GluR
Glutamate Receptor inhibitors are compounds that block the activity of glutamate receptors, which are the main excitatory neurotransmitter receptors in the brain. These receptors play a pivotal role in synaptic transmission, plasticity, learning, and memory. Dysregulation of glutamate signaling is associated with various neurological disorders, including epilepsy, stroke, and neurodegenerative diseases. GluR inhibitors are essential for investigating the mechanisms of excitotoxicity and developing neuroprotective strategies. At CymitQuimica, we offer a range of glutamate receptor inhibitors to support your research in synaptic function, neuroprotection, and cognitive disorders.
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Foliglurax
CAS:1883329-51-8
Foliglurax is a highly selective brain-penetrant metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) …
Formula:
C23H23N3O3S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
421.51
Ref: TM-T11311L
| 25mg | 1,410.00 € | ||
| 50mg | 1,852.00 € | ||
| 100mg | 2,338.00 € |
Estimated delivery in United States, on Monday 3 Feb 2025
BMT-145027
CAS:2018282-44-3
BMT-145027 is a positive allosteric modulator of mGluR5 without inherent agonist activity (EC50 = 47 …
Formula:
C23H14ClF3N4
Purity:
99.5%
Color and Shape:
Solid
Molecular weight:
438.83
Ref: TM-T10573
| 1mg | 45.00 € | ||
| 2mg | 60.00 € | ||
| 5mg | 90.00 € | ||
| 10mg | 152.00 € | ||
| 25mg | 244.00 € | ||
| 50mg | 346.00 € | ||
| 100mg | 442.00 € | ||
| 500mg | 910.00 € |
Estimated delivery in United States, on Monday 3 Feb 2025
VU6001376
CAS:1968546-34-0
VU6001376 is an effective and selective positive allosteric modulator of the metabotropic glutamate receptor 4 …
Formula:
C18H14F2N6OS
Purity:
98%
Color and Shape:
Solid
Molecular weight:
400.41
Ref: TM-T17248
| 25mg | 1,549.00 € | ||
| 50mg | 2,038.00 € | ||
| 100mg | 2,617.00 € |
Estimated delivery in United States, on Monday 3 Feb 2025
ML337
CAS:1443118-44-2
ML337 is a negative allosteric modulator of mGlu3 with an IC50 of 593 nM.
Formula:
C21H20FNO3
Purity:
99.09%
Color and Shape:
Solid
Molecular weight:
353.39
Ref: TM-T23003
| 1mg | 35.00 € | ||
| 5mg | 63.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 202.00 € | ||
| 50mg | 303.00 € | ||
| 100mg | To inquire | ||
| 1mL*10mM (DMSO) | 76.00 € |
Estimated delivery in United States, on Monday 3 Feb 2025
LY382884
CAS:211566-75-5
LY382884 is a selective and potent GluR5 kainate receptor antagonist with anxiolytic activity.LY382884 blocks blockade …
Formula:
C18H23NO4
Purity:
98.06% - 98.71%
Color and Shape:
Solid
Molecular weight:
317.38
Ref: TM-T27949
| 1mg | 696.00 € | ||
| 5mg | 1,467.00 € | ||
| 10mg | 1,840.00 € | ||
| 25mg | 2,398.00 € | ||
| 50mg | 2,965.00 € | ||
| 100mg | 4,008.00 € |
Estimated delivery in United States, on Monday 3 Feb 2025
NS 1209
CAS:205645-02-9
NS 1209 (SPD 502) is a AMPA receptor antagonist.
Formula:
C24H27N4NaO7S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
538.55
Ref: TM-T4009
| 25mg | 804.00 € |
Estimated delivery in United States, on Monday 3 Feb 2025
HexylHIBO
CAS:334887-43-3
HexylHIBO is a type I mGluR antagonist that inhibits mGlu1a and mGlu5a, with Kb values …
Formula:
C12H20N2O4
Purity:
99.48%
Color and Shape:
Solid
Molecular weight:
256.3
Ref: TM-T22840
| 1mg | 83.00 € | ||
| 5mg | 171.00 € | ||
| 10mg | 245.00 € | ||
| 25mg | 555.00 € | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 3 Feb 2025
Dasolampanel
CAS:503294-13-1
Dasolampanel (NGX-426) is an ionotropic glutamate receptor AMPA and Kainate receptor antagonist for the study …
Formula:
C17H20ClN5O3
Purity:
99%
Color and Shape:
Solid
Molecular weight:
377.83
Ref: TM-T31208
| 1mg | 722.00 € | ||
| 5mg | 1,486.00 € | ||
| 25mg | 2,735.00 € | ||
| 50mg | 3,532.00 € | ||
| 100mg | 4,859.00 € |
Estimated delivery in United States, on Monday 3 Feb 2025
(S)-MCPG
CAS:150145-89-4
(S)-MCPG is the active isomer of (RS)-MCPG, non-selective group I/group II metabotropic glutamate receptor antagonist.
Formula:
C10H11NO4
Purity:
98.72%
Color and Shape:
Solid
Molecular weight:
209.20
Ref: TM-T13452
| 1mg | 35.00 € | ||
| 5mg | To inquire |
Estimated delivery in United States, on Monday 3 Feb 2025
AZD6538
CAS:453566-30-8
AZD6538 is an mGluR5 negative allosteric modulator used in the study of CNS-related diseases such …
Formula:
C15H6FN5O
Purity:
98.68%
Color and Shape:
Solid
Molecular weight:
291.24
Ref: TM-T26719
| 1mg | 35.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 102.00 € | ||
| 25mg | 198.00 € | ||
| 50mg | 295.00 € | ||
| 100mg | 439.00 € |
Estimated delivery in United States, on Monday 3 Feb 2025
CBiPES hydrochloride
CAS:856702-40-4
CBiPES hydrochloride (CBiPES HCl) is an orthosteric modulator of the mGlu2 receptor and is used …
Formula:
C21H20ClN3O2S
Purity:
99.66%
Color and Shape:
Solid
Molecular weight:
413.92
Ref: TM-T22638
| 1mg | 167.00 € | ||
| 5mg | 407.00 € | ||
| 10mg | 591.00 € | ||
| 25mg | 916.00 € | ||
| 50mg | 1,227.00 € | ||
| 100mg | 1,664.00 € | ||
| 500mg | 3,336.00 € |
Estimated delivery in United States, on Monday 3 Feb 2025
CPCCOEt
CAS:179067-99-3
CPCCOEt is a low affinity, selective, non-competitive and reversible antagonist of mGluR1b
Formula:
C13H13NO4
Purity:
99.87%
Color and Shape:
Solid
Molecular weight:
247.25
Ref: TM-T22692
| 5mg | 52.00 € | ||
| 10mg | 72.00 € | ||
| 25mg | 131.00 € | ||
| 50mg | 207.00 € | ||
| 100mg | 306.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Monday 3 Feb 2025
S 18986
CAS:175340-20-2
S 18986 is a selective, orally active, brain penetrant positive allosteric modulator of AMPA-type receptors, …
Formula:
C10H12N2O2S
Purity:
99.25%
Color and Shape:
Solid
Molecular weight:
224.28
Ref: TM-T16816
| 1mg | 35.00 € | ||
| 5mg | 63.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 3 Feb 2025
VU 0285683
CAS:327056-22-4
VU 0285683 is a specific negative allosteric modulator of mGluR5 with a high affinity for …
Formula:
C14H7FN4O
Purity:
99.8%
Color and Shape:
Solid
Molecular weight:
266.23
Ref: TM-T23509
| 1mg | 63.00 € | ||
| 5mg | 134.00 € | ||
| 10mg | 165.00 € | ||
| 25mg | 270.00 € | ||
| 50mg | 385.00 € | ||
| 100mg | 548.00 € | ||
| 500mg | 1,090.00 € | ||
| 1mL*10mM (DMSO) | 152.00 € |
Estimated delivery in United States, on Monday 3 Feb 2025
TC-N 22A
CAS:1314140-00-5
TC-N 22A is a strong, selective, oral active mGlu4 forward allosteric regulator (PAM) that can …
Formula:
C14H13N5S
Purity:
99.84%
Color and Shape:
Solid
Molecular weight:
283.35
Ref: TM-T23440
| 1mg | 119.00 € | ||
| 5mg | 246.00 € | ||
| 10mg | 302.00 € | ||
| 25mg | 509.00 € | ||
| 50mg | 734.00 € | ||
| 100mg | 1,009.00 € |
Estimated delivery in United States, on Monday 3 Feb 2025
LSN2463359
CAS:1401031-52-4
LSN2463359 is a positive allosteric modulators of the mGlu5 receptor.
Formula:
C16H15N3O
Purity:
99.36%
Color and Shape:
Solid
Molecular weight:
265.31
Ref: TM-T27854
| 2mg | 35.00 € | ||
| 5mg | 52.00 € | ||
| 10mg | 83.00 € | ||
| 25mg | 166.00 € | ||
| 50mg | 253.00 € | ||
| 100mg | 373.00 € | ||
| 200mg | 530.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Monday 3 Feb 2025
LYPLAL1-IN-1
CAS:1966129-74-7
LYPLAL1-IN-1 is a selective covalent small-molecule inhibitor of Lysophospholipase-like 1 (IC50: 0.006 μM). LYPLAL1-IN-1 also …
Formula:
C29H29N7O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
539.59
Ref: TM-T15823
| 25mg | To inquire | ||
| 50mg | To inquire | ||
| 100mg | To inquire |
Estimated delivery in United States, on Monday 3 Feb 2025
DMeOB
CAS:40252-74-2
DMeOB (3,3'-Dimethoxybenzaldazine) is a negative regulator with mGluR5 agonist activity and is used in the …
Formula:
C16H16N2O2
Purity:
98.34%
Color and Shape:
Solid
Molecular weight:
268.31
Ref: TM-T22736
| 1mg | 35.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 102.00 € | ||
| 25mg | 198.00 € | ||
| 50mg | 305.00 € | ||
| 100mg | 461.00 € | ||
| 500mg | 995.00 € | ||
| 1mL*10mM (DMSO) | 84.00 € |
Estimated delivery in United States, on Monday 3 Feb 2025
CPPHA
CAS:693288-97-0
CPPHA, a positive allosteric modulator of glutamate receptors mGluR5 and mGluR1, is commonly used in …
Formula:
C22H15ClN2O4
Purity:
99.61%
Color and Shape:
Solid
Molecular weight:
406.82
Ref: TM-T10881
| 5mg | 39.00 € | ||
| 10mg | 63.00 € | ||
| 25mg | To inquire | ||
| 50mg | To inquire | ||
| 1mL*10mM (DMSO) | 43.00 € |
Estimated delivery in United States, on Monday 3 Feb 2025
Valiglurax
CAS:1976050-09-5
Valiglurax (VU2957), potent mGlu4 PAM, crosses blood-brain barrier, orally available; promising for Parkinson's treatment.
Formula:
C16H10F3N5
Purity:
97.38%
Color and Shape:
Solid
Molecular weight:
329.28
Ref: TM-T35028
| 5mg | 50.00 € | ||
| 10mg | 79.00 € | ||
| 25mg | 152.00 € | ||
| 50mg | 251.00 € | ||
| 100mg | 365.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Monday 3 Feb 2025
