GluR
Glutamate Receptor inhibitors are compounds that block the activity of glutamate receptors, which are the main excitatory neurotransmitter receptors in the brain. These receptors play a pivotal role in synaptic transmission, plasticity, learning, and memory. Dysregulation of glutamate signaling is associated with various neurological disorders, including epilepsy, stroke, and neurodegenerative diseases. GluR inhibitors are essential for investigating the mechanisms of excitotoxicity and developing neuroprotective strategies. At CymitQuimica, we offer a range of glutamate receptor inhibitors to support your research in synaptic function, neuroprotection, and cognitive disorders.
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(S)-3,4-DCPG HCl
(S)-3,4-DCPG HCl is a selective mGluR8a agonist, impacting AV12-664 cells with an EC50 of 31 …
Formula:
C10H10ClNO6
Purity:
99.06% - 99.90%
Color and Shape:
Soild
Molecular weight:
275.64
Ref: TM-T23288L
| 1mg | 180.00 € | ||
| 5mg | 454.00 € | ||
| 10mg | 645.00 € | ||
| 25mg | 1,012.00 € | ||
| 50mg | 1,384.00 € | ||
| 100mg | 1,830.00 € | ||
| 500mg | 3,692.00 € | ||
| 1mL*10mM (DMSO) | 412.00 € |
Estimated delivery in United States, on Monday 18 Nov 2024
(S)-3,4-DCPG
CAS:201730-11-2
(S)-3,4-DCPG ((S)-3,4-Dicarboxyphenylglycine) is a selective agonist of human metabotropic glutamate receptor 8a (mGluR8a).
Formula:
C10H9NO6
Purity:
98%
Color and Shape:
Solid
Molecular weight:
239.18
Ref: TM-T23288
| 1mg | 86.00 € | ||
| 5mg | 282.00 € | ||
| 10mg | 473.00 € |
Estimated delivery in United States, on Monday 18 Nov 2024
JNJ-46778212
CAS:1363281-27-9
JNJ-46778212 (VU 0409551) is a selective and potent mGlu5 allosteric modulator (EC50: 260 nM) for …
Formula:
C20H17FN2O3
Purity:
99.24%
Color and Shape:
Solid
Molecular weight:
352.36
Ref: TM-T15619
| 5mg | 61.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 199.00 € | ||
| 50mg | 339.00 € | ||
| 100mg | 544.00 € | ||
| 1mL*10mM (DMSO) | 68.00 € |
Estimated delivery in United States, on Monday 18 Nov 2024
EGLU
CAS:170984-72-2
EGLU, an antidepressant and potent mGluR-2 antagonist, binds with a 66 μM Kd to (lS,3S)-ACPD …
Formula:
C7H13NO4
Purity:
99.98%
Color and Shape:
Solid
Molecular weight:
175.18
Ref: TM-T11165
| 1mg | 273.00 € | ||
| 2mg | 406.00 € | ||
| 5mg | 673.00 € | ||
| 10mg | 919.00 € | ||
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € |
Estimated delivery in United States, on Monday 18 Nov 2024
GYKI 53655 hydrochloride
CAS:143692-48-2
GYKI 53655 hydrochloride (LY300168 hydrochloride) is an antagonist of AMPA and is used in the …
Formula:
C19H21ClN4O3
Purity:
98.02%
Color and Shape:
Solid
Molecular weight:
388.85
Ref: TM-T15456
| 1mg | 53.00 € |
Estimated delivery in United States, on Monday 18 Nov 2024
AMN082
CAS:97075-46-2
AMN082 is an mGluR7 agonist with antidepressant effects. Neuroprotective effect of AMN082 on neuronal apoptosis …
Formula:
C28H30Cl2N2
Purity:
97.23% - 98.34%
Color and Shape:
Solid
Molecular weight:
465.46
Ref: TM-T21935
| 1mg | 40.00 € | ||
| 5mg | 75.00 € | ||
| 10mg | 107.00 € | ||
| 25mg | 207.00 € |
Estimated delivery in United States, on Monday 18 Nov 2024
LY341495
CAS:201943-63-7
LY341495 is a potent metabotropic glutamate receptor antagonist and can be used to study neurological …
Formula:
C20H19NO5
Purity:
99.37%
Color and Shape:
Solid
Molecular weight:
353.37
Ref: TM-T15816
| 1mg | 46.00 € | ||
| 5mg | To inquire |
Estimated delivery in United States, on Monday 18 Nov 2024
NS-102
CAS:136623-01-3
NS-102 is a glutamate receptor and NMDA receptor antagonist that inhibits erythrocyanine (GluK2) and inhibits …
Formula:
C12H11N3O4
Purity:
98.73% - 98.95%
Color and Shape:
Solid
Molecular weight:
261.23
Ref: TM-T38779
| 1mg | 154.00 € | ||
| 5mg | 372.00 € | ||
| 10mg | 622.00 € | ||
| 25mg | 1,024.00 € | ||
| 50mg | 1,381.00 € | ||
| 100mg | 1,860.00 € |
Estimated delivery in United States, on Monday 18 Nov 2024
γ-DGG
CAS:6729-55-1
gamma-DGG is a competitive blocker of AMPA receptor.
Formula:
C7H12N2O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
204.18
Ref: TM-T15369
| 5mg | 46.00 € | ||
| 10mg | 60.00 € |
Estimated delivery in United States, on Monday 18 Nov 2024
GYKI 52466 dihydrochloride
CAS:2319722-40-0
GYKI 52466 dihydrochloride is an AMPA/Kainate receptor antagonist with anticonvulsant activity and can be used …
Formula:
C17H17Cl2N3O2
Purity:
99.38%
Color and Shape:
Solid
Molecular weight:
366.24
Ref: TM-T11522
| 2mg | 107.00 € |
Estimated delivery in United States, on Monday 18 Nov 2024
VU0422288
CAS:1630936-95-6
VU0422288 (ML396) is a type III mGlu receptor (mGlus) orthosteric modulator with inhibitory effects on …
Formula:
C17H11Cl2N3O2
Purity:
95.48%
Color and Shape:
Solid
Molecular weight:
360.19
Ref: TM-T29135
| 5mg | 79.00 € | ||
| 10mg | 119.00 € | ||
| 25mg | 231.00 € | ||
| 50mg | 370.00 € | ||
| 100mg | 603.00 € | ||
| 500mg | 1,243.00 € |
Estimated delivery in United States, on Monday 18 Nov 2024
CX717
CAS:867276-98-0
CX 717 is a positive allosteric modulator of AMPA receptor which has an antidepressant-like effect.
Formula:
C11H11N3O3
Purity:
100%
Color and Shape:
Soild
Molecular weight:
233.23
Ref: TM-T60201
| 10mg | 44.00 € | ||
| 25mg | 83.00 € | ||
| 50mg | 114.00 € | ||
| 100mg | 182.00 € | ||
| 200mg | 271.00 € |
Estimated delivery in United States, on Monday 18 Nov 2024
VU-29
CAS:890764-36-0
VU-29 is a positive allosteric mGlu5 receptor modulator with EC50=9 nM and Ki=244 nM for …
Formula:
C22H16N4O3
Purity:
99.63%
Color and Shape:
Solid
Molecular weight:
384.39
Ref: TM-T23515
| 2mg | 34.00 € | ||
| 5mg | 51.00 € | ||
| 10mg | 88.00 € | ||
| 25mg | 164.00 € | ||
| 50mg | 263.00 € | ||
| 100mg | 378.00 € | ||
| 200mg | 539.00 € | ||
| 1mL*10mM (DMSO) | 56.00 € |
Estimated delivery in United States, on Friday 22 Nov 2024
DNQX
CAS:2379-57-9
DNQX (FG 9041) is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 …
Formula:
C8H4N4O6
Purity:
97.15% - 99.10%
Color and Shape:
Off-White Powder With A Yellow Tinge
Molecular weight:
252.14
Ref: TM-T7304
| 25mg | 55.00 € | ||
| 50mg | 88.00 € | ||
| 100mg | 113.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Friday 22 Nov 2024
VU0364770
CAS:61350-00-3
VU0364770 (VU 0364770)(EC50=1.1 μM), a positive allosteric modulator(PAM) of mGlu4, shows insignificant activity at 68 …
Formula:
C12H9ClN2O
Purity:
99.66% - 99.92%
Color and Shape:
Solid
Molecular weight:
232.67
Ref: TM-T6727
| 5mg | 35.00 € | ||
| 10mg | 51.00 € | ||
| 25mg | 60.00 € | ||
| 50mg | 95.00 € | ||
| 100mg | 150.00 € | ||
| 200mg | 214.00 € | ||
| 1mL*10mM (DMSO) | 69.00 € |
Estimated delivery in United States, on Friday 22 Nov 2024
XAP044
CAS:196928-50-4
XAP044 blocks mGlu7, inhibiting long-term potentiation in mouse brain with a half-maximal effect at 88nm.
Formula:
C15H9IO4
Purity:
99.56%
Color and Shape:
Solid
Molecular weight:
380.13
Ref: TM-T21995
| 1mg | 40.00 € | ||
| 5mg | 73.00 € | ||
| 10mg | 126.00 € | ||
| 25mg | 216.00 € | ||
| 50mg | 326.00 € | ||
| 100mg | 465.00 € | ||
| 200mg | 645.00 € | ||
| 1mL*10mM (DMSO) | 90.00 € |
Estimated delivery in United States, on Friday 22 Nov 2024
Lu AF21934
CAS:1445605-23-1
Lu AF21934 is a brain-penetrant and selective mGlu4 receptor positive allosteric modulator (IC50: 500 nM, …
Formula:
C14H16Cl2N2O2
Purity:
97.96%
Color and Shape:
Solid
Molecular weight:
315.2
Ref: TM-T3539
| 1mg | 38.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 125.00 € | ||
| 25mg | 225.00 € | ||
| 50mg | 359.00 € | ||
| 100mg | 573.00 € | ||
| 1mL*10mM (DMSO) | 79.00 € |
Estimated delivery in United States, on Friday 22 Nov 2024
DL-AP3
CAS:20263-06-3
DL-AP3 is a competitive group I metabotropic glutamate receptor antagonist and inhibitor of phosphoserine phosphatase.
Formula:
C3H8NO5P
Purity:
98.18% - ≥98%
Color and Shape:
White Powder
Molecular weight:
169.07
Ref: TM-T22730
| 5mg | 34.00 € |
Estimated delivery in United States, on Friday 22 Nov 2024
(S)-ATPO
CAS:252930-37-3
(S)-ATPO is Competitive antagonist at GluR1-4 (AMPA-preferring) receptors.
Formula:
C11H19N2O7P
Purity:
98.37% - 99.41%
Color and Shape:
Solid
Molecular weight:
322.25
Ref: TM-T3473
| 1mg | 52.00 € | ||
| 2mg | 73.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 153.00 € | ||
| 25mg | 280.00 € | ||
| 50mg | 438.00 € | ||
| 100mg | 639.00 € |
Estimated delivery in United States, on Friday 22 Nov 2024
CDPPB
CAS:781652-57-1
CDPPB is a modulator of mGluR5 positive allosteric(with an EC50 of 27 nM in Chinese …
Formula:
C23H16N4O
Purity:
99.16%
Color and Shape:
Solid
Molecular weight:
364.4
Ref: TM-T22641
| 2mg | 37.00 € | ||
| 5mg | 56.00 € | ||
| 10mg | 91.00 € | ||
| 25mg | 147.00 € | ||
| 50mg | 240.00 € | ||
| 100mg | 359.00 € | ||
| 200mg | 510.00 € |
Estimated delivery in United States, on Friday 22 Nov 2024
