00€25mg156.00€50mg245.00€100mg403.00€200mg568.00€1mL*10mM (DMSO)58.00€Xanthatin
CAS:Xanthatin exhibits cytotoxic, antibacterial, antifungal properties, may treat NSCLC, and inhibits melanoma by targeting Wnt/β-catenin and angiogenesis.Formula:C15H18O3Purity:98.48% - 99.96%Color and Shape:SolidMolecular weight:246.3LOX-IN-3 dihydrochloride
CAS:LOX-IN-3 dihydrochloride is an inhibitor of lysyl oxidase (LOX).Formula:C13H15Cl2FN2O2SPurity:99.96%Color and Shape:SolidMolecular weight:353.24Ref: TM-T39986
1mg57.00€5mg120.00€10mg188.00€25mg354.00€50mg588.00€100mg938.00€200mg1,320.00€1mL*10mM (DMSO)127.00€Phenethyl ferulate
CAS:Phenethyl ferulate is a chemopreventive against colon cancer, enhancing apoptosis in tumors and inhibiting COX/5-LOX (IC50: 4.35/5.75 μM).Formula:C18H18O4Purity:99.88% - 99.91%Color and Shape:SolidMolecular weight:298.33Ref: TM-TN2330
1mg56.00€5mg119.00€10mg192.00€25mg323.00€50mg475.00€100mg687.00€1mL*10mM (DMSO)114.00€Phenidone
CAS:Phenidone inhibits COX/LOX, reducing rat autoimmune paralysis and lowering blood pressure in hypertensive rats.Formula:C9H10N2OPurity:97.24%Color and Shape:White Solid Solid CrystallineMolecular weight:162.19Chebulagic acid
CAS:Chebulagic acid, isolated from the Terminalia chebula Retz, is a COX-LOX dual inhibitor.Formula:C41H30O27Purity:97.82% - 99.8%Color and Shape:SolidMolecular weight:954.66Ref: TM-TQ0180
1mg74.00€5mg157.00€10mg225.00€25mg376.00€50mg560.00€100mg798.00€1mL*10mM (DMSO)244.00€Licofelone
CAS:Licofelone (ML-3000) is a dual COX/LOX inhibitor potentially for the treatment of osteoarthritis.Formula:C23H22ClNO2Purity:99.25%Color and Shape:Yellowish SolidMolecular weight:379.88Ref: TM-T6568
5mg44.00€10mg66.00€25mg119.00€50mg177.00€100mg264.00€200mg394.00€500mg623.00€1mL*10mM (DMSO)48.00€S-(+)-Marmesin
CAS:S-(+)-Marmesin (marmesin) is a coumarin originally isolated from the mature bark of A. marmelos,exhibiting COX-2/5-LOX dual inhibitory activity.Formula:C14H14O4Purity:98.00% - ≥98%Color and Shape:SolidMolecular weight:246.26PGS-IN-1
CAS:PGS-IN-1 (KME-4) is a potent inhibitor of prostaglandin synthetase (PGS, IC50: 0.28 μM) and 5-lipoxygenase (IC50: 1.05 μM).Formula:C19H26O3Purity:99.39%Color and Shape:SolidMolecular weight:302.41Ref: TM-T10098
1mg49.00€5mg92.00€10mg167.00€25mg349.00€50mg512.00€100mg730.00€200mg982.00€1mL*10mM (DMSO)104.00€Psoralidin
CAS:Psoralidin inhibits Akt phosphorylation and phosphatidylinositol 3-kinase activation and transcriptionally.Formula:C20H16O5Purity:98% - 99.61%Color and Shape:SolidMolecular weight:336.34Ref: TM-T3399
2mg34.00€5mg50.00€10mg81.00€25mg152.00€50mg230.00€100mg340.00€200mg497.00€1mL*10mM (DMSO)55.00€SKF-86002
CAS:SKF-86002 is an effective inhibitor of p38 MAP kinase (IC50: 0.5-1 uM); inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50: 1 μM).Formula:C16H12FN3SPurity:98% - 99.85%Color and Shape:SolidMolecular weight:297.35Indirubin-3'-monoxime
CAS:Indirubin-3'-monoxime (Indirubin-3'-oxime) is a potent inhibitor of GSK3β (IC50: 22 nM) and also inhibits CDKs ( (IC50s: 100/180/250 nM for Cdk5/p35, Cdk1/Formula:C16H11N3O2Purity:99.55%Color and Shape:Dark Red SolidMolecular weight:277.283-O-Acetyl-11-hydroxy-β-boswellic acid
CAS:3-O-Acetyl-11-hydroxy-beta-boswellic acid is the precursor of 3-O-acetyl-9, 11-dehydro-beta-boswellic acid(a 5-lipoxygenase inhibitor ).Formula:C32H50O5Purity:98.24%Color and Shape:SolidMolecular weight:514.74Nordihydroguaiaretic acid
CAS:Nordihydroguaiaretic acid (NDGA) is a natural lipoxygenase (5-LOX) inhibitor. Nordihydroguaiaretic acid has antioxidant effect. Cost-effective and quality-assured.Formula:C18H22O4Purity:97.82% - 99.91%Color and Shape:SolidMolecular weight:302.36β-Boswellic acid
CAS:β-Boswellic acid (Beta-boswellic acid) and its derivatives (the major constituents of Boswellin) have anti-carcinogenic, anti-tumor, and anti-hyperlipidemicFormula:C30H48O3Purity:99.2% - 99.91%Color and Shape:Off-White SolidMolecular weight:456.70Ref: TM-TN1097
1mg58.00€5mg137.00€10mg212.00€25mg363.00€50mg527.00€100mg747.00€1mL*10mM (DMSO)161.00€ETHYL 5-HYDROXY-2-METHYLINDOLE-3-CARBOXYLATE
CAS:ETHYL 5-HYDROXY-2-METHYLINDOLE-3-CARBOXYLATE is useful for preparation and study of hypoxia-selective cytotoxicity of indolequinone antitumor agents.Formula:C12H13NO3Purity:98.9%Color and Shape:Off-White To Light Tan Crystalline PowderMolecular weight:219.24BI-0115
CAS:BI-0115 inhibits LOX-1, preventing oxLDL uptake by triggering receptor inhibition and dimer formation.Formula:C15H14ClN3OPurity:99.34%Color and Shape:SolidMolecular weight:287.74Pectolinarigenin
CAS:Pectolinarigenin has hepatoprotective and anti-inflammatory properties, acting through SOD and inhibiting eicosanoids.
Formula:C17H14O6Purity:98.67% - 99.88%Color and Shape:SolidMolecular weight:314.29Caffeic Acid
CAS:Caffeic acid is a dual inhibitor of 5-lipoxygenase and TRPV1 ion channels. High-Quality, Low-Cost!Formula:C9H8O4Purity:98.89% - 99.3%Color and Shape:Yellow Crystals From Concentrated Aqueous Solutions Alkaline Solns Turn From Yellow To Orange Alkaline Solutions Turn From Yellow To Orange (Ntp 1992)Molecular weight:180.164',5-Dihydroxyflavone
CAS:4',5-Dihydroxyflavone is a soybean LOX-1(Ki: 102.6 μM) and yeast α-Glucosidase inhibitor (IC50: 66 μM).Formula:C15H10O4Purity:99.81%Color and Shape:SolidMolecular weight:254.242,5-Di-tert-butylhydroquinone
CAS:2,5-Di-tert-butylhydroquinone (BHQ) is an effective and selective endoplasmic reticulum Ca2+-ATPase inhibitor.Formula:C14H22O2Purity:97.11%Color and Shape:PelletslargecrystalsMolecular weight:222.32Tepoxalin
CAS:Tepoxalin (RWJ 20485), potential asthma and osteoarthritis drug, inhibits COX-1, COX-2, and 5-LOX with low IC50 values.Formula:C20H20ClN3O3Purity:99.94%Color and Shape:SolidMolecular weight:385.84Ref: TM-T7724
1mg52.00€5mg113.00€10mg166.00€25mg371.00€50mg557.00€100mg792.00€200mg1,071.00€1mL*10mM (DMSO)126.00€5-O-Demethylnobiletin
CAS:5-O-Demethylnobiletin is a natural anti-inflammatory that inhibits 5-LOX without altering COX-2 expression.
Formula:C20H20O8Purity:99.83% - ≥95%Color and Shape:SolidMolecular weight:388.37FPL 62064
CAS:FPL 62064 is a potent dual inhibitor of 5-lipoxygenase (5-LOX) and COX (IC50 of 3.5 μM and 3.1 μM for RBL-1 cytosolic 5-lipoxygenase and prostaglandinFormula:C16H15N3OPurity:98.79%Color and Shape:SolidMolecular weight:265.31Ref: TM-T8356
2mg35.00€5mg52.00€10mg86.00€25mg136.00€50mg198.00€100mg298.00€200mg414.00€1mL*10mM (DMSO)73.00€ML351
CAS:ML351 is a potent and selective inhibitor of human 15-lipoxygenase-1 (15 LOX)(IC50: 200 nM).Formula:C15H11N3OPurity:97.67%Color and Shape:SolidMolecular weight:249.27Ref: TM-T21902
1mg50.00€5mg105.00€10mg167.00€25mg334.00€50mg505.00€100mg713.00€1mL*10mM (DMSO)117.00€Linoleyl alcohol
CAS:Linoleyl alcohol (CIS,CIS-9,12-OCTADECADIENOL), fatty alcohol, is a structural analog of Linoleic acid with no a-carboxyl group[1].Formula:C18H34OPurity:98.12%Color and Shape:SolidMolecular weight:266.463-Hydroxycoumarin
CAS:3-Hydroxycoumarin is a natural compound, and is human 15-LOX-1 inhibitorsFormula:C9H6O3Purity:99.5% - 99.77%Color and Shape:SolidMolecular weight:162.1411-Keto-β-boswellic acid
CAS:11-Keto-beta-boswellic acid, a novel Nrf2 activator, and a selective 5-lipoxygenase (5-LOX) inhibitor, exerts dose dependent cardioprotective effect manifested.Formula:C30H46O4Purity:99.68%Color and Shape:SolidMolecular weight:470.68Ref: TM-TN1182
1mg57.00€5mg130.00€10mg200.00€25mg338.00€50mg497.00€100mg710.00€1mL*10mM (DMSO)133.00€Terameprocol
CAS:Terameprocol (EM-1421), a synthetic NDGA derivative, shows potent anti-HIV, antiangiogenic, and anticancer properties.Formula:C22H30O4Purity:99.38%Color and Shape:SolidMolecular weight:358.47Wedelolactone
CAS:Wedelolactone (IKK Inhibitor II) inhibits NF-κB-mediated gene transcription in cells by blocking the phosphorylation and degradation of IκBα.Formula:C16H10O7Purity:98.07% - 99.87%Color and Shape:SolidMolecular weight:314.25Ref: TM-T3384
1mg34.00€5mg71.00€10mg109.00€25mg175.00€50mg314.00€100mg414.00€500mg954.00€1mL*10mM (DMSO)50.00€CAY10698
CAS:CAY10698 is a 12-lipoxygenase inhibitor (12-LO; IC50 of 5.1 μM).Formula:C17H17N3O4S2Purity:98.97%Color and Shape:SolidMolecular weight:391.46Ref: TM-T8950
2mg38.00€5mg52.00€10mg88.00€25mg161.00€50mg243.00€100mg355.00€200mg502.00€1mL*10mM (DMSO)62.00€U-73122
CAS:U-73122 (U73122) , an effective PLC inhibitor, reduces agonist-induced Ca2+ increases in platelets and PMN.Formula:C29H40N2O3Purity:97.50%Color and Shape:Solid Off-WhiteMolecular weight:464.64a-Boswellic Acid
CAS:Controlled ProductApplications The principal constitutents of frankincense (olibanum). A specific, nonredox inhibitor of 5-lipoxygenase used to treat inflammation.
References Safayhi, H. et al.: J. Pharmacol. Exp. Therap., 261, 1143 (1992); Siemoneit, U., et al.: Eur. J. Pharmacol., 606, 246 (2009); Cao, H. et al.: Pharamacol. Res., 61, 519 (2010);Formula:C30H48O3Color and Shape:NeatMolecular weight:456.74-(2-Methylpropyl)benzenemethanol
CAS:Controlled ProductFormula:C11H16OColor and Shape:NeatMolecular weight:164.24MLS000536924
CAS:MLS000536924 is a potent and selective competitive human epithelial 15-lipoxygenase-2 inhibitor.Formula:C16H15N3SColor and Shape:SolidMolecular weight:281.38tHGA
CAS:tHGA is a potent inhibitor of lipoxygenase.Formula:C18H24O4Purity:98%Color and Shape:SolidMolecular weight:304.38L 652343
CAS:L 652343 is an inhibitor of cyclooxygenase and 5-lipoxygenase in vitro. It also inhibits the synthesis of the products of both these pathways in whole cells.Formula:C22H14F3NO2S2Color and Shape:SolidMolecular weight:445.48AHR-5333
CAS:AHR-5333 an antiallergy agent.Formula:C30H33F2NO4Purity:98%Color and Shape:SolidMolecular weight:509.58PF-4191834
CAS:PF-4191834: Non-iron, non-redox 5-LOX inhibitor, IC50 = 229 nM, 300x selective over 12/15-LOX, inactive on COX enzymes.Formula:C22H23N3O2SPurity:99.83% - 99.98%Color and Shape:SolidMolecular weight:393.5Ref: TM-T16503
5mg52.00€10mg84.00€25mg155.00€50mg259.00€100mg375.00€500mg815.00€1mL*10mM (DMSO)58.00€Texasin
CAS:Texasin is a selective inhibitor of human leukocyte 5-lipoxygenase.Formula:C16H12O5Purity:98%Color and Shape:SolidMolecular weight:284.26L-651392
CAS:L-651392 is an inhibitor of leukotriene.Formula:C14H10BrNO3SColor and Shape:SolidMolecular weight:352.2SB 210661
CAS:SB 210661 is a potent and selective 5-lipoxygenase inhibitor.Formula:C16H14F2N2O4Purity:98%Color and Shape:SolidMolecular weight:336.29Enazadrem
CAS:Enazadrem is a 5-lipoxygenase inhibitor with antiinflammatory activities.
Formula:C18H25N3OPurity:98%Color and Shape:SolidMolecular weight:299.41Nafazatrom
CAS:Nafazatrom: pyrazolinone lipoxygenase inhibitor, anticancer & antithrombotic, boosts PGI2, reduces arrhythmias.Formula:C16H16N2O2Color and Shape:SolidMolecular weight:268.31LY 221068
CAS:LY 221068 is a potent antioxidant with anti-inflammatory activity.Formula:C20H30N2O2SPurity:98%Color and Shape:SolidMolecular weight:362.5315(S)-HETrE
CAS:15(S)-HETrE, a 15-lipoxygenated DGLA derivative, inhibits human 5-LO with IC50 of 4.6μM; 5% as effective in RBL cells.Formula:C20H34O3Color and Shape:SolidMolecular weight:322.48AHR-5333 mandelate
CAS:AHR-5333 mandelate is an anti-allergy agent preventing anaphylaxis and skin hypersensitivity; inhibits 5-HETE, LTB4, LTC4 synthesis.Formula:C38H41F2NO7Color and Shape:SolidMolecular weight:661.7413(S)-HpOTrE(γ)
CAS:13(S)-HpOTrE(γ) is a monohydroxy PUFA produced by the action of soybean lipoxygenase-1 (LO-1) on γ-linolenic acid.Formula:C18H30O4Color and Shape:SolidMolecular weight:310.43Leukotriene A3 methyl ester
CAS:LTA3, made from 5,8,11-eicosatrienoic acid via 5-LO, is unstable; its stable methyl ester form turns into free acid when needed.Formula:C21H34O3Color and Shape:SolidMolecular weight:334.49Setileuton tosylate
CAS:Setileuton (MK0633): a potent 5-lipoxygenase inhibitor, researched for asthma and atherosclerosis treatment.Formula:C29H25F4N3O7SColor and Shape:SolidMolecular weight:635.58Atreleuton
CAS:Atreleuton (ABT-761), reversible oral 5-LO inhibitor, selectively blocks leukotriene formation.Formula:C16H15FN2O2SPurity:98%Color and Shape:SolidMolecular weight:318.37YS-121
CAS:YS121 inhibits mPGES-1 (IC50=3.4μM) & 5-LOX (IC50=6.5μM), and lowers PGE2 in A549 cells (EC50=12μM).Formula:C20H26ClN3O2SColor and Shape:SolidMolecular weight:407.96LP117
CAS:LP117 is a novel and effective inhibitor of 5-Lipoxygenase (5-LO) product synthesis (IC50: 1.1 μM).Formula:C21H23ClN4O2SPurity:98%Color and Shape:SolidMolecular weight:430.95Fenleuton
CAS:Fenleuton is a 5-lipoxygenase inhibitor.Formula:C17H15FN2O3Purity:98%Color and Shape:SolidMolecular weight:314.31L 656224
CAS:L 656224 is a 5-LO inhibitor.Formula:C20H21ClO3Purity:98%Color and Shape:SolidMolecular weight:344.83RG 6866
CAS:RG 6866 is a inhibitor of 5-lipoxygenase.Formula:C16H17NO3Purity:98%Color and Shape:SolidMolecular weight:271.31ICI 211965
CAS:ICI 211965 is a selective and orally potent of 5-Lipoxygenase (5-LPO).Formula:C24H23NO2SPurity:98%Color and Shape:SolidMolecular weight:389.51EP6
CAS:EP6 blocks 5-LO, key in the AA cascade, reducing leukotrienes to curb inflammation and allergies.Formula:C24H30N4OPurity:98%Color and Shape:SolidMolecular weight:390.52HZ52
CAS:HZ52: Potent reversible 5-LO inhibitor; IC50 0.7 μM; blocks LTs in human leukocytes.Formula:C24H26ClN3O2SColor and Shape:SolidMolecular weight:456Cgp 8065
CAS:Cgp 8065 is a filaricidal compound, a dithiocarbamate-derivative of amoscanate.Formula:C16H15N3O4S2Color and Shape:SolidMolecular weight:377.44Fluindione
CAS:Fluindione is a hematologic drug.Formula:C15H9FO2Color and Shape:SolidMolecular weight:240.23Lipoxygenin
CAS:Lipoxygenin: IC50 of 5 μM inhibits 5-LO, hedgehog, TGF-β, activin A, BMP, Wnt signaling, and boosts cardiac marker TnnT in iPSCs.Formula:C24H22N2O4Color and Shape:SolidMolecular weight:402.44BI-L 357
CAS:BI-L 357, a prodrug of BL-L 226, is a selective, orally active inhibitor of 5-lipoxygenase.Formula:C18H18O4SColor and Shape:SolidMolecular weight:330.4
