CaMK
Calcium/Calmodulin-Dependent Protein Kinase (CaMK) inhibitors are compounds that block the activity of CaMK, a kinase involved in regulating various cellular processes, including synaptic plasticity, memory formation, and gene expression in the nervous system. CaMK plays a critical role in translating calcium signals into cellular responses, and its dysregulation is associated with neurological disorders. Inhibitors of CaMK are valuable tools for studying synaptic signaling, learning, and memory. At CymitQuimica, we offer CaMK inhibitors to support your research in synaptic plasticity, cognitive function, and neuropharmacology.
Found 68 products of "CaMK"
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A-3 hydrochloride
CAS:<p>A-3 hydrochloride: potent, reversible kinase antagonist; permeable; inhibits PKC, CKI, PKA, CKII, MLCK; Ki: 4.3-80 μM.</p>Formula:C12H14Cl2N2O2SPurity:99.32%Color and Shape:SolidMolecular weight:321.22Y-33075 dihydrochloride
CAS:<p>Y-33075 dihydrochloride is a selective inhibitor of ROCK(IC50 of 3.6 nM).</p>Formula:C16H18Cl2N4OPurity:98.88% - 99.89%Color and Shape:SolidMolecular weight:353.25Trifluoperazine dihydrochloride
CAS:<p>Trifluoperazine dihydrochloride (SKF5019) is a potent dopamine D2 receptor inhibitor used as an antipsychotic and an antiemetic.</p>Formula:C21H26Cl2F3N3SPurity:99.57% - 99.96%Color and Shape:Cream Fine PowderMolecular weight:480.43Elziverine
CAS:<p>Elziverine: oral calmodulin antagonist, inhibits Ca-induced acanthocyte formation, potential for neurological and cognitive disorder treatment.</p>Formula:C32H37N3O5Purity:99.79%Color and Shape:SolidMolecular weight:543.65Nifedipine
CAS:<p>Nifedipine (Procardia) is a dihydropyridine calcium channel blocking agent.</p>Formula:C17H18N2O6Purity:99.39% - 99.49%Color and Shape:Yellow Crystals Physical Description Odorless Yellow Crystals Or Powder Tasteless (Ntp 1992)Molecular weight:346.33Dibucaine
CAS:<p>Dibucaine (Cinchocaine), a local anesthetic of the amide type, is now usually used for surface anesthesia.</p>Formula:C20H29N3O2Purity:99.698% - 99.88%Color and Shape:Colorless Or Almost Colorless Powder SolidMolecular weight:343.46TAT-CN21 (scrambled)
<p>TAT-CN21(scrambled) is a control peptide lacking specific targeting activity and serves as a negative control for TatCN21. TatCN21 is an effective and selective inhibitory peptide for calcium/calmodulin-dependent protein kinase II (CaMKII).</p>Color and Shape:Odour SolidFasciculic acid A
CAS:<p>Fasciculic acid A is a calmodulin antagonist isolated from mushroom Naematoloma fasciculare.</p>Formula:C36H60O8Color and Shape:SolidMolecular weight:620.868Fasciculic acid B
CAS:<p>Fasciculic acid B: ester of fasciculol B, 3-hydroxy-methylglutaric acid; a calmodulin antagonist from Naematoloma fasciculare.</p>Formula:C36H60O9Purity:98%Color and Shape:SolidMolecular weight:636.86Calmodulin-Dependent Protein Kinase II 290-309 acetate
<p>Calmodulin-Dependent Protein Kinase II 290-309 acetate is an effective antagonist of Ca2+/calmodulin-dependent protein kinase II (IC50 = 52 nM).</p>Formula:C105H189N31O26SPurity:96.7%Color and Shape:SolidMolecular weight:2333.88Encecalinol
CAS:<p>Encecalinol, a compound isolated from the aerial parts of Ageratina grandifolia, acts as a potent inhibitor of calmodulin [1].</p>Formula:C14H18O3Color and Shape:SolidMolecular weight:234.29Beauverolide Ja
CAS:<p>Beauverolide Ja: cyclotetradepsipeptide, CaM inhibitor; Kd 0.078 μM, Ki 0.39 μM; from Isaria fumosorosea.</p>Formula:C35H46N4O5Color and Shape:SolidMolecular weight:602.76CALP2
CAS:<p>CALP2 is a CaM antagonist blocking EF-hand/Ca2+ site; inhibits CaM phosphodiesterase, raises Ca2+, and activates alveolar macrophages.</p>Formula:C68H104N14O13SPurity:98%Color and Shape:SolidMolecular weight:1357.72CALP2 TFA
<p>CALP2 TFA, a CaM antagonist with 7.9 µM Kd, blocks CaM-dependent enzymes, boosts Ca2+ levels, and activates macrophages.</p>Formula:C70H105F3N14O15SColor and Shape:SolidMolecular weight:1471.72Acremonidin A
CAS:<p>Acremonidin A, from Purpureocillium lilacinum, is a strong CaM inhibitor binding to hCaM M124C-mBBr with a Kd of 19.40 nM.</p>Formula:C33H26O12Color and Shape:SolidMolecular weight:614.55Cloxacepride
CAS:<p>cloxacepride is a CaM antagonist that is used to treat asthma disease.</p>Formula:C22H27Cl2N3O4Purity:99.62%Color and Shape:SolidMolecular weight:468.37Calmodulin-Dependent Protein Kinase II (281-309)
CAS:<p>Calmodulin-Dependent Protein Kinase II (281-309) is a synthetic peptide that can be phosphorylated at Thr286 by PKC and inhibits CaM kinase II (IC50 = 80 nM).</p>Formula:C146H254N46O39S3Purity:98%Color and Shape:SolidMolecular weight:3374.06Fasciculic acid C
CAS:<p>Fasciculic acid C is a calmodulin antagonist isolated from mushroom Naematoloma fasciculare.</p>Formula:C38H63NO11Purity:98%Color and Shape:SolidMolecular weight:709.91RA306
<p>RA306 is an orally active CAMK2 inhibitor that effectively disrupts the PEAK1/CAMK2 signaling pathway. It demonstrates anti-tumor activity by inhibiting proliferation, migration, and invasion of breast cancer cells. Additionally, RA306 shows potential in cardiac disease research, as it improves dilated cardiomyopathy in mice.</p>Color and Shape:Odour SolidTAT-CN21
<p>TatCN21, with an IC 50 of 77 nM, serves as a potent and selective inhibitor peptide of the calcium/calmodulin-dependent protein kinase II (CaMKII), a ubiquitously-expressed multifunctional serine/threonine protein kinase. It is particularly useful in research pertaining to ischemia and neurodegenerative diseases.</p>Formula:C169H303N69O43Color and Shape:SolidMolecular weight:3989.65
