CaMK
Calcium/Calmodulin-Dependent Protein Kinase (CaMK) inhibitors are compounds that block the activity of CaMK, a kinase involved in regulating various cellular processes, including synaptic plasticity, memory formation, and gene expression in the nervous system. CaMK plays a critical role in translating calcium signals into cellular responses, and its dysregulation is associated with neurological disorders. Inhibitors of CaMK are valuable tools for studying synaptic signaling, learning, and memory. At CymitQuimica, we offer CaMK inhibitors to support your research in synaptic plasticity, cognitive function, and neuropharmacology.
Found 71 products for "CaMK".
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Trifluoperazine dihydrochloride
CAS:Trifluoperazine dihydrochloride (SKF5019) is a potent dopamine D2 receptor inhibitor used as an antipsychotic and an antiemetic.Formula:C21H26Cl2F3N3SPurity:99.57% - 99.96%Color and Shape:Cream Fine PowderMolecular weight:480.43Y-33075 dihydrochloride
CAS:Y-33075 dihydrochloride is a selective inhibitor of ROCK(IC50 of 3.6 nM).Formula:C16H18Cl2N4OPurity:98.88% - 99.89%Color and Shape:SolidMolecular weight:353.25Ref: TM-T13384L
1mg34.00€5mg66.00€1mL*10mM (DMSO)78.00€10mg102.00€25mg192.00€50mg341.00€100mg510.00€200mg732.00€A-3 hydrochloride
CAS:A-3 hydrochloride: potent, reversible kinase antagonist; permeable; inhibits PKC, CKI, PKA, CKII, MLCK; Ki: 4.3-80 μM.Formula:C12H14Cl2N2O2SPurity:99.32%Color and Shape:SolidMolecular weight:321.22Ref: TM-T14069
1mg34.00€5mg63.00€10mg90.00€1mL*10mM (DMSO)95.00€25mg161.00€50mg260.00€100mg416.00€500mg888.00€Elziverine
CAS:Elziverine: oral calmodulin antagonist, inhibits Ca-induced acanthocyte formation, potential for neurological and cognitive disorder treatment.Formula:C32H37N3O5Purity:99.79%Color and Shape:SolidMolecular weight:543.65Syntide 2 TFA
Syntide 2 (TFA) is a CaMKII substrate that selectively hinders GA response without affecting other plant processes.Formula:C70H123N20F3O20Color and Shape:SolidMolecular weight:1621.84Beauverolide Ja
CAS:Beauverolide Ja: cyclotetradepsipeptide, CaM inhibitor; Kd 0.078 μM, Ki 0.39 μM; from Isaria fumosorosea.Formula:C35H46N4O5Color and Shape:SolidMolecular weight:602.76Purine riboside-5'-O-triphosphate sodium
CAS:Purine riboside-5'-O-triphosphate sodium is an active metabolite of Nebularine and acts as an inhibitor of DNA primase ATP and GTP polymerization activities, with IC50 values of 35 µM and 28 µM, respectively. It also inhibits calmodulin-dependent protein kinase II (CaMKII), with a Ki value of 590 µM.Formula:C10H11N4Na4O13P3Color and Shape:SolidMolecular weight:580.09Cloxacepride
CAS:cloxacepride is a CaM antagonist that is used to treat asthma disease.Formula:C22H27Cl2N3O4Purity:99.76%Color and Shape:SolidMolecular weight:468.37Encecalinol
CAS:Encecalinol, a compound isolated from the aerial parts of Ageratina grandifolia, acts as a potent inhibitor of calmodulin [1].Formula:C14H18O3Color and Shape:SolidMolecular weight:234.29Fasciculic acid A
CAS:Fasciculic acid A is a calmodulin antagonist isolated from mushroom Naematoloma fasciculare.Formula:C36H60O8Color and Shape:SolidMolecular weight:620.868Calmodulin Binding Peptide 1
CAS:Calmodulin Binding Peptide 1, a high-affinity MLCK-derived inhibitor, blocks IP3-induced Ca2+ release.Formula:C231H373N69O70S2Purity:98%Color and Shape:SolidMolecular weight:5301.1CALP2 TFA
CALP2 TFA, a CaM antagonist with 7.9 µM Kd, blocks CaM-dependent enzymes, boosts Ca2+ levels, and activates macrophages.Formula:C70H105F3N14O15SColor and Shape:SolidMolecular weight:1471.72TAT-CN21
TAT-CN21 is a cell-permeable CaMKII inhibitory peptide used to study neuronal excitotoxicity and ischemic injury by blocking CaMKII activity.Formula:C169H303N69O43Color and Shape:SolidMolecular weight:3989.65CALP2
CAS:CALP2 is a CaM antagonist blocking EF-hand/Ca2+ site; inhibits CaM phosphodiesterase, raises Ca2+, and activates alveolar macrophages.Formula:C68H104N14O13SPurity:98%Color and Shape:SolidMolecular weight:1357.72TAT-CN21 (scrambled)
TAT-CN21(scrambled) is a control peptide lacking specific targeting activity and serves as a negative control for TatCN21. TatCN21 is an effective and selective inhibitory peptide for calcium/calmodulin-dependent protein kinase II (CaMKII).Color and Shape:Odour SolidRA306
RA306 is an orally active CAMK2 inhibitor that effectively disrupts the PEAK1/CAMK2 signaling pathway. It demonstrates anti-tumor activity by inhibiting proliferation, migration, and invasion of breast cancer cells. Additionally, RA306 shows potential in cardiac disease research, as it improves dilated cardiomyopathy in mice.Color and Shape:Odour SolidCalmodulin-Dependent Protein Kinase II (281-309)
CAS:Calmodulin-Dependent Protein Kinase II (281-309) is a synthetic peptide that can be phosphorylated at Thr286 by PKC and inhibits CaM kinase II (IC50 = 80 nM).Formula:C146H254N46O39S3Purity:98%Color and Shape:SolidMolecular weight:3374.06Acremonidin A
CAS:Acremonidin A, from Purpureocillium lilacinum, is a strong CaM inhibitor binding to hCaM M124C-mBBr with a Kd of 19.40 nM.Formula:C33H26O12Color and Shape:SolidMolecular weight:614.55Fasciculic acid C
CAS:Fasciculic acid C is a calmodulin antagonist isolated from mushroom Naematoloma fasciculare.Formula:C38H63NO11Purity:98%Color and Shape:SolidMolecular weight:709.91Fluphenazine-N-2-chloroethane (hydrochloride)
CAS:Fluphenazine: antipsychotic, binds dopamine D2 (Ki=0.55nM), inhibits calmodulin. Its derivative adds irreversible D2 antagonism and anticancer potential.Formula:C22H27Cl3F3N3SColor and Shape:SolidMolecular weight:528.89
