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GluR

GluR

Glutamate Receptor inhibitors are compounds that block the activity of glutamate receptors, which are the main excitatory neurotransmitter receptors in the brain. These receptors play a pivotal role in synaptic transmission, plasticity, learning, and memory. Dysregulation of glutamate signaling is associated with various neurological disorders, including epilepsy, stroke, and neurodegenerative diseases. GluR inhibitors are essential for investigating the mechanisms of excitotoxicity and developing neuroprotective strategies. At CymitQuimica, we offer a range of glutamate receptor inhibitors to support your research in synaptic function, neuroprotection, and cognitive disorders.

Found 255 products of "GluR"

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  • Biphenylindanone A
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    Biphenylindanone A

    CAS:
    <p>Biphenylindanone A is a selective potentiator of human mGluR2 (hmGluR2),and for the treatment of neurological disorders.</p>
    Formula:C30H30O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:454.56

    Ref: TM-T14615

  • MFZ 10-7
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    MFZ 10-7

    CAS:
    <p>MFZ 10-7 is anegative allosteric modulator of the mGluR5.</p>
    Formula:C15H9FN2
    Purity:99.80%
    Color and Shape:Solid
    Molecular weight:236.24

    Ref: TM-T22976

  • JNJ-46281222
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    JNJ-46281222

    CAS:
    <p>JNJ-46281222: mGlu2-selective, potent PAM, Kd = 1.7 nM, pEC50 = 7.71.</p>
    Formula:C23H25F3N4
    Color and Shape:Solid
    Molecular weight:414.47

    Ref: TM-T15618

  • MGS-0039
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    MGS-0039

    CAS:
    <p>MGS-0039: Group II mGluR2/3 antagonist, non-serotonergic antidepressant-like effect, AMPA involvement, regulates dopamine in NAc.</p>
    Formula:C15H14Cl2FNO5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:378.18

    Ref: TM-T28034

  • FPTQ
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    FPTQ

    CAS:
    <p>FPTQ is a highly effective antagonist of mGluR 1, displaying IC50 values of 6 nM and 1.4 nM for human and mouse mGluR1 respectively [1].</p>
    Formula:C17H12FN5
    Purity:99.68% - 99.88%
    Color and Shape:Solid
    Molecular weight:305.31

    Ref: TM-T5509

  • VU6005649
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    VU6005649

    CAS:
    <p>VU6005649 is an agonist of CNS penetrant mGlu7/8 receptor (EC50s: 0.65 μM and 2.6 μM for mGlu7 receptor and mGlu8 receptor, respectively).</p>
    Formula:C16H12F5N3O
    Purity:99.87%
    Color and Shape:Solid
    Molecular weight:357.28

    Ref: TM-T13321

  • VU6012962
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    VU6012962

    CAS:
    <p>VU6012962 is an orally bioavailable negative allosteric modulator of CNS-penetrant metabotropic glutamate receptor 7(mGlu7; IC50: 347 nM).</p>
    Formula:C21H19F3N4O4
    Purity:99.61% - 99.74%
    Color and Shape:Solid
    Molecular weight:448.4

    Ref: TM-T13323

  • Pomaglumetad methionil hydrochloride
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    Pomaglumetad methionil hydrochloride

    CAS:
    <p>LY2140023 hydrochloride: oral methionine prodrug of LY404039, a selective mGlu2/3 agonist, studied for schizophrenia.</p>
    Formula:C12H19ClN2O7S2
    Purity:98.57%
    Color and Shape:Solid
    Molecular weight:402.87

    Ref: TM-T61972

  • Licostinel
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    Licostinel

    CAS:
    <p>Licostinel (CGP 63446) is a glutamate receptor antagonist. Licostinel protects against permanent focal cerebral ischemia.</p>
    Formula:C8H3Cl2N3O4
    Purity:98.02%
    Color and Shape:Solid
    Molecular weight:276.03

    Ref: TM-T27828

  • cis-PDA
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    cis-PDA

    CAS:
    <p>cis-PDA (cis PDA) is a general ionotropic receptor antagonist. cis-PDA acts by blocking NMDA, AMPA, and kainate-mediated responses.</p>
    Formula:C7H11NO4
    Purity:98.71%
    Color and Shape:White Solid
    Molecular weight:173.17

    Ref: TM-T20571

  • (2R,4R)-APDC
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    (2R,4R)-APDC

    CAS:
    <p>(2R,4R)-APDC is a selective group II metabotropic glutamate receptors (mGluRs) agonist. It has anticonvulsant and neuroprotective effects.</p>
    Formula:C6H10N2O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:174.15

    Ref: TM-T10095

  • AMPA receptor modulator-2
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    AMPA receptor modulator-2

    CAS:
    <p>AMPA receptor modulator-2 is a modulator of AMPA receptor. The pIC50 value for TARPγ2 dependent AMPA receptor is 10.1.</p>
    Formula:C15H6F6N4OS
    Purity:99.8%
    Color and Shape:Solid
    Molecular weight:404.29

    Ref: TM-T37734

  • MK-8768
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    MK-8768

    CAS:
    <p>MK-8768 is a potent, selective, and orally bioavailable negative allosteric modulator of the mGluR2 class, exhibiting an IC50 of 9.6 nM and characterized by</p>
    Formula:C21H22F3N5O2
    Color and Shape:Solid
    Molecular weight:433.43

    Ref: TM-T79302

  • Philanthotoxin 74 dihydrochloride
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    Philanthotoxin 74 dihydrochloride

    CAS:
    <p>Philanthotoxin 74 dihydrochloride is an antagonist of AMPAR with IC50s of 263 and 296 nM for GluR3 and GluR1.</p>
    Formula:C24H44Cl2N4O3
    Purity:99.75%
    Color and Shape:Solid
    Molecular weight:507.54

    Ref: TM-T16524

  • VU6004909
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    VU6004909

    CAS:
    <p>VU6004909 is an mGlu5 receptor orthosteric modulator that reverses MK801-induced increased cortical activity and cognitive dysfunction.</p>
    Formula:C21H15FN2O4
    Purity:96.68% - 98.44%
    Color and Shape:Solid
    Molecular weight:378.35

    Ref: TM-T79784

  • Azotomycin
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    Azotomycin

    CAS:
    <p>Azotomycin is an antagonist of L-glutamine and may be used as an immunosuppressant.</p>
    Formula:C17H23N7O8
    Purity:98%
    Color and Shape:Solid
    Molecular weight:453.41

    Ref: TM-T26729

  • CVN636
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    CVN636

    CAS:
    <p>CVN636, a potent and selective allosteric agonist for the mGluR7 receptor, exhibits oral activity and CNS permeability [1], with an EC50 of 7 nM for human</p>
    Formula:C19H20FNO4S
    Color and Shape:Solid
    Molecular weight:377.43

    Ref: TM-T78090

  • LY2794193
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    LY2794193

    CAS:
    <p>LY2794193, a potent and selective mGlu3 receptor agonist, reduces akathisia seizures and increases GAT1, GLAST and GLT-1 protein levels in rats.</p>
    Formula:C16H18N2O6
    Purity:98.15%
    Color and Shape:Solid
    Molecular weight:334.32

    Ref: TM-T15807

  • LY367385 hydrochloride
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    LY367385 hydrochloride

    CAS:
    <p>LY367385 hydrochloride: selective mGluR1a antagonist, IC50 = 8.8 μM, neuroprotective, anticonvulsant, antiepileptic.</p>
    Formula:C10H12ClNO4
    Color and Shape:Solid
    Molecular weight:245.66

    Ref: TM-T60355

  • CymitQuimica logo
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    AZD 2066 hydrate

    <p>AZD 2066 hydrate is a selective, orally active, and brain-penetrant antagonist of mGluR5. It exhibits antinociceptive effects [1].</p>
    Formula:C19H18ClN5O3
    Color and Shape:Solid
    Molecular weight:386.33

    Ref: TM-T61708