5-HT Receptor
5-HT receptors, also known as serotonin receptors, are a group of G protein-coupled receptors (GPCRs) that mediate the effects of serotonin, a neurotransmitter involved in mood regulation, anxiety, sleep, appetite, and other physiological processes. These receptors are divided into several subtypes, each with distinct functions and pharmacological properties. 5-HT receptor modulators are widely studied for their roles in treating depression, anxiety disorders, and other neuropsychiatric conditions. At CymitQuimica, we offer a range of high-quality 5-HT receptor modulators to support your research in neuropharmacology, mood disorders, and GPCR signaling.
Found 940 products of "5-HT Receptor"
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Ansofaxine hydrochloride
CAS:<p>Ansofaxine hydrochloride (LY03005) is a serotonin-norepinephrine-dopamine reuptake inhibitor (IC50s: 723, 763 and 491 nM, respectively).</p>Formula:C24H32ClNO3Purity:99.57% - 99.77%Color and Shape:SolidMolecular weight:417.97Cyclopiazonic acid
CAS:<p>Cyclopiazonic acid (CPA) is a neurotoxic secondary metabolite (SM) made by A.</p>Formula:C20H20N2O3Purity:99.27% - 99.80%Color and Shape:SolidMolecular weight:336.38LY334370
CAS:<p>LY334370 is a selective 5-HT1F receptor agonist with a Ki of 1.6 nM</p>Formula:C21H22FN3OPurity:99.32%Color and Shape:SolidMolecular weight:351.42m-Chlorophenylbiguanide hydrochloride
CAS:<p>m-Chlorophenylbiguanide hydrochloride is a 5-HT3 receptor agonist.</p>Formula:C8H11Cl2N5Purity:99.43% - 99.87%Color and Shape:SolidMolecular weight:248.11Sevoflurane
CAS:<p>Sevoflurane (Fluoromethyl), a noncompetitive inhibitor of 5-HT3 receptor, acts as a low-soluble inhalation anesthetics.</p>Formula:C4H3F7OPurity:98%Color and Shape:Less Oil Colorless OilMolecular weight:200.05Tropisetron
CAS:<p>Tropisetron (ICS 205-930) is an α7-nicotinic receptor agonist and 5-HT3 receptor antagonist with Kis of 6.9 nM and 5.3 nM, respectively.</p>Formula:C17H20N2O2Purity:99.68%Color and Shape:White SolidMolecular weight:284.35Piboserod hydrochloride
CAS:<p>Piboserod HCl is a selective antagonist of 5-HT4 and muscarinic receptor.</p>Formula:C22H32ClN3O2Color and Shape:SolidMolecular weight:405.96SB 204741
CAS:<p>SB 204741 is a selective 5-HT2B antagonist with high affinity and pKi value of 7.1.</p>Formula:C14H14N4OSPurity:99.83%Color and Shape:SolidMolecular weight:286.35Perospirone
CAS:<p>Perospirone (Lullan) is an antagonist of serotonin 5HT2A receptors and dopamine D2 receptors.</p>Formula:C23H30N4O2SPurity:99.23%Color and Shape:White PowderMolecular weight:426.57Buclizine dihydrochloride
CAS:<p>Buclizine dihydrochloride (Buclina) is the hydrochloride salt form of buclizine, a piperazine histamine H1 receptor antagonist with primarily antiemetic and</p>Formula:C28H33ClN2·2HClPurity:98.05%Color and Shape:Off-White PowderMolecular weight:505.95Sumatriptan hydrochloride
CAS:<p>Sumatriptan hydrochloride (GR 43175), an oral 5-HT1 receptor agonist, treats migraines; Ki: 5-HT1D - 17 nM, 5-HT1B - 27 nM, 5-HT1A - 100 nM.</p>Formula:C14H22ClN3O2SColor and Shape:SolidMolecular weight:331.86Tandospirone citrate
CAS:<p>Tandospirone citrate (SM-3997 citrate) is a potent and selective 5-HT1A receptor partial agonist (Ki : 27 nM)</p>Formula:C27H37N5O9Purity:97.84% - 99.90%Color and Shape:SolidMolecular weight:575.61ARC-239
CAS:<p>ARC-239 is an agonist of α2-adrenergic receptor.</p>Formula:C24H29N3O3Color and Shape:SolidMolecular weight:407.51SB399885
CAS:<p>SB399885 is a potent, brain-penetrant, oral SR-6 antagonist with 200-fold selectivity for SR-6 receptors.</p>Formula:C18H21Cl2N3O4SPurity:98.94%Color and Shape:SolidMolecular weight:446.354F 4PP oxalate
CAS:<p>4F 4PP oxalate is a 5-HT2A antagonist.</p>Formula:C22H26FNO·C2H2O4Purity:97.34%Color and Shape:SolidMolecular weight:429.49Azaphen
CAS:<p>Azaphen (Pipofezin hydrochloride) is the reuptake of serotonin inhibitor.with antidepressant action and has sedative effects, suggesting antihistamine activity.</p>Formula:C16H21Cl2N5OPurity:97.62%Color and Shape:SolidMolecular weight:370.28Escitalopram Oxalate
CAS:<p>Escitalopram Oxalate ((S)-(+)Citalopram oxalate) is a selective serotonin (5-HT) reuptake inhibitor (SSRI) with Ki of 0.89 nM.</p>Formula:C22H23FN2O5Purity:97.39% - 99.73%Color and Shape:White SolidMolecular weight:414.43Serotonin hydrochloride
CAS:<p>Serotonin hydrochloride (Serotonin HCl) is an endogenous 5-HT receptor agonist, a monoamine neurotransmitter in the CNS, and a catechol O-methyltransferase (</p>Formula:C10H13ClN2OPurity:98.05% - 99.93%Color and Shape:White To Cream PowderMolecular weight:212.676Piboserod
CAS:<p>Piboserod (SB-207266) (SB 207266) is a selective 5-HT(4) receptor antagonist.</p>Formula:C22H31N3O2Purity:97.21% - 99.49%Color and Shape:SolidMolecular weight:369.5Ondansetron
CAS:<p>Ondansetron (GR 38032) is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic.</p>Formula:C18H19N3OPurity:99.92%Color and Shape:White To Yellow CrystalsMolecular weight:293.36SB 242084 dihydrochloride
CAS:<p>SB 242084 hydrochloride is a 5-HT2C receptor antagonist(pKi=9.0) that displays 158- and 100-fold selectivity over 5-HT2A and 5-HT2B receptors respectively.</p>Formula:C21H21Cl3N4O2Color and Shape:SolidMolecular weight:467.78Almotriptan Malate
CAS:<p>Almotriptan Malate (PNU180638), a selective 5-HT1B/1D receptor agonist, is used in the therapy of Migraine attacks in adults.</p>Formula:C17H25N3O2S·C4H6O5Purity:99.95%Color and Shape:Pale Yellow SolidMolecular weight:469.55S1RA hydrochloride
CAS:<p>S1RA hydrochloride (E-52862 hydrochloride) is an effective and specific sigma-1 receptor(σ1R, Ki: 17 nM) antagonist, and has good selectivity against σ2R (Ki ></p>Formula:C20H24ClN3O2Purity:98% - 99.84%Color and Shape:SolidMolecular weight:373.87Cariprazine
CAS:<p>Cariprazine (RGH-188) is a novel antipsychotic drug candidate that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate</p>Formula:C21H32Cl2N4OPurity:99.68% - 99.87%Color and Shape:SolidMolecular weight:427.41SKF-83566
CAS:<p>SKF-83566: Blood-brain permeable, orally active D1 dopamine antagonist; weaker 5-HT2 antagonist, Ki=11 nM.</p>Formula:C17H18BrNOPurity:95.00% - 99.82%Color and Shape:SolidMolecular weight:332.23Nelotanserin
CAS:<p>Nelotanserin (APD125): strong 5-HT2A inverse agonist (IC50: 1.7 nM), moderate 5-HT2C (79 nM), weak 5-HT2B (791 nM).</p>Formula:C18H15BrF2N4O2Purity:98.42% - 99.88%Color and Shape:SolidMolecular weight:437.24Nemifitide acetate(173240-15-8 free base)
<p>Nemifitide acetate, synthetic 5-amino acid antidepressant, has quick effect, mimics MIF.</p>Formula:C35H47FN10O8Purity:97.97%Color and Shape:SolidMolecular weight:754.85Eltoprazine
CAS:<p>Eltoprazine(DU28853) is a serenic or antiaggressive agent which as an agonist at the 5-HT1A and 5-HT1B receptors and as an antagonist at the 5-HT2C receptor.</p>Formula:C12H16N2O2Color and Shape:SolidMolecular weight:220.27ML 10302
CAS:<p>ML 10302 is a potent 5-HT4 agonist with Ki of 1.07 nM, boosts bowel movement, and may aid in neurology research.</p>Formula:C15H21ClN2O3Color and Shape:SolidMolecular weight:312.79SAX-187
CAS:<p>SAX-187 (SAX-187) has high-affinity binding at the human 5-HT6 receptor.</p>Formula:C15H13ClN4O2S2Purity:97.82% - 98%Color and Shape:SolidMolecular weight:380.87BMY 7378 dihydrochloride
CAS:<p>BMY 7378 dihydrochloride (BMY7378 HCl) , α1D-adrenergic receptor antagonist, is a weak partial agonist/antagonist of 5-HT1A receptor.</p>Formula:C22H33Cl2N3O3Purity:97.32% - 99.08%Color and Shape:SolidMolecular weight:458.42F-15599
CAS:<p>F-15599 is a highly selective G-protein biased 5-HT1A receptor agonist(Ki : 3.4 nM).</p>Formula:C19H21ClF2N4OPurity:98.72%Color and Shape:SolidMolecular weight:394.85Pirenperone
CAS:<p>Pirenperone is a putative 5-HT2 receptor antagonist with the central antiserotonergic and antidopaminergic action.</p>Formula:C23H24FN3O2Purity:99.2%Color and Shape:SolidMolecular weight:393.45Zotepine
CAS:<p>Zotepine, an antipsychotic agent, is a potent antagonist of 5-HT2A, 5-HT2C, Histamine H1, α1-adrenergic, and Dopamine D2 receptors, with Kds of 2.6 nM, 3.2 nM,</p>Formula:C18H18ClNOSPurity:99.78%Color and Shape:SolidMolecular weight:331.86Lurasidone
CAS:<p>Lurasidone (SM-13496) is an antagonist of both dopamine D2 and 5-HT7(IC50=1.68 and 0.495 nM, respectively).It also a partial agonist of 5-HT1A receptor(IC50 : 6</p>Formula:C28H36N4O2SPurity:99.78% - 99.91%Color and Shape:SolidMolecular weight:492.68Metoclopramide
CAS:<p>Metoclopramide: dopamine D2 antagonist, treats nausea, vomiting, gastroparesis, GERD; safe for pregnancy.</p>Formula:C14H22ClN3O2Purity:99.75%Color and Shape:SolidMolecular weight:299.80Ziprasidone mesylate
CAS:<p>Ziprasidone mesylate (CP-88059), an oral 5-HT & dopamine blocker, binds D2, 5-HT2A, 5-HT1A with Ki values: 4.8, 0.42, 3.4 nM.</p>Formula:C22H25ClN4O4S2Color and Shape:SolidMolecular weight:509.04RS-127445
CAS:<p>RS-127445 (MT500) is a selective 5-HT2B receptor antagonist with pKi of 9.5 and pIC50 of 10.4, exhibits >1000-fold selectivity against other 5-HT receptors.</p>Formula:C17H16FN3Purity:99.32%Color and Shape:SolidMolecular weight:281.33Harmine
CAS:<p>Harmine (Telepathine) is an alkaloid isolated from seeds of Peganum harmala.</p>Formula:C13H12N2OPurity:98.29% - 99.92%Color and Shape:Off-White SolidMolecular weight:212.25Spiperone hydrochloride
CAS:<p>5-HT2A serotonin and selective D2-like dopamine receptor antagonist</p>Formula:C23H27ClFN3O2Purity:98%Color and Shape:SolidMolecular weight:431.93Ramosetron hydrochloride
CAS:<p>Ramosetron hydrochloride (YM-060) is a serotonin 5-HT3 receptor antagonist. It is used to treat diarrhea-predominant irritable bowel syndrome and nausea.</p>Formula:C17H18ClN3OPurity:99.95%Color and Shape:SolidMolecular weight:315.8Rotundine
CAS:<p>Rotundine (Gindarine) (L-tetrahydropalmatine, L-THP) is a selective dopamine D1 receptor antagonist with IC50 of 166 nM.</p>Formula:C21H25NO4Purity:99.8% - 99.91%Color and Shape:Off-White SolidMolecular weight:355.43Trazodone
CAS:<p>Trazodone (AF-1161), a 5-HT 2A/2C receptor antagonist, is used as an antidepressant for treating major anxiety disorders and depressive disorder.</p>Formula:C19H22ClN5OPurity:99.79% - 99.92%Color and Shape:White To Off-White Crystalline PowderMolecular weight:371.861-(1-Naphthyl) piperazine hydrochloride
CAS:<p>1-(1-Naphthyl) piperazine hydrochloride (1-naphthalen-1-ylpiperazine hydrochloride) is a serotonergic ligand which could bind nonselectively with multiple</p>Formula:C14H17ClN2Purity:98.27%Color and Shape:SolidMolecular weight:248.75A-582941 dihydrochloride
CAS:<p>A-582941 dihydrochloride (A 582941) is a Selective agonist of α7 nAChR partial</p>Formula:C17H22Cl2N4Purity:99.55%Color and Shape:SolidMolecular weight:353.29Sertindole
CAS:<p>Sertindole, atypical antipsychotic, targets D2, 5-HT1D, 5-HT2A, 5-HT2C receptors (Kds: 2.7, 20, 0.14, 6 nM).</p>Formula:C24H26ClFN4OPurity:99.87% - 99.92%Color and Shape:Off-White To Pale Yellow SolidMolecular weight:440.94Rizatriptan benzoate
CAS:<p>Rizatriptan benzoate (MK-462 Benzoate) selectively binds to and activates serotonin (5-HT) 1B receptors and 5-HT 1D receptors providing relief of migraine</p>Formula:C22H25N5O2Purity:99% - 99.79%Color and Shape:White To Off-White Crystalline PowderMolecular weight:391.47PU02
CAS:<p>PU02 (6-[(1-Naphthalenylmethyl)thio]-9H-purine) is a potent and selective antagonist of 5-HT3 receptor.</p>Formula:C16H12N4SPurity:99.35%Color and Shape:SolidMolecular weight:292.36Pimavanserin tartrate
CAS:<p>Pimavanserin tartrate is a potent 5-HT 2A receptor inverse agonist used to treat Parkinson's disease-related psychosis.Cost-effective and quality-assured.</p>Formula:C50H68F2N6O4·C4H6O6Purity:99.24% - 99.98%Color and Shape:SolidMolecular weight:1005.2Methiothepin mesylate
CAS:<p>Methiothepin mesylate (Metitepine mesylate) is a potent and non-selective 5-HT2 receptor antagonist, used as an antipsychotic.</p>Formula:C21H28N2O3S3Purity:98% - 99.92%Color and Shape:SolidMolecular weight:452.65
