GluR
Glutamate Receptor inhibitors are compounds that block the activity of glutamate receptors, which are the main excitatory neurotransmitter receptors in the brain. These receptors play a pivotal role in synaptic transmission, plasticity, learning, and memory. Dysregulation of glutamate signaling is associated with various neurological disorders, including epilepsy, stroke, and neurodegenerative diseases. GluR inhibitors are essential for investigating the mechanisms of excitotoxicity and developing neuroprotective strategies. At CymitQuimica, we offer a range of glutamate receptor inhibitors to support your research in synaptic function, neuroprotection, and cognitive disorders.
Found 255 products of "GluR"
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Basimglurant
CAS:<p>Basimglurant (CTEP Derivative) is a potent, selective and orally available modulator of mGlu5 negative allosteric(Kd of 1.1 nM).</p>Formula:C18H13ClFN3Purity:98.35%Color and Shape:SolidMolecular weight:325.77Decoglurant
CAS:<p>Decoglurant (RO4995819) is a negative allosteric modulator of mGluR2 and mGluR3 and it also is developed as an antidepressant.</p>Formula:C21H11F6N5Purity:99.77%Color and Shape:SolidMolecular weight:447.34VU0650786
CAS:<p>VU0650786: selective mGlu3 NAM, CNS-penetrant, IC50 392 nM, shows antidepressant/anxiolytic effects in rodents.</p>Formula:C18H15ClFN5O2Purity:99.09%Color and Shape:SolidMolecular weight:387.8DHPG
CAS:<p>DHPG is a potent Group I mGluR agonist; doesn't affect Group II/III; linked to phospholipase D.</p>Formula:C8H9NO4Purity:99.55%Color and Shape:SolidMolecular weight:183.16Org-26576
CAS:<p>Org-26576 is a positive allosteric modulator of the AMPA receptor.</p>Formula:C11H12N2O2Purity:99.67%Color and Shape:SolidMolecular weight:204.23LY339434 HCl
<p>LY339434 HCl is a low affinity GluR5 erythrocyte receptor agonist.LY339434 HCl causes rapid neuronal death primarily by affecting N-methyl-D-aspartate (NMDA)</p>Formula:C18H20ClNO4Purity:97.96% - 99.68%Color and Shape:SoildMolecular weight:349.81Piracetam
CAS:<p>Piracetam (UCB-6215), a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), is used in therapy of the extensive cognitive disorders.</p>Formula:C6H10N2O2Purity:97.16%Color and Shape:Crystals From Isopropanol SolidMolecular weight:142.16γ-DGG acetate(6729-55-1 free base)
CAS:<p>gamma-DGG acetate(6729-55-1 free base) (γ-D-Glutamylglycine) is a competitive blocker of AMPA receptor.</p>Formula:C9H16N2O7Purity:99.81%Color and Shape:SolidMolecular weight:264.23(R)-ADX-47273
CAS:<p>(R)-ADX-47273 is a potent mGluR5 positive allosteric modulator(EC50 of 168 nM for potentiation ).</p>Formula:C20H17F2N3O2Purity:99.87%Color and Shape:SolidMolecular weight:369.36(R)-3,4-DCPG HCl
<p>(R)-3,4-DCPG HCl is a potent and selective mGlu8a receptor agonist that activates metabotropic glutamate receptors on primary afferent terminals in the neonatal</p>Formula:C10H10ClNO6Purity:98.80% - 99.89%Color and Shape:SoildMolecular weight:275.64AZD-8529 mesylate
CAS:<p>AZD-8529 mesylate is a highly selective, and orally bioavailable positive allosteric modulator of mGluR2 (EC50: 285 nM).</p>Formula:C25H28F3N5O6SPurity:99.19%Color and Shape:SolidMolecular weight:583.58KM02894
CAS:<p>KM02894 inhibits glutamate release, potentially reducing cancer-induced bone pain in tumor studies.</p>Formula:C7H9N3OS2Purity:99.98%Color and Shape:SolidMolecular weight:215.3NBQX disodium
CAS:<p>NBQX Disodium (FG9202 disodium) is a highly selective, competitive AMPA receptor antagonist with neuroprotective and anticonvulsant activity.</p>Formula:C12H6N4Na2O6SPurity:97.6% - 98.22%Color and Shape:SolidMolecular weight:380.2415LY3027788
CAS:<p>LY3027788, potent oral prodrug of LY3020371, is a strong mGlu2/3 antagonist with notable antidepressant effects.</p>Formula:C25H31F2NO11SColor and Shape:SolidMolecular weight:591.58LY3027788 hydrochloride
CAS:<p>LY3027788 HCl, potent oral prodrug of LY3020371, targets mGlu2/3 with antidepressant effects.</p>Formula:C25H32ClF2NO11SColor and Shape:SolidMolecular weight:628.03LY2812223
CAS:<p>LY2812223: selective mGlu2 agonist; binds mGlu2/mGlu3 (Ki=144/156 nM).</p>Formula:C10H12N4O4SPurity:98%Color and Shape:SolidMolecular weight:284.29ML353
<p>ML353 activates TREK-1/2, binds mGlu5 SAM (Ki=18.2 nM), surpasses 5mpep, may address SAM activity/blocking.</p>Formula:C19H15FN2OPurity:99.98% - 99.98%Color and Shape:SoildMolecular weight:306.33GYKI-47261 dihydrochloride
CAS:<p>GYKI-47261 dihydrochloride is an AMPA receptor antagonist and CYP2E1 inducer, demonstrating broad-spectrum anticonvulsant and neuroprotective activities.</p>Formula:C18H17Cl3N4Purity:98.32% - 99.14%Color and Shape:SolidMolecular weight:395.71mGluR5 modulator 1
CAS:<p>mGluR5 modulator 1 is a positive modulator for mGluR5, used in schizophrenia and cognitive research.</p>Formula:C18H19ClFN3O2Color and Shape:SolidMolecular weight:363.82JF-NP-26
<p>Releases pain-blocking raseglurant under 405 nm light. Inhibits Quisqualate. Analgesic in vivo. Quantum yield: 0.18.</p>Color and Shape:Solid
