5-HT Receptor
5-HT receptors, also known as serotonin receptors, are a group of G protein-coupled receptors (GPCRs) that mediate the effects of serotonin, a neurotransmitter involved in mood regulation, anxiety, sleep, appetite, and other physiological processes. These receptors are divided into several subtypes, each with distinct functions and pharmacological properties. 5-HT receptor modulators are widely studied for their roles in treating depression, anxiety disorders, and other neuropsychiatric conditions. At CymitQuimica, we offer a range of high-quality 5-HT receptor modulators to support your research in neuropharmacology, mood disorders, and GPCR signaling.
Found 940 products of "5-HT Receptor"
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ECPLA
CAS:<p>ECPLA is an LSD analog and a potent 5-HT2A agonist (EC50 of 14.6 nM), capable of stimulating Gq-mediated calcium flux. It exhibits high affinity for most serotonin receptors, α2-adrenergic receptors, and D2-like dopamine receptors.</p>Formula:C21H25N3OColor and Shape:SolidMolecular weight:335.44Xylamidine
CAS:<p>Xylamidine is a biochemical.</p>Formula:C19H24N2O2Color and Shape:SolidMolecular weight:312.41Quetiapine-d4 fumarate
CAS:<p>Deuterium-labeled Quetiapine fumarate; an antidepressant and anxiolytic 5-HT agonist, dopamine antagonist.</p>Formula:C25H29N3O6SPurity:98%Color and Shape:SolidMolecular weight:503.61Mirtazapine N-oxide
CAS:<p>Mirtazapine N-oxide, a mirtazapine metabolite, is produced by CYP1A2 and CYP3A4 in human liver.</p>Formula:C17H19N3OColor and Shape:SolidMolecular weight:281.359HTR2A antagonist 1
<p>HTR2A antagonist 1 (Compound 15f) is an HTR2A antagonist with an IC50 of 42.79 nM. It induces sub-G1 cell cycle arrest and apoptosis in colorectal cancer cells by activating the p53/p21/caspase 3 signaling pathway. HTR2A antagonist 1 exhibits good liver microsomal stability and is useful for colorectal cancer research.</p>Formula:C35H43Cl2F2N5O4Color and Shape:SolidMolecular weight:706.65GM-60186
<p>GM-60186, a potent inhibitor of the 5-HT receptor 2B (HTR2B) with an IC50 of 257 nM, effectively suppresses the proliferation and migration of colorectal cancer cells.</p>Formula:C30H33FN2O4Color and Shape:SolidMolecular weight:504.591-Phenylbiguanide HCl
CAS:<p>Compound PDK0269, as 5-HT3 receptor agonists(3–100 μM, pEC50 5.05±0.06), acutely increased XII (hypoglossal) burst frequency and regularity, and decreased bursts/episode . Phenylbiguanide produced a dose-related (10-500 microM) increase in the release of dopamine (280-2000%). When nomifensine (5 microM) was included in the Ringer solution, the effect of Compound PDK0269 on the release of dopamine was ameliorated or inhibited.</p>Formula:C8H12ClN5Purity:99.31%Color and Shape:SolidMolecular weight:213.67Tegaserod
CAS:<p>Tegaserod is a 5-HT4R agonist and 5-HT2B receptor antagonist with antitumor activity used in the treatment of irritable bowel syndrome (IBS).</p>Formula:C16H23N5OPurity:99.20% - 99.89%Color and Shape:SolidMolecular weight:301.39Clothiapine
CAS:<p>Clothiapine is an atypical antipsychotic of the dibenzothiazepine chemical class.</p>Formula:C18H18ClN3SPurity:99.93%Color and Shape:SolidMolecular weight:343.87Thioridazine
CAS:<p>Thioridazine: an antipsychotic, anti-anxiety drug, blocks dopamine D2, PI3K-Akt-mTOR; halts angiogenesis, kills cancer cells, targets CSCs.</p>Formula:C21H26N2S2Color and Shape:SolidMolecular weight:370.57Altanserin
CAS:<p>Altanserin, a 5-HT2A receptor binder, is tagged with F-18 for brain PET scans.</p>Formula:C22H22FN3O2SColor and Shape:SolidMolecular weight:411.49Setiptiline maleate
CAS:<p>Setiptiline maleate is a norepinephrine reuptake inhibitor, 2-adrenergic receptor antagonist, H1 receptor inverse agonist, 5-HT serotonin receptor antagonist.</p>Formula:C23H23NO4Purity:99.94%Color and Shape:SolidMolecular weight:377.43SB-269970 hydrochloride
CAS:<p>SB-269970 hydrochloride (SB-269970A) , a hydrochloride salt form of SB-269970, is a 5-HT7 receptor antagonist (pKi of 8.3) and exhibits >50-fold selectivity</p>Formula:C18H28N2O3S·HClPurity:98.45%Color and Shape:SolidMolecular weight:388.95Fluvoxamine
CAS:<p>Fluvoxamine (DU-23000) is a selective, orally available 5-HT and serotonin reuptake inhibitor (SSRI) exhibiting antidepressant effects.</p>Formula:C15H21F3N2O2Color and Shape:SolidMolecular weight:318.33SB-277011 hydrochloride
CAS:<p>SB-277011 hydrochloride (SB-277011A hydrochloride) is a D3R antagonist, which induces delayed ejaculation in rats.</p>Formula:C28H31ClN4OPurity:98.54%Color and Shape:SolidMolecular weight:475.03Cefaclor
CAS:<p>Cefaclor (Panoral) is a cephalosporin antibiotic.</p>Formula:C15H14ClN3O4SPurity:99.03% - 99.98%Color and Shape:SolidMolecular weight:367.81Ziprasidone D8
CAS:<p>Ziprasidone D8, deuterium-labeled, is a potent antipsychotic, antagonizing 5-HT and dopamine receptors.</p>Formula:C21H21ClN4OSPurity:98%Color and Shape:SolidMolecular weight:420.993-Hydroxy agomelatine
CAS:<p>3-Hydroxy agomelatine (3-Hydroxyagomelatine) is a 5-HT2C receptor antagonist used in the study of neurological disorders.</p>Formula:C15H17NO3Color and Shape:SolidMolecular weight:259.3cis-(Z)-Flupentixol dihydrochloride
CAS:<p>cis-(Z)-Flupentixol dihydrochloride (Emergil) is a dopamine receptor antagonist.</p>Formula:C23H27Cl2F3N2OSPurity:98.07%Color and Shape:SolidMolecular weight:507.44Agomelatine (L(+)-Tartaric acid)
CAS:<p>Agomelatine (S-20098) L(+)-Tartaric acid is a specific agonist of MT1 and MT2 receptors (Kis: 0.1, 0.06, 0.12, and 0.27 nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, and</p>Formula:C19H23NO8Color and Shape:SolidMolecular weight:393.39Granisetron
CAS:<p>Granisetron, a serotonin receptor (5HT-3 selective) antagonist, is used as an antinauseant and antiemetic for cancer chemotherapy.</p>Formula:C18H24N4OColor and Shape:SolidMolecular weight:312.41(R)-Praziquantel-d11
CAS:<p>(R)-Praziquantel D11 is the deuterium labeled (R)-Praziquantel.</p>Formula:C19H24N2O2Purity:98%Color and Shape:SolidMolecular weight:323.47Olanzapine D3
CAS:<p>Olanzapine D3 is the deuterium labeled Olanzapine.</p>Formula:C17H20N4SPurity:98%Color and Shape:SolidMolecular weight:315.45Eplivanserin (mixture)
CAS:<p>Eplivanserin mixture is a selective serotonin reuptake inhibitor and a 5-HT2A receptor antagonist,</p>Formula:C19H21FN2O2Color and Shape:SolidMolecular weight:328.387Aripiprazole (D8)
CAS:<p>Aripiprazole D8 (OPC-14597 D8) is the deuterium-labeled Aripiprazole. Aripiprazole is a human 5-HT1A receptor partial agonist (Ki: 4.2 nM).</p>Formula:C23H27Cl2N3O2Purity:98%Color and Shape:SolidMolecular weight:456.44BW 723C86
CAS:<p>BW 723C86 is a 5-HT2B receptor agonist with anxiolytic effects, inducing overeating and reduced grooming in rats, useful in studying neurological disorders.</p>Formula:C16H19ClN2OSPurity:99.35%Color and Shape:SolidMolecular weight:322.85SB-200646A
CAS:<p>SB-200646A: oral 5-HT2B/2C antagonist; higher affinity than 5-HT2A (pKi: 7.5, 6.9 vs 5.2); anxiolytic with in vivo effects.</p>Formula:C15H15ClN4OPurity:98%Color and Shape:SolidMolecular weight:302.76Agomelatine-d6
CAS:<p>Agomelatine D6 (S-20098 D6) is a deuterium-labeled Agomelatine. Agomelatine is a specific agonist of MT1 and MT2 receptors.</p>Formula:C15H17NO2Purity:98%Color and Shape:SolidMolecular weight:249.34Quetiapine-d4 hemifumarate
CAS:<p>Quetiapine D4 hemifumarate is the deuterium labeled Quetiapine hemifumarate. Quetiapine hemifumarate is a agonist of 5-HT receptors and a antagonist of dopamine receptor,with ntidepressant and anxiolytic.</p>Formula:C25H29N3O6SPurity:98%Color and Shape:White SolidMolecular weight:503.61Flibanserin-d4
CAS:<p>Flibanserin: Serotonin 5-HT1A agonist (Ki=1 nM), 5-HT2A antagonist (49 nM). Flibanserin D4 is deuterium-labeled.</p>Formula:C20H21F3N4OPurity:98%Color and Shape:SolidMolecular weight:394.43Sumatriptan
CAS:<p>Sumatriptan (GR 43175 free base) is a 5-HT1 receptor agonist with anti-inflammatory activity used in acute migraine and acute myocardial infarction.</p>Formula:C14H21N3O2SPurity:99.93%Color and Shape:White To Off-White Crystalline PowderMolecular weight:295.4Paliperidone Palmitate
CAS:<p>Paliperidone: atypical antipsychotic, dopamine & serotonin antagonist, affects α1/α2 adrenergic and H1 histamine receptors.</p>Formula:C39H57FN4O4Purity:98%Color and Shape:SolidMolecular weight:664.89Spiroxatrine
CAS:<p>Spiroxatrine (R 5188) is a 5-HT1α and α2-adrenergic dual antagonist with sedative activity for the study of diseases related to the cardiovascular system.</p>Formula:C22H25N3O3Purity:99.94%Color and Shape:SolidMolecular weight:379.45Clozapine-d8
CAS:<p>Clozapine-d8 is a deuterium-labeled analog of Clozapine, used as an internal standard for mass spectrometric analysis of this atypical antipsychotic.</p>Formula:C18H19ClN4Color and Shape:SolidMolecular weight:334.87Dehydroaripiprazole
CAS:<p>Dehydroaripiprazole (DM-14857), aripiprazole's active metabolite, is formed by CYP3A4 and CYP2D6, with similar antipsychotic effects.</p>Formula:C23H25Cl2N3O2Purity:98.7%Color and Shape:SolidMolecular weight:446.37Asenapine hydrochloride
CAS:<p>Asenapine hydrochloride (Org 5222 hydrochloride) is an antagonist of 5-hydroxytryptamine, adrenergic, dopamine, and histamine receptors with antipsychotic effects.</p>Formula:C17H17Cl2NOColor and Shape:SolidMolecular weight:322.23Alosetron D3 Hydrochloride
CAS:<p>Alosetron D3 (GR 68755 D3) Hydrochloride is a deuterium-labeled Alosetron. Alosetron is an antagonist of 5HT3-receptor.</p>Formula:C17H19ClN4OPurity:98%Color and Shape:SolidMolecular weight:333.83Nefazodone
CAS:<p>Nefazodone (Nefadar) is an oral antidepressant that is an antagonist of postsynaptic 5-HT 2A receptors and 5-HT 2C receptors, and SNDRI.</p>Formula:C25H32ClN5O2Purity:99.85%Color and Shape:White To Off-White Crystalline PowderMolecular weight:470.01Cariprazine D6
CAS:<p>Cariprazine D6 (RGH-188 D6) is a deuterium-labeled Cariprazine. Cariprazine is an antipsychotic agent (D3 receptors, Ki: 0.085 nM; D2 receptors, Ki: 0.49 nM).</p>Formula:C21H26D6Cl2N4OPurity:98%Color and Shape:SolidMolecular weight:433.45Ziprasidone amino acid
CAS:<p>Ziprasidone Impurity C is a byproduct of Ziprasidone, an antipsychotic that blocks 5-HT and dopamine receptors.</p>Formula:C21H23ClN4O2SColor and Shape:SolidMolecular weight:430.95Levomepromazine
CAS:<p>Levomepromazine (Methotrimeprazine) is a Ca2+ release inducer with antiviral, anti-inflammatory, neuroprotective, sedative, and anti-nociceptive activities.</p>Formula:C19H24N2OSPurity:99.15%Color and Shape:SolidMolecular weight:328.47Vilazodone-d8
CAS:<p>Vilazodone D8 is a deuterium-labeled vilazodone. Vilazodone is a combined inhibitor of serotonin specific reuptake (SSRI) and agonist of 5-HT1A receptor partial.</p>Formula:C26H27N5O2Purity:98%Color and Shape:SolidMolecular weight:449.573-Hydroxy agomelatine D3
CAS:<p>3-Hydroxy agomelatine D3 is a deuterated metabolite of Agomelatine and a 5-HT2C antagonist (IC50: 3.2 μM, Ki: 1.8 μM).</p>Formula:C15H17NO3Purity:98%Color and Shape:SolidMolecular weight:262.325-HT2B antagonist-1
CAS:<p>Orally active 5-HT2B antagonist; IC50 = 33.4 nM; potential for hepatocellular, cardiovascular, GI disease research.</p>Formula:C11H14BrN5Purity:99.965%Color and Shape:SolidMolecular weight:296.17Asenapine
CAS:<p>Asenapine (Org 5222) is a 5-HT receptor, adrenergic receptor, and histamine receptor antagonist with antipsychotic properties for the treatment of schizophrenia</p>Formula:C17H16ClNOPurity:99.64%Color and Shape:CoaMolecular weight:285.775-HT3 antagonist 5
CAS:<p>5-HT3 antagonist 5, a quinoxalin-2-carboxamide, blocks 5-HT3 receptors and has antidepressant effects in mice.</p>Formula:C16H13N3O2Purity:99.84%Color and Shape:SolidMolecular weight:279.294,4-Diphenylbutylamine hydrochloride
CAS:<p>4,4-Diphenylbutylamine shows affinity for the 5-HT2A and H1 receptors with Kis of 2589 and 1670 nM, respectively[1].</p>Formula:C16H20ClNColor and Shape:SolidMolecular weight:261.79WAY-100635
CAS:<p>WAY-100635 is a potent 5-HT 1A receptor antagonist pyramidal neuron firing frequency during conditioned reflexes; a dopamine D4 receptor agonist .</p>Formula:C25H34N4O2Purity:98.972%Color and Shape:SolidMolecular weight:422.56LY310762
CAS:<p>LY310762 is a 5-HT1D receptor antagonist with Ki of 249 nM.</p>Formula:C24H27FN2O2·HClPurity:99.8%Color and Shape:SolidMolecular weight:430.94Melperone
CAS:<p>Melperone, a butyrophenone tranquillizer, caused bradycardia in vivo and in vitro.</p>Formula:C16H22FNOPurity:98.84%Color and Shape:SolidMolecular weight:263.35
